Sant Pau - Institut de Recerca

Main lines of research

Biomaterials: comparative study of two different cranial bone fixations.
Tumour biology: gliomas (prognostic value of different mutations in anaplastic astrocytoma and GBM), pituitary gland adenomas.
Biomarkers in anaplastic astrocytomas and glioblastoma multiforme.
Anatomy of the skull base.
Clinical evaluation of neurostimulation techniques in different neurological entities (treatment-resistant depression and neuropathic pain).

Challenges

Monitor the clinical trial on treatment-resistant depression treated using deep brain stimulation techniques (jointly with psychiatry).
Evaluate neurostimulation for other disorders: cluster headache.

Group coordination

MUÑOZ HERNANDEZ, FERNANDO FGS
fmunoz@santpau.cat

Members

Aibar Duran, Juan Angel FGS

Anka , Michael Oladotun FGS

Borras Pino, Xavier FGS

De Quintana Schmidt, Cristian Jose FGS

Freixer Palau, Berta FGS

Leidinger, Andreas FGS

Patino Alvarado, Juan Diego FGS

Perales Susan, Mario IR

Rico Pereira, Marta FGS

Rodriguez Rodriguez, Rodrigo FGS

Roig Arsequell, Clara FGS

Sanchez Nevado, Raquel FGS

Tello Vicente, Jose Antonio FGS

Publications 2022

(JIF 2022)

Aibar JA, Oladotun M, Asencio C, Valassi E, Webb S, Gras JR, Monserrat J, Ribo PT, Munoz F. Complication Rates after Endoscopic Transsphenoidal Surgery for ACTH-Secreting Pituitary Adenomas: A Comparative Analysis with GH and Nonfunctioning Adenomas. Journal of Neurological Surgery Part B-Skull Base. 2022; 83. DOI:10.1055/s-0041-1725029. PMID:35832977. IF:0,9 (Q4/9D). Document type: Article.
Aibar JÁ, Rodríguez R, de Diego FJ, Portella MJ, Álvarez MJ, Martín A, Puigdemont D, Molet J. Long-Term Results of Deep Brain Stimulation for Treatment-Resistant Depression: Outcome Analysis and Correlation With Lead Position and Electrical Parameters. Neurosurgery. 2022; 90(1). DOI:10.1227/NEU.0000000000001739. PMID:34982873. IF:4,8 (Q1/1D). Document type: Article.
Anania P, Lucas RM, Todaro G, Zona G, Cortes CA, Hernandez FM. Anatomical meningo-orbital band evaluation and clinical implications: a cadaveric dissection study. Journal of Neurosurgical Sciences. 2022; 66(3). DOI:10.23736/S0390-5616.19.04794-5. PMID:31738027. IF:1,9 (Q3/6D). Document type: Article.
de Quintana C, Salgado L, Aibar JA, Holzapfel M, Cortes CA, Alvarado JDP, Rodriguez RR, Teixido JM. Neuronavigated Ultrasound in Neuro-Oncology: A True Real-Time Intraoperative Image. World Neurosurgery. 2022; 157. DOI:10.1016/j.wneu.2021.10.082. PMID:34655818. IF:2 (Q3/6D). Document type: Article.
Gandia ML, Vinuela JM, Barrios L, Alarcon C, Arikan F, Arraez C, Dominguez CJ, Alen JF, Gutierrez R, Horcajadas A, Hernandez FM, Narvaez A, Paredes I, Perez R, de Lope AR, Ruiz F, Arrieta FJS, Tejada S, Tamarit M, Topczewski T, Lafuente J. Neurosurgical emergency management during the lockdown period in health care regions in Spain with different COVID-19 impact: lessons learned to improve outcomes on the future waves. European Journal of Trauma and Emergency Surgery. 2022; 48(3). DOI:10.1007/s00068-021-01767-0. PMID:34401937. IF:2,1 (Q3/6D). Document type: Article.
Mendez I, Sintes A, Pascual JC, Punti J, Lara A, Briones L, Nicolaou S, Schmidt C, Romero S, Fernandez M, Farres C, Soler J, Santamarina P, Vega D. Borderline personality traits mediate the relationship between low perceived social support and non-suicidal self-injury in a clinical sample of adolescents. JOURNAL OF AFFECTIVE DISORDERS. 2022; 302. DOI:10.1016/j.jad.2022.01.065. PMID:35038480. IF:6,6 (Q1/2D). Document type: Article.

