Sant Pau - Institut de Recerca

Principales líneas de investigación

Investigación experimental

Modelo experimental de rata con cirrosis y ascitis.
Mecanismos de translocación bacteriana en rata con cirrosis y su prevención.
Modelo experimental de peritonitis bacteriana espontánea e inducida: fisiopatología y tratamiento.
Perfil de expresión miRNAs en la enfermedad inflamatoria intestinal después de la estimulación con receptores de ligandos tipo toll.

Investigación clínica

Fisiopatología, diagnóstico, tratamiento y prevención de las infecciones bacterianas, ascitis y síndrome hepatorrenal en la cirrosis.
Diagnóstico y tratamiento de la encefalopatía hepática en la cirrosis.
Discapacidad cognitiva, caídas y calidad de vida en pacientes con cirrosis.
Fisiopatología, diagnóstico, tratamiento y prevención de la hemorragia digestiva por hipertensión portal de origen no varicoso.
La hepatitis crónica B y C: diagnóstico y tratamiento.
Diagnóstico y tratamiento del hepatocarcinoma.
Fisiopatología, diagnóstico y tratamiento de la enfermedad inflamatoria intestinal.
Diagnóstico y tratamiento en endoscopia gastrointestinal avanzada.
Diagnóstico y tratamiento de la pancreatitis aguda.
Prevención de la pancreatitis aguda post-CPRE.
La pancreatitis crónica y las neoplasias de páncreas: estudios moleculares, la detección precoz y el tratamiento.

Retos

Consolidación del grupo de investigación CIBEREHD mediante el estudio de las complicaciones en cirrosis.
Expandir el laboratorio de investigación en hepatología y desarrollar nuevos estudios.
Consolidar el grupo de investigación del portal de hipertensión.
Consolidar la línea de investigación de enfermedad pancreática.
Consolidar la línea de investigación en enfermedad inflamatoria intestinal.
Consolidar la línea de investigación en pólipos y cáncer de colon.
Desarrollar una línea de investigación en endoscopia digestiva.

Coordinación del grupo

ESCORSELL MAÑOSA, Mª ANGELS FGS
MEscorsell@santpau.cat

Miembros

Alvarado Tapias, Edilmar FGS
Bertoletti , Federico FGS
Brujats Rubirola, Anna FGS
Concepcion Martin, Maria Del Mar FGS
Cuyas Espi, Berta FGS
Gallego Moya, Adolfo FGS
Garcia Planella, Esther FGS
Giordano, Antonio IR
Gomez Oliva, Cristina FGS
Gonzalez Muñoza, Carlos FGS
Gordillo Abalos, Jorge FGS
Guarner Argente, Carlos FGS
Guinart Cuadra, Albert IR
Kaur, Naujot FGS
Murzi Pulgar, Marianette Carolina FGS
Oblitas Susanibar, Elida FGS
Poca Sans, Maria FGS
Roig Ramos, Cristina FGS
Roman Abal, Eva Maria FGS
Romero Mascarell, Cristina FGS
Romito, Raffaella FGS
Sainz Saenz-torre, Sergio FGS
Sanchez Ardid, Elisabet CIBEREHD
Soriano Pastor, German FGS
Torras Colell, Javier FGS
Villanueva Sanchez, Candido FGS

Publicaciones 2022

(JIF 2022)

