CARDIOVASCULAR DISEASES

Clinical and Translational Cardiology

Main lines of research

  • Electrophysiology and arrhythmias clinical and experimental.
  • Heart failure.
  • Ischemic heart disease.
  • Valvular heart disease.
  • Cardiac imaging.
  • Percutaneous valve repair.

Challenges

Electrophysiology

  • Describe the mechanisms and clinical significance of the electrocardiographic alterations in patients with acute myocardial infarction, using translational research in pig heart models.
  • Characterize the ECG patterns and prognosis in patients with left circumflex coronary occlusion.
  • Describe the behaviour of myocardial electrical impedance in normal and acute ischemic models using new bioimpedance methods developed in our laboratory.

Heart failure

  • Develop new risk scores for ambulatory heart failure patients predicting death and re-hospitalizations.
  • Research on new biomarkers in patients with heart failure included in the Spanish registry Redinscor II (RIC) (1500 patients). Our group is the national coordinator.
  • Develop new markers for early detection of cardiac graft rejection in transplanted patients.
  • Develop palliative care programs for patients with advanced heart failure.

Ischaemic heart disease

  • Settle a Program for patients with refractory angina.
  • Treat complex atherosclerotic coronary artery lesions using international techniques.

Valvular heart disease

  • Implement new percutaneous techniques for the treatment of mitral valve regeneration and degenerative aortic stenosis.
  • Implement devices for the treatment of prosthetic valve leak.

Cardiac imaging

  • Implement new imaging software analysis to detect structural abnormalities of the myocardium (fibrosis, necrosis).
  • Implement new software analysis for fusion imaging in patients submitted to coronary interventions.
  • Implement new percutaneous techniques for the treatment of mitral regurgitation in patients with heart failure or myocardial infarction.

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