Cercar
01/11/2025
Temporal associations of neuropsychiatric symptoms, demographics and amyloid with subsequent tau burden in older adults
Aguilar-Dominguez, P, Palpatzis, E, Akinci, M, Canal-Garcia, A, Pereira, JB, Bejanin, A, Arenaza-Urquijo, EM. Temporal associations of neuropsychiatric symptoms, demographics and amyloid with subsequent tau burden in older adults. JPAD-Journal of Prevention of Alzheimers Disease. 2025; 12(9)DOI:10.1016/j.tjpad.2025.100294. PMID:40750514. IF:7.800(Q1/1D).
01/10/2025
Diagnosis of Pulmonary Hypertension Associated With Lung Disease: A Call for Awareness
Castillo, D, Francesqui, J, Padilla, M, Montani, D. Diagnosis of Pulmonary Hypertension Associated With Lung Disease: A Call for Awareness. ARCHIVOS DE BRONCONEUMOLOGIA. 2025; 61(10)DOI:10.1016/j.arbres.2025.07.001. PMID:40681412. IF:9.200(Q1/1D).
27/09/2025
New landscape of the diagnosis of Alzheimer's disease
Frisoni, GB, Hansson, O, Nichols, E, Garibotto, V, Schindler, SE, van der Flier, WM, Jessen, F, Villain, N, Arenaza-Urquijo, EM, Crivelli, L, Fortea, J, Grinberg, LT, Ismail, Z, Minoshima, S, Ossenkoppele, R, Zetterberg, H, Petersen, RC, Dubois, B. New landscape of the diagnosis of Alzheimer's disease. LANCET. 2025; 406(10510)DOI:10.1016/S0140-6736(25)01294-2. PMID:40997838. IF:88.500(Q1/1D).
19/09/2025
Mitochondrial methylcytosines as blood-based biomarkers for Alzheimer's disease dementia prognosis
Gascón-Bayarri, J, Mosquera, JL, Blanch, M, Marti, P, Fontal, B, Trapero, C, Rojo, N, Rico, I, Campdelacreu, J, Fowler, C, Laws, SM, Tort-Merino, A, Sanchez-Valle, R, Bello, J, Fortea, J, Lleo, A, Mehanian, C, Swerdlow, RH, Reñe-Ramirez, R, Barrachina, M. Mitochondrial methylcytosines as blood-based biomarkers for Alzheimer's disease dementia prognosis. iScience. 2025; 28(9)DOI:10.1016/j.isci.2025.113418. PMID:40978150. IF:4.100(Q1/2D).
01/09/2025
Comment by European Alzheimer's Disease Consortium (EADC) investigators on the negative recommendation of the CHMP on the marketing authorization of donanemab for early Alzheimer' s disease
Jessen, F, Arbizu, J, Boada, M, Balasa, M, Bennys, K, Boban, M, Bürger, K, Chincarini, A, Cagnin, A, De Deyn, PP, Düzel, E, Engelborghs, S, Ewers, M, Exalto, LG, van der Flier, WM, Fortea, J, Frederiksen, KS, Frisoni, GB, Frölich, L, Garza-Martinez, AJ, Grimmer, T, Hanseeuw, B, Hort, J, Ivanoiu, A, Kehoe, PG, Kennelly, SP, Kern, S, Klöppel, S, Krajcovicová, L, Kramberger, MG, McGuinness, B, Mecocci, P, Oberstein, TJ, Ousset, PJ, Paquet, C, Perneczky, R, Piazza, F, Plantone, D, Rainero, I, Sacco, G, Salm, E, Santana, I, Scarmeas, N, Schneider, A, Schott, JM, Solje, E, Stefanova, E, Stögmann, E, Strauss, M, Sutovsky, S, Waldemar, G, Winblad, B. Comment by European Alzheimer's Disease Consortium (EADC) investigators on the negative recommendation of the CHMP on the marketing authorization of donanemab for early Alzheimer' s disease. JPAD-Journal of Prevention of Alzheimers Disease. 2025; 12(8)DOI:10.1016/j.tjpad.2025.100259. PMID:40640062. IF:7.800(Q1/1D).
01/09/2025
Down syndrome and Alzheimer's disease: insights into biomarkers, clinical symptoms, and pathology
Rafii, MS, Schlachetzki, Z, Barroeta, I, Head, E, Fortea, J, Ances, BM. Down syndrome and Alzheimer's disease: insights into biomarkers, clinical symptoms, and pathology. LANCET NEUROLOGY. 2025; 24(9)DOI:10.1016/S1474-4422(25)00237-6. PMID:40818475. IF:45.500(Q1/1D).
27/08/2025
Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia
Hok-A-Hin, YS, Vermunt, L, Peeters, CFW, van der Ende, EL, de Boer, SCM, Meeter, LH, de Houwer, J, Seelaar, H, van Swieten, JC, Hu, WT, Lleó, A, Alcolea, D, Engelborghs, S, Sieben, A, Chen-Plotkin, A, Irwin, DJ, van der Flier, WM, Pijnenburg, YAL, Teunissen, CE, del Campo, M. Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia. Molecular Neurodegeneration. 2025; 20(1)DOI:10.1186/s13024-025-00882-5. PMID:40866991. IF:17.500(Q1/1D).
26/08/2025
Comparison of the effectiveness of first-line preventive treatment of migraine in primary care: study protocol for a pragmatic clinical trial (PREMI study)
Giner-Soriano, M, Morros, R, Monfà, R, Ouchi, D, Fernández-García, S, Vedia, C, Monné, SB, Martínez, EMC, Fanlo, SC, Morollón, N, Nieto, RB, Delgado-Espinoza, CE, García-Sangenís, A. Comparison of the effectiveness of first-line preventive treatment of migraine in primary care: study protocol for a pragmatic clinical trial (PREMI study). Trials. 2025; 26(1)DOI:10.1186/s13063-025-08961-0. PMID:40859286. IF:2.000(Q3/7D).
21/08/2025
Regional associations between cerebrovascular disease and cholinergic white matter pathways in the Lewy body continuum
Rennie, A, Nemy, M, Jerele, C, Rodríguez-Baz, I, Montal, V, Bejanin, A, Kramberger, MG, Aarsland, D, Fortea, J, Lleó, A, Westman, E, Alcolea, D, Ferreira, D. Regional associations between cerebrovascular disease and cholinergic white matter pathways in the Lewy body continuum. npj Parkinsons Disease. 2025; 11(1)DOI:10.1038/s41531-025-01118-5. PMID:40841717. IF:8.200(Q1/1D).
01/08/2025
Cerebrospinal fluid lipoprotein-mediated cholesterol delivery to neurons is impaired in Alzheimer's disease and involves APOE4
Borràs, C, Canyelles, M, Santos, D, Rotllan, N, Núñez, E, Vàzquez, J, Maspoch, D, Cano-Sarabia, M, Zhao, Q, Carmona-Iragui, M, Sirisi, S, Lleó, A, Fortea, J, Alcolea, D, Blanco-Vaca, F, Escolà-Gil, JC, Tondo, M. Cerebrospinal fluid lipoprotein-mediated cholesterol delivery to neurons is impaired in Alzheimer's disease and involves APOE4. JOURNAL OF LIPID RESEARCH. 2025; 66(8)DOI:10.1016/j.jlr.2025.100865. PMID:40701521. IF:4.100(Q2/4D).
01/08/2025
Genetic architecture of FTLD-TDP pathological subtypes
Dols-Icardo, O, Reus, LM, Ramirez, A. Genetic architecture of FTLD-TDP pathological subtypes. TRENDS IN NEUROSCIENCES. 2025; 48(8)DOI:10.1016/j.tins.2025.06.005. PMID:40610249. IF:15.100(Q1/1D).
22/07/2025
Machine learning in Alzheimer's disease genetics
Bracher-Smith, M, Melograna, F, Ulm, B, Bellenguez, C, Grenier-Boley, B, Duroux, D, Nevado, AJ, Holmans, P, Tijms, BM, Hulsman, M, de Rojas, I, Campos-Martin, R, van der Lee, S, Castillo, A, Küçükali, F, Peters, O, Schneider, A, Dichgans, M, Rujescu, D, Scherbaum, N, Deckert, J, Riedel-Heller, S, Hausner, L, Molina-Porcel, L, Düzel, E, Grimmer, T, Wiltfang, J, Heilmann-Heimbach, S, Moebus, S, Tegos, T, Scarmeas, N, Dols-Icardo, O, Moreno, F, Pérez-Tur, J, Bullido, MJ, Pastor, P, Sánchez-Valle, R, Alvarez, V, Boada, M, García-González, P, Puerta, R, Mir, P, Real, LM, Piñol-Ripoll, G, García-Alberca, JM, Rodriguez-Rodriguez, E, Soininen, H, Heikkinen, S, de Mendonça, A, Mehrabian, S, Traykov, L, Hort, J, Vyhnalek, M, Sandau, N, Thomassen, JQ, Pijnenburg, YAL, Holstege, H, van Swieten, J, Ramakers, I, Verhey, F, Scheltens, P, Graff, C, Papenberg, G, Giedraitis, V, Williams, J, Amouyel, P, Boland, A, Deleuze, JF, Nicolas, G, Dufouil, C, Pasquier, F, Hanon, O, Debette, S, Grünblatt, E, Popp, J, Ghidoni, R, Galimberti, D, Arosio, B, Mecocci, P, Solfrizzi, V, Parnetti, L, Squassina, A, Tremolizzo, L, Borroni, B, Wagner, M, Nacmias, B, Spallazzi, M, Seripa, D, Rainero, I, Daniele, A, Piras, F, Masullo, C, Rossi, G, Jessen, F, Kehoe, P, Magda, T, Sánchez-Juan, P, Sleegers, K, Ingelsson, M, Hiltunen, M, Sims, R, van der Flier, W, Andreassen, OA, Ruiz, A, Ramirez, A, Frikke-Schmidt, R, Amin, N, Roshchupkin, G, Lambert, JC, Van Steen, K, van Duijn, C, Escott-Price, V. Machine learning in Alzheimer's disease genetics. Nature Communications. 2025; 16(1)DOI:10.1038/s41467-025-61650-z. PMID:40691194. IF:15.700(Q1/1D).
01/07/2025
Risk for SARS-Cov2 Cell Entry Through ACE2 and TMPRSS2 is Not Increased in Alzheimer's Disease, Concerns About Down Syndrome
Saez-Valero, J, Granados, CA, Lennol, MP, Garcia-Ayllón, MS, Zetterberg, H, Blennow, K, Fortea, J. Risk for SARS-Cov2 Cell Entry Through ACE2 and TMPRSS2 is Not Increased in Alzheimer's Disease, Concerns About Down Syndrome. JOURNAL OF NEUROCHEMISTRY. 2025; 169DOI:. PMID:. IF:4.000(Q2/3D).
01/01/2025
Towards the Discovery of Down Syndrome Brain Biomarkers Using Generative Models
Malé, J, Fortea, J, Aranha, MR, Heuzé, Y, Martínez-Abadías, N, Sevillano, X. Towards the Discovery of Down Syndrome Brain Biomarkers Using Generative Models. Computer Vision-Eccv 2024 Workshops, Pt Xvi. 2025; 15638DOI:10.1007/978-3-031-91721-9_13. PMID:. IF:(Q/D).
01/01/2025
Sleep-related changes in astrocytic biomarkers are modulated by APOE e4 genotype in cognitively unimpaired adults
Zhu, NL, Altuna, M, Arranz, J, Rodriguez-Baz, I, Sanchez-Saudinos, MB, Videla, L, Valldeneu, S, Carrera-Vega, M, Romero, S, Fortea, J, Lleo, A, Giménez, S, Alcolea, D. Sleep-related changes in astrocytic biomarkers are modulated by APOE e4 genotype in cognitively unimpaired adults. Brain Communications. 2025; 7(6)DOI:10.1093/braincomms/fcaf437. PMID:41268178. IF:(Q/D).
05/03/2024
Developmental outcome of electroencephalographic findings in SYNGAP1 encephalopathy
Ribeiro-Constante, J, Tristán-Noguero, A, Calvo, FFM, Ibañez-Mico, S, Segura, JLP, Ramos-Fernández, JM, Chicano, MDM, Leon, RC, Insuga, VS, Alguacil, EG, Davila, CV, Fernández-Jaén, A, Plans, L, Camacho, A, Visa-Reñé, N, Blazquez, MDMT, Paredes-Carmona, F, Marti-Carrera, I, Hernández-Fabián, A, Davi, MT, Sanchez, MC, Herraiz, LC, Pita, PF, Gonzalez, TB, O'Callaghan, M, Santa Polonia, FFI, Cazorla, MR, Lucas, MTF, González-Meneses, A, Sala-Coromina, J, Macaya, A, Lasa-Aranzasti, A, Cueto-González, AM, Parraga, FV, Plana, JC, Serrano, M, Alonso, X, Del Castillo-Berges, D, Schwartz-Palleja, M, Illescas, S, Camacho, AR, Capdevila, OS, García-Cazorla, A, Bayés, A, Alonso-Colmenero, I. Developmental outcome of electroencephalographic findings in SYNGAP1 encephalopathy. Frontiers in Cell and Developmental Biology. 2024; 12DOI:10.3389/fcell.2024.1321282. PMID:38505260. IF:4.300(Q1/1D).
09/01/2024
Tetrahydrobiopterin (BH4) treatment stabilizes tyrosine hydroxylase: Rescue of tyrosine hydroxylase deficiency phenotypes in human neurons and in a knock-inmouse model
Jung-Kc, K, Tristán-Noguero, A, Altankhuyag, A, Belenguer, DP, Prestegård, KS, Fernandez-Carasa, I, Baldeshi, AC, Bondarenko, MS, García-Cazorla, A, Consiglio, A, Martinez, A. Tetrahydrobiopterin (BH4) treatment stabilizes tyrosine hydroxylase: Rescue of tyrosine hydroxylase deficiency phenotypes in human neurons and in a knock-inmouse model. JOURNAL OF INHERITED METABOLIC DISEASE. 2024; 47(3)DOI:10.1002/jimd.12702. PMID:38196161. IF:3.800(Q2/3D).
09/05/2023
Transcriptional diversity in specific synaptic gene sets discriminates cortical neuronal identity
Adam, AR, Martínez-López J.A., van der Spek, SJF, Sullivan, PF, Smit, AB, Hjerling-Leffler, J, Achsele, T, Andres-Alonso, M, Bagni, C, Bayes, A, Biederer, T, Brose, N, Chua, JJE, Coba, MP, Cornelisse, LN, de Juan-Sanz, J, Goldschmidt, HL, Gundelfinger, ED, Huganir, RL, Imig, C, Jahn, R, Jung, HJ, Kaeser, PS, Kim, E, Koopmans, F, Kreutz, MR, Lipstein, N, MacGillavry, HD, McPherson, PS, O'Connor, V, Pielot, R, Ryan, TA, Sala, C, Sheng, MR, Smalla, KH, Thomas, PD, Toonen, RF, van Weering, JRT, Verhage M., Verpelli, C. Transcriptional diversity in specific synaptic gene sets discriminates cortical neuronal identity. Biology Direct. 2023; 18(1)DOI:10.1186/s13062-023-00372-y. PMID:37161421. IF:5.700(Q1/1D).
21/04/2022
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Trubetskoy V., Pardiñas A.F., Qi T., Panagiotaropoulou G., Awasthi S., Bigdeli T.B., Chen C.-Y., Dennison C.A., Hall L.S., Lam M., Watanabe K., Frei O., Ge T., Harwood J.C., Magnusson S., Richards A.L., Sidorenko J., Wu Y., Zeng J., Grove J., Kim M., Li Z., Voloudakis G., Zhang W., Adams M., Agartz I., Atkinson E.G., Agerbo E., Al Eissa M., Albus M., Alexander M., Alizadeh B.Z., Alptekin K., Als T.D., Amin F., Arolt V., Arrojo M., Athanasiu L., Azevedo M.H., Bacanu S.A., Bass N.J., Begemann M., Belliveau R.A., Bene J., Benyamin B., Bergen S.E., Blasi G., Bobes J., Bonassi S., Braun A., Bressan R.A., Bromet E.J., Bruggeman R., Buckley P.F., Buckner R.L., Bybjerg-Grauholm J., Cahn W., Cairns M.J., Calkins M.E., Carr V.J., Castle D., Catts S.V., Chambert K.D., Chan R.C.K., Chaumette B., Cheng W., Cheung E.F.C., Chong S.A., Cohen D., Consoli A., Cordeiro Q., Costas J., Curtis C., Davidson M., Davis K.L., Degenhardt F., DeLisi L.E., Demontis D., Dickerson F., Dikeos D., Dinan T., Djurovic S., Duan J., Ducci G., Dudbridge F., Eriksson J.G., Fañanás L., Faraone S.V., Fiorentino A., Forstner A., Frank J., Freimer N.B., Frustaci A., Gadelha A., Genovese G., Gershon E.S., Giannitelli M., Giegling I., Giusti-Rodríguez P., Godard S., Goldstein J.I., González Peñas J., González-Pinto A., Gopal S., Gratten J., Green M.F., Greenwood T.A., Guillin O., Gülöksüz S., Gur R.E., Gur R.C., Gutiérrez B., Hahn E., Hakonarson H., Haroutunian V., Hartmann A.M., Harvey C., Hayward C., Henskens F.A., Herms S., Hoffmann P., Howrigan D.P., Ikeda M., Joa I., Julià A., Kähler A.K., Kam-Thong T., Kamatani Y., Karachanak-Yankova S., Kebir O., Keller M.C., Kelly B.J., Khrunin A., Kim S.-W., Klovins J., Kondratiev N., Konte B., Kraft J., Kubo M., Kucinskas V., Kucinskiene Z.A., Kusumawardhani A., Kuzelova-Ptackova H., Landi S., Lazzeroni L.C., Lee P.H., Legge S.E., Lehrer D.S., Lencer R., Lerer B., Lieberman J., Light G.A., Limborska S., Liu C.-M., Lönnqvist J., Loughland C.M., Lubinski J., Luykx J.J., Lynham A., Macek M., Jr, Mackinnon A., Magnusson P.K.E., Maher B.S., Maier W., Malaspina D., Mallet J., Marder S.R., Marsal S., Martin A.R., Martorell L., Mattheisen M., McCarley R.W., McDonald C., McGrath J.J., Medeiros H., Meier S., Melegh B., Melle I., Mesholam-Gately R.I., Metspalu A., Michie P.T., Milani L., Milanova V., Mitjans M., Molden E., Molina E., Molto M.D., Mondelli V., Moreno C., Morley C.P., Muntané G., Murphy K.C., Myin-Germeys I., Nenadic I., Nestadt G., Nikitina-Zake L., Noto C., Nuechterlein K.H., O’Brien N.L., O’Neill F.A., Oh S.-Y., Olincy A., Ota V.K., Pantelis C., Papadimitriou G.N., Parellada M., Paunio T., Pellegrino R., Periyasamy S., Perkins D.O., Pfuhlmann B., Pietiläinen O., Pimm J., Porteous D., Powell J.F., Quattrone D., Quested D., Radant A.D., Rampino A., Rapaport M.H., Rautanen A., Reichenberg A., Roe C., Roffman J.L., Roth J., Rothermundt M., Rutten B.P.F., Saker-Delye S., Salomaa V., Sanjuan J., Santoro M.L., Savitz A., Schall U., Scott R.J., Seidman L.J., Sharp S.I., Shi J., Siever L.J., Sigurdsson E., Sim K., Skarabis N., Slominsky P., So H.-C., Sobell J.L., Söderman E., Stain H.J., Steen N.E., Steixner-Kumar A.A., Stögmann E., Stone W.S., Straub R.E., Streit F., Strengman E., Stroup T.S., Subramaniam M., Sugar C.A., Suvisaari J., Svrakic D.M., Swerdlow N.R., Szatkiewicz J.P., Ta T.M.T., Takahashi A., Terao C., Thibaut F., Toncheva D., Tooney P.A., Torretta S., Tosato S., Tura G.B., Turetsky B.I., Üçok A., Vaaler A., Veijola J., Waddington J., Walter H., Waterreus A., Webb B.T., Weiser M., Williams N.M., Witt S.H., Wormley B.K., Wu J.Q., Xu Z., Yolken R., Zai C.C., Zhou W., Zhu F., Zimprich F., Atbasoglu E.C., Ayub M., Benner C., Bertolino A., Black D.W., Bray N.J., Breen G., Buccola N.G., Byerley W.F., Chen W.J., Cloninger C.R., Crespo-Facorro B., Donohoe G., Freedman R., Galletly C., Gandal M.J., Gennarelli M., Hougaard D.M., Hwu H.-G., Jablensky A.V., McCarroll S.A., Moran J.L., Mors O., Mortensen P.B., Müller-Myhsok B., Neil A.L., Nordentoft M., Pato M.T., Petryshen T.L., Pirinen M., Pulver A.E., Schulze T.G., Silverman J.M., Smoller J.W., Stahl E.A., Tsuang D.W., Vilella E., Wang S.-H., Xu S., Dai N., Wenwen Q., Agiananda F., Amir N., Antoni R., Arsianti T., Asmarahadi A., Diatri H., Djatmiko P., Irmansyah I., Khalimah S., Kusumadewi I., Kusumaningrum P., Lukman P.R., Nasrun M.W., Safyuni N.S., Prasetyawan P., Semen G., Siste K., Tobing H., Widiasih N., Wiguna T., Wulandari D., Evalina N., Hananto A.J., Ismoyo J.H., Marini T.M., Henuhili S., Reza M., Yusnadewi S., Abyzov A., Akbarian S., Ashley-Koch A., van Bakel H., Breen M., Brown M., Bryois J., Carlyle B., Charney A., Coetzee G., Crawford G., Dracheva S., Emani P., Farnham P., Fromer M., Galeev T., Gandal M., Gerstein M., Giase G., Girdhar K., Goes F., Grennan K., Gu M., Guerra B., Gursoy G., Hoffman G., Hyde T., Jaffe A., Jiang S., Jiang Y., Kefi A., Kim Y., Kitchen R., Lay F., Lee D., Li M., Liu C., Liu S., Mattei E., Navarro F., Pan X., Peters M.A., Pinto D., Pochareddy S., Polioudakis D., Purcaro M., Purcell S., Pratt H., Reddy T., Rhie S., Rozowsky J., Sanders S., Sestan N., Sethi A., Shi X., Shieh A., Swarup V., Szekely A., Wang D., Warrell J., Weissman S., Weng Z., White K., Wiseman J., Witt H., Won H., Wood S., Wu F., Xu X., Yao L., Zandi P., Arranz M.J., Bakker S., Bender S., Crepo-Facorro B., Hall J., Iyegbe C., Kahn R., Lawrie S., Lewis C., Lin K., Linszen D.H., Mata I., Walshe M., Weisbrod M., Achsel T., Andres-Alonso M., Bagni C., Bayés À., Biederer T., Brose N., Brown T.C., Chua J.J.E., Coba M.P., Cornelisse L.N., de Jong A.P.H., de Juan-Sanz J., Dieterich D.C., Feng G., Goldschmidt H.L., Gundelfinger E.D., Hoogenraad C., Huganir R.L., Imig C., Jahn R., Jung H., Kaeser P.S., Kim E., Koopmans F., Kreutz M.R., Lipstein N., MacGillavry H.D., Malenka R., McPherson P.S., O’Connor V., Pielot R., Ryan T.A., Sahasrabudhe D., Sala C., Sheng M., Smalla K.-H., Smit A.B., Südhof T.C., Thomas P.D., Toonen R.F., van Weering J.R.T., Verpelli C., Adolfsson R., Arango C., Baune B.T., Belangero S.I., Børglum A.D., Braff D., Bramon E., Buxbaum J.D., Campion D., Cervilla J.A., Cichon S., Collier D.A., Corvin A., Curtis D., Forti M.D., Domenici E., Ehrenreich H., Escott-Price V., Esko T., Fanous A.H., Gawlik M., Gejman P.V., Gill M., Glatt S.J., Golimbet V., Hong K.S., Hultman C.M., Hyman S.E., Iwata N., Jönsson E.G., Kahn R.S., Kennedy J.L., Khusnutdinova E., Kirov G., Knowles J.A., Krebs M.-O., Laurent-Levinson C., Lee J., Lencz T., Levinson D.F., Li Q.S., Liu J., Malhotra A.K., Malhotra D., McIntosh A., McQuillin A., Menezes P.R., Morgan V.A., Morris D.W., Mowry B.J., Murray R.M., Nimgaonkar V., Nöthen M.M., Ophoff R.A., Paciga S.A., Palotie A., Pato C.N., Qin S., Rietschel M., Riley B.P., Rivera M., Rujescu D., Saka M.C., Sanders A.R., Schwab S.G., Serretti A., Sham P.C., Stefánsson H., Stefansson K., Tsuang M.T., Vawter M.P., Weinberger D.R., Werge T., Wildenauer D.B., Yu X., Yue W., Holmans P.A., Pocklington A.J., Roussos P., Vassos E., Verhage M., Visscher P.M., Yang J., Posthuma D., Andreassen O.A., Kendler K.S., Owen M.J., Wray N.R., Daly M.J., Huang H., Neale B.M., Sullivan P.F., Ripke S., Walters J.T.R., O’Donovan M.C., de Haan L., van Amelsvoort T., van Winkel R., Gareeva A., Shi Y., St Clair D., van Os J., PsychENCODE. Mapping genomic loci implicates genes and synaptic biology in schizophrenia. NATURE. 2022; 604(7906)DOI:10.1038/s41586-022-04434-5. PMID:35396580. IF:64.800(Q1/1D).
08/04/2022
Endogenous Syngap1 alpha splice forms promote cognitive function and seizure protection
Kilinc M., Arora V., Creson T.K., Rojas C., Le A.A., Lauterborn J., Wilkinson B., Hartel N., Graham N., Reich A., Gou G., Araki Y., Bayés À., Coba M., Lynch G., Miller C.A., Rumbaugh G.. Endogenous Syngap1 alpha splice forms promote cognitive function and seizure protection. eLife. 2022; 11DOI:10.7554/eLife.75707. PMID:35394425. IF:7.700(Q1/1D).
15/10/2021
21st century excitatory amino acid research: A Q & A with Jeff Watkins and Dick Evans
Watkins, JC, Evans, RH, Bayes, A, Booker, SA, Gibb, A, Mabb, AM, Mayer, M, Mellor, JR, Molnar, E, Niu, L, Ortega, A, Pankratov, Y, Ramos-Vicente, D, Rodriguez-Campuzano, A, Rodriguez-Moreno, A, Wang, LY, Wang, YT, Wollmuth, L, Wyllie, DJA, Zhuo, M, Frenguelli, BG. 21st century excitatory amino acid research: A Q & A with Jeff Watkins and Dick Evans. NEUROPHARMACOLOGY. 2021; 198DOI:10.1016/j.neuropharm.2021.108743. PMID:34363811. IF:5.273(Q1/3D).
01/09/2021
Metazoan evolution and diversity of glutamate receptors and their auxiliary subunits
Ramos-Vicente, D, Grant, SGN, Bayes, A. Metazoan evolution and diversity of glutamate receptors and their auxiliary subunits. NEUROPHARMACOLOGY. 2021; 195DOI:10.1016/j.neuropharm.2021.108640. PMID:34116111. IF:5.273(Q1/3D).
01/08/2021
epsilon-Sarcoglycan: Unraveling the Myoclonus-Dystonia Gene
Cazurro-Gutierrez, A, Marce-Grau, A, Correa-Vela, M, Salazar, A, Vanegas, MI, Macaya, A, Bayes, A, Perez-Duenas, B. epsilon-Sarcoglycan: Unraveling the Myoclonus-Dystonia Gene. MOLECULAR NEUROBIOLOGY. 2021; 58(8)DOI:10.1007/s12035-021-02391-0. PMID:33886091. IF:5.686(Q2/3D).
02/12/2025
Vascular Endothelial Growth Factor-A and Collateral Circulation in Patients with Acute Ischemic Stroke due to Intracranial Large Vessel Occlusion
Aguilera-Simon, A, Guasch-Jiménez, M, Moniche, F, Puig, N, Pardo-Galiana, B, Benítez, S, Freijo, MD, Marín, R, Luna, A, Gallego-Fabrega, C, Fernández-Pérez, I, Ezcurra-Díaz, G, Jiménez-Conde, J, Lambea-Gil, A, Gomez-Vicente, B, Martínez-Domeño, A, Arenillas, JF, Prats-Sánchez, L, Rodríguez-Pardo, J, Ramos-Pachon, A, de Celis-Ruiz, E, Martínez-González, JP, Trillo, S, Ortega-Quintanilla, J, Martí-Fàbregas, J, Camps-Renom, P. Vascular Endothelial Growth Factor-A and Collateral Circulation in Patients with Acute Ischemic Stroke due to Intracranial Large Vessel Occlusion. Translational Stroke Research. 2025; 17(1)DOI:10.1007/s12975-025-01399-1. PMID:41326757. IF:4.300(Q1/2D).
01/11/2025
Influence of dehydration on collateral circulation and clinical outcome after endovascular therapy in patients with acute ischemic stroke
Guasch-Jiménez, M, Camps-Renom, P, Toscano-Prat, C, Guisado-Alonso, D, Martinez-Domeño, A, Prats-Sánchez, L, Ramos-Pachon, A, Fernández-Cadenas, I, Martínez-González, JP, Fernández-Pérez, I, Avellaneda-Gomez, C, de Celis-Ruiz, E, Rodríguez-Pardo, J, Freijo, MD, Luna, A, Moniche, F, Pardo-Galiana, B, Ortega-Quintanilla, J, Arenillas, JF, Cortijo, E, Martí-Fàbregas, J. Influence of dehydration on collateral circulation and clinical outcome after endovascular therapy in patients with acute ischemic stroke. NEUROLOGIA. 2025; 40(9)DOI:10.1016/j.nrl.2023.04.007. PMID:41077187. IF:3.100(Q2/4D).
28/10/2025
Plasma proteomics uncovers divergent molecular signatures in ischemic stroke and intracerebral hemorrhage
Núñez-Jurado, D, Fernández-Vega, A, del Río, C, Penalba, A, Llucià-Carol, L, Muiño-Acuña, E, Ezcurra-Díaz, G, Guasch-Jiménez, M, Cullell, N, Serrano-Heras, G, Arias-Salazar, L, Vives-Bauza, C, Tur, S, Urra, X, Castellanos, M, Krupinski, J, Freijo-Guerrero, M, Jiménez-Conde, J, Fernández-Pérez, I, Segura, T, Marti-Fabregas, J, Férnandez-Cadenas, I, Montaner, J. Plasma proteomics uncovers divergent molecular signatures in ischemic stroke and intracerebral hemorrhage. Biomarker Research. 2025; 13(1)DOI:10.1186/s40364-025-00848-1. PMID:41152969. IF:11.500(Q1/1D).
10/10/2025
VEGFA sex-specific signature is associated to long COVID symptom persistence
Farré, X, Blay, N, Iraola-Guzmán, S, Fernández-Jiménez, F, Alzate-Piñol, S, Llucià-Carol, L, Espinosa, A, Castaño-Vinyals, G, Dobaño, C, Moncunill, G, Karachaliou, M, Garcia-Aymerich, J, Kogevinas, M, Barceló, C, Cadenas, I, de Cid, R. VEGFA sex-specific signature is associated to long COVID symptom persistence. BMC Medicine. 2025; 23(1)DOI:10.1186/s12916-025-04402-6. PMID:41074076. IF:8.300(Q1/1D).
01/10/2025
Blood Biospecimen Recommendations for Research on Stroke Outcomes and Recovery
Braun, RG, Edwardson, MA, Aldridge, CM, Cramer, SC, Cruchaga, C, Engelter, ST, Lee, JM, Maguire, JM, Stanne, TM, Stamova, B, Traenka, C, Gallego-Fabrega, C, Cadenas, IF, Lindgren, AG. Blood Biospecimen Recommendations for Research on Stroke Outcomes and Recovery. STROKE. 2025; 56(10)DOI:10.1161/STROKEAHA.125.050793. PMID:40982604. IF:8.900(Q1/1D).
01/09/2025
Rare Variant Association Analysis Uncovers Involvement of VNN2 in Stroke Outcome
Alcaide-Consuegra, E, Mola-Caminal, M, Escaramís, G, Lazcano, U, Fernández-Pérez, I, Reig-Palou, J, Jiménez-Balado, J, Giralt-Steinhauer, E, Cuadrado-Godia, E, Ois, A, Rodríguez-Campello, A, Vallverdú-Prats, M, Medina-Dols, A, Jiménez, C, Tur, S, Díaz-Navarro, RM, Bruque, CD, Andreu-Somavilla, N, González-Navarrete, I, Casals, F, Vives-Bauzà, C, Fernández-Cadenas, I, Jiménez-Conde, J, Balcells, S, Rabionet, R. Rare Variant Association Analysis Uncovers Involvement of VNN2 in Stroke Outcome. STROKE. 2025; 56(9)DOI:10.1161/STROKEAHA.124.049365. PMID:40495801. IF:8.900(Q1/1D).
01/07/2025
Influence of the Gut Microbiota on Acute Ischemic Stroke Functional Outcomes at Three Months
Lledós, M, Prats-Sánchez, L, Muiño, E, Cullell, N, Llucià-Carol, L, Cárcel-Márquez, J, Gallego-Fabrega, C, Martín-Campos, JM, Marín, R, Aguilera-Simón, A, Guasch-Jiménez, M, Ezcurra-Díaz, G, Camps-Renom, P, Freijo, MD, Martí-Fàbregas, J, Fernández-Cadenas, I. Influence of the Gut Microbiota on Acute Ischemic Stroke Functional Outcomes at Three Months. EUROPEAN JOURNAL OF NEUROLOGY. 2025; 32(7)DOI:10.1111/ene.70265. PMID:40686474. IF:3.900(Q1/3D).
13/05/2025
Influence of Asymptomatic Hemorrhagic Transformation After Endovascular Treatment on Stroke Outcome
Guasch-Jiménez, M, Díaz, GE, Lambea-Gil, A, Ramos-Pachón, A, Martinez-Domeño, A, Prats-Sanchez, L, Fernández-Vidal, JM, Toscano-Prat, C, Marti-Fabregas, J, Martínez-González, JP, Fernandez-Cadenas, I, Cardona, P, Rodriguez-Villatoro, N, Vázquez, AR, Gomis, M, Xuclà-Ferrarons, T, Rodriguez-Campello, A, Cánovas, D, Seró, L, Purroy, F, Salvat-Plana, M, Abilleira, S, Camps-Renom, P. Influence of Asymptomatic Hemorrhagic Transformation After Endovascular Treatment on Stroke Outcome. NEUROLOGY. 2025; 104(9)DOI:10.1212/WNL.0000000000213509. PMID:40228188. IF:8.500(Q1/1D).
01/04/2025
Early automated cerebral edema assessment following endovascular therapy: impact on stroke outcome
Guasch-Jiménez, M, Dhar, R, Kumar, A, Cifarelli, J, Ezcurra-Díaz, G, Lambea-Gil, A, Ramos-Pachón, A, Martínez-Domeño, A, Prats-Sánchez, L, Guisado-Alonso, D, Fernández-Cadenas, I, Aguilera-Simón, A, Marín, R, Martínez-González, J, Ortega-Quintanilla, J, Fernández-Pérez,I, Avellaneda-Gómez, C, Rodríguez-Pardo, J, de Celis, E, Moniche, F, Freijo, M, Cortijo, E, Trillo, S, Camps-Renom, P, Martí-Fábregas , J. Early automated cerebral edema assessment following endovascular therapy: impact on stroke outcome. Journal of NeuroInterventional Surgery. 2025; 17(4)DOI:10.1136/jnis-2024-021641. PMID:38637151. IF:4.300(Q1/1D).
27/02/2025
NOTCH3 Variant Position Affects the Phenotype at the Pluripotent Stem Cell Level in CADASIL
Bugallo-Casal, A, Muiño, E, Bravo, SB, Hervella, P, Arias-Rivas, S, Rodríguez-Yáñez, M, Vara-León, E, Quintas-Rey, R, Perez-Gayol, L, Maisterra-Santos, O, Pizarro-Gonzálvez, J, Martorell-Riera, MR, Vives-Bauzá, C, Fernández-Cadenas, I, Castillo, J, Campos, F. NOTCH3 Variant Position Affects the Phenotype at the Pluripotent Stem Cell Level in CADASIL. NEUROMOLECULAR MEDICINE. 2025; 27(1)DOI:10.1007/s12017-025-08840-6. PMID:40016442. IF:3.900(Q2/3D).
13/02/2025
Plasma Hepcidin as a potential informative biomarker of Alzheimer disease and vascular dementia
Delaby, C, Alcolea, D, Busto, G, Gabelle, A, Ayrignac, X, Bennys, K, Muiño, E, Villatoro, P, Fernández-Cadenas, I, Pradeilles, N, El Bounasri, S, Torres, S, Hirtz, C, Zetterberg, H, Lleó, A, Fortea, J, Lehmann, S. Plasma Hepcidin as a potential informative biomarker of Alzheimer disease and vascular dementia. Alzheimers Research & Therapy. 2025; 17(1)DOI:10.1186/s13195-025-01696-9. PMID:39948603. IF:7.600(Q1/1D).
01/01/2025
Disease Severity Staging System for NOTCH3-Associated Small Vessel Disease, Including CADASIL
Gravesteijn, G, Rutten, JW, Cerfontaine, MN, Hack, RJ, Liao, YC, Jolly, AA, Guey, S, Hsu, SL, Park, JY, Yuan, Y, Kopczak, A, Rifino, N, Neilson, SJ, Poggesi, A, Shourav, MMI, Saito, S, Ishiyama, H, Mayoral, AD, Nogueira, R, Muino, E, Andersen, P, De Stefano, N, Santo, G, Sukhonpanich, N, Mele, F, Park, A, Lee, JS, Rodriguez-Girondo, M, Vonk, SJJ, Brodtmann, A, Boerjesson-Hanson, A, Pantoni, L, Fernandez-Cadenas, I, Silva, AR, Montanaro, VVA, Kalaria, RN, Lopergolo, D, Ihara, M, Meschia, JF, Muir, KW, Bersano, A, Pescini, F, Duering, M, Choi, JC, Ling, C, Kim, H, Markus, HS, Chabriat, H, Lee, YC, Oberstein, SAJL. Disease Severity Staging System for NOTCH3-Associated Small Vessel Disease, Including CADASIL. JAMA Neurology. 2025; 82(1)DOI:10.1001/jamaneurol.2024.4487. PMID:39610302. IF:21.300(Q1/1D).
01/10/2024
Sex-Stratified Genome-Wide Association Study in the Spanish Population Identifies a Novel Locus for Lacunar Stroke
Cárcel-Márquez, J, Muiño, E, Gallego-Fabrega, C, Cullell, N, Lledós, M, Llucià-Carol, L, Martín-Campos, JM, Sobrino, T, Campos, F, Castillo, J, Freijo, M, Arenillas, JF, Obach, V, Alvarez-Sabín, J, Molina, CA, Ribó, M, Jiménez-Conde, J, Roquer, J, Muñoz-Narbona, L, Lopez-Cancio, E, Millán, M, Diaz-Navarro, R, Vives-Bauza, C, Serrano-Heras, G, Segura, T, Ibañez, L, Heitsch, L, Delgado, P, Dhar, R, Krupinski, J, Prats-Sánchez, L, Camps-Renom, P, Guasch, M, Ezcurra, G, Blay, N, Sumoy, L, de Cid, R, Montaner, J, Cruchaga, C, Lee, JM, Martí-Fàbregas, J, Férnandez-Cadenas, I. Sex-Stratified Genome-Wide Association Study in the Spanish Population Identifies a Novel Locus for Lacunar Stroke. STROKE. 2024; 55(10)DOI:10.1161/STROKEAHA.124.047833. PMID:39315829. IF:8.900(Q1/1D).
19/06/2024
Crossed-reflex in antiphospholipid chorea
Fernández-Vidal, JM, Olmedo-Saura, G, Querol-Gutiérrez, LA, Kulisevsky, J, Pérez-Pérez, J. Crossed-reflex in antiphospholipid chorea. NEUROLOGICAL SCIENCES. 2024; 45(9)DOI:10.1007/s10072-024-07622-5. PMID:38896185. IF:2.400(Q3/6D).
06/06/2024
DNA methylation and stroke prognosis: an epigenome-wide association study
Jiménez-Balado, J, Fernández-Pérez, I, Gallego-Fábrega, C, Lazcano, U, Soriano-Tárraga, C, Vallverdú-Prats, M, Mola-Caminal, M, Rey-Alvarez, L, Macias-Gómez, A, Suárez-Pérez, A, Giralt-Steinhauer, E, Rodríguez-Campello, A, Cuadrado-Godia, E, Ois, A, Esteller, M, Roquer, J, Fernández-Cadenas, I, Jiménez-Conde, J. DNA methylation and stroke prognosis: an epigenome-wide association study. Clinical Epigenetics. 2024; 16(1)DOI:10.1186/s13148-024-01690-2. PMID:38845005. IF:4.400(Q1/2D).
01/06/2024
External validation of a bleeding risk assessment model developed with natural language processing and machine learning (PREDICT-AI study) in patients with anticoagulated cancer with venous thromboembolism in the TESEO international prospective registry
Martin, AJM, Beneitez, MCV, Perez, CI, Sanchez-Canovas, M, Rubio, J, Martinez, MP, de Herreros, MG, De Castro, EM, Fernandez, I, Escobar, IG, Porta, R, Brozos, E, Quintanar, MT, Adrian, SG, Sanchez, SG, Covela, M, Crespo, JS, Pelegrin, F, Carmona-Bayonas, A, Jimenez-Fonseca, P. External validation of a bleeding risk assessment model developed with natural language processing and machine learning (PREDICT-AI study) in patients with anticoagulated cancer with venous thromboembolism in the TESEO international prospective registry. JOURNAL OF CLINICAL ONCOLOGY. 2024; 42(16)DOI:. PMID:. IF:41.900(Q1/1D).
01/04/2024
A multitrait genetic study of hemostatic factors and hemorrhagic transformation after stroke treatment
Gallego-Fabrega C., Temprano-Sagrera G., Cárcel-Márquez J., Muiño E., Cullell N., Lledós M., Llucià-Carol L., Martin-Campos J.M., Sobrino T., Castillo J., Millán M., Muñoz-Narbona L., López-Cancio E., Ribó M., Alvarez-Sabin J., Jiménez-Conde J., Roquer J., Tur S., Obach V., Arenillas J.F., Segura T., Serrano-Heras G., Marti-Fabregas J., Freijo-Guerrero M., Moniche F., Castellanos M.D.M., Morrison A.C., Smith N.L., de Vries P.S., Fernández-Cadenas I., Sabater-Lleal M., Dehghan A., Heath A.S., Reiner A.P., Johnson A., Richmond A., Peters A., van Hylckama Vlieg A., McKnight B., Psaty B.M., Hayward C., Ward-Caviness C., O'Donnell C., Chasman D., Strachan D.P., Tregouet D.A., Mook-Kanamori D., Gill D., Thibord F., Asselbergs F.W., Leebeek F.W.G., Rosendaal F.R., Davies G., Homuth G., Temprano G., Campbell H., Taylor H.A., Bressler J., Huffman J.E., Rotter J.I., Yao J., Wilson J.F., Bis J.C., Hahn J.M., Desch K.C., Wiggins K.L., Díez-Ahijado L., Raffield L.M., Bielak L.F., Yanek L.R., Kleber M.E., Mueller M., Kavousi M., Mangino M., Conomos M.P., Liu M., Brown M.R., Jhun M.-A., Chen M.-H., de Maat M.P.M., Pankratz N., Peyser P.A., Elliot P., Wei P., Wild P.S., Morange P.E., van der Harst P., Yang Q., Marioni R., Li R., Damrauer S.M., Cox S.R., Trompet S., Felix S.B., Völker U., Tang W., Koenig W., Jukema J.W., Guo X.. A multitrait genetic study of hemostatic factors and hemorrhagic transformation after stroke treatment. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2024; 22(4)DOI:10.1016/j.jtha.2023.11.027. PMID:38103737. IF:5.000(Q1/2D).