Baiges A, Cerda E, Amicone C, Téllez L, Alvarado E, Puente A, Fortea JI, Llop E, Rocha F, Orts L, Ros O, Vizcarra P, Zekrini K, Lounes OA, Touati G, Jiménez N, Serrano MJ, Falgà A, Magaz M, Olivas P, Betancourt F, Perez V, Turon F, Payancé A, Goria O, Rautou P-E, Hernández V, Villanueva C, Albillos A, Plessier A, García J-C. Impact of SARS-CoV-2 Pandemic on Vascular Liver Diseases. Clinical Gastroenterology and Hepatology. 2022; 20(7). DOI:10.1016/j.cgh.2021.12.032. PMID:34968728. IF:12,6 (Q1/1D). Document type: Article.
Barreiro M, Riestra S, Calafat M, Soto MP, Calvo M, Rodriguez ES, Caballol B, Vela M, Rivero M, Munoz F, de Castro L, Calvet X, Garcia FJ, Fornals AU, Ferreiro R, Gonzalez-Muñoza C, Chaparro M, Bujanda L, Sicilia B, Alfambra E, Rodriguez A, Fernandez RP, Rodriguez C, Almela P, Arguelles F, Busquets D, Tamarit S, Castro CR, Jimenez L, Marin I, Alcaide N, Fernandez E, et al. Management and Long-term Outcomes of Crohn’s Disease Complicated with Enterocutaneous Fistula: ECUFIT Study from GETECCU. Journal of Crohns & Colitis. 2022; 16(7). DOI:10.1093/ecco-jcc/jjac016. PMID:35104314. IF:8 (Q1/2D). Document type: Article.
Bassegoda O, Olivas P, Turco L, Mandorfer M, Serra M, Tellez L, Kwanten W, Laroyenne A, Farcau O, Alvarado E, Moga L, Vuille E, Fortea JI, Ibañez L, Tosetti G, Vanwolleghem T, Larrue H, Burgos D, Stefanescu H, Paternostro R, Cippitelli A, Lens S, Augustin S, Llop E, Laleman W, Trebicka J, Chang J, Masnou H, Zipprich A, Miceli F, Semmler G, Forns X, Primignani M, et al. [Villanueva C]. Decompensation in Advanced Nonalcoholic Fatty Liver Disease May Occur at Lower Hepatic Venous Pressure Gradient Levels Than in Patients With Viral Disease. Clinical Gastroenterology and Hepatology. 2022; 20(10). DOI:10.1016/j.cgh.2021.10.023. PMID:34688952. IF:12,6 (Q1/1D). Document type: Article.
Batista G, Marin I, Fores A, Garcia E, Arguelles F, Tagarro I, Fernandez A, Montoto C, Aparicio J, Aguas M, Santos J, Bosca MM, Ferreiro R, Merino O, Aldeguer X, Corttes X, Sicilia B, Mesonero F, Barreiro M. Treatment patterns and intensification within 5 year of follow-up of the first-line anti-TNF alpha used for the treatment of IBD: Results from the VERNE study. DIGESTIVE AND LIVER DISEASE. 2022; 54(1). DOI:10.1016/j.dld.2021.06.005. PMID:34244110. IF:4,5 (Q2/4D). Document type: Article.
Calafat M, Mañosa M, Ricart E, Nos P, Iglesias E, Vera I, López A, Guardiola J, Taxonera C, Mínguez M, Martín MD, de Castro L, de Francisco R, Rivero M, Garcia E, Calvet X, García S, Márquez L, Gomollón F, Barrio J, Esteve M, Muñoz F, Gisbert JP, Gutiérrez A, Hinojosa J, Argüelles F, Busquets D, Bujanda L, Pérez JL, Sicilia B, Merino O, Martínez P, Bermejo F, Lorente R, Barreiro M, Rodríguez C, García MF, Monfort D, Cañete F, Domènech E. Risk of Immunomediated Adverse Events and Loss of Response to Infliximab in Elderly Patients with Inflammatory Bowel Disease: A Cohort Study of the ENEIDA Registry. Journal of Crohns & Colitis. 2022; 16(6). DOI:10.1093/ecco-jcc/jjab213. PMID:34864947. IF:8 (Q1/2D). Document type: Article.
Casado S, Velasco M, Catala C, Leyton A, Gutierrez R, Suarez B, Armiger N, Carreras E, Esteller M, Ricart E, Ordas I, Gisbert JP, Chaparro M, Esteve M, Marquez L, Busquets D, Iglesias E, Garcia E, Martin MD, Lohmann J, Ayata CK, Niess JH, Engel P, Panes J, Salas A, Domenech E, Lozano F, G. Experimental and genetic evidence for the impact of CD5 and CD6 expression and variation in inflammatory bowel disease. Frontiers in Immunology. 2022; 13:966184. DOI:10.3389/fimmu.2022.966184. PMID:36211446. IF:7,3 (Q1/3D). Document type: Article.
Chaparro M, Baston I, Fernandez E, Garcia JG, Ramos L, Palomares MTDL, Arguelles F, Flores EI, Cabello M, Iturria SR, Ortiz AN, Charro M, Ginard D, Sadornil CD, Ochoa OM, Busquets D, Iyo E, Casbas AG, de la Piscina PR, Bosca MM, Arroyo M, Garcia MJ, Hinojosa E, Gordillo J, Montiel PM, Jimenez BV, Ivorra CQ, Moron JMV, Huguet JM, Gonzalez Y, Santos A, Amo VM, et al. Long-Term Real-World Effectiveness and Safety of Ustekinumab in Crohn’s Disease Patients: The SUSTAIN Study. INFLAMMATORY BOWEL DISEASES. 2022; 28(11). DOI:10.1093/ibd/izab357. PMID:35166347. IF:4,9 (Q2/3D). Document type: Article.
Chaparro M, Baston I, Salgado EF, Garcia JG, Ramos L, Palomares MTDL, Arguelles F, Flores EI, Cabello M, Iturria SR, Ortiz AN, Charro M, Ginard D, Sadornil CD, Ochoa OM, Busquets D, Iyo E, Casbas AG, de la Piscina PR, Bosca MM, Arroyo M, Garcia MJ, Hinojosa E, Gordillo J, Montiel PM, Jimenez BV, Ivorra CQ, Moron JMV, Huguet JM, Gonzalez Y, Santos A, Amo VM, et al. Using Interpretable Machine Learning to Identify Baseline Predictive Factors of Remission and Drug Durability in Crohn’s Disease Patients on Ustekinumab. Journal of Clinical Medicine. 2022; 11(15):4518. DOI:10.3390/jcm11154518. PMID:35956133. IF:3,9 (Q2/4D). Document type: Article.
de Franchis R, Bosch J, Garcia G, Reiberger T, Ripoll C, Abraldes JG, Albillos A, Baiges A, Bajaj J, Bañares R, Barrufet M, Benajiba L, Berzigotti A, Bureau C, Calvaruso V, Cardenas A, D’Amico G, De Gottardi A, Dell’Era A, Escorsell A, Fallowfield J, Ferral H, Francque S, Gaba R, Garcia JC, Genescà J, Rodrigues SG, Gracia J, Han G, Hernandez V, Jia J, Kiladjian JJ, Krag A, et al. [Villanueva C]. Baveno VII – Renewing consensus in portal hypertension. JOURNAL OF HEPATOLOGY. 2022; 76(4). DOI:10.1016/j.jhep.2021.12.022. PMID:35120736. IF:25,7 (Q1/1D). Document type: Review.
de Santiago ER, Aldehuelo RS, Pons FR, Escaja CR, Fernandez G, Canete A, Aracil CF, Perez D, Leon RR, Marcos HM, Delgado PG, Garcia A, Guarner C, Muriel A, de la Fuente E, de Paredes A, Parejo S, Tellez L, Senosiain C, Burgos D, Aicart M, Munoz BM, Penas B, Pagano G, Urquiza GC, Ferreruela MU, de Jorge MA, Barreiro E, Fraile M, Gomez A, Altamirano MI, Esteban MN, Ruiz M, Arribas J, de Frutos D, Herreros A, Arias ML, Roldan M, Martin A, Zamora J, Vazquez E, Albillos A. Endoscopy-Related Bleeding and Thromboembolic Events in Patients on Direct Oral Anticoagulants or Vitamin K Antagonists. Clinical Gastroenterology and Hepatology. 2022; 20(3). DOI:10.1016/j.cgh.2020.11.037. PMID:33279783. IF:12,6 (Q1/1D). Document type: Article.
Gallego-Durán R, Albillos A, Ampuero J, Arechederra M, Bañares R, Blas A, Berná G, Caparrós E, Delgado TC, Falcón JM, Francés R, Fernández MG, Graupera I, Iruzubieta P, Nevzorova YA, Nogueiras R, Macías RIR, Martín F, Sabio G, Soriano G, Vaquero J, Cubero FJ, Gracia J. Metabolic-associated fatty liver disease: From simple steatosis toward liver cirrhosis and potential complications. Proceedings of the Third Translational Hepatology Meeting, organized by the Spanish Association for the Study of the Liver (AEEH). Gastroenterologia y Hepatologia. 2022; 45(9). DOI:10.1016/j.gastrohep.2022.02.005. PMID:35248669. IF:1,9 (Q4/9D). Document type: Review.
Gil A, Rojas A, Garcia MR, Munoz R, Gallego R, Maya D, Montero R, Gato S, Gallego J, Frances R, Soriano G, Ampuero J, Romero M. Impact of a Loss-of-Function Variant in HSD17B13 on Hepatic Decompensation and Mortality in Cirrhotic Patients. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022; 23(19):11840. DOI:10.3390/ijms231911840. PMID:36233142. IF:5,6 (Q1/3D). Document type: Article.
González C, Briones J, Sang H, García E. Marginal zone lymphoma under anti-TNF treatment in Crohn disease. Gastroenterologia y Hepatologia. 2022; 45(5). DOI:10.1016/j.gastrohep.2021.05.010. PMID:34118314. IF:1,9 (Q4/9D). Document type: Letter.
Gonzalez L, Bazaga S, Murzi M, Brujats A, Trias M, de Riba B, Romito R, Colan J, Concepcion M, Gordillo J, Pernas JC, Poca M, Soriano G, Guarner C. Predictors of the need for necrosectomy in patients with walled-off pancreatic necrosis treated with lumen apposition metal stents. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES. 2022; 36(2). DOI:10.1007/s00464-021-08411-3. PMID:33660124. IF:3,1 (Q1/3D). Document type: Article.
Guarner C, Ikematsu H, Osera S, Fraile M, Ibañez B, Marra C, Jerusalén C, Alonso PA, Martinez D, Soto S, Ramos F, Alvarez MA, Rodriguez J, Múgica F, Nogales O, Herreros de Tejada A, Redondo E, Martínez J, López L, Rodriguez M, Garcia O, de la Peña J, Pellisé M, Rivero L, Saperas E, Pérez F, Lopez B, González JM, Álvarez A, Cobian C, Pardeiro R, Valdivielso E, Colan J, Gordillo J, Kaneko K, Albéniz E. Location, morphology and invasiveness of lateral spreading tumors in the colorectum differ between two large cohorts from an eastern and western country. Gastroenterologia y Hepatologia. 2022; 45(6). DOI:10.1016/j.gastrohep.2021.07.005. PMID:34400187. IF:1,9 (Q4/9D). Document type: Article.
Gutierrez A, Zapater P, Ricart E, Gonzalez M, Gordillo J, Olivares D, Vera I, Manosa M, Gisbert JP, Aguas M, Sanchez E, Bosca M, Laredo V, Camps B, Marin I, Zabana Y, Martin MD, Munoz R, Navarro M, Sierra E, Madero L, Vela M, Perez JL, Sainz E, Calvet X, Arias L, Morales V, Bermejo F, Fernandez L, Van M, De Castro L, Rodriguez C, Munoz C, Lorente R, Rivero M, et al. Immigrant IBD Patients in Spain Are Younger, Have More Extraintestinal Manifestations and Use More Biologics Than Native Patients. Frontiers in Medicine. 2022; 9:823900. DOI:10.3389/fmed.2022.823900. PMID:35178413. IF:3,9 (Q2/4D). Document type: Article.
Hernández A, Arranz L, Vera I, Carpio D, Calafat M, Lucendo AJ, Taxonera C, Marín S, Garcia MJ, Marín GS, Rodríguez ES, Carbajo AY, De Castro ML, Iborra M, Martin A, Rodríguez I, Busquets D, Bertoletti F, Ausín MS, Tardillo C, Malaves JH, Bujanda L, Castaño A, Domènech E, Ramos L, Merino O. Real-world use of mycophenolate mofetil in inflammatory bowel disease: Results from the ENEIDA registry. DIGESTIVE AND LIVER DISEASE. 2022; 54(5). DOI:10.1016/j.dld.2021.10.002. PMID:34862115. IF:4,5 (Q2/4D). Document type: Article.
Iborra M, Moret I, Busó E, García JL, Ricart E, Gisbert JP, Cabré E, Esteve M, Márquez L, García E, Guardiola J, Pallardó FV, Serena C, Algaba F, Domenech E, Nos P, Beltrán B. The Genetic Diversity and Dysfunctionality of Catalase Associated with a Worse Outcome in Crohn’s Disease. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022; 23(24):15881. DOI:10.3390/ijms232415881. PMID:36555526. IF:5,6 (Q1/3D). Document type: Article.
Jimenez C, Ventura M, Sala M, Calafat M, Garcia M, Cirera I, Canete N, Soriano G, Poca M, Simon M, Altamirano J, Lucey M, Garcia G, Brown RS, Schwabe RF, Verna EC, Schnabl B, Bosques F, Mathurin P, Caballeria J, Louvet A, Shawcross DL, Abraldes JG, Genesca J, Bataller R, Vargas V. Effect of rifaximin on infections, acute-on-chronic liver failure and mortality in alcoholic hepatitis: A pilot study (RIFA-AH). LIVER INTERNATIONAL. 2022; 42(5). DOI:10.1111/liv.15207. PMID:35220659. IF:6,7 (Q1/3D). Document type: Article.
Méndez N, Bugianesi E, Gish RG, Lammert F, Tilg H, Nguyen MH, Sarin SK, Fabrellas N, Zelber S, Fan J-G, Shiha G, Targher G, Zheng M-H, Chan W-K, Vinker S, Kawaguchi T, Castera L, Yilmaz Y, Korenjak M, Spearman CW, Ungan M, Palmer M, El M, Gruss H-J, Dufour J-F, Dhawan A, Wedemeyer H, George J, Valenti L, Fouad Y, Romero M, Eslam M, Abate ML, et al. [Román E, Soriano G]. Global multi-stakeholder endorsement of the MAFLD definition. Lancet Gastroenterology & Hepatology. 2022; 7(5). DOI:10.1016/S2468-1253(22)00062-0. PMID:35248211. IF:35,7 (Q1/1D). Document type: Letter.
Molero X, Ayuso JR, Balsells J, Boadas J, Busquets J, Casteras A, Concepcion M, Cuatrecasas M, Esparrach GF, Fort E, Borobia FG, Gines A, Ilzarbe L, Loras C, Masachs M, Merino X, Olsina JJ, Puig V, Salord S, Serrano T, Vaquero EC. Chronic pancreatitis for the clinician. Part 1: Etiology and diagnosis. Interdisciplinary position paper of the Societat Catalana de Digestologia and the Societat Catalana de Pancrees. Gastroenterologia y Hepatologia. 2022; 45(3). DOI:10.1016/j.gastrohep.2021.05.017. PMID:34157366. IF:1,9 (Q4/9D). Document type: Article/Practice guideline.
Molero X, Ayuso JR, Balsells J, Boadas J, Busquets J, Casteràs A, Concepción M, Cuatrecasas M, Fernàndez G, Fort E, Garcia F, Ginès À, Ilzarbe L, Loras C, Masachs M, Merino X, Olsina JJ, Puig V, Salord S, Serrano T, Vaquero EC. Chronic pancreatitis for the clinician. Part 2: Treatment and follow-up. Interdisciplinary Position Paper of the Societat Catalana de Digestologia and the Societat Catalana de Pancrees. Gastroenterologia y Hepatologia. 2022; 45(4)DOI:10.1016/j.gastrohep.2021.05.016. PMID:34171422. IF:1,9 (Q4/9D). Document type: Article.
Montoro M, Cucala M, Lanas A, Villanueva C, Hervas AJ, Alcedo J, Gisbert JP, Aisa AP, Bujanda L, Calvet X, Mearin F, Murcia O, Canelles P, Lopez SG, de Argila CM, Planella M, Quintana M, Jerico C, Erce J, Spanish Assoc Gastroenterology A. Indications and hemoglobin thresholds for red blood cell transfusion and iron replacement in adults with gastrointestinal bleeding: An algorithm proposed by gastroenterologists and patient blood management experts. Frontiers in Medicine. 2022; 9:903739. DOI:10.3389/fmed.2022.903739. PMID:36186804. IF:3,9 (Q2/4D). Document type: Review.
Riba F, Guarner C, Solanes M, Francia E, Garcia P, Machlab S, Mascort J, Mendive JM, Ortiz J, Calvet X. Indications and risk assessment of endoscopic examinations in elderly or frail people. Position paper of the Societat Catalana de Digestologia, the Societat Catalana de Geriatria i Gerontologia and the Societat Catalana de Medicina de Familia i Comunitaria. Gastroenterologia y Hepatologia. 2022; 45(10). DOI:10.1016/j.gastrohep.2022.03.004. PMID:35278501. IF:1,9 (Q4/9D). Document type: Article/Practice guideline.
Riestra S, Taxonera C, Zabana Y, Carpio D, Chaparro M, Barrio J, Rivero M, Lopez A, Esteve M, de Francisco R, Bastida G, Garcia S, Manosa M, Martin MD, Perez JL, Guardiola J, Munoz F, Arranz L, Cabriada JL, Garcia MF, Navarro M, Montoro MA, Ricart E, Bermejo F, Calvet X, Piqueras M, Garcia E, Marquez L, Minguez M, Van M, Bujanda L, Aldeguer X, Sicilia B, Iglesias E, Alcain G, Perez I, Rolle V, Castano A, Gisbert JP, Domenech E, G. Performance of Screening Strategies for Latent Tuberculosis Infection in Patients with Inflammatory Bowel Disease: Results from the ENEIDA Registry of GETECCU. Journal of Clinical Medicine. 2022; 11(13):3915. DOI:10.3390/jcm11133915. PMID:35807201. IF:3,9 (Q2/4D). Document type: Article.
Rivero L, Gavric A, Herrero J, Remedios D, Alvarez V, Albeniz E, Gordillo J, Puig I, Lopez J, Huerta A, Lopez M, Salces I, Penas B, Parejo S, Rodriguez E, Herraiz M, Carretero C, Gimeno AZ, Saperas E, Alvarez C, Arnau C, Ortiz O, Sanchez A, Jung G, Balaguer F, Pellise M. The «diagnose and leave in» strategy for diminutive rectosigmoid polyps in Lynch syndrome: a post hoc analysis from a randomized controlled trial. ENDOSCOPY. 2022; 54(01). DOI:10.1055/a-1328-5405. PMID:33271604. IF:9,3 (Q1/1D). Document type: Article.
Román E, De Francisco S, Ramos A, Ricart MT, Santesmases R, Hernández E, Campillo B, Torres A, Baciero C, Guillaumet M, Serret M, Abades M and San José A. SARS-CoV2 Infection among Nursing Students. Prospective Study. International Journal of Nursing and Health Care Research. 5: 311. DOI:10.29011/2688-9501.101311. Document type: Article.
Romero C, Gonzalez C, Hernandez P, Garcia E. Usefulness of capsule endoscopy in idiopathic complex perianal disease. Gastroenterologia y Hepatologia. 2022; 45(10). DOI:10.1016/j.gastrohep.2022.03.010. PMID:35489586. IF:1,9 (Q4/9D). Document type: Letter.
Sánchez R, Subtil JC, Martínez B, Gornals J, Guarner C, Repiso A, Peralta S, Aparicio JR, Rodríguez de Santiago E, Bazaga S, Juzgado D, González F, Albillos A, Vázquez E. EUS-guided gastroenterostomy versus duodenal self-expandable metal stent for malignant gastric outlet obstruction: results from a nationwide multicenter retrospective study (with video). GASTROINTESTINAL ENDOSCOPY. 2022; 96(6). DOI:10.1016/j.gie.2022.07.018. PMID:35870508. IF:7,7 (Q1/2D). Document type: Article.
Semmler G, Lens S, Meyer EL, Baiges A, Alvardo E, Llop E, Tellez L, Schwabl P, Mauro E, Escudé L, Díez C, Ibañez L, Puente Á, Fortea JI, Abadía M, Zanetto A, Conthe A, Hernandez H, Luzko IS, Jia J, Yoshiji H, Francque SM, Tsochatzis EA, Russo FP, Crespo G, Forns X, Bañares R, Villanueva C, Hernández V, Reiberger T, Bosch J, García JC, Mandorfer M, A study BY. Non-invasive tests for clinically significant portal hypertension after HCV cure. JOURNAL OF HEPATOLOGY. 2022; 77(6)DOI:10.1016/j.jhep.2022.08.025. PMID:36063968. IF:25,7 (Q1/1D). Document type: Article.
Soriano G, Sánchez E, Poca M, Román E, Guarner Aguilar C. Empleo de probióticos en hepatología. En: Microbiota, probióticos y prebióticos. Evidencia científica. Eds: Guillermo Álvarez Calatayud, Francisco Guarner Aguilar. Sociedad Española de Microbiota, Probióticos y Prebióticos. ERGON, Barcelona 2022, págs. 659-667. ISBN 9788418576492 SKU: 978-84-18576-49-2. Document type: Book chapter.
Ventura M, Argemi J, Jones PD, Lackner C, El Hag M, Abraldes JG, Alvarado E, Clemente A, Ravi S, Alves A, Alboraie M, Altamirano J, Barace S, Bosques F, Brown R, Caballeria J, Cabezas J, Carvalhana S, Cortez H, Costa A, Degre D, Fernandez C, Ganne N, Garcia G, Genesca J, Koskinas J, Lanthier N, Louvet A, Lozano JJ, Lucey MR, Masson S, Mathurin P, Mendez N, et al. [Szafranska J, Villanueva C]. Clinical, histological and molecular profiling of different stages of alcohol-related liver disease. GUT. 2022; 71(9):324295. DOI:10.1136/gutjnl-2021-324295. PMID:34992134. IF:24,5 (Q1/1D). Document type: Article.
Villanueva C, Torres F, Sarin SK, Shah HA, Tripathi D, Brujats A, Rodrigues SG, Bhardwaj A, Azam Z, Hayes PC, Jindal A, Abid S, Alvarado E, Bosch J, Carvedilol IPD MA GRP, Baveno Cooperation EASL C. Carvedilol reduces the risk of decompensation and mortality in patients with compensated cirrhosis in a competing-risk meta-analysis. JOURNAL OF HEPATOLOGY. 2022; 77(4). DOI:10.1016/j.jhep.2022.05.021. PMID:35661713. IF:25,7 (Q1/1D). Document type: Article.
Zabana Y, Marin I, Rodriguez I, Vera I, Martin MD, Guerra I, Gisbert JP, Mesonero F, Benitez O, Taxonera C, Ponferrada A, Piqueras M, Lucendo AJ, Caballol B, Manosa M, Martinez P, Bosca M, Gordillo J, Bujanda L, Mancenido N, Martinez T, Lopez A, Rodriguez C, Garcia S, Vega P, Rivero M, Melcarne L, Calvo M, Iborra M, de MB, Sicilia B, Barrio J, Perez JL, et al. [Bertoletti F]. Nationwide COVID-19-EII Study: Incidence, Environmental Risk Factors and Long-Term Follow-Up of Patients with Inflammatory Bowel Disease and COVID-19 of the ENEIDA Registry. Journal of Clinical Medicine. 2022; 11(2):421. DOI:10.3390/jcm11020421. PMID:35054116. IF:3,9 (Q2/4D). Document type: Article.
Zabana Y, Marin I, Rodriguez I, Vera I, Martin MD, Guerra I, Gisbert JP, Mesonero F, Benitez O, Taxonera C, Ponferrada A, Piqueras M, Lucendo AJ, Caballol B, Manosa M, Martinez P, Bosca M, Gordillo J, Bujanda L, Mancenido N, Martinez T, Lopez A, Rodriguez C, Garcia S, Vega P, Rivero M, Melcarne L, Calvo M, Iborra M, de Acosta MB, Sicilia B, Barrio J, Calle JLP, et al. [Bertoletti F]. Risk Factors for COVID-19 in Inflammatory Bowel Disease: A National, ENEIDA-Based Case-Control Study (COVID-19-EII). Journal of Clinical Medicine. 2022; 11(24):7540. DOI:10.3390/jcm11247540. PMID:36556155. IF:3,9 (Q2/4D). Document type: Article.