Publications 2021

Aibar JA, Holzapfel M, Rodriguez RR, Nieto RB, Arnall CR, Teixido JM. Occipital nerve stimulation and deep brain stimulation for refractory cluster headache: a prospective analysis of efficacy over time. JOURNAL OF NEUROSURGERY. 2021; 134(2). DOI:10.3171/2019.11.JNS192042. PMID:31952039. IF:5,408.
Aibar JA, Munoz F, Asencio C, Montserrat J, Gras JR, Mirapeix RM. Intracavernous Branches of the Internal Carotid Artery Through an Endoscopic Endonasal Approach: Anatomical Study and Review of the Literature. World Neurosurgery. 2021; 151. DOI:10.1016/j.wneu.2021.04.046. PMID:33887498. IF:2,210.
Anania P, Mirapeix R, Zona G, Prior A, Cortes CA, Hernandez FM. Middle Cranial Fossa Approach: Anatomical Study on Skull Base Triangles as a Landmark for a Safe Anterior Petrosectomy. Journal of Neurological Surgery Part B-Skull Base. 2021; 82(02). DOI:10.1055/s-0039-1696957. PMID:33777635. IF:1,407.
Belvís R, Irimia P, Seijo-Fernández F, Paz J, García-March G, Santos-Lasaosa S, Latorre G, González-Oria C, Rodríguez R, Pozo-Rosich P, Láinez JM. Neuromodulation in headache and craniofacial neuralgia: guidelines from the Spanish Society of Neurology and the Spanish Society of Neurosurgery. Neurologia. 2021;36(1):61-79. DOI:10.1016/j.nrl.2020.04.022. PMID: 32718873. IF:5,486.
Esteve A, Alameda F, Carrato C, Pineda E, Arpi O, Martinez M, Mallo M, Gut M, Dabad M, Tortosa A, Del Barco S, Capellades J, Puig J, Gallego O, Pujol T, Oleaga L, Gil M, de Quintana C, Valduvieco I, Martinez A, Bellosillo B, Munoz AM, Esteve A, Domenech M, Camins A, Craven J, Villa S, Marruecos J, Domenech S, de la Iglesia N, Balana C, Bagué S, Aldecoa I. RNA sequencing and Immunohistochemistry Reveal ZFN7 as a Stronger Marker of Survival than Molecular Subtypes in G-CIMP-negative Glioblastoma. CLINICAL CANCER RESEARCH. 2021; 27(2). DOI:10.1158/1078-0432.CCR-20-2141. PMID:33106291. IF:13,801.
Pereira MR, Cortes CA. Primary Nocardia brain abscesses and role of intraventricular antibiotic therapy. CLINICAL NEUROLOGY AND NEUROSURGERY. 2021; 208:106846. DOI:10.1016/j.clineuro.2021.106846. PMID:34358801. IF:1,885.

Scientific Report 2017-Neurosurgery

Introduction

Main lines of research

Biomaterials: comparative study of two different cranial bone fixations.
Tumour biology: gliomas (prognostic value of different mutations in anaplastic astrocytoma and GBM), pituitary gland adenomas.
Biomarkers in anaplastic astrocytomas and glioblastoma multiforme.
Anatomy of the skull base.
Clinical evaluation of neurostimulation techniques in different neurological entities (treatment-resistant depression and neuropathic pain).

Challenges

Monitor the clinical trial on treatment-resistant depression treated using deep brain stimulation techniques (jointly with psychiatry).
Evaluate neurostimulation for other disorders: cluster headache.

Team

Group coordination

MUÑOZ HERNANDEZ, FERNANDO FGS
fmunoz@santpau.cat

Members

Aibar Duran, Juan Angel FGS

Anka , Michael Oladotun FGS

Borras Pino, Xavier FGS

De Quintana Schmidt, Cristian Jose FGS

Freixer Palau, Berta FGS

Leidinger, Andreas FGS

Patino Alvarado, Juan Diego FGS

Perales Susan, Mario IR

Rico Pereira, Marta FGS

Rodriguez Rodriguez, Rodrigo FGS

Roig Arsequell, Clara FGS

Sanchez Nevado, Raquel FGS

Tello Vicente, Jose Antonio FGS

Scientific output

Publications 2022

(JIF 2022)

Aibar JA, Oladotun M, Asencio C, Valassi E, Webb S, Gras JR, Monserrat J, Ribo PT, Munoz F. Complication Rates after Endoscopic Transsphenoidal Surgery for ACTH-Secreting Pituitary Adenomas: A Comparative Analysis with GH and Nonfunctioning Adenomas. Journal of Neurological Surgery Part B-Skull Base. 2022; 83. DOI:10.1055/s-0041-1725029. PMID:35832977. IF:0,9 (Q4/9D). Document type: Article.
Aibar JÁ, Rodríguez R, de Diego FJ, Portella MJ, Álvarez MJ, Martín A, Puigdemont D, Molet J. Long-Term Results of Deep Brain Stimulation for Treatment-Resistant Depression: Outcome Analysis and Correlation With Lead Position and Electrical Parameters. Neurosurgery. 2022; 90(1). DOI:10.1227/NEU.0000000000001739. PMID:34982873. IF:4,8 (Q1/1D). Document type: Article.
Anania P, Lucas RM, Todaro G, Zona G, Cortes CA, Hernandez FM. Anatomical meningo-orbital band evaluation and clinical implications: a cadaveric dissection study. Journal of Neurosurgical Sciences. 2022; 66(3). DOI:10.23736/S0390-5616.19.04794-5. PMID:31738027. IF:1,9 (Q3/6D). Document type: Article.
de Quintana C, Salgado L, Aibar JA, Holzapfel M, Cortes CA, Alvarado JDP, Rodriguez RR, Teixido JM. Neuronavigated Ultrasound in Neuro-Oncology: A True Real-Time Intraoperative Image. World Neurosurgery. 2022; 157. DOI:10.1016/j.wneu.2021.10.082. PMID:34655818. IF:2 (Q3/6D). Document type: Article.
Gandia ML, Vinuela JM, Barrios L, Alarcon C, Arikan F, Arraez C, Dominguez CJ, Alen JF, Gutierrez R, Horcajadas A, Hernandez FM, Narvaez A, Paredes I, Perez R, de Lope AR, Ruiz F, Arrieta FJS, Tejada S, Tamarit M, Topczewski T, Lafuente J. Neurosurgical emergency management during the lockdown period in health care regions in Spain with different COVID-19 impact: lessons learned to improve outcomes on the future waves. European Journal of Trauma and Emergency Surgery. 2022; 48(3). DOI:10.1007/s00068-021-01767-0. PMID:34401937. IF:2,1 (Q3/6D). Document type: Article.
Mendez I, Sintes A, Pascual JC, Punti J, Lara A, Briones L, Nicolaou S, Schmidt C, Romero S, Fernandez M, Farres C, Soler J, Santamarina P, Vega D. Borderline personality traits mediate the relationship between low perceived social support and non-suicidal self-injury in a clinical sample of adolescents. JOURNAL OF AFFECTIVE DISORDERS. 2022; 302. DOI:10.1016/j.jad.2022.01.065. PMID:35038480. IF:6,6 (Q1/2D). Document type: Article.

Publications 2021

Aibar JA, Holzapfel M, Rodriguez RR, Nieto RB, Arnall CR, Teixido JM. Occipital nerve stimulation and deep brain stimulation for refractory cluster headache: a prospective analysis of efficacy over time. JOURNAL OF NEUROSURGERY. 2021; 134(2). DOI:10.3171/2019.11.JNS192042. PMID:31952039. IF:5,408.
Aibar JA, Munoz F, Asencio C, Montserrat J, Gras JR, Mirapeix RM. Intracavernous Branches of the Internal Carotid Artery Through an Endoscopic Endonasal Approach: Anatomical Study and Review of the Literature. World Neurosurgery. 2021; 151. DOI:10.1016/j.wneu.2021.04.046. PMID:33887498. IF:2,210.
Anania P, Mirapeix R, Zona G, Prior A, Cortes CA, Hernandez FM. Middle Cranial Fossa Approach: Anatomical Study on Skull Base Triangles as a Landmark for a Safe Anterior Petrosectomy. Journal of Neurological Surgery Part B-Skull Base. 2021; 82(02). DOI:10.1055/s-0039-1696957. PMID:33777635. IF:1,407.
Belvís R, Irimia P, Seijo-Fernández F, Paz J, García-March G, Santos-Lasaosa S, Latorre G, González-Oria C, Rodríguez R, Pozo-Rosich P, Láinez JM. Neuromodulation in headache and craniofacial neuralgia: guidelines from the Spanish Society of Neurology and the Spanish Society of Neurosurgery. Neurologia. 2021;36(1):61-79. DOI:10.1016/j.nrl.2020.04.022. PMID: 32718873. IF:5,486.
Esteve A, Alameda F, Carrato C, Pineda E, Arpi O, Martinez M, Mallo M, Gut M, Dabad M, Tortosa A, Del Barco S, Capellades J, Puig J, Gallego O, Pujol T, Oleaga L, Gil M, de Quintana C, Valduvieco I, Martinez A, Bellosillo B, Munoz AM, Esteve A, Domenech M, Camins A, Craven J, Villa S, Marruecos J, Domenech S, de la Iglesia N, Balana C, Bagué S, Aldecoa I. RNA sequencing and Immunohistochemistry Reveal ZFN7 as a Stronger Marker of Survival than Molecular Subtypes in G-CIMP-negative Glioblastoma. CLINICAL CANCER RESEARCH. 2021; 27(2). DOI:10.1158/1078-0432.CCR-20-2141. PMID:33106291. IF:13,801.
Pereira MR, Cortes CA. Primary Nocardia brain abscesses and role of intraventricular antibiotic therapy. CLINICAL NEUROLOGY AND NEUROSURGERY. 2021; 208:106846. DOI:10.1016/j.clineuro.2021.106846. PMID:34358801. IF:1,885.

NEUROLOGICAL DISEASES, NEUROSCIENCE & MENTAL HEALTH

Neurosurgery

Main lines of research

Challenges

Group coordination

Members

Publications 2022

Publications 2021

Main lines of research

Challenges

Group coordination

Members

Publications 2022

Publications 2021

Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau