TRANSLATIONAL MEDICINE

Digestive Diseases

Main lines of research

Experimental research

  • Experimental rat model of cirrhosis and ascites.
  • Mechanisms and prevention of bacterial translocation in rats with cirrhosis.
  • Experimental model of spontaneous and induced bacterial peritonitis: physiopathology and treatment.
  • MiRNAs expression profile in inflammatory bowel disease after stimulation with toll-like receptor ligands.

Clinical investigation

  • Physiopathology, diagnosis, treatment and prevention of bacterial infections, ascites and hepatorenal syndrome in cirrhosis.
  • Diagnosis and treatment of hepatic encephalopathy in cirrhosis.
  • Cognitive impairment, falls and quality of life in patients with cirrhosis.
  • Physiopathology, diagnosis, treatment and prevention of digestive haemorrhage due to portal hypertension of non varicose origin.
  • Diagnosis and treatment of chronic hepatitis B and C.
  • Diagnosis and treatment of hepatocarcinoma.
  • Physiopathology, diagnosis and treatment of intestinal inflammatory disease (inflammatory bowel disease).
  • Diagnosis and treatment in advanced gastrointestinal endoscopy.
  • Diagnosis and treatment of acute pancreatitis.
  • Prevention of acute post-ERCP pancreatitis.
  • Chronic pancreatitis and pancreatic neoplasms: molecular studies, early detection and treatment.

Challenges

  • Consolidate the CIBEREHD research group by studying complications in cirrhosis.
  • Expand the hepatology research lab and develop new research.
  • Consolidate the portal hypertension research group.
  • Consolidate the pancreatic illness research line.
  • Consolidate the inflammatory bowel disease research line.
  • Consolidate the polyps and colon cancer research line.
  • Develop a digestive endoscopy research line.

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