Publicaciones 2021

Albeniz E, Enguita M, Gimeno AZ, de Tejada AH, Nogales O, Espinos JC, Sanchez JR, Roson P, Guarner C, Marin JC, Bhandari P, Spadaccini M, Repici A, Hassan C, Alvarez MA, Beroiz BI. The Answer to «When to Clip» After Colorectal Endoscopic Mucosal Resection Based on a Cost-Effectiveness Analysis. AMERICAN JOURNAL OF GASTROENTEROLOGY. 2021; 116(2). DOI:10.14309/ajg.0000000000000943. PMID:33149001. IF:12,045.
Algaba A, Guerra I, Ricart E, Iglesias E, Mañosa M, Gisbert JP, Guardiola J, Mínguez M, Castro B, de Francisco R, Nos P, Bertoletti F, Mesonero F, Barrio J, Martín-Arranz MD, Calvet X, García-López S, Sicilia B, Alcaín G, Esteve M, Márquez L, Piqueras M, Jiménez L, Perez-Calle JL, Bujanda L, García-Sepulcre M, Fernández A, Moraleja I, Lorente RH, Et al.; Spanish GETECCU Group (ENEIDA Project). Extraintestinal Manifestations in Patients with Inflammatory Bowel Disease: Study Based on the ENEIDA Registry. DIGESTIVE DISEASES AND SCIENCES. 2021;66(6):2014-2023. DOI:10.1007/s10620-020-06424-x. PMID: 32671587. IF:3,487.
Ampuero J, Aller R, Gallego R, Crespo J, Abad J, Gonzalez A, Gomez J, Caballeria J, Lo Iacono O, Ibanez L, Garcia J, Martin R, Frances R, Fernandez C, Diago M, Soriano G, Andrade RJ, Latorre R, Jorquera F, Morillas RM, Escudero D, Estevez P, Hernandez M, Augustin S, Pareja MJ, Banales JM, Aspichueta P, Benlloch S, Rosales JM, Salmeron J, Turnes J, Romero M. Definite and indeterminate nonalcoholic steatohepatitis share similar clinical features and prognosis: A longitudinal study of 1893 biopsy-proven nonalcoholic fatty liver disease subjects. LIVER INTERNATIONAL. 2021; 41(9). DOI:10.1111/liv.14898. PMID:33896100. IF:8,754.
Arab JP, Diaz LA, Baeza N, Idalsoaga F, Fuentes E, Arnold J, Ramirez CA, Morales D, Ventura M, Alvarado E, Zhang W, Clark V, Simonetto D, Ahn JC, Buryska S, Mehta TI, Stefanescu H, Horhat A, Bumbu A, Dunn W, Attar B, Agrawal R, Haque ZS, Majeed M, Cabezas J, Garcia I, Parker R, Cuyas B, Poca M, Soriano G, Sarin SK, Maiwall R, Jalal PK, Abdulsada S, et al. Identification of optimal therapeutic window for steroid use in severe alcohol-associated hepatitis: A worldwide study. JOURNAL OF HEPATOLOGY. 2021; 75(5). DOI:10.1016/j.jhep.2021.06.019. PMID:34166722. IF:30,083.
Arroyo JA, Julve J, Vlacho B, Corcoy R, Ponte P, Roman E, Navas E, Llaurado G, Franch J, Domingo P, Mauricio D. Previous Vitamin D Supplementation and Morbidity and Mortality Outcomes in People Hospitalised for COVID19: A Cross-Sectional Study. Frontiers in Public Health. 2021; 9:758347. DOI:10.3389/fpubh.2021.758347. PMID:34631653. IF:6,461.
Calafat M, Gonzalez C, Fortuny M, Roig C, Calm A, Mombiela A, Canete F, Bertoletti F, Gonzalez L, Teller M, Gordillo J, Manosa M, Garcia E, Domenech E. Impact of immunosuppressants on SARS-CoV-2 infection in elderly patients with inflammatory bowel disease. AGING CLINICAL AND EXPERIMENTAL RESEARCH. 2021; 33(8). DOI:10.1007/s40520-021-01917-9. PMID:34164799. IF:4,481.
Casanova MJ, Chaparro M, Nantes O, Benitez JM, Rojas M, Castro J, Huguet JM, Martin A, Aicart M, Tosca J, Martin MD, Gonzalez C, Manosa M, Leo E, Lamuela LJ, Perez I, Bujanda L, Hinojosa J, Pajares R, Arguelles F, Perez JL, Rodriguez GE, Guardiola J, Barreiro M, Gisbert JP. Clinical outcome after anti-tumour necrosis factor therapy discontinuation in 1000 patients with inflammatory bowel disease: the EVODIS long-term study. ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2021; 53(12). DOI:10.1111/apt.16361. PMID:33962482. IF:9,524.
Chaparro M, Garre A, Iborra M, Sierra M, Barreiro M, Fernandez A, de Castro L, Bosca M, Casanova MJ, Lopez A, Lorente R, Rodriguez C, Carbajo AY, Arroyo MT, Gutierrez A, Hinojosa J, Martinez T, Villoria A, Bermejo F, Busquets D, Camps B, Canete F, Mancenido N, Monfort D, Navarro M, Perez JL, Ramos L, Rivero M, Angueira T, et al. [Gonzalez C, Garcia E]. Effectiveness and Safety of Ustekinumab in Ulcerative Colitis: Real-world Evidence from the ENEIDA Registry. Journal of Crohns & Colitis. 2021; 15(11). DOI:10.1093/ecco-jcc/jjab070. PMID:33860795. IF:10,020.
Chaparro M, Garre A, Mesonero F, Rodriguez C, Barreiro M, Martinez J, Arroyo MT, Mancenido N, Sierra M, Vera I, Casanova MJ, Nos P, Gonzalez C, Martinez T, Bosca M, Calafat M, Busquets D, Girona E, Llao J, Martin MD, Piqueras M, Ramos L, Suris G, Bermejo F, Carbajo AY, Casas D, Fernandez A, Garcia MJ, Ginard D, Gutierrez A, Hernandez L, et al. Tofacitinib in Ulcerative Colitis: Real-world Evidence From the ENEIDA Registry. Journal of Crohns & Colitis. 2021; 15(1). DOI:10.1093/ecco-jcc/jjaa145. PMID:32969471. IF:10,020.
Chaparro M, Garre A, Ortiz AN, Palomares MTDL, Rodriguez C, Riestra S, Vela M, Benitez JM, Salgado EF, Rodriguez ES, Hernandez V, Ferreiro R, Diaz AP, Barrio J, Huguet JM, Sicilia B, Martin MD, Calvet X, Ginard D, Alonso I, Fernandez L, Trastoy PV, Rivero M, Vera I, Vega P, Navarro P, Sierra M, Cabriada JL, Aguas M, Vicente R, Navarro M, Echarri A, et al. [Gordillo J]. Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study. Journal of Clinical Medicine. 2021; 10(13):2885. DOI:10.3390/jcm10132885. PMID:34209680. IF:4,964.
de Paredes A, Villanueva C, Blanco C, Genesca J, Manicardi N, Garcia JC, Calleja JL, Aracil C, Morillas RM, Poca M, Penas B, Augustin S, Abraldes JG, Alvarado E, Royo F, Garcia ML, Falcon JM, Banares R, Bosch J, Gracia J, Albillos A. Serum miR-181b-5p predicts ascites onset in patients with compensated cirrhosis. Jhep Reports. 2021; 3(6):100368. DOI:10.1016/j.jhepr.2021.100368. PMID:34712934. IF:9,917.
Fernandez C, Alvarez M, Quintana I, Lopez A, Amigo J, Cameselle JM, Roman E, Gonzalez D, Llor X, Bujanda L, Bessa X, Jover R, Balaguer F, Castells A, Castellvi S, Capella G, Carracedo A, Valle L, Ruiz C. Exome sequencing of early-onset patients supports genetic heterogeneity in colorectal cancer. Scientific Reports. 2021; 11(1):11135. DOI:10.1038/s41598-021-90590-z. PMID:34045552. IF:4,996.
Garcia A, Loras C, Guarner C, Velasquez JG, Andujar X, Salord S, Busquets J, Tebe C, Laquente B, Gornals JB. Is a coaxial plastic stent within a lumen-apposing metal stent useful for the management of distal malignant biliary obstruction?. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES. 2021; 35(8). DOI:10.1007/s00464-021-08435-9. PMID:33721090. IF:3,453.
Gil A, Ampuero J, Rojas A, Gallego R, Munoz R, Rico MC, Millan R, Garcia R, Frances R, Soriano G, Romero M. Development and Validation of a Clinical-Genetic Risk Score to Predict Hepatic Encephalopathy in Patients With Liver Cirrhosis. AMERICAN JOURNAL OF GASTROENTEROLOGY. 2021; 116(6). DOI:10.14309/ajg.0000000000001164. PMID:33852451. IF:12,045.
Hernandez E, Santesmases R, Roman E, Porcel MA, Busquet AT, Perez MB, Verdu J. Prevalence and characteristics of older people with pressure ulcers and legs ulcers, in nursing homes in Barcelona. Journal of Tissue Viability. 2021; 30(1). DOI:10.1016/j.jtv.2021.01.003. PMID:33485786. IF:3,374.
Julia A, Martinez SH, Domenech E, Canete JD, Ferrandiz C, Tornero J, Gisbert JP, Fernandez A, Dauden E, Barreiro M, Perez C, Queiro R, Lopez FJ, Carazo JLS, Mendoza JL, Alperi M, Montilla C, Venegas JJP, Munoz F, Castaneda S, Lasanta ML, Marsal S, Fonseca E, Rodriguez J, Carreira P, Garcia V, Pinto JA, Puig L, Ricart E, Blanco F, Gratacos J, et al. [Garcia E, Diaz C]. Food groups associated with immune-mediated inflammatory diseases: a Mendelian randomization and disease severity study. EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2021; 75(9). DOI:10.1038/s41430-021-00913-6. PMID:33893449. IF:4,884.
Llao J, Masnou H, Romero C, Bargallo A, Gely C, Manosa M, Gordillo J, Garcia E, Domenech E. Noninvasive assessment of liver fibrosis in Crohn’s disease patients exposed to methotrexate. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY. 2021; 33(6). DOI:10.1097/MEG.0000000000001799. PMID:32804842. IF:2,586.
Martinez J, Hernandez V, Rodriguez E, Tellez L, Procopet B, Giraldez A, Amitrano L, Villanueva C, Thabut D, Ibanez L, Silva G, Genesca J, Bureau C, Trebicka J, Banares R, Krag A, Llop E, Laleman W, Palazon JM, Castellote J, Rodrigues S, Gluud LL, Noronha C, Canete N, Rodriguez M, Ferlitsch A, Schwarzer R, Mundi JL, Gronbaek H, Hernandez M, et al. [Alvarado E]. Bacterial infections in patients with acute variceal bleeding in the era of antibiotic prophylaxis. JOURNAL OF HEPATOLOGY. 2021; 75(2). DOI:10.1016/j.jhep.2021.03.026. PMID:33845059. IF:30,083.
Massey V, Parrish A, Argemi J, Moreno M, Mello A, Garcia M, Altamirano J, Odena G, Dubuquoy L, Louvet A, Martinez C, Adrover A, Affo S, Morales O, Sancho P, Millan C, Alvarado E, Morales D, Caballeria J, Mann J, Cao S, Sun ZL, Shah V, Cameron A, Mathurin P, Snider N, Villanueva C, Morgan TR, Guinovart J, Vadigepalli R, Bataller R. Integrated Multiomics Reveals Glucose Use Reprogramming and Identifies a Novel Hexokinase in Alcoholic Hepatitis. GASTROENTEROLOGY. 2021; 160(5). DOI:10.1053/j.gastro.2020.12.008. PMID:33309778. IF:33,883.
Mesonero F, Castro J, Benitez JM, Camps B, Iborra M, Lopez A, Torres P, Esteve M, Tosca J, Bertoletti F, Almela P, Calvet X, Vera I, Bujanda L, Gomollon F, Rodriguez C, Antolin B, Busquets D, Hernandez A, Rivero M, Miquel D, Castano A, Gisbert JP, Domenech E, Lopez A. Effectiveness and safety of methotrexate monotherapy in patients with Crohn’s disease refractory to anti-TNF-alpha: results from the ENEIDA registry. ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2021; 53(9). DOI:10.1111/apt.16315. PMID:33715177. IF:9,524.
Nicoara O, Han GH, Rudler M, Angrisani D, Monescillo A, Torres F, Casanovas G, Bosch J, Lv Y, Thabut D, Fan DM, Hernandez V, Garcia JC, Alvarado E, Ripoll C. Effects of Early Placement of Transjugular Portosystemic Shunts in Patients With High-Risk Acute Variceal Bleeding: a Meta-analysis of Individual Patient Data. GASTROENTEROLOGY. 2021; 160(1). DOI:10.1053/j.gastro.2020.09.026. PMID:32980344. IF:33,883.
Perea L, Rodriguez L, Nieto JC, Zamora C, Canto E, Soriano G, Poca M, Blanco P, Navarro F, Muniesa M, Vidal S. Bacteriophages immunomodulate the response of monocytes. EXPERIMENTAL BIOLOGY AND MEDICINE. 2021; 246(11). DOI:10.1177/1535370221995154. PMID:33641443. IF:4,088.
Reig A, Alvarez C, Vergara M, Gomez E, Gallego A, Perez IM, Fabrega E, Hernandez M, Berenguer M, Estevez P, Arencibia A, Morillas RM, Horta D, Albillos A, Casado M, De la Cruz G, Fernandez E, Molina E, Hijona L, Diago M, Fernandez CM, Gonzalez JM, Sala M, Gomez J, Romero M, Suarez F, Vargas V, Ferre C, Andrade RJ, Chahri N, Pares A. Obeticholic Acid and Fibrates in Primary Biliary Cholangitis: Comparative Effects in a Multicentric Observational Study. AMERICAN JOURNAL OF GASTROENTEROLOGY. 2021; 116(11). DOI:10.14309/ajg.0000000000001343. PMID:34158466. IF:12,045.
Rodríguez de Santiago E, Shimamura Y, Pioche M, Eleftheriadis N, Albéniz E, Bechara R, Yan Chiu PW, Guarner-Argente C, Herreros de Tejada A, Uchima H, Fujiyoshi Y, Ponchon T, González-Gete G, Hew S, Murzi-Pulgar M, Matallana V, Parejo-Carbonell S, Estremera-Arévalo F, Moll F, Onimaru M, Inoue H. Safety and effectiveness of peroral endoscopic myotomy in patients on antiplatelet or anticoagulant therapy: an international multicenter case-control study. GASTROINTESTINAL ENDOSCOPY. 2021;93(4):839-849. DOI:10.1016/j.gie.2020.07.030. PMID: 32717366. IF:10,396.
Román E, Parramón M, Flavià M, Gely C, Poca M, Gallego A, Santesmases R, Hernández E, Nieto JC, Urgell E, Alvarado-Tapias E, Vidal S, Ferrero-Gregori A, Vargas V, Guarner C, Soriano G. Frailty in outpatients with cirrhosis: A prospective observational study. Liver International. 2021;41(2):357-368. DOI:10.1111/liv.14694. PMID: 33030788. IF:8,754.
Roman E, Poca M, Amoros G, Rosell J, Gely C, Nieto JC, Vidal S, Urgell E, Ferrero A, Alvarado E, Cuyas B, Hernandez E, Santesmases R, Guarner C, Escorsell A, Soriano G. Phase angle by electrical bioimpedance is a predictive factor of hospitalisation, falls and mortality in patients with cirrhosis. Scientific Reports. 2021; 11(1):20415. DOI:10.1038/s41598-021-99199-8. PMID:34650096. IF:4,996.
Stephens C, Robles M, Medina I, Garcia M, Ortega A, Sanabria J, Gonzalez A, Alvarez I, Slim M, Jimenez M, Gonzalez R, Fernandez MC, Casado M, Soriano G, Roman E, Hallal H, Romero M, Castiella A, Conde I, Prieto M, Moreno JM, Giraldez A, Moreno JM, Kaplowitz N, Lucena MI, Andrade RJ, Participating CTR. Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry. JOURNAL OF HEPATOLOGY. 2021; 75(1). DOI:10.1016/j.jhep.2021.01.029. PMID:33539847. IF:30,083.
Trebicka J, Fernandez J, Papp M, Caraceni P, Laleman W, Gambino C, Giovo I, Uschner FE, Jansen C, Jimenez C, Mookerjee R, Gustot T, Albillos A, Banares R, Jarcuska P, Steib C, Reiberger T, Acevedo J, Gatti P, Shawcross DL, Zeuzem S, Zipprich A, Piano S, Berg T, Bruns T, Danielsen KV, Coenraad M, Merli M, Stauber R, Zoller H, et al. [Soriano G, Alvarado E]. PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis. JOURNAL OF HEPATOLOGY. 2021; 74(5). DOI:10.1016/j.jhep.2020.11.019. PMID:33227350. IF:30,083.
Ventura M, Simon M, Poca M, Ariza X, Masnou H, Sanchez J, Llop E, Canete N, Martin M, Amador A, Martinez J, Clemente A, Puente A, Torrens M, Alvarado E, Napoleone L, Miquel M, Ardevol A, Rodrigo MC, Calleja JL, Sole C, Soriano G, Genesca J. Effects of Albumin on Survival after a Hepatic Encephalopathy Episode: Randomized Double-Blind Trial and Meta-Analysis. Journal of Clinical Medicine. 2021; 10(21):4885. DOI:10.3390/jcm10214885. PMID:34768404. IF:4,964.
Villanueva C, Albillos A, Genesca J, Garcia JC, Brujats A, Calleja JL, Aracil C, Banares R, Morillas RM, Poca M, Penas B, Augustin S, Abraldes JG, Alvarado E, Torres F, Bosch J. Bacterial infections adversely influence the risk of decompensation and survival in compensated cirrhosis. JOURNAL OF HEPATOLOGY. 2021; 75(3). DOI:10.1016/j.jhep.2021.04.022. PMID:33905794. IF:30,083.
Weersink RA, Alvarez-Alvarez I, Medina-Cáliz I, Sanabria-Cabrera J, Robles-Díaz M, Ortega-Alonso A, García-Cortés M, Bonilla E, Niu H, Soriano G, Jimenez-Perez M, Hallal H, Blanco S, Kaplowitz N, Lucena MI, Andrade RJ, [Antonijoan R, Gonzalez-Gallego J]. Clinical Characteristics and Outcome of Drug-Induced Liver Injury in the Older Patients: From the Young-Old to the Oldest-Old. CLINICAL PHARMACOLOGY & THERAPEUTICS. 2021;109(4):1147-1158. DOI:10.1002/cpt.2108. PMID: 33179256. IF:6,903.

Presentación

Principales líneas de investigación

Investigación experimental

Modelo experimental de rata con cirrosis y ascitis.
Mecanismos de translocación bacteriana en rata con cirrosis y su prevención.
Modelo experimental de peritonitis bacteriana espontánea e inducida: fisiopatología y tratamiento.
Perfil de expresión miRNAs en la enfermedad inflamatoria intestinal después de la estimulación con receptores de ligandos tipo toll.

Investigación clínica

Fisiopatología, diagnóstico, tratamiento y prevención de las infecciones bacterianas, ascitis y síndrome hepatorrenal en la cirrosis.
Diagnóstico y tratamiento de la encefalopatía hepática en la cirrosis.
Discapacidad cognitiva, caídas y calidad de vida en pacientes con cirrosis.
Fisiopatología, diagnóstico, tratamiento y prevención de la hemorragia digestiva por hipertensión portal de origen no varicoso.
La hepatitis crónica B y C: diagnóstico y tratamiento.
Diagnóstico y tratamiento del hepatocarcinoma.
Fisiopatología, diagnóstico y tratamiento de la enfermedad inflamatoria intestinal.
Diagnóstico y tratamiento en endoscopia gastrointestinal avanzada.
Diagnóstico y tratamiento de la pancreatitis aguda.
Prevención de la pancreatitis aguda post-CPRE.
La pancreatitis crónica y las neoplasias de páncreas: estudios moleculares, la detección precoz y el tratamiento.

Retos

Consolidación del grupo de investigación CIBEREHD mediante el estudio de las complicaciones en cirrosis.
Expandir el laboratorio de investigación en hepatología y desarrollar nuevos estudios.
Consolidar el grupo de investigación del portal de hipertensión.
Consolidar la línea de investigación de enfermedad pancreática.
Consolidar la línea de investigación en enfermedad inflamatoria intestinal.
Consolidar la línea de investigación en pólipos y cáncer de colon.
Desarrollar una línea de investigación en endoscopia digestiva.

Equipo

Coordinación del grupo

ESCORSELL MAÑOSA, Mª ANGELS FGS
MEscorsell@santpau.cat

Miembros

Producción científica

Publicaciones 2022

(JIF 2022)

Baiges A, Cerda E, Amicone C, Téllez L, Alvarado E, Puente A, Fortea JI, Llop E, Rocha F, Orts L, Ros O, Vizcarra P, Zekrini K, Lounes OA, Touati G, Jiménez N, Serrano MJ, Falgà A, Magaz M, Olivas P, Betancourt F, Perez V, Turon F, Payancé A, Goria O, Rautou P-E, Hernández V, Villanueva C, Albillos A, Plessier A, García J-C. Impact of SARS-CoV-2 Pandemic on Vascular Liver Diseases. Clinical Gastroenterology and Hepatology. 2022; 20(7). DOI:10.1016/j.cgh.2021.12.032. PMID:34968728. IF:12,6 (Q1/1D). Document type: Article.
Barreiro M, Riestra S, Calafat M, Soto MP, Calvo M, Rodriguez ES, Caballol B, Vela M, Rivero M, Munoz F, de Castro L, Calvet X, Garcia FJ, Fornals AU, Ferreiro R, Gonzalez-Muñoza C, Chaparro M, Bujanda L, Sicilia B, Alfambra E, Rodriguez A, Fernandez RP, Rodriguez C, Almela P, Arguelles F, Busquets D, Tamarit S, Castro CR, Jimenez L, Marin I, Alcaide N, Fernandez E, et al. Management and Long-term Outcomes of Crohn’s Disease Complicated with Enterocutaneous Fistula: ECUFIT Study from GETECCU. Journal of Crohns & Colitis. 2022; 16(7). DOI:10.1093/ecco-jcc/jjac016. PMID:35104314. IF:8 (Q1/2D). Document type: Article.
Bassegoda O, Olivas P, Turco L, Mandorfer M, Serra M, Tellez L, Kwanten W, Laroyenne A, Farcau O, Alvarado E, Moga L, Vuille E, Fortea JI, Ibañez L, Tosetti G, Vanwolleghem T, Larrue H, Burgos D, Stefanescu H, Paternostro R, Cippitelli A, Lens S, Augustin S, Llop E, Laleman W, Trebicka J, Chang J, Masnou H, Zipprich A, Miceli F, Semmler G, Forns X, Primignani M, et al. [Villanueva C]. Decompensation in Advanced Nonalcoholic Fatty Liver Disease May Occur at Lower Hepatic Venous Pressure Gradient Levels Than in Patients With Viral Disease. Clinical Gastroenterology and Hepatology. 2022; 20(10). DOI:10.1016/j.cgh.2021.10.023. PMID:34688952. IF:12,6 (Q1/1D). Document type: Article.
Batista G, Marin I, Fores A, Garcia E, Arguelles F, Tagarro I, Fernandez A, Montoto C, Aparicio J, Aguas M, Santos J, Bosca MM, Ferreiro R, Merino O, Aldeguer X, Corttes X, Sicilia B, Mesonero F, Barreiro M. Treatment patterns and intensification within 5 year of follow-up of the first-line anti-TNF alpha used for the treatment of IBD: Results from the VERNE study. DIGESTIVE AND LIVER DISEASE. 2022; 54(1). DOI:10.1016/j.dld.2021.06.005. PMID:34244110. IF:4,5 (Q2/4D). Document type: Article.
Calafat M, Mañosa M, Ricart E, Nos P, Iglesias E, Vera I, López A, Guardiola J, Taxonera C, Mínguez M, Martín MD, de Castro L, de Francisco R, Rivero M, Garcia E, Calvet X, García S, Márquez L, Gomollón F, Barrio J, Esteve M, Muñoz F, Gisbert JP, Gutiérrez A, Hinojosa J, Argüelles F, Busquets D, Bujanda L, Pérez JL, Sicilia B, Merino O, Martínez P, Bermejo F, Lorente R, Barreiro M, Rodríguez C, García MF, Monfort D, Cañete F, Domènech E. Risk of Immunomediated Adverse Events and Loss of Response to Infliximab in Elderly Patients with Inflammatory Bowel Disease: A Cohort Study of the ENEIDA Registry. Journal of Crohns & Colitis. 2022; 16(6). DOI:10.1093/ecco-jcc/jjab213. PMID:34864947. IF:8 (Q1/2D). Document type: Article.
Casado S, Velasco M, Catala C, Leyton A, Gutierrez R, Suarez B, Armiger N, Carreras E, Esteller M, Ricart E, Ordas I, Gisbert JP, Chaparro M, Esteve M, Marquez L, Busquets D, Iglesias E, Garcia E, Martin MD, Lohmann J, Ayata CK, Niess JH, Engel P, Panes J, Salas A, Domenech E, Lozano F, G. Experimental and genetic evidence for the impact of CD5 and CD6 expression and variation in inflammatory bowel disease. Frontiers in Immunology. 2022; 13:966184. DOI:10.3389/fimmu.2022.966184. PMID:36211446. IF:7,3 (Q1/3D). Document type: Article.
Chaparro M, Baston I, Fernandez E, Garcia JG, Ramos L, Palomares MTDL, Arguelles F, Flores EI, Cabello M, Iturria SR, Ortiz AN, Charro M, Ginard D, Sadornil CD, Ochoa OM, Busquets D, Iyo E, Casbas AG, de la Piscina PR, Bosca MM, Arroyo M, Garcia MJ, Hinojosa E, Gordillo J, Montiel PM, Jimenez BV, Ivorra CQ, Moron JMV, Huguet JM, Gonzalez Y, Santos A, Amo VM, et al. Long-Term Real-World Effectiveness and Safety of Ustekinumab in Crohn’s Disease Patients: The SUSTAIN Study. INFLAMMATORY BOWEL DISEASES. 2022; 28(11). DOI:10.1093/ibd/izab357. PMID:35166347. IF:4,9 (Q2/3D). Document type: Article.
Chaparro M, Baston I, Salgado EF, Garcia JG, Ramos L, Palomares MTDL, Arguelles F, Flores EI, Cabello M, Iturria SR, Ortiz AN, Charro M, Ginard D, Sadornil CD, Ochoa OM, Busquets D, Iyo E, Casbas AG, de la Piscina PR, Bosca MM, Arroyo M, Garcia MJ, Hinojosa E, Gordillo J, Montiel PM, Jimenez BV, Ivorra CQ, Moron JMV, Huguet JM, Gonzalez Y, Santos A, Amo VM, et al. Using Interpretable Machine Learning to Identify Baseline Predictive Factors of Remission and Drug Durability in Crohn’s Disease Patients on Ustekinumab. Journal of Clinical Medicine. 2022; 11(15):4518. DOI:10.3390/jcm11154518. PMID:35956133. IF:3,9 (Q2/4D). Document type: Article.
de Franchis R, Bosch J, Garcia G, Reiberger T, Ripoll C, Abraldes JG, Albillos A, Baiges A, Bajaj J, Bañares R, Barrufet M, Benajiba L, Berzigotti A, Bureau C, Calvaruso V, Cardenas A, D’Amico G, De Gottardi A, Dell’Era A, Escorsell A, Fallowfield J, Ferral H, Francque S, Gaba R, Garcia JC, Genescà J, Rodrigues SG, Gracia J, Han G, Hernandez V, Jia J, Kiladjian JJ, Krag A, et al. [Villanueva C]. Baveno VII – Renewing consensus in portal hypertension. JOURNAL OF HEPATOLOGY. 2022; 76(4). DOI:10.1016/j.jhep.2021.12.022. PMID:35120736. IF:25,7 (Q1/1D). Document type: Review.
de Santiago ER, Aldehuelo RS, Pons FR, Escaja CR, Fernandez G, Canete A, Aracil CF, Perez D, Leon RR, Marcos HM, Delgado PG, Garcia A, Guarner C, Muriel A, de la Fuente E, de Paredes A, Parejo S, Tellez L, Senosiain C, Burgos D, Aicart M, Munoz BM, Penas B, Pagano G, Urquiza GC, Ferreruela MU, de Jorge MA, Barreiro E, Fraile M, Gomez A, Altamirano MI, Esteban MN, Ruiz M, Arribas J, de Frutos D, Herreros A, Arias ML, Roldan M, Martin A, Zamora J, Vazquez E, Albillos A. Endoscopy-Related Bleeding and Thromboembolic Events in Patients on Direct Oral Anticoagulants or Vitamin K Antagonists. Clinical Gastroenterology and Hepatology. 2022; 20(3). DOI:10.1016/j.cgh.2020.11.037. PMID:33279783. IF:12,6 (Q1/1D). Document type: Article.
Gallego-Durán R, Albillos A, Ampuero J, Arechederra M, Bañares R, Blas A, Berná G, Caparrós E, Delgado TC, Falcón JM, Francés R, Fernández MG, Graupera I, Iruzubieta P, Nevzorova YA, Nogueiras R, Macías RIR, Martín F, Sabio G, Soriano G, Vaquero J, Cubero FJ, Gracia J. Metabolic-associated fatty liver disease: From simple steatosis toward liver cirrhosis and potential complications. Proceedings of the Third Translational Hepatology Meeting, organized by the Spanish Association for the Study of the Liver (AEEH). Gastroenterologia y Hepatologia. 2022; 45(9). DOI:10.1016/j.gastrohep.2022.02.005. PMID:35248669. IF:1,9 (Q4/9D). Document type: Review.
Gil A, Rojas A, Garcia MR, Munoz R, Gallego R, Maya D, Montero R, Gato S, Gallego J, Frances R, Soriano G, Ampuero J, Romero M. Impact of a Loss-of-Function Variant in HSD17B13 on Hepatic Decompensation and Mortality in Cirrhotic Patients. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022; 23(19):11840. DOI:10.3390/ijms231911840. PMID:36233142. IF:5,6 (Q1/3D). Document type: Article.
González C, Briones J, Sang H, García E. Marginal zone lymphoma under anti-TNF treatment in Crohn disease. Gastroenterologia y Hepatologia. 2022; 45(5). DOI:10.1016/j.gastrohep.2021.05.010. PMID:34118314. IF:1,9 (Q4/9D). Document type: Letter.
Gonzalez L, Bazaga S, Murzi M, Brujats A, Trias M, de Riba B, Romito R, Colan J, Concepcion M, Gordillo J, Pernas JC, Poca M, Soriano G, Guarner C. Predictors of the need for necrosectomy in patients with walled-off pancreatic necrosis treated with lumen apposition metal stents. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES. 2022; 36(2). DOI:10.1007/s00464-021-08411-3. PMID:33660124. IF:3,1 (Q1/3D). Document type: Article.
Guarner C, Ikematsu H, Osera S, Fraile M, Ibañez B, Marra C, Jerusalén C, Alonso PA, Martinez D, Soto S, Ramos F, Alvarez MA, Rodriguez J, Múgica F, Nogales O, Herreros de Tejada A, Redondo E, Martínez J, López L, Rodriguez M, Garcia O, de la Peña J, Pellisé M, Rivero L, Saperas E, Pérez F, Lopez B, González JM, Álvarez A, Cobian C, Pardeiro R, Valdivielso E, Colan J, Gordillo J, Kaneko K, Albéniz E. Location, morphology and invasiveness of lateral spreading tumors in the colorectum differ between two large cohorts from an eastern and western country. Gastroenterologia y Hepatologia. 2022; 45(6). DOI:10.1016/j.gastrohep.2021.07.005. PMID:34400187. IF:1,9 (Q4/9D). Document type: Article.
Gutierrez A, Zapater P, Ricart E, Gonzalez M, Gordillo J, Olivares D, Vera I, Manosa M, Gisbert JP, Aguas M, Sanchez E, Bosca M, Laredo V, Camps B, Marin I, Zabana Y, Martin MD, Munoz R, Navarro M, Sierra E, Madero L, Vela M, Perez JL, Sainz E, Calvet X, Arias L, Morales V, Bermejo F, Fernandez L, Van M, De Castro L, Rodriguez C, Munoz C, Lorente R, Rivero M, et al. Immigrant IBD Patients in Spain Are Younger, Have More Extraintestinal Manifestations and Use More Biologics Than Native Patients. Frontiers in Medicine. 2022; 9:823900. DOI:10.3389/fmed.2022.823900. PMID:35178413. IF:3,9 (Q2/4D). Document type: Article.
Hernández A, Arranz L, Vera I, Carpio D, Calafat M, Lucendo AJ, Taxonera C, Marín S, Garcia MJ, Marín GS, Rodríguez ES, Carbajo AY, De Castro ML, Iborra M, Martin A, Rodríguez I, Busquets D, Bertoletti F, Ausín MS, Tardillo C, Malaves JH, Bujanda L, Castaño A, Domènech E, Ramos L, Merino O. Real-world use of mycophenolate mofetil in inflammatory bowel disease: Results from the ENEIDA registry. DIGESTIVE AND LIVER DISEASE. 2022; 54(5). DOI:10.1016/j.dld.2021.10.002. PMID:34862115. IF:4,5 (Q2/4D). Document type: Article.
Iborra M, Moret I, Busó E, García JL, Ricart E, Gisbert JP, Cabré E, Esteve M, Márquez L, García E, Guardiola J, Pallardó FV, Serena C, Algaba F, Domenech E, Nos P, Beltrán B. The Genetic Diversity and Dysfunctionality of Catalase Associated with a Worse Outcome in Crohn’s Disease. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022; 23(24):15881. DOI:10.3390/ijms232415881. PMID:36555526. IF:5,6 (Q1/3D). Document type: Article.
Jimenez C, Ventura M, Sala M, Calafat M, Garcia M, Cirera I, Canete N, Soriano G, Poca M, Simon M, Altamirano J, Lucey M, Garcia G, Brown RS, Schwabe RF, Verna EC, Schnabl B, Bosques F, Mathurin P, Caballeria J, Louvet A, Shawcross DL, Abraldes JG, Genesca J, Bataller R, Vargas V. Effect of rifaximin on infections, acute-on-chronic liver failure and mortality in alcoholic hepatitis: A pilot study (RIFA-AH). LIVER INTERNATIONAL. 2022; 42(5). DOI:10.1111/liv.15207. PMID:35220659. IF:6,7 (Q1/3D). Document type: Article.
Méndez N, Bugianesi E, Gish RG, Lammert F, Tilg H, Nguyen MH, Sarin SK, Fabrellas N, Zelber S, Fan J-G, Shiha G, Targher G, Zheng M-H, Chan W-K, Vinker S, Kawaguchi T, Castera L, Yilmaz Y, Korenjak M, Spearman CW, Ungan M, Palmer M, El M, Gruss H-J, Dufour J-F, Dhawan A, Wedemeyer H, George J, Valenti L, Fouad Y, Romero M, Eslam M, Abate ML, et al. [Román E, Soriano G]. Global multi-stakeholder endorsement of the MAFLD definition. Lancet Gastroenterology & Hepatology. 2022; 7(5). DOI:10.1016/S2468-1253(22)00062-0. PMID:35248211. IF:35,7 (Q1/1D). Document type: Letter.
Molero X, Ayuso JR, Balsells J, Boadas J, Busquets J, Casteras A, Concepcion M, Cuatrecasas M, Esparrach GF, Fort E, Borobia FG, Gines A, Ilzarbe L, Loras C, Masachs M, Merino X, Olsina JJ, Puig V, Salord S, Serrano T, Vaquero EC. Chronic pancreatitis for the clinician. Part 1: Etiology and diagnosis. Interdisciplinary position paper of the Societat Catalana de Digestologia and the Societat Catalana de Pancrees. Gastroenterologia y Hepatologia. 2022; 45(3). DOI:10.1016/j.gastrohep.2021.05.017. PMID:34157366. IF:1,9 (Q4/9D). Document type: Article/Practice guideline.
Molero X, Ayuso JR, Balsells J, Boadas J, Busquets J, Casteràs A, Concepción M, Cuatrecasas M, Fernàndez G, Fort E, Garcia F, Ginès À, Ilzarbe L, Loras C, Masachs M, Merino X, Olsina JJ, Puig V, Salord S, Serrano T, Vaquero EC. Chronic pancreatitis for the clinician. Part 2: Treatment and follow-up. Interdisciplinary Position Paper of the Societat Catalana de Digestologia and the Societat Catalana de Pancrees. Gastroenterologia y Hepatologia. 2022; 45(4)DOI:10.1016/j.gastrohep.2021.05.016. PMID:34171422. IF:1,9 (Q4/9D). Document type: Article.
Montoro M, Cucala M, Lanas A, Villanueva C, Hervas AJ, Alcedo J, Gisbert JP, Aisa AP, Bujanda L, Calvet X, Mearin F, Murcia O, Canelles P, Lopez SG, de Argila CM, Planella M, Quintana M, Jerico C, Erce J, Spanish Assoc Gastroenterology A. Indications and hemoglobin thresholds for red blood cell transfusion and iron replacement in adults with gastrointestinal bleeding: An algorithm proposed by gastroenterologists and patient blood management experts. Frontiers in Medicine. 2022; 9:903739. DOI:10.3389/fmed.2022.903739. PMID:36186804. IF:3,9 (Q2/4D). Document type: Review.
Riba F, Guarner C, Solanes M, Francia E, Garcia P, Machlab S, Mascort J, Mendive JM, Ortiz J, Calvet X. Indications and risk assessment of endoscopic examinations in elderly or frail people. Position paper of the Societat Catalana de Digestologia, the Societat Catalana de Geriatria i Gerontologia and the Societat Catalana de Medicina de Familia i Comunitaria. Gastroenterologia y Hepatologia. 2022; 45(10). DOI:10.1016/j.gastrohep.2022.03.004. PMID:35278501. IF:1,9 (Q4/9D). Document type: Article/Practice guideline.
Riestra S, Taxonera C, Zabana Y, Carpio D, Chaparro M, Barrio J, Rivero M, Lopez A, Esteve M, de Francisco R, Bastida G, Garcia S, Manosa M, Martin MD, Perez JL, Guardiola J, Munoz F, Arranz L, Cabriada JL, Garcia MF, Navarro M, Montoro MA, Ricart E, Bermejo F, Calvet X, Piqueras M, Garcia E, Marquez L, Minguez M, Van M, Bujanda L, Aldeguer X, Sicilia B, Iglesias E, Alcain G, Perez I, Rolle V, Castano A, Gisbert JP, Domenech E, G. Performance of Screening Strategies for Latent Tuberculosis Infection in Patients with Inflammatory Bowel Disease: Results from the ENEIDA Registry of GETECCU. Journal of Clinical Medicine. 2022; 11(13):3915. DOI:10.3390/jcm11133915. PMID:35807201. IF:3,9 (Q2/4D). Document type: Article.
Rivero L, Gavric A, Herrero J, Remedios D, Alvarez V, Albeniz E, Gordillo J, Puig I, Lopez J, Huerta A, Lopez M, Salces I, Penas B, Parejo S, Rodriguez E, Herraiz M, Carretero C, Gimeno AZ, Saperas E, Alvarez C, Arnau C, Ortiz O, Sanchez A, Jung G, Balaguer F, Pellise M. The «diagnose and leave in» strategy for diminutive rectosigmoid polyps in Lynch syndrome: a post hoc analysis from a randomized controlled trial. ENDOSCOPY. 2022; 54(01). DOI:10.1055/a-1328-5405. PMID:33271604. IF:9,3 (Q1/1D). Document type: Article.
Román E, De Francisco S, Ramos A, Ricart MT, Santesmases R, Hernández E, Campillo B, Torres A, Baciero C, Guillaumet M, Serret M, Abades M and San José A. SARS-CoV2 Infection among Nursing Students. Prospective Study. International Journal of Nursing and Health Care Research. 5: 311. DOI:10.29011/2688-9501.101311. Document type: Article.
Romero C, Gonzalez C, Hernandez P, Garcia E. Usefulness of capsule endoscopy in idiopathic complex perianal disease. Gastroenterologia y Hepatologia. 2022; 45(10). DOI:10.1016/j.gastrohep.2022.03.010. PMID:35489586. IF:1,9 (Q4/9D). Document type: Letter.
Sánchez R, Subtil JC, Martínez B, Gornals J, Guarner C, Repiso A, Peralta S, Aparicio JR, Rodríguez de Santiago E, Bazaga S, Juzgado D, González F, Albillos A, Vázquez E. EUS-guided gastroenterostomy versus duodenal self-expandable metal stent for malignant gastric outlet obstruction: results from a nationwide multicenter retrospective study (with video). GASTROINTESTINAL ENDOSCOPY. 2022; 96(6). DOI:10.1016/j.gie.2022.07.018. PMID:35870508. IF:7,7 (Q1/2D). Document type: Article.
Semmler G, Lens S, Meyer EL, Baiges A, Alvardo E, Llop E, Tellez L, Schwabl P, Mauro E, Escudé L, Díez C, Ibañez L, Puente Á, Fortea JI, Abadía M, Zanetto A, Conthe A, Hernandez H, Luzko IS, Jia J, Yoshiji H, Francque SM, Tsochatzis EA, Russo FP, Crespo G, Forns X, Bañares R, Villanueva C, Hernández V, Reiberger T, Bosch J, García JC, Mandorfer M, A study BY. Non-invasive tests for clinically significant portal hypertension after HCV cure. JOURNAL OF HEPATOLOGY. 2022; 77(6)DOI:10.1016/j.jhep.2022.08.025. PMID:36063968. IF:25,7 (Q1/1D). Document type: Article.
Soriano G, Sánchez E, Poca M, Román E, Guarner Aguilar C. Empleo de probióticos en hepatología. En: Microbiota, probióticos y prebióticos. Evidencia científica. Eds: Guillermo Álvarez Calatayud, Francisco Guarner Aguilar. Sociedad Española de Microbiota, Probióticos y Prebióticos. ERGON, Barcelona 2022, págs. 659-667. ISBN 9788418576492 SKU: 978-84-18576-49-2. Document type: Book chapter.
Ventura M, Argemi J, Jones PD, Lackner C, El Hag M, Abraldes JG, Alvarado E, Clemente A, Ravi S, Alves A, Alboraie M, Altamirano J, Barace S, Bosques F, Brown R, Caballeria J, Cabezas J, Carvalhana S, Cortez H, Costa A, Degre D, Fernandez C, Ganne N, Garcia G, Genesca J, Koskinas J, Lanthier N, Louvet A, Lozano JJ, Lucey MR, Masson S, Mathurin P, Mendez N, et al. [Szafranska J, Villanueva C]. Clinical, histological and molecular profiling of different stages of alcohol-related liver disease. GUT. 2022; 71(9):324295. DOI:10.1136/gutjnl-2021-324295. PMID:34992134. IF:24,5 (Q1/1D). Document type: Article.
Villanueva C, Torres F, Sarin SK, Shah HA, Tripathi D, Brujats A, Rodrigues SG, Bhardwaj A, Azam Z, Hayes PC, Jindal A, Abid S, Alvarado E, Bosch J, Carvedilol IPD MA GRP, Baveno Cooperation EASL C. Carvedilol reduces the risk of decompensation and mortality in patients with compensated cirrhosis in a competing-risk meta-analysis. JOURNAL OF HEPATOLOGY. 2022; 77(4). DOI:10.1016/j.jhep.2022.05.021. PMID:35661713. IF:25,7 (Q1/1D). Document type: Article.
Zabana Y, Marin I, Rodriguez I, Vera I, Martin MD, Guerra I, Gisbert JP, Mesonero F, Benitez O, Taxonera C, Ponferrada A, Piqueras M, Lucendo AJ, Caballol B, Manosa M, Martinez P, Bosca M, Gordillo J, Bujanda L, Mancenido N, Martinez T, Lopez A, Rodriguez C, Garcia S, Vega P, Rivero M, Melcarne L, Calvo M, Iborra M, de MB, Sicilia B, Barrio J, Perez JL, et al. [Bertoletti F]. Nationwide COVID-19-EII Study: Incidence, Environmental Risk Factors and Long-Term Follow-Up of Patients with Inflammatory Bowel Disease and COVID-19 of the ENEIDA Registry. Journal of Clinical Medicine. 2022; 11(2):421. DOI:10.3390/jcm11020421. PMID:35054116. IF:3,9 (Q2/4D). Document type: Article.
Zabana Y, Marin I, Rodriguez I, Vera I, Martin MD, Guerra I, Gisbert JP, Mesonero F, Benitez O, Taxonera C, Ponferrada A, Piqueras M, Lucendo AJ, Caballol B, Manosa M, Martinez P, Bosca M, Gordillo J, Bujanda L, Mancenido N, Martinez T, Lopez A, Rodriguez C, Garcia S, Vega P, Rivero M, Melcarne L, Calvo M, Iborra M, de Acosta MB, Sicilia B, Barrio J, Calle JLP, et al. [Bertoletti F]. Risk Factors for COVID-19 in Inflammatory Bowel Disease: A National, ENEIDA-Based Case-Control Study (COVID-19-EII). Journal of Clinical Medicine. 2022; 11(24):7540. DOI:10.3390/jcm11247540. PMID:36556155. IF:3,9 (Q2/4D). Document type: Article.

Publicaciones 2021

Albeniz E, Enguita M, Gimeno AZ, de Tejada AH, Nogales O, Espinos JC, Sanchez JR, Roson P, Guarner C, Marin JC, Bhandari P, Spadaccini M, Repici A, Hassan C, Alvarez MA, Beroiz BI. The Answer to «When to Clip» After Colorectal Endoscopic Mucosal Resection Based on a Cost-Effectiveness Analysis. AMERICAN JOURNAL OF GASTROENTEROLOGY. 2021; 116(2). DOI:10.14309/ajg.0000000000000943. PMID:33149001. IF:12,045.
Algaba A, Guerra I, Ricart E, Iglesias E, Mañosa M, Gisbert JP, Guardiola J, Mínguez M, Castro B, de Francisco R, Nos P, Bertoletti F, Mesonero F, Barrio J, Martín-Arranz MD, Calvet X, García-López S, Sicilia B, Alcaín G, Esteve M, Márquez L, Piqueras M, Jiménez L, Perez-Calle JL, Bujanda L, García-Sepulcre M, Fernández A, Moraleja I, Lorente RH, Et al.; Spanish GETECCU Group (ENEIDA Project). Extraintestinal Manifestations in Patients with Inflammatory Bowel Disease: Study Based on the ENEIDA Registry. DIGESTIVE DISEASES AND SCIENCES. 2021;66(6):2014-2023. DOI:10.1007/s10620-020-06424-x. PMID: 32671587. IF:3,487.
Ampuero J, Aller R, Gallego R, Crespo J, Abad J, Gonzalez A, Gomez J, Caballeria J, Lo Iacono O, Ibanez L, Garcia J, Martin R, Frances R, Fernandez C, Diago M, Soriano G, Andrade RJ, Latorre R, Jorquera F, Morillas RM, Escudero D, Estevez P, Hernandez M, Augustin S, Pareja MJ, Banales JM, Aspichueta P, Benlloch S, Rosales JM, Salmeron J, Turnes J, Romero M. Definite and indeterminate nonalcoholic steatohepatitis share similar clinical features and prognosis: A longitudinal study of 1893 biopsy-proven nonalcoholic fatty liver disease subjects. LIVER INTERNATIONAL. 2021; 41(9). DOI:10.1111/liv.14898. PMID:33896100. IF:8,754.
Arab JP, Diaz LA, Baeza N, Idalsoaga F, Fuentes E, Arnold J, Ramirez CA, Morales D, Ventura M, Alvarado E, Zhang W, Clark V, Simonetto D, Ahn JC, Buryska S, Mehta TI, Stefanescu H, Horhat A, Bumbu A, Dunn W, Attar B, Agrawal R, Haque ZS, Majeed M, Cabezas J, Garcia I, Parker R, Cuyas B, Poca M, Soriano G, Sarin SK, Maiwall R, Jalal PK, Abdulsada S, et al. Identification of optimal therapeutic window for steroid use in severe alcohol-associated hepatitis: A worldwide study. JOURNAL OF HEPATOLOGY. 2021; 75(5). DOI:10.1016/j.jhep.2021.06.019. PMID:34166722. IF:30,083.
Arroyo JA, Julve J, Vlacho B, Corcoy R, Ponte P, Roman E, Navas E, Llaurado G, Franch J, Domingo P, Mauricio D. Previous Vitamin D Supplementation and Morbidity and Mortality Outcomes in People Hospitalised for COVID19: A Cross-Sectional Study. Frontiers in Public Health. 2021; 9:758347. DOI:10.3389/fpubh.2021.758347. PMID:34631653. IF:6,461.
Calafat M, Gonzalez C, Fortuny M, Roig C, Calm A, Mombiela A, Canete F, Bertoletti F, Gonzalez L, Teller M, Gordillo J, Manosa M, Garcia E, Domenech E. Impact of immunosuppressants on SARS-CoV-2 infection in elderly patients with inflammatory bowel disease. AGING CLINICAL AND EXPERIMENTAL RESEARCH. 2021; 33(8). DOI:10.1007/s40520-021-01917-9. PMID:34164799. IF:4,481.
Casanova MJ, Chaparro M, Nantes O, Benitez JM, Rojas M, Castro J, Huguet JM, Martin A, Aicart M, Tosca J, Martin MD, Gonzalez C, Manosa M, Leo E, Lamuela LJ, Perez I, Bujanda L, Hinojosa J, Pajares R, Arguelles F, Perez JL, Rodriguez GE, Guardiola J, Barreiro M, Gisbert JP. Clinical outcome after anti-tumour necrosis factor therapy discontinuation in 1000 patients with inflammatory bowel disease: the EVODIS long-term study. ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2021; 53(12). DOI:10.1111/apt.16361. PMID:33962482. IF:9,524.
Chaparro M, Garre A, Iborra M, Sierra M, Barreiro M, Fernandez A, de Castro L, Bosca M, Casanova MJ, Lopez A, Lorente R, Rodriguez C, Carbajo AY, Arroyo MT, Gutierrez A, Hinojosa J, Martinez T, Villoria A, Bermejo F, Busquets D, Camps B, Canete F, Mancenido N, Monfort D, Navarro M, Perez JL, Ramos L, Rivero M, Angueira T, et al. [Gonzalez C, Garcia E]. Effectiveness and Safety of Ustekinumab in Ulcerative Colitis: Real-world Evidence from the ENEIDA Registry. Journal of Crohns & Colitis. 2021; 15(11). DOI:10.1093/ecco-jcc/jjab070. PMID:33860795. IF:10,020.
Chaparro M, Garre A, Mesonero F, Rodriguez C, Barreiro M, Martinez J, Arroyo MT, Mancenido N, Sierra M, Vera I, Casanova MJ, Nos P, Gonzalez C, Martinez T, Bosca M, Calafat M, Busquets D, Girona E, Llao J, Martin MD, Piqueras M, Ramos L, Suris G, Bermejo F, Carbajo AY, Casas D, Fernandez A, Garcia MJ, Ginard D, Gutierrez A, Hernandez L, et al. Tofacitinib in Ulcerative Colitis: Real-world Evidence From the ENEIDA Registry. Journal of Crohns & Colitis. 2021; 15(1). DOI:10.1093/ecco-jcc/jjaa145. PMID:32969471. IF:10,020.
Chaparro M, Garre A, Ortiz AN, Palomares MTDL, Rodriguez C, Riestra S, Vela M, Benitez JM, Salgado EF, Rodriguez ES, Hernandez V, Ferreiro R, Diaz AP, Barrio J, Huguet JM, Sicilia B, Martin MD, Calvet X, Ginard D, Alonso I, Fernandez L, Trastoy PV, Rivero M, Vera I, Vega P, Navarro P, Sierra M, Cabriada JL, Aguas M, Vicente R, Navarro M, Echarri A, et al. [Gordillo J]. Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study. Journal of Clinical Medicine. 2021; 10(13):2885. DOI:10.3390/jcm10132885. PMID:34209680. IF:4,964.
de Paredes A, Villanueva C, Blanco C, Genesca J, Manicardi N, Garcia JC, Calleja JL, Aracil C, Morillas RM, Poca M, Penas B, Augustin S, Abraldes JG, Alvarado E, Royo F, Garcia ML, Falcon JM, Banares R, Bosch J, Gracia J, Albillos A. Serum miR-181b-5p predicts ascites onset in patients with compensated cirrhosis. Jhep Reports. 2021; 3(6):100368. DOI:10.1016/j.jhepr.2021.100368. PMID:34712934. IF:9,917.
Fernandez C, Alvarez M, Quintana I, Lopez A, Amigo J, Cameselle JM, Roman E, Gonzalez D, Llor X, Bujanda L, Bessa X, Jover R, Balaguer F, Castells A, Castellvi S, Capella G, Carracedo A, Valle L, Ruiz C. Exome sequencing of early-onset patients supports genetic heterogeneity in colorectal cancer. Scientific Reports. 2021; 11(1):11135. DOI:10.1038/s41598-021-90590-z. PMID:34045552. IF:4,996.
Garcia A, Loras C, Guarner C, Velasquez JG, Andujar X, Salord S, Busquets J, Tebe C, Laquente B, Gornals JB. Is a coaxial plastic stent within a lumen-apposing metal stent useful for the management of distal malignant biliary obstruction?. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES. 2021; 35(8). DOI:10.1007/s00464-021-08435-9. PMID:33721090. IF:3,453.
Gil A, Ampuero J, Rojas A, Gallego R, Munoz R, Rico MC, Millan R, Garcia R, Frances R, Soriano G, Romero M. Development and Validation of a Clinical-Genetic Risk Score to Predict Hepatic Encephalopathy in Patients With Liver Cirrhosis. AMERICAN JOURNAL OF GASTROENTEROLOGY. 2021; 116(6). DOI:10.14309/ajg.0000000000001164. PMID:33852451. IF:12,045.
Hernandez E, Santesmases R, Roman E, Porcel MA, Busquet AT, Perez MB, Verdu J. Prevalence and characteristics of older people with pressure ulcers and legs ulcers, in nursing homes in Barcelona. Journal of Tissue Viability. 2021; 30(1). DOI:10.1016/j.jtv.2021.01.003. PMID:33485786. IF:3,374.
Julia A, Martinez SH, Domenech E, Canete JD, Ferrandiz C, Tornero J, Gisbert JP, Fernandez A, Dauden E, Barreiro M, Perez C, Queiro R, Lopez FJ, Carazo JLS, Mendoza JL, Alperi M, Montilla C, Venegas JJP, Munoz F, Castaneda S, Lasanta ML, Marsal S, Fonseca E, Rodriguez J, Carreira P, Garcia V, Pinto JA, Puig L, Ricart E, Blanco F, Gratacos J, et al. [Garcia E, Diaz C]. Food groups associated with immune-mediated inflammatory diseases: a Mendelian randomization and disease severity study. EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2021; 75(9). DOI:10.1038/s41430-021-00913-6. PMID:33893449. IF:4,884.
Llao J, Masnou H, Romero C, Bargallo A, Gely C, Manosa M, Gordillo J, Garcia E, Domenech E. Noninvasive assessment of liver fibrosis in Crohn’s disease patients exposed to methotrexate. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY. 2021; 33(6). DOI:10.1097/MEG.0000000000001799. PMID:32804842. IF:2,586.
Martinez J, Hernandez V, Rodriguez E, Tellez L, Procopet B, Giraldez A, Amitrano L, Villanueva C, Thabut D, Ibanez L, Silva G, Genesca J, Bureau C, Trebicka J, Banares R, Krag A, Llop E, Laleman W, Palazon JM, Castellote J, Rodrigues S, Gluud LL, Noronha C, Canete N, Rodriguez M, Ferlitsch A, Schwarzer R, Mundi JL, Gronbaek H, Hernandez M, et al. [Alvarado E]. Bacterial infections in patients with acute variceal bleeding in the era of antibiotic prophylaxis. JOURNAL OF HEPATOLOGY. 2021; 75(2). DOI:10.1016/j.jhep.2021.03.026. PMID:33845059. IF:30,083.
Massey V, Parrish A, Argemi J, Moreno M, Mello A, Garcia M, Altamirano J, Odena G, Dubuquoy L, Louvet A, Martinez C, Adrover A, Affo S, Morales O, Sancho P, Millan C, Alvarado E, Morales D, Caballeria J, Mann J, Cao S, Sun ZL, Shah V, Cameron A, Mathurin P, Snider N, Villanueva C, Morgan TR, Guinovart J, Vadigepalli R, Bataller R. Integrated Multiomics Reveals Glucose Use Reprogramming and Identifies a Novel Hexokinase in Alcoholic Hepatitis. GASTROENTEROLOGY. 2021; 160(5). DOI:10.1053/j.gastro.2020.12.008. PMID:33309778. IF:33,883.
Mesonero F, Castro J, Benitez JM, Camps B, Iborra M, Lopez A, Torres P, Esteve M, Tosca J, Bertoletti F, Almela P, Calvet X, Vera I, Bujanda L, Gomollon F, Rodriguez C, Antolin B, Busquets D, Hernandez A, Rivero M, Miquel D, Castano A, Gisbert JP, Domenech E, Lopez A. Effectiveness and safety of methotrexate monotherapy in patients with Crohn’s disease refractory to anti-TNF-alpha: results from the ENEIDA registry. ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2021; 53(9). DOI:10.1111/apt.16315. PMID:33715177. IF:9,524.
Nicoara O, Han GH, Rudler M, Angrisani D, Monescillo A, Torres F, Casanovas G, Bosch J, Lv Y, Thabut D, Fan DM, Hernandez V, Garcia JC, Alvarado E, Ripoll C. Effects of Early Placement of Transjugular Portosystemic Shunts in Patients With High-Risk Acute Variceal Bleeding: a Meta-analysis of Individual Patient Data. GASTROENTEROLOGY. 2021; 160(1). DOI:10.1053/j.gastro.2020.09.026. PMID:32980344. IF:33,883.
Perea L, Rodriguez L, Nieto JC, Zamora C, Canto E, Soriano G, Poca M, Blanco P, Navarro F, Muniesa M, Vidal S. Bacteriophages immunomodulate the response of monocytes. EXPERIMENTAL BIOLOGY AND MEDICINE. 2021; 246(11). DOI:10.1177/1535370221995154. PMID:33641443. IF:4,088.
Reig A, Alvarez C, Vergara M, Gomez E, Gallego A, Perez IM, Fabrega E, Hernandez M, Berenguer M, Estevez P, Arencibia A, Morillas RM, Horta D, Albillos A, Casado M, De la Cruz G, Fernandez E, Molina E, Hijona L, Diago M, Fernandez CM, Gonzalez JM, Sala M, Gomez J, Romero M, Suarez F, Vargas V, Ferre C, Andrade RJ, Chahri N, Pares A. Obeticholic Acid and Fibrates in Primary Biliary Cholangitis: Comparative Effects in a Multicentric Observational Study. AMERICAN JOURNAL OF GASTROENTEROLOGY. 2021; 116(11). DOI:10.14309/ajg.0000000000001343. PMID:34158466. IF:12,045.
Rodríguez de Santiago E, Shimamura Y, Pioche M, Eleftheriadis N, Albéniz E, Bechara R, Yan Chiu PW, Guarner-Argente C, Herreros de Tejada A, Uchima H, Fujiyoshi Y, Ponchon T, González-Gete G, Hew S, Murzi-Pulgar M, Matallana V, Parejo-Carbonell S, Estremera-Arévalo F, Moll F, Onimaru M, Inoue H. Safety and effectiveness of peroral endoscopic myotomy in patients on antiplatelet or anticoagulant therapy: an international multicenter case-control study. GASTROINTESTINAL ENDOSCOPY. 2021;93(4):839-849. DOI:10.1016/j.gie.2020.07.030. PMID: 32717366. IF:10,396.
Román E, Parramón M, Flavià M, Gely C, Poca M, Gallego A, Santesmases R, Hernández E, Nieto JC, Urgell E, Alvarado-Tapias E, Vidal S, Ferrero-Gregori A, Vargas V, Guarner C, Soriano G. Frailty in outpatients with cirrhosis: A prospective observational study. Liver International. 2021;41(2):357-368. DOI:10.1111/liv.14694. PMID: 33030788. IF:8,754.
Roman E, Poca M, Amoros G, Rosell J, Gely C, Nieto JC, Vidal S, Urgell E, Ferrero A, Alvarado E, Cuyas B, Hernandez E, Santesmases R, Guarner C, Escorsell A, Soriano G. Phase angle by electrical bioimpedance is a predictive factor of hospitalisation, falls and mortality in patients with cirrhosis. Scientific Reports. 2021; 11(1):20415. DOI:10.1038/s41598-021-99199-8. PMID:34650096. IF:4,996.
Stephens C, Robles M, Medina I, Garcia M, Ortega A, Sanabria J, Gonzalez A, Alvarez I, Slim M, Jimenez M, Gonzalez R, Fernandez MC, Casado M, Soriano G, Roman E, Hallal H, Romero M, Castiella A, Conde I, Prieto M, Moreno JM, Giraldez A, Moreno JM, Kaplowitz N, Lucena MI, Andrade RJ, Participating CTR. Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry. JOURNAL OF HEPATOLOGY. 2021; 75(1). DOI:10.1016/j.jhep.2021.01.029. PMID:33539847. IF:30,083.
Trebicka J, Fernandez J, Papp M, Caraceni P, Laleman W, Gambino C, Giovo I, Uschner FE, Jansen C, Jimenez C, Mookerjee R, Gustot T, Albillos A, Banares R, Jarcuska P, Steib C, Reiberger T, Acevedo J, Gatti P, Shawcross DL, Zeuzem S, Zipprich A, Piano S, Berg T, Bruns T, Danielsen KV, Coenraad M, Merli M, Stauber R, Zoller H, et al. [Soriano G, Alvarado E]. PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis. JOURNAL OF HEPATOLOGY. 2021; 74(5). DOI:10.1016/j.jhep.2020.11.019. PMID:33227350. IF:30,083.
Ventura M, Simon M, Poca M, Ariza X, Masnou H, Sanchez J, Llop E, Canete N, Martin M, Amador A, Martinez J, Clemente A, Puente A, Torrens M, Alvarado E, Napoleone L, Miquel M, Ardevol A, Rodrigo MC, Calleja JL, Sole C, Soriano G, Genesca J. Effects of Albumin on Survival after a Hepatic Encephalopathy Episode: Randomized Double-Blind Trial and Meta-Analysis. Journal of Clinical Medicine. 2021; 10(21):4885. DOI:10.3390/jcm10214885. PMID:34768404. IF:4,964.
Villanueva C, Albillos A, Genesca J, Garcia JC, Brujats A, Calleja JL, Aracil C, Banares R, Morillas RM, Poca M, Penas B, Augustin S, Abraldes JG, Alvarado E, Torres F, Bosch J. Bacterial infections adversely influence the risk of decompensation and survival in compensated cirrhosis. JOURNAL OF HEPATOLOGY. 2021; 75(3). DOI:10.1016/j.jhep.2021.04.022. PMID:33905794. IF:30,083.
Weersink RA, Alvarez-Alvarez I, Medina-Cáliz I, Sanabria-Cabrera J, Robles-Díaz M, Ortega-Alonso A, García-Cortés M, Bonilla E, Niu H, Soriano G, Jimenez-Perez M, Hallal H, Blanco S, Kaplowitz N, Lucena MI, Andrade RJ, [Antonijoan R, Gonzalez-Gallego J]. Clinical Characteristics and Outcome of Drug-Induced Liver Injury in the Older Patients: From the Young-Old to the Oldest-Old. CLINICAL PHARMACOLOGY & THERAPEUTICS. 2021;109(4):1147-1158. DOI:10.1002/cpt.2108. PMID: 33179256. IF:6,903.

MEDICINA TRANSLACIONAL

Patología Digestiva

Principales líneas de investigación

Investigación experimental

Investigación clínica

Retos

Coordinación del grupo

Miembros

Publicaciones 2022

Publicaciones 2021

Principales líneas de investigación

Investigación experimental

Investigación clínica

Retos

Coordinación del grupo

Miembros

Publicaciones 2022

Publicaciones 2021

Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau