Search
14/06/2025
Efficacy and safety of first-line maintenance therapy with lurbinectedin plus atezolizumab in extensive-stage small-cell lung cancer (IMforte): a randomised, multicentre, open-label, phase 3 trial
Paz-Ares, L, Borghaei, H, Liu, S, Peters, S, Herbst, RS, Stencel, K, Majem, M, Sendur, MAN, Czyzewicz, G, Caro, RB, Lee, KH, Johnson, ML, Karadurmus, N, Grohé, C, Baka, S, Csoszi, T, Ahn, JS, Califano, R, Yang, TY, Kemal, Y, Ballinger, M, Cuchelkar, V, Graupner, V, Lin, YC, Chakrabarti, D, Bhatt, K, Cai, G, Iannone, R, Reck, M. Efficacy and safety of first-line maintenance therapy with lurbinectedin plus atezolizumab in extensive-stage small-cell lung cancer (IMforte): a randomised, multicentre, open-label, phase 3 trial. LANCET. 2025; 405(10495)DOI:10.1016/S0140-6736(25)01011-6. PMID:40473449. IF:88.500(Q1/1D).
01/06/2025
Induction of neoantigen-specific immune responses by VB10.NEO in combination with atezolizumab in heavily pretreated patients with advanced solid tumors: Final analysis of the phase 1b VB N-02 trial.
Ochsenreither, S, Anguera, G, Dieter, S, Trikalinos, N, Fu, SQ, Fernández, BC, Ferrandiz, AC, Kim, SY, Rodriguez, LM, Berg, KCG, Hassan, HIB, Rosholm, A, Fredriksen, AB. Induction of neoantigen-specific immune responses by VB10.NEO in combination with atezolizumab in heavily pretreated patients with advanced solid tumors: Final analysis of the phase 1b VB N-02 trial.. JOURNAL OF CLINICAL ONCOLOGY. 2025; 43(16_SUPPL)DOI:10.1200/JCO.2025.43.16_suppl.2639. PMID:. IF:41.900(Q1/1D).
01/06/2025
Molecular residual disease analysis of adjuvant osimertinib in resected EGFR-mutated stage IB-IIIA non-small-cell lung cancer
Herbst, RS, John, T, Grohé, C, Goldman, JW, Kato, T, Laktionov, K, Bonanno, L, Tiseo, M, Majem, M, Dómine, M, Ahn, MJ, Kowalski, DM, Pérol, M, Sriuranpong, V, Özgüroglu, M, Bhetariya, P, Markovets, A, Rukazenkov, Y, Muldoon, C, Robichaux, J, Hartmaier, R, Tsuboi, M, Wu, YL. Molecular residual disease analysis of adjuvant osimertinib in resected EGFR-mutated stage IB-IIIA non-small-cell lung cancer. NATURE MEDICINE. 2025; 31(6)DOI:10.1038/s41591-025-03577-y. PMID:40097663. IF:50.000(Q1/1D).
01/06/2025
Predictors of withdrawal of anticancer drug indications granted accelerated approval: a retrospective cohort study
Tibau, A, Cliff, ERS, Romano, A, Borrell, M, Molto, C, Kesselheim, AS. Predictors of withdrawal of anticancer drug indications granted accelerated approval: a retrospective cohort study. Eclinicalmedicine. 2025; 84DOI:10.1016/j.eclinm.2025.103088. PMID:40687736. IF:10.000(Q1/1D).
13/05/2025
Pilot Investigation on Markers of Bone Metabolism, Angiogenesis, and Neuroendocrine Activity as Potential Predictors of Survival of Metastatic Prostate Cancer Patients with Bone Metastases
Ortiz, MA, Anguera, G, Cantó, E, Alejandre, J, Mora, J, Osuna-Gómez, R, Mulet, M, Mora, P, Antonijuan, A, Sánchez, S, Ramírez, O, Orantes, V, Maroto, P, Vidal, S. Pilot Investigation on Markers of Bone Metabolism, Angiogenesis, and Neuroendocrine Activity as Potential Predictors of Survival of Metastatic Prostate Cancer Patients with Bone Metastases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2025; 26(10)DOI:10.3390/ijms26104669. PMID:40429810. IF:4.900(Q1/3D).
01/05/2025
Primary Results from IMscin002: A Study to Evaluate Patient Preferences and Perceptions of Health Care Professionals for Atezolizumab Subcutaneous Versus Intravenous for the Treatment of NSCLC
Cappuzzo, F, Zvirbule, Z, Korbenfeld, E, Kolb-Sielecki, J, Isla, D, Szczesna, A, Sanchez, AYC, Bustillos, A, Liu, XY, Young, F, Tosti, N, Monteiro, MF, Majem, M. Primary Results from IMscin002: A Study to Evaluate Patient Preferences and Perceptions of Health Care Professionals for Atezolizumab Subcutaneous Versus Intravenous for the Treatment of NSCLC. Jto Clinical And Research Reports. 2025; 6(5)DOI:10.1016/j.jtocrr.2025.100815. PMID:40248457. IF:(Q/D).
18/04/2025
The Effect of Staging Intervals on Progression-Free Survival in Registration Studies of Oncologic Drugs: A Meta-Analysis
Zuellig, JA, Adam, R, Udry, F, Tibau, A, Seruga, B, Ocana, A, Amir, E, Templeton, AJ. The Effect of Staging Intervals on Progression-Free Survival in Registration Studies of Oncologic Drugs: A Meta-Analysis. Cancers. 2025; 17(8)DOI:10.3390/cancers17081359. PMID:40282533. IF:4.400(Q2/3D).
01/04/2025
Will I feel better? Raising the bar for quality of life in oncology
Tibau, A, Romano, A, Kesselheim, AS. Will I feel better? Raising the bar for quality of life in oncology. Nature Reviews Clinical Oncology. 2025; 22(4)DOI:10.1038/s41571-025-01002-4. PMID:40021787. IF:82.200(Q1/1D).
01/04/2025
Retifanlimab in Advanced Penile Squamous Cell Carcinoma: The Phase 2 ORPHEUS Study
Del Muro, XG, López-Bravo, DP, Cuéllar-Rivas, MA, Maroto, P, Giannatempo, P, Castellano, D, Climent, MA, Valderrama, BP, de Liaño, AG, López-Montero, L, Mina, L, Alcalá-López, D, Sampayo-Cordero, M, Necchi, A. Retifanlimab in Advanced Penile Squamous Cell Carcinoma: The Phase 2 ORPHEUS Study. European Urology Oncology. 2025; 8(2)DOI:10.1016/j.euo.2024.04.021. PMID:38749903. IF:9.300(Q1/1D).
01/04/2025
A randomised non-comparative phase II study of atezolizumab, bevacizumab and chemotherapy in EGFR-mutant NSCLC with acquired resistance - The ETOP 15-19 ABC-lung trial
Soo, RA, Vervita, K, Früh, M, Cho, B, Majem, M, Abreu, DR, Ribi, K, Callejo, A, Moran, T, Gomez, MD, Provencio, M, Addeo, A, Han, JY, Granados, ALO, Reck, M, Blasco, A, Campelo, RG, González, MAS, Britschgi, C, Roschitzki-Voser, H, Ruepp, B, Gasca-Ruchti, A, Haberecker, M, Dafni, U, Peters, S, Stahel, RA. A randomised non-comparative phase II study of atezolizumab, bevacizumab and chemotherapy in EGFR-mutant NSCLC with acquired resistance - The ETOP 15-19 ABC-lung trial. LUNG CANCER. 2025; 202DOI:10.1016/j.lungcan.2025.108454. PMID:40023017. IF:4.400(Q1/2D).
28/03/2025
Beyond the status quo: when disease volume and metastatic timing are not enough to personalize treatment in mHSPC
Borque-Fernando, A, Alonso-Gordoa, T, Juan-Fita, MJ, Campos, FL, Pérez-Fentes, DA, Vilaseca, A, Agut, CM, Usán, P, Rey, PM. Beyond the status quo: when disease volume and metastatic timing are not enough to personalize treatment in mHSPC. Future Oncology. 2025; 21(8)DOI:10.1080/14796694.2025.2468569. PMID:40029138. IF:2.600(Q3/6D).
01/03/2025
Baseline PD-L1 expression in circulating neutrophils predicts immune-related adverse events (irAEs) in patients with extensive-stage small-cell lung cancer from CANTABRICO trial
Piedra, A, Guinart-Cuadra, A, Recio, SM, Mulet, M, Atenza, CZ, Alejandre, J, Beltran, JS, Joaquín, AB, Sullivan, IG, López, JS, Casado, MDI, Aperribay, EA, Paz-Ares, L, Tain, PD, Vega, ALM, Callejo, A, Martos, JLL, Dominguez, M, Vidal, S, Majem, M. Baseline PD-L1 expression in circulating neutrophils predicts immune-related adverse events (irAEs) in patients with extensive-stage small-cell lung cancer from CANTABRICO trial. Journal of Thoracic Oncology. 2025; 20(3)DOI:. PMID:. IF:20.800(Q1/1D).
01/03/2025
TACTI-004: A double-blinded, randomized phase III trial in patients with advanced/metastatic non-small cell lung cancer receiving eftilagimod alfa (MHC class II agonist) in combination with pembrolizumab (P) and chemotherapy (C) versus placebo plus P plus C
Majem, M, O'Byrne, KJ, Lo Russo, G, Mueller, C, Triebel, F. TACTI-004: A double-blinded, randomized phase III trial in patients with advanced/metastatic non-small cell lung cancer receiving eftilagimod alfa (MHC class II agonist) in combination with pembrolizumab (P) and chemotherapy (C) versus placebo plus P plus C. Journal of Thoracic Oncology. 2025; 20(3)DOI:. PMID:. IF:20.800(Q1/1D).
01/03/2025
Decrease in Fracture Rate with Mandatory Bone-protecting Agents in the EORTC 1333/PEACE-3 Trial Comparing Radium-223 Combined with Enzalutamide Versus Enzalutamide Alone: A Safety Analysis
Gillessen, S, Tombal, B, Turco, F, Choudhury, A, Rodriguez-Vida, A, Gallardo, E, Velho, PI, Nolè, F, Cruz, F, Loriot, Y, McDermott, R, Roumeguere, T, Daugaard, G, Yamamura, R, Bompas, E, Maroto, P, Polo, MH, da Trindade, KM, Preto, DD, Skoneczna, I, Lecouvet, F, Coens, C, Fournier, B, Saad, F. Decrease in Fracture Rate with Mandatory Bone-protecting Agents in the EORTC 1333/PEACE-3 Trial Comparing Radium-223 Combined with Enzalutamide Versus Enzalutamide Alone: A Safety Analysis. EUROPEAN UROLOGY. 2025; 87(3)DOI:10.1016/j.eururo.2024.11.027. PMID:39827019. IF:25.200(Q1/1D).
01/03/2025
Patient-reported outcomes from CANTABRICO: Durvalumab plus platinum-etoposide in first-line treatment of extensive stage small cell lung cancer
Casado, MDI, Aperribay, EA, Campelo, MRG, Blanco, MCM, Tain, PD, Piqueras, MMLB, Vega, ALM, Mateos, LAL, Rodriguez, JMO, Calderon, VG, Majem, M, Hernandez, AS, de la Rosa, CA, Cabellos, RA, Sureda, BM, Baret, M, Martos, JLL, Dominguez, M, Paz-Ares, L. Patient-reported outcomes from CANTABRICO: Durvalumab plus platinum-etoposide in first-line treatment of extensive stage small cell lung cancer. Journal of Thoracic Oncology. 2025; 20(3)DOI:. PMID:. IF:20.800(Q1/1D).
01/03/2025
First-line (1L) fulzerasib plus cetuximab in KRAS G12Cm advanced NSCLC: Updated efficacy and safety from KROCUS study
Majem, M, Gregorc, V, Lo Russo, G, Maio, M, Salvagni, S, Calderon, VG, Cao, MG, Contreras, SS, Koumarianou, A, Bearz, A, Caro, RB, Viteri, S, Sanmamed, MF, Zagouri, F, Bueno, MTM, Zhang, Y, Shan, Y, Zhu, H, Rosell, R. First-line (1L) fulzerasib plus cetuximab in KRAS G12Cm advanced NSCLC: Updated efficacy and safety from KROCUS study. Journal of Thoracic Oncology. 2025; 20(3)DOI:. PMID:. IF:20.800(Q1/1D).
01/03/2025
Long-term survivors with extensive-stage small-cell lung cancer treated with first-line durvalumab plus carboplatin and etoposide: The CANTABRICO trial
Casado, MDI, Aperribay, EA, Campelo, MRG, Blanco, CM, Tain, PD, Piqueras, MMLB, Vega, ALM, Mateos, LAL, Rodriguez, JMO, Calderon, VG, Majem, M, Hernandez, AS, de la Rosa, CA, Cabellos, RA, Sureda, BM, Baret, M, Martos, JLL, Dominguez, M, Paz-Ares, L. Long-term survivors with extensive-stage small-cell lung cancer treated with first-line durvalumab plus carboplatin and etoposide: The CANTABRICO trial. Journal of Thoracic Oncology. 2025; 20(3)DOI:. PMID:. IF:20.800(Q1/1D).
01/03/2025
Analysis of tumor budding as a prognostic factor for recurrence in patients with stage II and III colon cancer. Experience in a tertiary hospital
Rueda-Lara, A, Viñal, D, Martínez-Pérez, D, Alameda-Guijarro, M, Martin-Montalvo, G, Martínez-Recio, S, Peña-Lopez, J, Jiménez-Bou, D, Ruíz-Gutiérrez, I, García-Leal, A, Zwisler-Contreras, P, Ghanem, I, Custodio, AB, Pérez-Wert, P, Gutiérrez-Sainz, L, Palacios, ME, Feliu, J, Rodríguez-Salas, N. Analysis of tumor budding as a prognostic factor for recurrence in patients with stage II and III colon cancer. Experience in a tertiary hospital. ONCOLOGIST. 2025; 30(3)DOI:10.1093/oncolo/oyaf027. PMID:40152315. IF:4.200(Q2/3D).
10/02/2025
Impact of site of metastatic involvement on IMDC classification in metastatic renal cell carcinoma patients treated with immunotherapy.
Fernandez-Mañas, L, Ortiz, I, Pozas, J, Beland, C, Larkin, J, Moll-Febrer, A, González-Aguado, L, Beltran, JS, Anguera, G, Navarro, N, Rodriguez-Vida, A, Novella, SR, Sierra, M, Carrasco, A, González, NS, Yonamine, EPM, Maeso, IG, Figols, M, Alcalá, MM, Reig, O. Impact of site of metastatic involvement on IMDC classification in metastatic renal cell carcinoma patients treated with immunotherapy.. JOURNAL OF CLINICAL ONCOLOGY. 2025; 43(5_SUPPL)DOI:10.1200/JCO.2025.43.5_suppl.483. PMID:. IF:41.900(Q1/1D).
10/02/2025
Impact of deferred cytoreductive nephrectomy in the era of the immunotherapy in metastatic renal cell carcinoma: A multicenter retrospective study.
Rioja, P, Passarella, C, Angel, M, Valderrama, W, Bosma, F, Anguera, G, Gomez, V, Ruiz-Granados, A, Plata, D, Laguado, MIZ, Orta-Ruiz, A, Gandur-Quiroga, MN, Bourlon, MT, Grande, E, Manneh, R, Molina-Cerrillo, J, Maroto-Rey, P, Sade, JP, Castellano, D. Impact of deferred cytoreductive nephrectomy in the era of the immunotherapy in metastatic renal cell carcinoma: A multicenter retrospective study.. JOURNAL OF CLINICAL ONCOLOGY. 2025; 43(5_SUPPL)DOI:10.1200/JCO.2025.43.5_suppl.502. PMID:. IF:41.900(Q1/1D).