Sant Pau - Institut de Recerca

Principales líneas de investigación

Metabolismo óseo y osteoporosis

Análisis de la influencia genética sobre la osteoporosis mediante estudios de agregación de familias de 3 o más generaciones con un mínimo de 15 miembros.
Estudio de la estructura ósea con TC cuantitativa de la cadera y la columna vertebral, análisis de la contribución de los componentes trabecular y cortical mediante TCAR.
Descripción de los valles y los porcentajes de grasa en una población normal.
Análisis de la influencia del ejercicio físico en cambios en el compartimento muscular de pacientes con cirrosis medido con DXA y HRQCT (en colaboración con el Departamento gastroenterológica).
Descripción de la estructura ósea en pacientes con historia de acromegalia evaluada con DCA y HRQCT.

Hipertensión y riesgo vascular

Hipertensión y calidad de vida.
Hipertensión refractaria.
Uso de alirocumab en hipercolesterolemia.

Gestión clínica, medicina interna y geriatría

Índice de calidad asistencial (mortalidad, readmisiones, etc.).
Medicina perioperatoria.
Prescripción potencialmente inapropiada en pacientes mayores ingresados en el hospital.

Reumatología y artritis reumatoide

Artritis reumatoide precoz
Biomarcadores de artritis reumatoide
Neumopatía intersticial asociada a la artritis reumatoide

Esclerosis sistémica

Patrón y correlación de capilaroscopia con autoanticuerpos y tests de función pulmonar.
Detección de hipertensión arterial pulmonar en esclerosis sistémica basada en la evidencia: estudio DETECT.
Uso de antagonismo por los receptores de la endotelina para prevenir hipertensión arterial pulmonar (en colaboración con el Hospital Universitario del Valle de Hebrón).
Estudios genéticos de esclerosis sistémica y colaboración con Registro DUO y estudio LAUDOS.
Estudio del patrón de capilaroscopia en conectivopatías difusas: estudio QuantiCAP.

Gota

Epidemiología de la hiperuricemia y gota.

Síndrome de Sjögren

Hallazgos clínicos y epidemiológicos en pacientes españoles con síndrome de Sjögren primario (en colaboración con la Sociedad Española de Reumatología).

Retos

Establecer relaciones laborales estables entre los Grupos de Metabolismo Óseo y de Genómica de las Enfermedades Complejas del Hospital de la Santa Creu i Sant Pau y la Unidad de Metabolismo Óseo del Hospital del Mar – Instituto Municipal de Investigación Biomédica y la Facultad de Biología de la Universidad de Barcelona.
Fortalecer los lazos entre los departamentos de reumatología e inmunología en relación al estudio de enfermedades inmunológicas.

Coordinación del grupo

COROMINAS MACIAS, HECTOR FGS
hcorominas@santpau.cat

Miembros

Arroyo Diaz, Juan Antonio FGS
Barcelo Trias, Montserrat FGS
Bernardez Moreno, Julia IR
Casademont Pou, Jordi FGS
Castellvi Barranco, Ivan FGS
Diaz Torne, Cesar FGS
Dutren Tella, Adriana IR
Hernandez de Sosa, Nerea FGS
Laiz Alonso, Ana Maria FGS
Magallares Lopez, Berta Paula FGS
Malouf Sierra, Jorge IR
Moya Alvarado, Patricia FGS
Ros Abarca, Sandra IR
Santos Gutierrez, Alvaro FGS
Sihuro Cervantes, Margarita IR
Torres Bonafonte, Olga Herminia FGS

Publicaciones 2022

(JIF 2022)

Alvarado PM, de Oro JJD, Espinar MA, Perez EA, Perez NB, Carmona L, Burgos EC, Poch TC, Aguilera AC, Mendieta ED, Alarcon PE, Casares EG, Perez SH, Lopez BM, Morillo MM, Soria LM, Pastor CM, Martinez MM, Fernandez AP, Busquets MP, Garcia JR, Sanz DR, Lizarzaburu MS, Santo Panero P, Alierta ES, Roc MV, Macias HC. Interobserver reliability of Masei index validation by a multicenter collaborative group of rheumatologists. RHEUMATOLOGY INTERNATIONAL. 2022; 42(3). DOI:10.1007/s00296-020-04733-y. PMID:33146762. IF:4 (Q2/5D). Document type: Article.
Balius R, Pujol M, Perez D, Morros C, Susin A, Corominas H, Sala X. Sciatic nerve movement in the deep gluteal space during hip rotations maneuvers. CLINICAL ANATOMY. 2022; 35(4). DOI:10.1002/ca.23828. PMID:34913517. IF:2,4 (Q2/4D). Document type: Article.
Balsa A, González I, Sanmartí R, Corominas H. How do Spanish Rheumatologists handle remission? Survey of knowledge and approach before and after a training workshop. Reumatologia Clinica. 2022; 18(9). DOI:10.1016/j.reuma.2021.08.002, DOI (English Edition):10.1016/j.reumae.2021.08.002. PMID:34489191. Document type: Letter.
Calabria M, Garcia C, Grunden N, Pons C, Arroyo JA, Gomez B, Garcia M, Belvis R, Morollon N, Igual JV, Mur I, Pomar V, Domingo P. Post-COVID-19 fatigue: the contribution of cognitive and neuropsychiatric symptoms. JOURNAL OF NEUROLOGY. 2022; 269(8). DOI:10.1007/s00415-022-11141-8. PMID:35488918. IF:6 (Q1/2D). Document type: Article.
Calvo J, Pou J. Continuing medical education. An opportunity to continue improving. MEDICINA CLINICA. 2022; 159(1). DOI:10.1016/j.medcli.2022.03.012. PMID:35636993. IF:3,9 (Q2/4D). Document type: Editorial material.
Castellvi I, Castillo D, Corominas H, Mariscal A, Orozco S, Benito N, Pomar V, Baucells A, Mur I, de la Rosa D, Lobo D, Millan AM, de Sosa NH, Filella D, Matas L, Martinez L, Juarez C, Casademont J, Domingo P. Krebs von den Lungen-6 glycoprotein circulating levels are not useful as prognostic marker in COVID-19 pneumonia: A large prospective cohort study. Frontiers in Medicine. 2022; 9:973918. DOI:10.3389/fmed.2022.973918. PMID:36004366. IF:3,9 (Q2/4D). Document type: Article.
Castellví I, Vidal S, Valenzuela C. Autoimmunity in the Study of Interstitial Lung Disease: Are Serological Test Enough?. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(8). DOI:10.1016/j.arbres.2021.08.016. PMID:35312568. IF:8 (Q1/2D). Document type: Editorial material.
Cendon L, Rafecas A, De La Rosa D, Castellví I, Spagnolo P, Castillo D. Systematic Review of Systemic Corticosteroids for Treatment of Organizing Pneumonia. Open Respiratory Archives. 2022; 4(4):100211. DOI:10.1016/j.opresp.2022.100211. Document type: Article.
Cobo T, Sánchez C, Nuño L, Castellví I, Carrión I, Romero F, Narváez J, Trallero E, Tomero E, Ruiz ME, Larena C, Carrasco C, Jovaní V, Barbadillo C, Sivera F, Belzunegui J, Pérez A, Gómez A, Delgado E, Pego JM, Joven B, Ibáñez M, Martínez O, Ruiz A, Camins J, Ortega R, Trenor P, Rodríguez M, Freire M, Alcocer P, Holgado S, Rúa I, Lozano N, Martínez J. Myo-Spain: Spanish Registry of Patients with Idiopathic Inflammatory Myopathy. Methodology. Reumatologia Clinica. 2022; 18(5). DOI:10.1016/j.reuma.2021.01.007. PMID:33867271. Document type: Article.
de la Calle C, Rodriguez J, Ciudad L, Ramirez J, Celis R, Azuaga AB, Cuervo A, Graell E, Perez C, Diaz C, Salvador G, Gomez JA, Haro I, Sanmarti R, Canete JD, Ballestar E. The synovial and blood monocyte DNA methylomes mirror prognosis, evolution, and treatment in early arthritis. JCI Insight. 2022; 7(9):e158783. DOI:10.1172/jci.insight.158783. PMID:35324478. IF:8 (Q1/2D). Document type: Article.
De Miguel E, Sanchez JT, Estrada P, Munoz A, Martinez CV, Alvarado PM, Garcia MJ, Angeles V, Da CGL, Frutos AR, Ivorra J, Arrabal SL, Rocha MV, Iniguez CL, Garcia M, Molina C, Villar MA, Mas AJ, Gonzalez MA, Blanco R. Influence of the EULAR recommendations for the use of imaging in large vessel vasculitis in the diagnosis of giant cell arteritis: results of the ARTESER register. RMD Open. 2022; 8(2):e002507. DOI:10.1136/rmdopen-2022-002507. PMID:36597988. IF:6,2 (Q1/2D). Document type: Article.
Fernández SP, Rodríguez F, Laiz A, Castellví I, Magallares B, Corominas H. Impact of the COVID-19 pandemic on rheumatology nursing consultation. Reumatologia Clinica. 2022; 18(4). DOI:10.1016/j.reuma.2021.02.003. PMID:34088653. Document type: Article.
Franco T, Torres OH, Saez ME, Boera G, Santos Á, Clotet S, Albert D, El Y, Agustí M, Casademont J, Juárez C, Martínez L. Early differentiated CD28(+) CD27(+) T lymphocytes as a biomarker for short and long-term outcomes in older patients with pneumonia. JOURNAL OF LEUKOCYTE BIOLOGY. 2022; 112(5). DOI:10.1002/JLB.5MA0422-370R. PMID:35748037. IF:5,5 (Q2/3D). Document type: Article.
Galindo R, Bou R, Mir C, Martínez S, Magallares B, López M. Effectiveness and safety of bisphosphonates therapy in secondary osteoporosis in children. ANALES DE PEDIATRIA. 2022; 97(3). DOI:10.1016/j.anpedi.2021.09.008. PMID:35915035. IF:2,1 (Q3/6D). Document type: Article.
Garcia C, Calabria M, Grunden N, Pons C, Arroyo JA, Gomez B, Lleo A, Alcolea D, Belvis R, Morollon N, Mur I, Pomar V, Domingo P. Neuropsychological deficits in patients with cognitive complaints after COVID-19. Brain and Behavior. 2022; 12(3):e2508. DOI:10.1002/brb3.2508. PMID:35137561. IF:3,1 (Q2/3D). Document type: Article.
Gomez JA, Lobo D, Perez C, Ponce A, Frade B, Arciniegas A, Ojeda F, Ruiz V, Corominas H. Clinical Patterns and Follow-Up of Inflammatory Arthritis and Other Immune-Related Adverse Events Induced by Checkpoint Inhibitors. A Multicenter Study. Frontiers in Medicine. 2022; 9:888377. DOI:10.3389/fmed.2022.888377. PMID:35783644. IF:3,9 (Q2/4D). Document type: Article.
Hemmig AK, Gozzoli D, Werlen L, Ewald H, Aschwanden M, Blockmans D, Brouwer E, Buchanan RRC, Camellino D, Campochiaro C, Cimmino MA, Corominas H, Gloy V, Henckaerts L, Kyburz D, Moya P, Owen CE, Stegert M, Tomelleri A, van Y, Yamashita H, Imfeld S, Berger CT, Hemkens LG, Daikeler T. Subclinical giant cell arteritis in new onset polymyalgia rheumatica A systematic review and meta-analysis of individual patient data. SEMINARS IN ARTHRITIS AND RHEUMATISM. 2022; 55:152017. DOI:10.1016/j.semarthrit.2022.152017. PMID:35537222. IF:5 (Q2/3D). Document type: Review.
Hernández B, Rosas J, Díaz C, Belzunegui J, García R, Inciarte J, Pons A, Millán AM, Jeria S, Valero JA, García N, Valero C, Llorente I, Calvo A, Díaz S, Núñez M. Real-World Treatment Patterns and Clinical Outcomes of Baricitinib in Rheumatoid Arthritis Patients in Spain: Results of a Multicenter, Observational Study in Routine Clinical Practice (The ORBIT-RA Study). Rheumatology and Therapy. 2022; 9(2). DOI:10.1007/s40744-021-00423-8. IF:3,8 (Q3/6D). Document type: Article.
Julia A, Gomez A, Lopez M, Blanco F, Erra A, Fernandez A, Mas AJ, Perez C, Vivar MLG, Sanchez S, Alperi M, Sanmarti R, Ortiz AM, Fernandez CM, Diaz C, Moreno E, Li TL, Martinez SH, Absher DM, Myers RM, Molina JT, Marsal S. Longitudinal analysis of blood DNA methylation identifies mechanisms of response to tumor necrosis factor inhibitor therapy in rheumatoid arthritis. 2022; 80:104053. DOI:10.1016/j.ebiom.2022.104053. PMID:35576644. IF:11,1 (Q1/1D). Document type: Article.
Kerick M, Acosta M, Simeón CP, Callejas JL, Assassi S, Carreira P, Castellvi I, Ríos R, Portales RG, Fernández A, García FJ, Aguirre MA, Fernández B, Rodríguez L, de la Peña PG, Vicente E, Andreu JL, de Castro MF, López FJ, Fonollosa V, Guillén A, Tolosa C, Pros A, Beltrán E, Carballeira MR, Narváez FJ, Rivas MR, Ortiz V, Madroñero AB, González MA, Díaz B, Trapiella L, et al., International SSC Group, Australian Scleroderma Interest Group, PRECISESADS Clinical Consortium. Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis. npj Genomic Medicine. 2022; 7(1):57. DOI:10.1038/s41525-022-00327-8. PMID:36198672. IF:5,3 (Q1/2D). Document type: Article.
Kuster S, Jordan S, Elhai M, Held U, Steigmiller K, Bruni C, Cacciapaglia F, Vettori S, Siegert E, Rednic S, Codullo V, Airo P, Braun Y, Hunzelmann N, Joao M, Riccieri V, Gheorghiu A-M, Alegre JJ, Romanowska K, Castellví I, Kötter I, Truchetet M-E, López FJ, Novikov PI, Giollo A, Shirai Y, Belloli L, Zanatta E, Hachulla E, Smith V, Denton C, Ionescu RM, Schmeiser T, Distler JHW, Gabrielli A, Hoffmann A-M, Kuwana M, Allanore Y, Distler O. Effectiveness and safety of tocilizumab in patients with systemic sclerosis: a propensity score matched controlled observational study of the EUSTAR cohort. RMD Open. 2022; 8(2):e002477. DOI:10.1136/rmdopen-2022-002477. PMID:36328401. IF:6,2 (Q1/2D). Document type: Article.
Lopez A, Laiz A, Puig L. Psoriatic arthritis. MEDICINA CLINICA. 2022; 159(1). DOI:10.1016/j.medcli.2022.01.024. PMID:35525675. IF:3,9 (Q2/4D). Document type: Review.
Mariscal A, Zamora C, Diaz C, Ortiz MA, de Agustin JJ, Reina D, Estrada P, Moya P, Corominas H, Vidal S. Increase of Circulating Monocyte-Platelet Conjugates in Rheumatoid Arthritis Responders to IL-6 Blockage. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022; 23(10):5748. DOI:10.3390/ijms23105748. PMID:35628558. IF:5,6 (Q1/3D). Document type: Article.
Marquès M, Correig E, Ibarretxe D, Anoro E, Antonio J, Jericó C, Borrallo RM, Miret M, Näf S, Pardo A, Perea V, Pérez R, Ramírez R, Royuela M, Soler C, Urquizu M, Zamora A, Pedro J, Masana L, Domingo JL, STACOV G. Long-term exposure to PM10 above WHO guidelines exacerbates COVID-19 severity and mortality. ENVIRONMENT INTERNATIONAL. 2022; 158:106930. DOI:10.1016/j.envint.2021.106930. PMID:34678637. IF:11,8 (Q1/1D). Document type: Article.
Martin JL, Sanchez L, Calvo V, Adan A, Hernanz I, Gallego A, Beltran E, Castro S, Fanlo P, Martos AG, Torre I, Cordero M, De Dios JR, Garcia A, Hernandez M, Sanchez A, Garcia A, Maiz O, Miguelez R, Rodriguez S, Urruticoechea A, Veroz R, Conesa A, Fernandez C, Jovani V, Mondejar JJ, Gonzalez OM, Alvarado PM, Romero S, Rubio P, Pena E, Garijo M, Demetrio R, Hernandez JL, Blanco R. Long-term follow-up of certolizumab pegol in uveitis due to immune-mediated inflammatory diseases: multicentre study of 80 patients. RMD Open. 2022; 8(2):e002693. DOI:10.1136/rmdopen-2022-002693. PMID:36597972. IF:6,2 (Q1/2D). Document type: Article.
Masana L, Correig E, Rodriguez C, Anoro E, Arroyo JA, Jerico C, Pedragosa A, la Miret M, Naf S, Pardo A, Perea V, Perez R, Plana N, Ramirez R, Royuela M, Soler C, Urquizu M, Zamora A, Pedro J, STACOV GRP. Effect of statin therapy on SARS-CoV-2 infection-related mortality in hospitalized patients. European Heart Journal-Cardiovascular Pharmacotherapy. 2022; 8(2). DOI:10.1093/ehjcvp/pvaa128. PMID:33135047. IF:7,1 (Q1/1D). Document type: Article.
Mir C, López BM, Pérez BS, Torrent RB, Fernández MIG, Corbeto ML, Gil JG, Zavala RG. Recomendaciones para el diagnóstico y tratamiento de la baja masa ósea para la edad cronológica y la osteoporosis infantil en Atención Primaria. Pediatria De Atencion Primaria. 2022; 24(94). Document type: Article.
Molina M, Castellvi I, Valenzuela C, Ramirez J, Portal J, Franquet T, Narvaez J. Management of progressive pulmonary fibrosis associated with connective tissue disease. Expert Review of Respiratory Medicine. 2022; 16(7). DOI:10.1080/17476348.2022.2107508. PMID:35912842. IF:3,9 (Q2/5D). Document type: Review.
Narváez J, Díaz del Campo Fontecha P, Brito N, Bonilla G, Aburto M, Castellví I, Cano E, Mena N, Nieto MA, Ortiz AM, Valenzuela C, Abad MÁ, Castrejón I, Correyero M, Francisco FM, Hernández MV, Rodríquez JA. SER-SEPAR recommendations for the the management of rheumatoid arthritis-related interstitial lung disease. Part 2: Treatment. Reumatologia Clinica. 2022; 18(9). DOI:10.1016/j.reuma.2022.03.005. PMID:36064885. Document type: Article.
Park HS, Laiz A, del Campo PD, Martinez M, Guerra M, Alonso C, Sanchez J, Corominas H. Prevalence and Risk for Bundle Branch Block, Atrioventricular Block and Pacemaker Implantation in Spondyloarthritis. A Systematic Review of the Literature. Frontiers in Medicine. 2022; 9:851483. DOI:10.3389/fmed.2022.851483. PMID:35402464. IF:3,9 (Q2/4D). Document type: Review.
Pombo M, Sanchez C, Ruiz D, Diaz C, Jovani V, Cea L, Castrejon I. Retention of golimumab treatment following discontinuation of non-TNF inhibitors in patients with inflammatory rheumatic diseases: An analysis of the Spanish BIOBADASER registry. Musculoskeletal Care. 2022; 20(2). DOI:10.1002/msc.1595. PMID:34668303. Document type: Article.
Pou MA, Orfila F, Pagonabarraga J, Ferrer S, Corominas H, Diaz C. Risk of Parkinson’s disease in a gout Mediterranean population: A case-control study. JOINT BONE SPINE. 2022; 89(6):105402. DOI:10.1016/j.jbspin.2022.105402. PMID:35504516. IF:4,2 (Q2/4D). Document type: Article.
Pou MA, Orfila F, Pagonabarraga J, Ferrer S, Corominas H, Diaz C. Le risque de maladie de Parkinson dans une population méditerranéenne de patients goutteux : étude cas-témoins. Revue Du Rhumatisme (edition Francaise). 2022; 89(6). DOI:10.1016/j.rhum.2022.09.019. Document type: Article.
Queiro R, Seoane D, Laiz A, Agirregoikoa EG, Montilla C, Park H-S, Pinto JA, Baute JJB, Ibáñez BJ, Toniolo E, Ramírez J, García AS, Proyecto REAPSER Study G. Characteristics associated with the perception of high-impact disease (PsAID =4) in patients with recent-onset psoriatic arthritis. Machine learning-based model. SEMINARS IN ARTHRITIS AND RHEUMATISM. 2022; 57:152097. DOI:10.1016/j.semarthrit.2022.152097. PMID:36113222. IF:5 (Q2/3D). Document type: Article.
Queiro R, Seoane D, Laiz A, Agirregoikoa EG, Montilla C, Park H-S, Pinto JA, Bethencourt JJ, Ibáñez BJ, Toniolo E, Ramírez J, García AS, Cañete JD, Juanola X, Fiter J, Gratacós J, Rodriguez J, Rosa JN, Martín AL, García AB, Segura PC, Ferrer AL, Barrio SP, Plata AJ, Bustabad S, Guimerá Martín FJ, Capdevilla EF, Díaz RR, Cuervo A, Gibert MA, Larraz PT, de la Morena I, et al., Proyecto REAPSER Study Group. Minimal disease activity (MDA) in patients with recent-onset psoriatic arthritis: predictive model based on machine learning. ARTHRITIS RESEARCH & THERAPY. 2022; 24(1):153. DOI:10.1186/s13075-022-02838-2. PMID:35751091. IF:4,9 (Q2/4D). Document type: Article.
Queiro R, Seoane D, Laiz A, Galindez E, Montilla C, Park HS, Pinto JA, Bethencourt JJ, Joven B, Toniolo E, Ramírez J, Pruenza García C, Proyecto REAPSER Study G. Severe Disease in Patients With Recent-Onset Psoriatic Arthritis. Prediction Model Based on Machine Learning. Frontiers in Medicine. 2022; 9:891863. DOI:10.3389/fmed.2022.891863. PMID:35572968. IF:3,9 (Q2/4D). Document type: Article.
Quilis N, Vela P, Caceres B, Diaz C, Calvo E, Sivera F, Prada A, Ruiz FP, Pascual E, Andres M. Cutaneous adverse events with febuxostat after previous reactions to allopurinol: comment on the article by Singh and Cleveland. ANNALS OF THE RHEUMATIC DISEASES. 2022; 81(7):e124. DOI:10.1136/annrheumdis-2020-218226. PMID:32616605. IF:27,4 (Q1/1D). Document type: Letter.
Riancho JA, Peris P, González J, Pérez JL, Cannata J, Cano A, Carbonell C, Casado E, Ciria M, Corral L, del Pino J, Del Río LM, Díaz M, Díez A, García A, Gómez C, Gómez de Tejada Romero MJ, Guañabens N, Hawkins F, Jódar E, Malouf J, Martínez Díaz G, Monegal A, Muñoz M, Naves M, Nogues X, Nolla JM, Olmos JM, Peris P, Quesada JM, Rodríguez M, Sosa M, Torrijos A, Valero Díaz de Lamadrid C, SEIOMM Osteoporosis Guidelines Writing G. Executive summary clinical practice guideline of postmenopausal, glucocorticoid-induced, and male osteoporosis (2022 update). Revista De Osteoporosis Y Metabolismo Mineral. 2022; 14(1). DOI:10.4321/S1889-836X2022000100002. Document type: Article/Practice guideline.
Rodríguez JA, Brito N, Díaz del Campo Fontecha P, Valenzuela C, Ortiz AM, Nieto MA, Mena N, Cano E, Castellví I, Aburto M, Bonilla G, Hernández MV, Hernández FMF, Correyero M, Castrejón I, Abad MÁ, Narváez J. SER-SEPAR recommendations for the management of rheumatoid arthritis-related interstitial lung disease. Part 1: Epidemiology, risk factors and prognosis. Reumatologia Clinica. 2022; 18(8). DOI:10.1016/j.reuma.2022.02.009. PMID:36085196. Document type: Article.
Sainz L, Riera P, Moya P, Bernal S, Casademont J, Diaz C, Millan AM, Park HS, Lasa A, Corominas H. Role of IL6R Genetic Variants in Predicting Response to Tocilizumab in Patients with Rheumatoid Arthritis. 2022; 14(9):1942. DOI:10.3390/pharmaceutics14091942. PMID:36145690. IF:5,4 (Q1/2D). Document type: Article.
Tornero J, Alperi M, Castellvi I, de Agustin JJ, Escudero A, Garcia R, Gonzalez MA, Hidalgo C, Rubio E, Sanmarti R, Casamira N, Calvo J. Experts document on methotrexate use in combined therapy with biological or targeted synthetic disease modifying drugs in patients with rheumatoid arthritis. Reumatologia Clinica. 2022; 18(1). DOI:10.1016/j.reuma.2020.08.003. PMID:35090610. Document type: Article.
Vilchez F, Martin HB, Garcia E, Corominas H. Not all autoantibodies are clinically relevant. Classic and novel autoantibodies in Sjogren’s syndrome: A critical review. Frontiers in Immunology. 2022; 13:1003054. DOI:10.3389/fimmu.2022.1003054. PMID:36325321. IF:7,3 (Q1/3D). Document type: Review.
Zozaya N, Abdalla F, Zamora SA, Filgueiras JB, Carrillo JMC, Sanchez OD, Sinisterra FD, Garcia A, Pinto PH, Manfredi A, Olmos JM, Luna PMD, Puig L, Ros S, HIdalgo A. Assessing the value contribution of bimekizumab for the treatment of moderate-to-severe psoriasis using a multidisciplinary reflective multi-criteria decision analysis. Expert Review of Pharmacoeconomics & Outcomes Research. 2022; 22(6). DOI:10.1080/14737167.2022.2063842. PMID:35404728. IF:2,3 (Q3/7D). Document type: Article.
Zozaya N, Arrizubieta MI, Bollo E, Castellví I, Espín J, Ortego N, Poveda JL, Rodríguez JA, Rivero A, Marcos JA, Verde L. A multi-criteria decision analysis on the value of nintedanib for interstitial lung diseases. INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE. 2022; 38(1):e64. DOI:10.1017/S0266462322000459. PMID:35912833. IF:3,2 (Q2/5D). Document type: Article.
Zozaya N, Villoro R, Abdalla F, Alfonso S, Balea J, Carrascosa JM, Delgado O, Dolz F, Garcia A, Herranz P, Manfredi A, Martinez J, Morales De los Rios Luna P, Puig L, Ros S, Hildago A. Unmet Needs in the Management of Moderate-to-Severe Psoriasis in Spain: A Multidimensional Evaluation. ACTA DERMATO-VENEREOLOGICA. 2022; 102:adv00678. DOI:10.2340/actadv.v102.583. PMID:35312022. IF:3,6 (Q1/3D). Document type: Article.

Publicaciones 2021

Alegre JJ, Juanola X, Rodriguez JM, Manero J, Villa I, Laiz A, Arteaga MJ, Cea L, Gonzalez CM. Effectiveness and persistence of golimumab as a second biological drug in patients with spondyloarthritis A retrospective study. MEDICINE. 2021; 100(13):e25223. DOI:10.1097/MD.0000000000025223. PMID:33787605. IF:1,817.
Almirall M, Martínez SH, Alegre C, Collado A, Ojeda B, Arias A, Calandre EP, Hidalgo J, Carrillo MD, Huguet R, Tornero J, Alperi M, Fernández B, Julià A, Marsal S, Arranz LI, Blanco F, Pérez C, Olivè A, Corominas H, Martínez V, González I, Erra A, López M, Sanchez S, Fernández A, Gisbert J, Domènech E, Ferrándiz C, Cañete JD, IMIDC Project Collaborative G. Dietary habits in patients with fibromyalgia: A cross-sectional study. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2021; 39(3). PMID:34161227. IF:4,862.
Alserawan L, Penacoba P, Echevarria S, Castillo D, Ortiz E, Martinez L, Naranjo EM, Domingo P, Castellvi I, Juarez C, Mariscal A. Growth Differentiation Factor 15 (GDF-15): A Novel Biomarker Associated with Poorer Respiratory Function in COVID-19. Diagnostics. 2021; 11(11):1998. DOI:10.3390/diagnostics11111998. PMID:34829345. IF:3,992.
Arroyo JA, Julve J, Vlacho B, Corcoy R, Ponte P, Roman E, Navas E, Llaurado G, Franch J, Domingo P, Mauricio D. Previous Vitamin D Supplementation and Morbidity and Mortality Outcomes in People Hospitalised for COVID19: A Cross-Sectional Study. Frontiers in Public Health. 2021; 9:758347. DOI:10.3389/fpubh.2021.758347. PMID:34631653. IF:6,461.
Barcelo M, Torres OH, Mascaro J, Casademont J. Hip fracture and mortality: study of specific causes of death and risk factors. Archives of Osteoporosis. 2021; 16(1):15. DOI:10.1007/s11657-020-00873-7. PMID:33452949. IF:2,879.
Cabrera J, Henriquez MS, Diaz M, Molini PS, Garcia FA, Montoya MJ, Filgueira J, Olmos JM, Coco MB, Castrillon JLP, Hernandez N, Tirado R. Profile of patients who visit medical internists for an osteoporosis assessment: The OSTEOMED registry. REVISTA CLINICA ESPANOLA. 2021; 221(1). DOI:10.1016/j.rce.2020.06.004. PMID:32682689. IF:3,064.
Cai K, Fuller A, Zhang YL, Hensey O, Grossberg D, Christensen R, Shea B, Singh JA, McCarthy GM, Rosenthal AK, Filippou G, Taylor WJ, Diaz C, Stamp LK, Edwards NL, Pascart T, Becce F, Nielsen SM, Tugwell P, Beaton D, Abhishek A, Tedeschi SK, Dalbeth N. Towards development of core domain sets for short term and long term studies of calcium pyrophosphate crystal deposition (CPPD) disease: A framework paper by the OMERACT CPPD working group. SEMINARS IN ARTHRITIS AND RHEUMATISM. 2021; 51(4). DOI:10.1016/j.semarthrit.2021.04.019. PMID:34140183. IF:5,431.
Castillo D, Barril S, Rodrigo A, Millan P, Suarez G, Alonso A, Franquet T, Lopez L, Castellvi I, Plaza V, Sibila O. EARLY HOSPITAL READMISSION INCREASES SHORT AND LONG – TERM MORTALITY IN PATIENTS WITH INTERSTITIAL LUNG DISEASE. SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES. 2021; 38(2):e2021021. DOI:10.36141/svdld.v38i2.10709. PMID:34316260. IF:1,803.
Corominas H, Castellvi I, Diaz C, Matas L, de la Rosa D, Mangues MA, Moya P, Pomar V, Benito N, Moga E, Hernandez N, Casademont J, Domingo P. Sarilumab (IL-6R antagonist) in critically ill patients with cytokine release syndrome by SARS-CoV2. MEDICINE. 2021; 100(19):e25923. DOI:10.1097/MD.0000000000025923. PMID:34106658. IF:1,817.
Corominas H, Castellvi I, Pomar V, Antonijoan R, Mur I, Matas L, Gich I, de Benito N, Laiz A, Castillo D, Villamarin L, Filella D, Mill AM, Quijada MA, Puig M, Casademont J, Domingo P. Effectiveness and safety of intravenous tocilizumab to treat COVID-19-associated hyperinflammatory syndrome: Covizumab-6 observational cohort. CLINICAL IMMUNOLOGY. 2021; 223:108631. DOI:10.1016/j.clim.2020.108631. PMID:33189888. IF:10,190.
Diaz C, Ortiz MA, Garcia A, Jeria S, Sainz L, Fernandez S, Corominas H, Vidal S. The inflammatory role of silent urate crystal deposition in intercritical gout. RHEUMATOLOGY. 2021; 60(11). DOI:10.1093/rheumatology/keab335. PMID:33839783. IF:7,046.
Díaz SM, Sánchez C, Fernández M, Andreu JL, Martínez V, Olivé A, Rosas J, Menor R, García Á, López FJ, Manrique S, García JA, López R, Narváez J, Galisteo C, González J, Naranjo A, Illera Ó, Moreira B, Raya E, Rodríguez M, Júdez E, Moriano C, Torrente V, García B, Guillén C, Castellvi I, Bohórquez C, Loricera J, Belzunegui J, Carreira PE, Sjogrenser G, Spanish Society of Rheumatology Systemic Autoimmune Diseases Study Group (. Digestive involvement in primary Sjögren’s syndrome: Analysis from the Sjögrenser registry. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2021; 38(4). PMID:33025900. IF:4,862.
Domingo P, Pomar V, Mur I, Castellvi I, Corominas H, de Benito N. Not all COVID-19 pandemic waves are alike. CLINICAL MICROBIOLOGY AND INFECTION. 2021; 27(7). DOI:10.1016/j.cmi.2021.04.005. PMID:33887469. IF:13,310.
Fuller A, Cai K, Diaz C, Filippou G, Pascart T, Hensey O, Grossberg D, Christensen R, Shea B, Singh JA, Tedeschi SK, Dalbeth N, Abhishek A. Outcome domains reported by patients, caregivers, healthcare professionals and stakeholders for calcium pyrophosphate deposition (CPPD): A content analysis based on semi-structured qualitative interviews from the OMERACT CPPD working group. SEMINARS IN ARTHRITIS AND RHEUMATISM. 2021; 51(3). DOI:10.1016/j.semarthrit.2020.09.021. PMID:33461759. IF:5,431.
Fuller A, Cai K, Filippou G, Pascart T, Diaz C, Hensey O, Grossberg D, Christensen R, Shea B, Singh JA, Tedeschi SK, Dalbeth N, Abhishek A. Experience and impact of crystal pyrophosphate deposition (CPPD) from a patient and caregiver perspective: A qualitative exploration from the OMERACT CPPD working group. SEMINARS IN ARTHRITIS AND RHEUMATISM. 2021; 51(3). DOI:10.1016/j.semarthrit.2021.04.010. PMID:33941385. IF:5,431.
Garin N, Sole N, Lucas B, Matas L, Moras D, Rodrigo A, Gras L, Fonts N. Drug related problems in clinical practice: a cross-sectional study on their prevalence, risk factors and associated pharmaceutical interventions. Scientific Reports. 2021; 11(1):883. DOI:10.1038/s41598-020-80560-2. PMID:33441854. IF:4,996.
Gomis M, Perez SM, Minguell ER, Loidi VB, Lopez LL, Abarca SR, Tugas EG, Mas N, Bafalluy M. Mobile Health to Improve Adherence and Patient Experience in Heart Transplantation Recipients: The mHeart Trial. Healthcare. 2021; 9(4):463. DOI:10.3390/healthcare9040463. PMID:33919899. IF:3,160.
Julia A, Lopez M, Blanco F, Gomez A, Haro I, Mas AJ, Erra A, Vivar MLG, Monfort J, Sanchez S, Gonzalez I, Alperi M, Castellanos R, Fernandez A, Diaz C, Palau N, Lastra R, Llados J, Sanmarti R, Marsal S. Interactions between rheumatoid arthritis antibodies are associated with the response to anti-tumor necrosis factor therapy. BMC MUSCULOSKELETAL DISORDERS. 2021; 22(1):372. DOI:10.1186/s12891-021-04248-y. PMID:33882889. IF:2,562.
Julia A, Martinez SH, Domenech E, Canete JD, Ferrandiz C, Tornero J, Gisbert JP, Fernandez A, Dauden E, Barreiro M, Perez C, Queiro R, Lopez FJ, Carazo JLS, Mendoza JL, Alperi M, Montilla C, Venegas JJP, Munoz F, Castaneda S, Lasanta ML, Marsal S, Fonseca E, Rodriguez J, Carreira P, Garcia V, Pinto JA, Puig L, Ricart E, Blanco F, Gratacos J, et al. [Garcia E, Diaz C]. Food groups associated with immune-mediated inflammatory diseases: a Mendelian randomization and disease severity study. EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2021; 75(9). DOI:10.1038/s41430-021-00913-6. PMID:33893449. IF:4,884.
Lobo D, Corominas H, Pomar V. Suitability of serology tests for the diagnosis of Lyme disease. Single center urban cohort. MEDICINA CLINICA. 2021; 157(8). DOI:10.1016/j.medcli.2020.08.010. PMID:33279209. IF:3,200.
Magallares B, Lobo D, Castellvi I, Moya P, Gich I, Martinez L, Park H, Millan AM, Laiz A, Diaz C, Fernandez S, Corominas H. Assessment of EULAR/ACR-2019, SLICC-2012 and ACR-1997 Classification Criteria in SLE with Longstanding Disease. Journal of Clinical Medicine. 2021; 10(11):2377. DOI:10.3390/jcm10112377. PMID:34071275. IF:4,964.
Maher TM, Mayes MD, Kreuter M, Volkmann ER, Aringer M, Castellvi I, Cutolo M, Stock C, Schoof N, Alves M, Raghu G, SENSCIS I. Effect of Nintedanib on Lung Function in Patients With Systemic Sclerosis-Associated Interstitial Lung Disease: Further Analyses of a Randomized, Double-Blind, Placebo-Controlled Trial. Arthritis & Rheumatology. 2021; 73(4). DOI:10.1002/art.41576. PMID:33142016. IF:15,483.
Mariscal A, Milan M, Baucells A, Martinez MA, Guillen AG, Trallero E, Alvarado M, Martinez L, Alserawan L, Franco T, Sanz MT, Vinas L, Corominas H, Juarez C, Castellvi I, Selva A. Anti-TIF-1 gamma Antibody Detection Using a Commercial Kit vs In-House Immunoblot: Usefulness in Clinical Practice. Frontiers in Immunology. 2021; 11:625896. DOI:10.3389/fimmu.2020.625896. PMID:33613568. IF:8,786.
Mariscal A, Zamora C, Magallares B, Salman TC, Ortiz MA, Diaz C, Castellvi I, Corominas H, Vidal S. Phenotypic and Functional Consequences of PLT Binding to Monocytes and Its Association with Clinical Features in SLE. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021; 22(9):4719. DOI:10.3390/ijms22094719. PMID:33947017. IF:6,208.
Marron SE, Gomez M, Aragones LT, Goni A, Vilarrasa E, Diaz RM, Garcia FJ, Campos R, Fuentelsaz V, Gilaberte Y, Gracia T, Morales AM, Ros S, Madrid MB, Puig L. Quality of Life in Hidradenitis Suppurativa: Validation of the HSQoL-24. ACTA DERMATO-VENEREOLOGICA. 2021; 101:adv00529. DOI:10.2340/00015555-3905. PMID:34427316. IF:3,875.
Marsal S, Corominas H, de Agustin JJ, Perez C, Lopez M, Borrell H, Reina D, Sanmarti R, Narvaez J, Franco C, Peterfy C, Narvaez JA, Sharma V, Alataris K, Genovese MC, Baker MC. Non-invasive vagus nerve stimulation for rheumatoid arthritis: a proof-of-concept study. Lancet Rheumatology. 2021; 3(4). DOI:10.1016/S2665-9913(20)30425-2. IF:35,482.
Masana L, Correig E, Ibarretxe D, Anoro E, Arroyo JA, Jerico C, Guerrero C, la Miret M, Naf S, Pardo A, Perea V, Perez R, Plana N, Ramirez R, Royuela M, Soler C, Urquizu M, Zamora A, Pedro J. Low HDL and high triglycerides predict COVID-19 severity. Scientific Reports. 2021; 11(1):7217. DOI:10.1038/s41598-021-86747-5. PMID:33785815. IF:4,996.
Morillon MB, Christensen R, Singh JA, Dalbeth N, Saag K, Taylor WJ, Neogi T, Kennedy MA, Pedersen BM, McCarthy GM, Shea B, Diaz C, Tedeschi SK, Grainger R, Abhishek A, Gaffo A, Nielsen SM, Noerup A, Simon LS, Lassere M, Tugwell P, Stamp LK, Gout Working Group FTO. Serum urate as a proposed surrogate outcome measure in gout trials: From the OMERACT working group. SEMINARS IN ARTHRITIS AND RHEUMATISM. 2021; 51(6). DOI:10.1016/j.semarthrit.2021.11.004. PMID:34839932. IF:5,431.
Mostaza JM, Suarez C, Cepeda JM, Manzano L, Sanchez D, Mascaró J, Maestre A. Demographic, clinical, and functional determinants of antithrombotic treatment in patients with nonvalvular atrial fibrillation. BMC Cardiovascular Disorders. 2021; 21(1):384. DOI:10.1186/s12872-021-02019-0. PMID:34372782. IF:2,174.
Moya P, Leon AF, Corica ME, Marti VC, Lopez DA, Castellvi I, Corominas H. «The added value of 18f-FDG PET/CT in the assessment of onset and steroid resistant polimyalgia rheumatica». PLoS One. 2021; 16(9):e0255131. DOI:10.1371/journal.pone.0255131. PMID:34559822. IF:3,752.
Murillo JD, Diaz C, Ortiz MA, Coras R, Gil P, Pedersen A, Corominas H, Vidal S, Guma M. Metabolomics profiling predicts outcome of tocilizumab in rheumatoid arthritis: an exploratory study. Metabolomics. 2021; 17(9):74. DOI:10.1007/s11306-021-01822-2. PMID:34402961. IF:4,747.
Park HS, Laiz A, Sanchez J, del Campo PD, Martin MA, Guerra M, Corominas H. Valve Abnormalities, Risk Factors for Heart Valve Disease and Valve Replacement Surgery in Spondyloarthritis. A Systematic Review of the Literature. Frontiers in Cardiovascular Medicine. 2021; 8:719523. DOI:10.3389/fcvm.2021.719523. PMID:34631824. IF:5,846.
Prieto D, Bernabeu P, Vela P, Narvaez J, Fernandez JC, Freire M, Gonzalez B, Solans R, Rubio JLC, Ortego N, Fernandez C, Rubio E, Garcia S, Minguez M, Fernandez C, de Miguel E, Melchor S, Salgado E, Bravo B, Romero S, Salvatierra J, Hidalgo C, Manrique S, Romero C, Moya P, Alvarez N, Mendizabal J, Ortiz F, de Pedro IP, Alonso JL, Perez L, et al. Tocilizumab in refractory Caucasian Takayasu’s arteritis: a multicenter study of 54 patients and literature review. Therapeutic Advances in Musculoskeletal Disease. 2021; 13:1759720X211020917. DOI:10.1177/1759720X211020917. PMID:34211589. IF:3,625.
Prior A, Sanchez C, Campos J, Manero FJ, Perez C, Bohorquez C, Busquets N, Blanco JM, Diaz C, Sanchez F, Mateo L, Holgado S. Clinical factors associated with discontinuation of ts/bDMARDs in rheumatic patients from the BIOBADASER III registry. Scientific Reports. 2021; 11(1):11091. DOI:10.1038/s41598-021-90442-w. PMID:34045525. IF:4,996.
Riancho L, Martinez V, Rua I, Alonso F, Galindo M, Ovalles J, Olive A, Vazquez NM, Calvo J, Menor R, Tomero E, Uriarte E, Botenau A, Andres M, Freire M, Soler GS, Ruiz E, Ibanez M, Castellvi I, Galisteo C, Vila VQ, Raya E, Narvaez J, Exposito L, Hernandez JA, Horcada L, Aurrecoechea E, Pego JM. Do all antiphospholipid antibodies confer the same risk for major organ involvement in systemic lupus erythematosus patients?. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2021; 39(3). PMID:32828148. IF:4,862.
Sebastiani M, Luppi F, Sambataro G, Villegas DC, Cerri S, Tomietto P, Cassone G, Bocchino M, Atienza B, Cameli P, Alvarado PM, Faverio P, Bargagli E, Vancheri C, Gonzalez MA, Clini E, Salvarani C, Manfredi A. Interstitial Lung Disease and Anti-Myeloperoxidase Antibodies: Not a Simple Association. Journal of Clinical Medicine. 2021; 10(12):2548. DOI:10.3390/jcm10122548. PMID:34207641. IF:4,964.
Valero JA, Lopez R, Martin MA, Garcia C, Sanchez F, Sanchez JT, Gonzalez C, Revuelta E, Diaz C, Fernandez C, Perez C, Torrente V, Sanchez G, Perez T, Font P, Garcia ML, Aurrecoechea E, Maiz O, Valls R, Miranda JA, Llorca J, Castaneda S, Gonzalez MA, CARMA GRP. Body Mass Index and Disease Activity in Chronic Inflammatory Rheumatic Diseases: Results of the Cardiovascular in Rheumatology (Carma) Project. Journal of Clinical Medicine. 2021; 10(3):382. DOI:10.3390/jcm10030382. PMID:33498379. IF:4,964.

2017 Scientific Report – Multi-organ Damage

Presentación

Principales líneas de investigación

Metabolismo óseo y osteoporosis

Análisis de la influencia genética sobre la osteoporosis mediante estudios de agregación de familias de 3 o más generaciones con un mínimo de 15 miembros.
Estudio de la estructura ósea con TC cuantitativa de la cadera y la columna vertebral, análisis de la contribución de los componentes trabecular y cortical mediante TCAR.
Descripción de los valles y los porcentajes de grasa en una población normal.
Análisis de la influencia del ejercicio físico en cambios en el compartimento muscular de pacientes con cirrosis medido con DXA y HRQCT (en colaboración con el Departamento gastroenterológica).
Descripción de la estructura ósea en pacientes con historia de acromegalia evaluada con DCA y HRQCT.

Hipertensión y riesgo vascular

Hipertensión y calidad de vida.
Hipertensión refractaria.
Uso de alirocumab en hipercolesterolemia.

Gestión clínica, medicina interna y geriatría

Índice de calidad asistencial (mortalidad, readmisiones, etc.).
Medicina perioperatoria.
Prescripción potencialmente inapropiada en pacientes mayores ingresados en el hospital.

Reumatología y artritis reumatoide

Artritis reumatoide precoz
Biomarcadores de artritis reumatoide
Neumopatía intersticial asociada a la artritis reumatoide

Esclerosis sistémica

Patrón y correlación de capilaroscopia con autoanticuerpos y tests de función pulmonar.
Detección de hipertensión arterial pulmonar en esclerosis sistémica basada en la evidencia: estudio DETECT.
Uso de antagonismo por los receptores de la endotelina para prevenir hipertensión arterial pulmonar (en colaboración con el Hospital Universitario del Valle de Hebrón).
Estudios genéticos de esclerosis sistémica y colaboración con Registro DUO y estudio LAUDOS.
Estudio del patrón de capilaroscopia en conectivopatías difusas: estudio QuantiCAP.

Gota

Epidemiología de la hiperuricemia y gota.

Síndrome de Sjögren

Hallazgos clínicos y epidemiológicos en pacientes españoles con síndrome de Sjögren primario (en colaboración con la Sociedad Española de Reumatología).

Retos

Establecer relaciones laborales estables entre los Grupos de Metabolismo Óseo y de Genómica de las Enfermedades Complejas del Hospital de la Santa Creu i Sant Pau y la Unidad de Metabolismo Óseo del Hospital del Mar – Instituto Municipal de Investigación Biomédica y la Facultad de Biología de la Universidad de Barcelona.
Fortalecer los lazos entre los departamentos de reumatología e inmunología en relación al estudio de enfermedades inmunológicas.

Equipo

Coordinación del grupo

COROMINAS MACIAS, HECTOR FGS
hcorominas@santpau.cat

Miembros

Producción científica

Publicaciones 2022

(JIF 2022)

Alvarado PM, de Oro JJD, Espinar MA, Perez EA, Perez NB, Carmona L, Burgos EC, Poch TC, Aguilera AC, Mendieta ED, Alarcon PE, Casares EG, Perez SH, Lopez BM, Morillo MM, Soria LM, Pastor CM, Martinez MM, Fernandez AP, Busquets MP, Garcia JR, Sanz DR, Lizarzaburu MS, Santo Panero P, Alierta ES, Roc MV, Macias HC. Interobserver reliability of Masei index validation by a multicenter collaborative group of rheumatologists. RHEUMATOLOGY INTERNATIONAL. 2022; 42(3). DOI:10.1007/s00296-020-04733-y. PMID:33146762. IF:4 (Q2/5D). Document type: Article.
Balius R, Pujol M, Perez D, Morros C, Susin A, Corominas H, Sala X. Sciatic nerve movement in the deep gluteal space during hip rotations maneuvers. CLINICAL ANATOMY. 2022; 35(4). DOI:10.1002/ca.23828. PMID:34913517. IF:2,4 (Q2/4D). Document type: Article.
Balsa A, González I, Sanmartí R, Corominas H. How do Spanish Rheumatologists handle remission? Survey of knowledge and approach before and after a training workshop. Reumatologia Clinica. 2022; 18(9). DOI:10.1016/j.reuma.2021.08.002, DOI (English Edition):10.1016/j.reumae.2021.08.002. PMID:34489191. Document type: Letter.
Calabria M, Garcia C, Grunden N, Pons C, Arroyo JA, Gomez B, Garcia M, Belvis R, Morollon N, Igual JV, Mur I, Pomar V, Domingo P. Post-COVID-19 fatigue: the contribution of cognitive and neuropsychiatric symptoms. JOURNAL OF NEUROLOGY. 2022; 269(8). DOI:10.1007/s00415-022-11141-8. PMID:35488918. IF:6 (Q1/2D). Document type: Article.
Calvo J, Pou J. Continuing medical education. An opportunity to continue improving. MEDICINA CLINICA. 2022; 159(1). DOI:10.1016/j.medcli.2022.03.012. PMID:35636993. IF:3,9 (Q2/4D). Document type: Editorial material.
Castellvi I, Castillo D, Corominas H, Mariscal A, Orozco S, Benito N, Pomar V, Baucells A, Mur I, de la Rosa D, Lobo D, Millan AM, de Sosa NH, Filella D, Matas L, Martinez L, Juarez C, Casademont J, Domingo P. Krebs von den Lungen-6 glycoprotein circulating levels are not useful as prognostic marker in COVID-19 pneumonia: A large prospective cohort study. Frontiers in Medicine. 2022; 9:973918. DOI:10.3389/fmed.2022.973918. PMID:36004366. IF:3,9 (Q2/4D). Document type: Article.
Castellví I, Vidal S, Valenzuela C. Autoimmunity in the Study of Interstitial Lung Disease: Are Serological Test Enough?. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(8). DOI:10.1016/j.arbres.2021.08.016. PMID:35312568. IF:8 (Q1/2D). Document type: Editorial material.
Cendon L, Rafecas A, De La Rosa D, Castellví I, Spagnolo P, Castillo D. Systematic Review of Systemic Corticosteroids for Treatment of Organizing Pneumonia. Open Respiratory Archives. 2022; 4(4):100211. DOI:10.1016/j.opresp.2022.100211. Document type: Article.
Cobo T, Sánchez C, Nuño L, Castellví I, Carrión I, Romero F, Narváez J, Trallero E, Tomero E, Ruiz ME, Larena C, Carrasco C, Jovaní V, Barbadillo C, Sivera F, Belzunegui J, Pérez A, Gómez A, Delgado E, Pego JM, Joven B, Ibáñez M, Martínez O, Ruiz A, Camins J, Ortega R, Trenor P, Rodríguez M, Freire M, Alcocer P, Holgado S, Rúa I, Lozano N, Martínez J. Myo-Spain: Spanish Registry of Patients with Idiopathic Inflammatory Myopathy. Methodology. Reumatologia Clinica. 2022; 18(5). DOI:10.1016/j.reuma.2021.01.007. PMID:33867271. Document type: Article.
de la Calle C, Rodriguez J, Ciudad L, Ramirez J, Celis R, Azuaga AB, Cuervo A, Graell E, Perez C, Diaz C, Salvador G, Gomez JA, Haro I, Sanmarti R, Canete JD, Ballestar E. The synovial and blood monocyte DNA methylomes mirror prognosis, evolution, and treatment in early arthritis. JCI Insight. 2022; 7(9):e158783. DOI:10.1172/jci.insight.158783. PMID:35324478. IF:8 (Q1/2D). Document type: Article.
De Miguel E, Sanchez JT, Estrada P, Munoz A, Martinez CV, Alvarado PM, Garcia MJ, Angeles V, Da CGL, Frutos AR, Ivorra J, Arrabal SL, Rocha MV, Iniguez CL, Garcia M, Molina C, Villar MA, Mas AJ, Gonzalez MA, Blanco R. Influence of the EULAR recommendations for the use of imaging in large vessel vasculitis in the diagnosis of giant cell arteritis: results of the ARTESER register. RMD Open. 2022; 8(2):e002507. DOI:10.1136/rmdopen-2022-002507. PMID:36597988. IF:6,2 (Q1/2D). Document type: Article.
Fernández SP, Rodríguez F, Laiz A, Castellví I, Magallares B, Corominas H. Impact of the COVID-19 pandemic on rheumatology nursing consultation. Reumatologia Clinica. 2022; 18(4). DOI:10.1016/j.reuma.2021.02.003. PMID:34088653. Document type: Article.
Franco T, Torres OH, Saez ME, Boera G, Santos Á, Clotet S, Albert D, El Y, Agustí M, Casademont J, Juárez C, Martínez L. Early differentiated CD28(+) CD27(+) T lymphocytes as a biomarker for short and long-term outcomes in older patients with pneumonia. JOURNAL OF LEUKOCYTE BIOLOGY. 2022; 112(5). DOI:10.1002/JLB.5MA0422-370R. PMID:35748037. IF:5,5 (Q2/3D). Document type: Article.
Galindo R, Bou R, Mir C, Martínez S, Magallares B, López M. Effectiveness and safety of bisphosphonates therapy in secondary osteoporosis in children. ANALES DE PEDIATRIA. 2022; 97(3). DOI:10.1016/j.anpedi.2021.09.008. PMID:35915035. IF:2,1 (Q3/6D). Document type: Article.
Garcia C, Calabria M, Grunden N, Pons C, Arroyo JA, Gomez B, Lleo A, Alcolea D, Belvis R, Morollon N, Mur I, Pomar V, Domingo P. Neuropsychological deficits in patients with cognitive complaints after COVID-19. Brain and Behavior. 2022; 12(3):e2508. DOI:10.1002/brb3.2508. PMID:35137561. IF:3,1 (Q2/3D). Document type: Article.
Gomez JA, Lobo D, Perez C, Ponce A, Frade B, Arciniegas A, Ojeda F, Ruiz V, Corominas H. Clinical Patterns and Follow-Up of Inflammatory Arthritis and Other Immune-Related Adverse Events Induced by Checkpoint Inhibitors. A Multicenter Study. Frontiers in Medicine. 2022; 9:888377. DOI:10.3389/fmed.2022.888377. PMID:35783644. IF:3,9 (Q2/4D). Document type: Article.
Hemmig AK, Gozzoli D, Werlen L, Ewald H, Aschwanden M, Blockmans D, Brouwer E, Buchanan RRC, Camellino D, Campochiaro C, Cimmino MA, Corominas H, Gloy V, Henckaerts L, Kyburz D, Moya P, Owen CE, Stegert M, Tomelleri A, van Y, Yamashita H, Imfeld S, Berger CT, Hemkens LG, Daikeler T. Subclinical giant cell arteritis in new onset polymyalgia rheumatica A systematic review and meta-analysis of individual patient data. SEMINARS IN ARTHRITIS AND RHEUMATISM. 2022; 55:152017. DOI:10.1016/j.semarthrit.2022.152017. PMID:35537222. IF:5 (Q2/3D). Document type: Review.
Hernández B, Rosas J, Díaz C, Belzunegui J, García R, Inciarte J, Pons A, Millán AM, Jeria S, Valero JA, García N, Valero C, Llorente I, Calvo A, Díaz S, Núñez M. Real-World Treatment Patterns and Clinical Outcomes of Baricitinib in Rheumatoid Arthritis Patients in Spain: Results of a Multicenter, Observational Study in Routine Clinical Practice (The ORBIT-RA Study). Rheumatology and Therapy. 2022; 9(2). DOI:10.1007/s40744-021-00423-8. IF:3,8 (Q3/6D). Document type: Article.
Julia A, Gomez A, Lopez M, Blanco F, Erra A, Fernandez A, Mas AJ, Perez C, Vivar MLG, Sanchez S, Alperi M, Sanmarti R, Ortiz AM, Fernandez CM, Diaz C, Moreno E, Li TL, Martinez SH, Absher DM, Myers RM, Molina JT, Marsal S. Longitudinal analysis of blood DNA methylation identifies mechanisms of response to tumor necrosis factor inhibitor therapy in rheumatoid arthritis. 2022; 80:104053. DOI:10.1016/j.ebiom.2022.104053. PMID:35576644. IF:11,1 (Q1/1D). Document type: Article.
Kerick M, Acosta M, Simeón CP, Callejas JL, Assassi S, Carreira P, Castellvi I, Ríos R, Portales RG, Fernández A, García FJ, Aguirre MA, Fernández B, Rodríguez L, de la Peña PG, Vicente E, Andreu JL, de Castro MF, López FJ, Fonollosa V, Guillén A, Tolosa C, Pros A, Beltrán E, Carballeira MR, Narváez FJ, Rivas MR, Ortiz V, Madroñero AB, González MA, Díaz B, Trapiella L, et al., International SSC Group, Australian Scleroderma Interest Group, PRECISESADS Clinical Consortium. Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis. npj Genomic Medicine. 2022; 7(1):57. DOI:10.1038/s41525-022-00327-8. PMID:36198672. IF:5,3 (Q1/2D). Document type: Article.
Kuster S, Jordan S, Elhai M, Held U, Steigmiller K, Bruni C, Cacciapaglia F, Vettori S, Siegert E, Rednic S, Codullo V, Airo P, Braun Y, Hunzelmann N, Joao M, Riccieri V, Gheorghiu A-M, Alegre JJ, Romanowska K, Castellví I, Kötter I, Truchetet M-E, López FJ, Novikov PI, Giollo A, Shirai Y, Belloli L, Zanatta E, Hachulla E, Smith V, Denton C, Ionescu RM, Schmeiser T, Distler JHW, Gabrielli A, Hoffmann A-M, Kuwana M, Allanore Y, Distler O. Effectiveness and safety of tocilizumab in patients with systemic sclerosis: a propensity score matched controlled observational study of the EUSTAR cohort. RMD Open. 2022; 8(2):e002477. DOI:10.1136/rmdopen-2022-002477. PMID:36328401. IF:6,2 (Q1/2D). Document type: Article.
Lopez A, Laiz A, Puig L. Psoriatic arthritis. MEDICINA CLINICA. 2022; 159(1). DOI:10.1016/j.medcli.2022.01.024. PMID:35525675. IF:3,9 (Q2/4D). Document type: Review.
Mariscal A, Zamora C, Diaz C, Ortiz MA, de Agustin JJ, Reina D, Estrada P, Moya P, Corominas H, Vidal S. Increase of Circulating Monocyte-Platelet Conjugates in Rheumatoid Arthritis Responders to IL-6 Blockage. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022; 23(10):5748. DOI:10.3390/ijms23105748. PMID:35628558. IF:5,6 (Q1/3D). Document type: Article.
Marquès M, Correig E, Ibarretxe D, Anoro E, Antonio J, Jericó C, Borrallo RM, Miret M, Näf S, Pardo A, Perea V, Pérez R, Ramírez R, Royuela M, Soler C, Urquizu M, Zamora A, Pedro J, Masana L, Domingo JL, STACOV G. Long-term exposure to PM10 above WHO guidelines exacerbates COVID-19 severity and mortality. ENVIRONMENT INTERNATIONAL. 2022; 158:106930. DOI:10.1016/j.envint.2021.106930. PMID:34678637. IF:11,8 (Q1/1D). Document type: Article.
Martin JL, Sanchez L, Calvo V, Adan A, Hernanz I, Gallego A, Beltran E, Castro S, Fanlo P, Martos AG, Torre I, Cordero M, De Dios JR, Garcia A, Hernandez M, Sanchez A, Garcia A, Maiz O, Miguelez R, Rodriguez S, Urruticoechea A, Veroz R, Conesa A, Fernandez C, Jovani V, Mondejar JJ, Gonzalez OM, Alvarado PM, Romero S, Rubio P, Pena E, Garijo M, Demetrio R, Hernandez JL, Blanco R. Long-term follow-up of certolizumab pegol in uveitis due to immune-mediated inflammatory diseases: multicentre study of 80 patients. RMD Open. 2022; 8(2):e002693. DOI:10.1136/rmdopen-2022-002693. PMID:36597972. IF:6,2 (Q1/2D). Document type: Article.
Masana L, Correig E, Rodriguez C, Anoro E, Arroyo JA, Jerico C, Pedragosa A, la Miret M, Naf S, Pardo A, Perea V, Perez R, Plana N, Ramirez R, Royuela M, Soler C, Urquizu M, Zamora A, Pedro J, STACOV GRP. Effect of statin therapy on SARS-CoV-2 infection-related mortality in hospitalized patients. European Heart Journal-Cardiovascular Pharmacotherapy. 2022; 8(2). DOI:10.1093/ehjcvp/pvaa128. PMID:33135047. IF:7,1 (Q1/1D). Document type: Article.
Mir C, López BM, Pérez BS, Torrent RB, Fernández MIG, Corbeto ML, Gil JG, Zavala RG. Recomendaciones para el diagnóstico y tratamiento de la baja masa ósea para la edad cronológica y la osteoporosis infantil en Atención Primaria. Pediatria De Atencion Primaria. 2022; 24(94). Document type: Article.
Molina M, Castellvi I, Valenzuela C, Ramirez J, Portal J, Franquet T, Narvaez J. Management of progressive pulmonary fibrosis associated with connective tissue disease. Expert Review of Respiratory Medicine. 2022; 16(7). DOI:10.1080/17476348.2022.2107508. PMID:35912842. IF:3,9 (Q2/5D). Document type: Review.
Narváez J, Díaz del Campo Fontecha P, Brito N, Bonilla G, Aburto M, Castellví I, Cano E, Mena N, Nieto MA, Ortiz AM, Valenzuela C, Abad MÁ, Castrejón I, Correyero M, Francisco FM, Hernández MV, Rodríquez JA. SER-SEPAR recommendations for the the management of rheumatoid arthritis-related interstitial lung disease. Part 2: Treatment. Reumatologia Clinica. 2022; 18(9). DOI:10.1016/j.reuma.2022.03.005. PMID:36064885. Document type: Article.
Park HS, Laiz A, del Campo PD, Martinez M, Guerra M, Alonso C, Sanchez J, Corominas H. Prevalence and Risk for Bundle Branch Block, Atrioventricular Block and Pacemaker Implantation in Spondyloarthritis. A Systematic Review of the Literature. Frontiers in Medicine. 2022; 9:851483. DOI:10.3389/fmed.2022.851483. PMID:35402464. IF:3,9 (Q2/4D). Document type: Review.
Pombo M, Sanchez C, Ruiz D, Diaz C, Jovani V, Cea L, Castrejon I. Retention of golimumab treatment following discontinuation of non-TNF inhibitors in patients with inflammatory rheumatic diseases: An analysis of the Spanish BIOBADASER registry. Musculoskeletal Care. 2022; 20(2). DOI:10.1002/msc.1595. PMID:34668303. Document type: Article.
Pou MA, Orfila F, Pagonabarraga J, Ferrer S, Corominas H, Diaz C. Risk of Parkinson’s disease in a gout Mediterranean population: A case-control study. JOINT BONE SPINE. 2022; 89(6):105402. DOI:10.1016/j.jbspin.2022.105402. PMID:35504516. IF:4,2 (Q2/4D). Document type: Article.
Pou MA, Orfila F, Pagonabarraga J, Ferrer S, Corominas H, Diaz C. Le risque de maladie de Parkinson dans une population méditerranéenne de patients goutteux : étude cas-témoins. Revue Du Rhumatisme (edition Francaise). 2022; 89(6). DOI:10.1016/j.rhum.2022.09.019. Document type: Article.
Queiro R, Seoane D, Laiz A, Agirregoikoa EG, Montilla C, Park H-S, Pinto JA, Baute JJB, Ibáñez BJ, Toniolo E, Ramírez J, García AS, Proyecto REAPSER Study G. Characteristics associated with the perception of high-impact disease (PsAID =4) in patients with recent-onset psoriatic arthritis. Machine learning-based model. SEMINARS IN ARTHRITIS AND RHEUMATISM. 2022; 57:152097. DOI:10.1016/j.semarthrit.2022.152097. PMID:36113222. IF:5 (Q2/3D). Document type: Article.
Queiro R, Seoane D, Laiz A, Agirregoikoa EG, Montilla C, Park H-S, Pinto JA, Bethencourt JJ, Ibáñez BJ, Toniolo E, Ramírez J, García AS, Cañete JD, Juanola X, Fiter J, Gratacós J, Rodriguez J, Rosa JN, Martín AL, García AB, Segura PC, Ferrer AL, Barrio SP, Plata AJ, Bustabad S, Guimerá Martín FJ, Capdevilla EF, Díaz RR, Cuervo A, Gibert MA, Larraz PT, de la Morena I, et al., Proyecto REAPSER Study Group. Minimal disease activity (MDA) in patients with recent-onset psoriatic arthritis: predictive model based on machine learning. ARTHRITIS RESEARCH & THERAPY. 2022; 24(1):153. DOI:10.1186/s13075-022-02838-2. PMID:35751091. IF:4,9 (Q2/4D). Document type: Article.
Queiro R, Seoane D, Laiz A, Galindez E, Montilla C, Park HS, Pinto JA, Bethencourt JJ, Joven B, Toniolo E, Ramírez J, Pruenza García C, Proyecto REAPSER Study G. Severe Disease in Patients With Recent-Onset Psoriatic Arthritis. Prediction Model Based on Machine Learning. Frontiers in Medicine. 2022; 9:891863. DOI:10.3389/fmed.2022.891863. PMID:35572968. IF:3,9 (Q2/4D). Document type: Article.
Quilis N, Vela P, Caceres B, Diaz C, Calvo E, Sivera F, Prada A, Ruiz FP, Pascual E, Andres M. Cutaneous adverse events with febuxostat after previous reactions to allopurinol: comment on the article by Singh and Cleveland. ANNALS OF THE RHEUMATIC DISEASES. 2022; 81(7):e124. DOI:10.1136/annrheumdis-2020-218226. PMID:32616605. IF:27,4 (Q1/1D). Document type: Letter.
Riancho JA, Peris P, González J, Pérez JL, Cannata J, Cano A, Carbonell C, Casado E, Ciria M, Corral L, del Pino J, Del Río LM, Díaz M, Díez A, García A, Gómez C, Gómez de Tejada Romero MJ, Guañabens N, Hawkins F, Jódar E, Malouf J, Martínez Díaz G, Monegal A, Muñoz M, Naves M, Nogues X, Nolla JM, Olmos JM, Peris P, Quesada JM, Rodríguez M, Sosa M, Torrijos A, Valero Díaz de Lamadrid C, SEIOMM Osteoporosis Guidelines Writing G. Executive summary clinical practice guideline of postmenopausal, glucocorticoid-induced, and male osteoporosis (2022 update). Revista De Osteoporosis Y Metabolismo Mineral. 2022; 14(1). DOI:10.4321/S1889-836X2022000100002. Document type: Article/Practice guideline.
Rodríguez JA, Brito N, Díaz del Campo Fontecha P, Valenzuela C, Ortiz AM, Nieto MA, Mena N, Cano E, Castellví I, Aburto M, Bonilla G, Hernández MV, Hernández FMF, Correyero M, Castrejón I, Abad MÁ, Narváez J. SER-SEPAR recommendations for the management of rheumatoid arthritis-related interstitial lung disease. Part 1: Epidemiology, risk factors and prognosis. Reumatologia Clinica. 2022; 18(8). DOI:10.1016/j.reuma.2022.02.009. PMID:36085196. Document type: Article.
Sainz L, Riera P, Moya P, Bernal S, Casademont J, Diaz C, Millan AM, Park HS, Lasa A, Corominas H. Role of IL6R Genetic Variants in Predicting Response to Tocilizumab in Patients with Rheumatoid Arthritis. 2022; 14(9):1942. DOI:10.3390/pharmaceutics14091942. PMID:36145690. IF:5,4 (Q1/2D). Document type: Article.
Tornero J, Alperi M, Castellvi I, de Agustin JJ, Escudero A, Garcia R, Gonzalez MA, Hidalgo C, Rubio E, Sanmarti R, Casamira N, Calvo J. Experts document on methotrexate use in combined therapy with biological or targeted synthetic disease modifying drugs in patients with rheumatoid arthritis. Reumatologia Clinica. 2022; 18(1). DOI:10.1016/j.reuma.2020.08.003. PMID:35090610. Document type: Article.
Vilchez F, Martin HB, Garcia E, Corominas H. Not all autoantibodies are clinically relevant. Classic and novel autoantibodies in Sjogren’s syndrome: A critical review. Frontiers in Immunology. 2022; 13:1003054. DOI:10.3389/fimmu.2022.1003054. PMID:36325321. IF:7,3 (Q1/3D). Document type: Review.
Zozaya N, Abdalla F, Zamora SA, Filgueiras JB, Carrillo JMC, Sanchez OD, Sinisterra FD, Garcia A, Pinto PH, Manfredi A, Olmos JM, Luna PMD, Puig L, Ros S, HIdalgo A. Assessing the value contribution of bimekizumab for the treatment of moderate-to-severe psoriasis using a multidisciplinary reflective multi-criteria decision analysis. Expert Review of Pharmacoeconomics & Outcomes Research. 2022; 22(6). DOI:10.1080/14737167.2022.2063842. PMID:35404728. IF:2,3 (Q3/7D). Document type: Article.
Zozaya N, Arrizubieta MI, Bollo E, Castellví I, Espín J, Ortego N, Poveda JL, Rodríguez JA, Rivero A, Marcos JA, Verde L. A multi-criteria decision analysis on the value of nintedanib for interstitial lung diseases. INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE. 2022; 38(1):e64. DOI:10.1017/S0266462322000459. PMID:35912833. IF:3,2 (Q2/5D). Document type: Article.
Zozaya N, Villoro R, Abdalla F, Alfonso S, Balea J, Carrascosa JM, Delgado O, Dolz F, Garcia A, Herranz P, Manfredi A, Martinez J, Morales De los Rios Luna P, Puig L, Ros S, Hildago A. Unmet Needs in the Management of Moderate-to-Severe Psoriasis in Spain: A Multidimensional Evaluation. ACTA DERMATO-VENEREOLOGICA. 2022; 102:adv00678. DOI:10.2340/actadv.v102.583. PMID:35312022. IF:3,6 (Q1/3D). Document type: Article.

Publicaciones 2021

Alegre JJ, Juanola X, Rodriguez JM, Manero J, Villa I, Laiz A, Arteaga MJ, Cea L, Gonzalez CM. Effectiveness and persistence of golimumab as a second biological drug in patients with spondyloarthritis A retrospective study. MEDICINE. 2021; 100(13):e25223. DOI:10.1097/MD.0000000000025223. PMID:33787605. IF:1,817.
Almirall M, Martínez SH, Alegre C, Collado A, Ojeda B, Arias A, Calandre EP, Hidalgo J, Carrillo MD, Huguet R, Tornero J, Alperi M, Fernández B, Julià A, Marsal S, Arranz LI, Blanco F, Pérez C, Olivè A, Corominas H, Martínez V, González I, Erra A, López M, Sanchez S, Fernández A, Gisbert J, Domènech E, Ferrándiz C, Cañete JD, IMIDC Project Collaborative G. Dietary habits in patients with fibromyalgia: A cross-sectional study. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2021; 39(3). PMID:34161227. IF:4,862.
Alserawan L, Penacoba P, Echevarria S, Castillo D, Ortiz E, Martinez L, Naranjo EM, Domingo P, Castellvi I, Juarez C, Mariscal A. Growth Differentiation Factor 15 (GDF-15): A Novel Biomarker Associated with Poorer Respiratory Function in COVID-19. Diagnostics. 2021; 11(11):1998. DOI:10.3390/diagnostics11111998. PMID:34829345. IF:3,992.
Arroyo JA, Julve J, Vlacho B, Corcoy R, Ponte P, Roman E, Navas E, Llaurado G, Franch J, Domingo P, Mauricio D. Previous Vitamin D Supplementation and Morbidity and Mortality Outcomes in People Hospitalised for COVID19: A Cross-Sectional Study. Frontiers in Public Health. 2021; 9:758347. DOI:10.3389/fpubh.2021.758347. PMID:34631653. IF:6,461.
Barcelo M, Torres OH, Mascaro J, Casademont J. Hip fracture and mortality: study of specific causes of death and risk factors. Archives of Osteoporosis. 2021; 16(1):15. DOI:10.1007/s11657-020-00873-7. PMID:33452949. IF:2,879.
Cabrera J, Henriquez MS, Diaz M, Molini PS, Garcia FA, Montoya MJ, Filgueira J, Olmos JM, Coco MB, Castrillon JLP, Hernandez N, Tirado R. Profile of patients who visit medical internists for an osteoporosis assessment: The OSTEOMED registry. REVISTA CLINICA ESPANOLA. 2021; 221(1). DOI:10.1016/j.rce.2020.06.004. PMID:32682689. IF:3,064.
Cai K, Fuller A, Zhang YL, Hensey O, Grossberg D, Christensen R, Shea B, Singh JA, McCarthy GM, Rosenthal AK, Filippou G, Taylor WJ, Diaz C, Stamp LK, Edwards NL, Pascart T, Becce F, Nielsen SM, Tugwell P, Beaton D, Abhishek A, Tedeschi SK, Dalbeth N. Towards development of core domain sets for short term and long term studies of calcium pyrophosphate crystal deposition (CPPD) disease: A framework paper by the OMERACT CPPD working group. SEMINARS IN ARTHRITIS AND RHEUMATISM. 2021; 51(4). DOI:10.1016/j.semarthrit.2021.04.019. PMID:34140183. IF:5,431.
Castillo D, Barril S, Rodrigo A, Millan P, Suarez G, Alonso A, Franquet T, Lopez L, Castellvi I, Plaza V, Sibila O. EARLY HOSPITAL READMISSION INCREASES SHORT AND LONG – TERM MORTALITY IN PATIENTS WITH INTERSTITIAL LUNG DISEASE. SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES. 2021; 38(2):e2021021. DOI:10.36141/svdld.v38i2.10709. PMID:34316260. IF:1,803.
Corominas H, Castellvi I, Diaz C, Matas L, de la Rosa D, Mangues MA, Moya P, Pomar V, Benito N, Moga E, Hernandez N, Casademont J, Domingo P. Sarilumab (IL-6R antagonist) in critically ill patients with cytokine release syndrome by SARS-CoV2. MEDICINE. 2021; 100(19):e25923. DOI:10.1097/MD.0000000000025923. PMID:34106658. IF:1,817.
Corominas H, Castellvi I, Pomar V, Antonijoan R, Mur I, Matas L, Gich I, de Benito N, Laiz A, Castillo D, Villamarin L, Filella D, Mill AM, Quijada MA, Puig M, Casademont J, Domingo P. Effectiveness and safety of intravenous tocilizumab to treat COVID-19-associated hyperinflammatory syndrome: Covizumab-6 observational cohort. CLINICAL IMMUNOLOGY. 2021; 223:108631. DOI:10.1016/j.clim.2020.108631. PMID:33189888. IF:10,190.
Diaz C, Ortiz MA, Garcia A, Jeria S, Sainz L, Fernandez S, Corominas H, Vidal S. The inflammatory role of silent urate crystal deposition in intercritical gout. RHEUMATOLOGY. 2021; 60(11). DOI:10.1093/rheumatology/keab335. PMID:33839783. IF:7,046.
Díaz SM, Sánchez C, Fernández M, Andreu JL, Martínez V, Olivé A, Rosas J, Menor R, García Á, López FJ, Manrique S, García JA, López R, Narváez J, Galisteo C, González J, Naranjo A, Illera Ó, Moreira B, Raya E, Rodríguez M, Júdez E, Moriano C, Torrente V, García B, Guillén C, Castellvi I, Bohórquez C, Loricera J, Belzunegui J, Carreira PE, Sjogrenser G, Spanish Society of Rheumatology Systemic Autoimmune Diseases Study Group (. Digestive involvement in primary Sjögren’s syndrome: Analysis from the Sjögrenser registry. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2021; 38(4). PMID:33025900. IF:4,862.
Domingo P, Pomar V, Mur I, Castellvi I, Corominas H, de Benito N. Not all COVID-19 pandemic waves are alike. CLINICAL MICROBIOLOGY AND INFECTION. 2021; 27(7). DOI:10.1016/j.cmi.2021.04.005. PMID:33887469. IF:13,310.
Fuller A, Cai K, Diaz C, Filippou G, Pascart T, Hensey O, Grossberg D, Christensen R, Shea B, Singh JA, Tedeschi SK, Dalbeth N, Abhishek A. Outcome domains reported by patients, caregivers, healthcare professionals and stakeholders for calcium pyrophosphate deposition (CPPD): A content analysis based on semi-structured qualitative interviews from the OMERACT CPPD working group. SEMINARS IN ARTHRITIS AND RHEUMATISM. 2021; 51(3). DOI:10.1016/j.semarthrit.2020.09.021. PMID:33461759. IF:5,431.
Fuller A, Cai K, Filippou G, Pascart T, Diaz C, Hensey O, Grossberg D, Christensen R, Shea B, Singh JA, Tedeschi SK, Dalbeth N, Abhishek A. Experience and impact of crystal pyrophosphate deposition (CPPD) from a patient and caregiver perspective: A qualitative exploration from the OMERACT CPPD working group. SEMINARS IN ARTHRITIS AND RHEUMATISM. 2021; 51(3). DOI:10.1016/j.semarthrit.2021.04.010. PMID:33941385. IF:5,431.
Garin N, Sole N, Lucas B, Matas L, Moras D, Rodrigo A, Gras L, Fonts N. Drug related problems in clinical practice: a cross-sectional study on their prevalence, risk factors and associated pharmaceutical interventions. Scientific Reports. 2021; 11(1):883. DOI:10.1038/s41598-020-80560-2. PMID:33441854. IF:4,996.
Gomis M, Perez SM, Minguell ER, Loidi VB, Lopez LL, Abarca SR, Tugas EG, Mas N, Bafalluy M. Mobile Health to Improve Adherence and Patient Experience in Heart Transplantation Recipients: The mHeart Trial. Healthcare. 2021; 9(4):463. DOI:10.3390/healthcare9040463. PMID:33919899. IF:3,160.
Julia A, Lopez M, Blanco F, Gomez A, Haro I, Mas AJ, Erra A, Vivar MLG, Monfort J, Sanchez S, Gonzalez I, Alperi M, Castellanos R, Fernandez A, Diaz C, Palau N, Lastra R, Llados J, Sanmarti R, Marsal S. Interactions between rheumatoid arthritis antibodies are associated with the response to anti-tumor necrosis factor therapy. BMC MUSCULOSKELETAL DISORDERS. 2021; 22(1):372. DOI:10.1186/s12891-021-04248-y. PMID:33882889. IF:2,562.
Julia A, Martinez SH, Domenech E, Canete JD, Ferrandiz C, Tornero J, Gisbert JP, Fernandez A, Dauden E, Barreiro M, Perez C, Queiro R, Lopez FJ, Carazo JLS, Mendoza JL, Alperi M, Montilla C, Venegas JJP, Munoz F, Castaneda S, Lasanta ML, Marsal S, Fonseca E, Rodriguez J, Carreira P, Garcia V, Pinto JA, Puig L, Ricart E, Blanco F, Gratacos J, et al. [Garcia E, Diaz C]. Food groups associated with immune-mediated inflammatory diseases: a Mendelian randomization and disease severity study. EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2021; 75(9). DOI:10.1038/s41430-021-00913-6. PMID:33893449. IF:4,884.
Lobo D, Corominas H, Pomar V. Suitability of serology tests for the diagnosis of Lyme disease. Single center urban cohort. MEDICINA CLINICA. 2021; 157(8). DOI:10.1016/j.medcli.2020.08.010. PMID:33279209. IF:3,200.
Magallares B, Lobo D, Castellvi I, Moya P, Gich I, Martinez L, Park H, Millan AM, Laiz A, Diaz C, Fernandez S, Corominas H. Assessment of EULAR/ACR-2019, SLICC-2012 and ACR-1997 Classification Criteria in SLE with Longstanding Disease. Journal of Clinical Medicine. 2021; 10(11):2377. DOI:10.3390/jcm10112377. PMID:34071275. IF:4,964.
Maher TM, Mayes MD, Kreuter M, Volkmann ER, Aringer M, Castellvi I, Cutolo M, Stock C, Schoof N, Alves M, Raghu G, SENSCIS I. Effect of Nintedanib on Lung Function in Patients With Systemic Sclerosis-Associated Interstitial Lung Disease: Further Analyses of a Randomized, Double-Blind, Placebo-Controlled Trial. Arthritis & Rheumatology. 2021; 73(4). DOI:10.1002/art.41576. PMID:33142016. IF:15,483.
Mariscal A, Milan M, Baucells A, Martinez MA, Guillen AG, Trallero E, Alvarado M, Martinez L, Alserawan L, Franco T, Sanz MT, Vinas L, Corominas H, Juarez C, Castellvi I, Selva A. Anti-TIF-1 gamma Antibody Detection Using a Commercial Kit vs In-House Immunoblot: Usefulness in Clinical Practice. Frontiers in Immunology. 2021; 11:625896. DOI:10.3389/fimmu.2020.625896. PMID:33613568. IF:8,786.
Mariscal A, Zamora C, Magallares B, Salman TC, Ortiz MA, Diaz C, Castellvi I, Corominas H, Vidal S. Phenotypic and Functional Consequences of PLT Binding to Monocytes and Its Association with Clinical Features in SLE. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021; 22(9):4719. DOI:10.3390/ijms22094719. PMID:33947017. IF:6,208.
Marron SE, Gomez M, Aragones LT, Goni A, Vilarrasa E, Diaz RM, Garcia FJ, Campos R, Fuentelsaz V, Gilaberte Y, Gracia T, Morales AM, Ros S, Madrid MB, Puig L. Quality of Life in Hidradenitis Suppurativa: Validation of the HSQoL-24. ACTA DERMATO-VENEREOLOGICA. 2021; 101:adv00529. DOI:10.2340/00015555-3905. PMID:34427316. IF:3,875.
Marsal S, Corominas H, de Agustin JJ, Perez C, Lopez M, Borrell H, Reina D, Sanmarti R, Narvaez J, Franco C, Peterfy C, Narvaez JA, Sharma V, Alataris K, Genovese MC, Baker MC. Non-invasive vagus nerve stimulation for rheumatoid arthritis: a proof-of-concept study. Lancet Rheumatology. 2021; 3(4). DOI:10.1016/S2665-9913(20)30425-2. IF:35,482.
Masana L, Correig E, Ibarretxe D, Anoro E, Arroyo JA, Jerico C, Guerrero C, la Miret M, Naf S, Pardo A, Perea V, Perez R, Plana N, Ramirez R, Royuela M, Soler C, Urquizu M, Zamora A, Pedro J. Low HDL and high triglycerides predict COVID-19 severity. Scientific Reports. 2021; 11(1):7217. DOI:10.1038/s41598-021-86747-5. PMID:33785815. IF:4,996.
Morillon MB, Christensen R, Singh JA, Dalbeth N, Saag K, Taylor WJ, Neogi T, Kennedy MA, Pedersen BM, McCarthy GM, Shea B, Diaz C, Tedeschi SK, Grainger R, Abhishek A, Gaffo A, Nielsen SM, Noerup A, Simon LS, Lassere M, Tugwell P, Stamp LK, Gout Working Group FTO. Serum urate as a proposed surrogate outcome measure in gout trials: From the OMERACT working group. SEMINARS IN ARTHRITIS AND RHEUMATISM. 2021; 51(6). DOI:10.1016/j.semarthrit.2021.11.004. PMID:34839932. IF:5,431.
Mostaza JM, Suarez C, Cepeda JM, Manzano L, Sanchez D, Mascaró J, Maestre A. Demographic, clinical, and functional determinants of antithrombotic treatment in patients with nonvalvular atrial fibrillation. BMC Cardiovascular Disorders. 2021; 21(1):384. DOI:10.1186/s12872-021-02019-0. PMID:34372782. IF:2,174.
Moya P, Leon AF, Corica ME, Marti VC, Lopez DA, Castellvi I, Corominas H. «The added value of 18f-FDG PET/CT in the assessment of onset and steroid resistant polimyalgia rheumatica». PLoS One. 2021; 16(9):e0255131. DOI:10.1371/journal.pone.0255131. PMID:34559822. IF:3,752.
Murillo JD, Diaz C, Ortiz MA, Coras R, Gil P, Pedersen A, Corominas H, Vidal S, Guma M. Metabolomics profiling predicts outcome of tocilizumab in rheumatoid arthritis: an exploratory study. Metabolomics. 2021; 17(9):74. DOI:10.1007/s11306-021-01822-2. PMID:34402961. IF:4,747.
Park HS, Laiz A, Sanchez J, del Campo PD, Martin MA, Guerra M, Corominas H. Valve Abnormalities, Risk Factors for Heart Valve Disease and Valve Replacement Surgery in Spondyloarthritis. A Systematic Review of the Literature. Frontiers in Cardiovascular Medicine. 2021; 8:719523. DOI:10.3389/fcvm.2021.719523. PMID:34631824. IF:5,846.
Prieto D, Bernabeu P, Vela P, Narvaez J, Fernandez JC, Freire M, Gonzalez B, Solans R, Rubio JLC, Ortego N, Fernandez C, Rubio E, Garcia S, Minguez M, Fernandez C, de Miguel E, Melchor S, Salgado E, Bravo B, Romero S, Salvatierra J, Hidalgo C, Manrique S, Romero C, Moya P, Alvarez N, Mendizabal J, Ortiz F, de Pedro IP, Alonso JL, Perez L, et al. Tocilizumab in refractory Caucasian Takayasu’s arteritis: a multicenter study of 54 patients and literature review. Therapeutic Advances in Musculoskeletal Disease. 2021; 13:1759720X211020917. DOI:10.1177/1759720X211020917. PMID:34211589. IF:3,625.
Prior A, Sanchez C, Campos J, Manero FJ, Perez C, Bohorquez C, Busquets N, Blanco JM, Diaz C, Sanchez F, Mateo L, Holgado S. Clinical factors associated with discontinuation of ts/bDMARDs in rheumatic patients from the BIOBADASER III registry. Scientific Reports. 2021; 11(1):11091. DOI:10.1038/s41598-021-90442-w. PMID:34045525. IF:4,996.
Riancho L, Martinez V, Rua I, Alonso F, Galindo M, Ovalles J, Olive A, Vazquez NM, Calvo J, Menor R, Tomero E, Uriarte E, Botenau A, Andres M, Freire M, Soler GS, Ruiz E, Ibanez M, Castellvi I, Galisteo C, Vila VQ, Raya E, Narvaez J, Exposito L, Hernandez JA, Horcada L, Aurrecoechea E, Pego JM. Do all antiphospholipid antibodies confer the same risk for major organ involvement in systemic lupus erythematosus patients?. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2021; 39(3). PMID:32828148. IF:4,862.
Sebastiani M, Luppi F, Sambataro G, Villegas DC, Cerri S, Tomietto P, Cassone G, Bocchino M, Atienza B, Cameli P, Alvarado PM, Faverio P, Bargagli E, Vancheri C, Gonzalez MA, Clini E, Salvarani C, Manfredi A. Interstitial Lung Disease and Anti-Myeloperoxidase Antibodies: Not a Simple Association. Journal of Clinical Medicine. 2021; 10(12):2548. DOI:10.3390/jcm10122548. PMID:34207641. IF:4,964.
Valero JA, Lopez R, Martin MA, Garcia C, Sanchez F, Sanchez JT, Gonzalez C, Revuelta E, Diaz C, Fernandez C, Perez C, Torrente V, Sanchez G, Perez T, Font P, Garcia ML, Aurrecoechea E, Maiz O, Valls R, Miranda JA, Llorca J, Castaneda S, Gonzalez MA, CARMA GRP. Body Mass Index and Disease Activity in Chronic Inflammatory Rheumatic Diseases: Results of the Cardiovascular in Rheumatology (Carma) Project. Journal of Clinical Medicine. 2021; 10(3):382. DOI:10.3390/jcm10030382. PMID:33498379. IF:4,964.

MEDICINA TRANSLACIONAL

Daño multiorgánico y reumatología

Principales líneas de investigación

Metabolismo óseo y osteoporosis

Hipertensión y riesgo vascular

Gestión clínica, medicina interna y geriatría

Reumatología y artritis reumatoide

Esclerosis sistémica

Gota

Síndrome de Sjögren

Retos

Coordinación del grupo

Miembros

Publicaciones 2022

Publicaciones 2021

Principales líneas de investigación

Metabolismo óseo y osteoporosis

Hipertensión y riesgo vascular

Gestión clínica, medicina interna y geriatría

Reumatología y artritis reumatoide

Esclerosis sistémica

Gota

Síndrome de Sjögren

Retos

Coordinación del grupo

Miembros

Publicaciones 2022

Publicaciones 2021

Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau