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01/11/2025
Novel approaches for the discovery of pharmacogenetic biomarkers of chemotoxicity in patients with colorectal cancer
Simoes, AR, González, SC, Lopez-Doldan, MD, Duran, G, Fernández-Montes, A, Fernandez, MP, Fernandez, MS, Mata, JG, Paez, D, Riera, P, Guino, E, Lopez-Fernandez, L, de Santiago, BG, Aspiroz, EL, Rojas, A, Castells, A, Castellvi-Bel, S, Ponte, CR, Vymetalkova, V, Carracedo, A, Fernandez-Rozadilla, C. Novel approaches for the discovery of pharmacogenetic biomarkers of chemotoxicity in patients with colorectal cancer. BRITISH JOURNAL OF PHARMACOLOGY. 2025; 182(21)DOI:10.1111/bph.70051. PMID:40624839. IF:7.700(Q1/1D).
01/11/2025
Durvalumab plus platinum-etoposide in the first-line treatment of extensive-stage small cell lung cancer (CANTABRICO): A single-arm clinical trial
Isla, D, Zugazagoitia, J, Arriola, E, García-Campelo, R, Blanco, CM, Diz-Taín, MP, Lopez-Brea, M, Moreno-Vega, AL, León-Mateos, L, Oramás, J, Gutiérrez-Calderón, V, Majem, M, Sánchez-Hernández, A, Aguado, C, Alvarez-Cabellos, R, Massutí, B, Moreno, A, Fírvida-Pérez, JL, Valdivia, J, González-Cordero, M, Zafra-Poves, M, Dómine, M, Garcia-Navalon, FJ, Villanueva, N, Provencio, M, Juan-Vidal, O, Rivas-Corredor, C, García, MEO, Palmero, R, López-Castro, R, Carcereny, E, Lechuga, JL, Domínguez, M, Callejo, A, Paz-Ares, L. Durvalumab plus platinum-etoposide in the first-line treatment of extensive-stage small cell lung cancer (CANTABRICO): A single-arm clinical trial. LUNG CANCER. 2025; 209DOI:10.1016/j.lungcan.2025.108763. PMID:41033130. IF:4.400(Q1/2D).
01/11/2025
Predictive factors of efficacy for FTD/TPI plus bevacizumab in refractory metastatic colorectal cancer patients: a subanalysis of the Spanish cohort from the SUNLIGHT phase III trial
Soler, G, Grávalos, C, Rivera, F, Safont, MJ, Virgili, AC, Valladares-Ayerbes, M, Ferreiro-Monteagudo, R, Ortiz-Morales, MJ, Polo-Marques, E, Kornusova-Bersheva, I, Soustre, E, Yao, WY, Élez, E. Predictive factors of efficacy for FTD/TPI plus bevacizumab in refractory metastatic colorectal cancer patients: a subanalysis of the Spanish cohort from the SUNLIGHT phase III trial. Clinical & Translational Oncology. 2025; 27(11)DOI:10.1007/s12094-025-03907-z. PMID:40338282. IF:2.500(Q3/6D).
01/11/2025
Long-term outcomes from pembrolizumab monotherapy in patients with advanced NSCLC, PD-L1 expression = 50 %, and poor performance status: Transformer-based AI to characterize prognostic complexity
Cortellini, A, Garbo, E, La Cava, G, Citarella, F, Santo, V, Brunetti, L, Pinato, DJ, Naidoo, J, Loza, M, Genova, C, Gettinger, S, Kim, SY, Jayakrishnan, R, El Zarif, T, Russano, M, Pecci, F, Di Federico, A, Montrone, M, Owen, DH, Signorelli, D, Li, MJ, Camerini, A, Halmos, B, Vincenzi, B, Metro, G, Yendamuri, S, Grossi, F, Josephides, E, Tomasik, B, Giusti, R, Bria, E, Sebastian, M, Rost, M, Acker, F, Landi, L, Mazzoni, F, Morabito, A, Leonetti, A, Cantini, L, Mountzios, G, Kalvapudi, S, O'Reilly, D, Karapanagiotou, E, Monnet, I, Baena, J, Macerelli, M, Majem, M, Piedra, A, Cortinovis, DL, Tonini, G, Minuti, G, Mezquita, L, Gorria, T, Beninato, T, Lo Russo, G, Prelaj, A, De Giglio, A, Biello, F, Nana, FA, Dingemans, AMC, Aerts, JG, Ferrara, R, Abu Hejleh, T, Takada, K, Naqash, AR, Garassino, MC, Wakelee, HA, Nassar, A, Ricciuti, B, Soda, P, Caruso, CM, Guarrasi, V. Long-term outcomes from pembrolizumab monotherapy in patients with advanced NSCLC, PD-L1 expression = 50 %, and poor performance status: Transformer-based AI to characterize prognostic complexity. LUNG CANCER. 2025; 209DOI:10.1016/j.lungcan.2025.108799. PMID:41108882. IF:4.400(Q1/2D).
01/11/2025
Self-disintegrating protein-leaking microparticles for topical protein delivery
Volta-Durán, E, Sánchez, JM, Favaro, MTP, Martinez-Cuentra, G, Contreras, E, di Somma, A, López-Laguna, H, Unzueta, U, Casanova, I, Mangues, R, Villaverde, A, Vázquez, E. Self-disintegrating protein-leaking microparticles for topical protein delivery. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2025; 329DOI:10.1016/j.ijbiomac.2025.147730. PMID:40967544. IF:8.500(Q1/1D).
01/11/2025
Nanotoxin induces in situ pyroptosis to sensitize aPD1 to ablate metastases in microsattellite stable colorectal cancer
Carrasco-Díaz, LM, Otero-Mateo, M, Alamo, P, Gallardo, A, Virgili, AC, Páez, D, Voltà-Durán, E, Villaverde, A, Vázquez, E, Unzueta, U, Casanova, I, Alba-Castellon, L, Mangues, R. Nanotoxin induces in situ pyroptosis to sensitize aPD1 to ablate metastases in microsattellite stable colorectal cancer. PHARMACOLOGICAL RESEARCH. 2025; 221DOI:10.1016/j.phrs.2025.107982. PMID:41083088. IF:10.500(Q1/1D).
01/11/2025
Prognostic value of pretreatment peripheral blood biomarkers in patients with head and neck squamous cell carcinoma treated with chemo/bioradiotherapy
Sansa, A, Vásquez, R, Valero, C, Vázquez, C, Holgado, A, Gayà, J, Rubio, D, León, X. Prognostic value of pretreatment peripheral blood biomarkers in patients with head and neck squamous cell carcinoma treated with chemo/bioradiotherapy. Clinical & Translational Oncology. 2025; 27(11)DOI:10.1007/s12094-025-03897-y. PMID:40323571. IF:2.500(Q3/6D).
01/11/2025
Wolf's isotopic phenomenon in a patient with T-cell lymphoblastic lymphoma
Vilaseca, VG, Perez, ES, Fabrego, IE, Peral, IL, Prat, AM. Wolf's isotopic phenomenon in a patient with T-cell lymphoblastic lymphoma. MEDICINA CLINICA. 2025; 165(5)DOI:10.1016/j.medcli.2025.107073. PMID:40543401. IF:2.100(Q2/3D).
01/11/2025
Defining the Patient Journey and Identifying Digital Health Solutions in Treatment-Resistant Schizophrenia
Grasa, E, Forment, A, Alonso-Solís, A, Ramalho, L, Roldán, A, Pousa, E, Aussó, S, Berdun, J, Tesoro, AG, Escudero, J, Corripio, I. Defining the Patient Journey and Identifying Digital Health Solutions in Treatment-Resistant Schizophrenia. ACTAS ESPANOLAS DE PSIQUIATRIA. 2025; 53(6)DOI:10.62641/aep.v53i6.1959. PMID:41437755. IF:1.600(Q3/7D).
01/11/2025
Clinical practice guide for nurses that optimizes nurse's comprehensive care of patients undergoing immunotherapy
Serra-Lopez, J, Miranda, A, Soria, A, Lopez, N, Castañon, E, Majem, M. Clinical practice guide for nurses that optimizes nurse's comprehensive care of patients undergoing immunotherapy. Enfermeria Clinica. 2025; 35(6)DOI:10.1016/j.enfcle.2025.502193. PMID:40204238. IF:(Q/D).
01/11/2025
Use of nebulized bronchodilators in acute heart failure: impact on outcomes
Miró, O, Ivars, N, Espinosa, B, Jacob, J, Alquézar-Arbé, A, Gil, V, Bellido, A, Serrano, L, Herrero-Puente, P, Fortuny, MJ, Mir, M, Soy, E, Esquivias, MA, Tost, J, Travería, L, Domingo, E, Noceda, J, López-Diez, MP, Aguirre, A, Alonso, H, Romero, M, López-Grima, ML, López, ML, Mueller, C, Peacock, WF, Puente, PH. Use of nebulized bronchodilators in acute heart failure: impact on outcomes. Internal and Emergency Medicine. 2025; 20(8)DOI:10.1007/s11739-025-04123-x. PMID:41162690. IF:3.800(Q1/2D).
01/11/2025
The MULTISENT Study: A Multicenter Study on the Detection Rate of Sentinel Lymph Node Mapping in Endometrial Cancer Across Spain
Gómez-Hidalgo, NR, Cabrera, S, Bebia, V, García-Pineda, V, Padilla-Iserte, P, Fabregas, FF, Fuste, P, Alonso, P, Rodriguez, TG, Fernandez-Gonzalez, S, Chacon, E, Alvarez, JAP, Oliver, R, Gil-Moreno, A. The MULTISENT Study: A Multicenter Study on the Detection Rate of Sentinel Lymph Node Mapping in Endometrial Cancer Across Spain. ANNALS OF SURGICAL ONCOLOGY. 2025; 32(12)DOI:10.1245/s10434-025-17836-2. PMID:40702200. IF:3.500(Q1/2D).
01/11/2025
Executive summary. Screening, staging and follow-up of type 1 diabetes in preclinical stages: consensus of the scientific societies SED, SEEN and SEEP.
Martinez-Brocca, Maria Asuncion, Bellido, Virginia, Cardona-Hernandez, Roque, Castaño, Luis, Conget, Ignacio, Fernandez, Alberto, Gomez Gila, Ana Lucia, Leiva-Gea, Isabel, Mauricio, Didac. Executive summary. Screening, staging and follow-up of type 1 diabetes in preclinical stages: consensus of the scientific societies SED, SEEN and SEEP.. Anales De Pediatria. 2025; 103(5)DOI:10.1016/j.anpede.2025.503944. PMID:. IF:(Q/D).
01/11/2025
Addition of pulse corticosteroids to oral prednisone in moderately active ulcerative colitis: a randomized, multicentre, open-label study by GETECCU
Llao, J, Mañosa, M, Martín-Arranz, E, Zabana, Y, Navarro-Llavat, M, Téller, M, Garcia-Planella, E, Busquets, D, Monfort, D, Pineda, JR, Gutiérrez, A, Villoria, A, Menchén, L, Bastida, G, García-Alonso, FJ, Rivero, M, Chaparro, M, de Francisco, R, Merino, O, Rodríguez-Lago, I, Acosta, MBD, Rodríguez-Fortúnez, P, Rodríguez-Jiménez, C, Calafat, M, Domènech, E. Addition of pulse corticosteroids to oral prednisone in moderately active ulcerative colitis: a randomized, multicentre, open-label study by GETECCU. Journal of Crohns & Colitis. 2025; 19(11)DOI:10.1093/ecco-jcc/jjaf182. PMID:41258993. IF:8.700(Q1/1D).
01/11/2025
A Metagenomics Approach to Frailty in Patients With Cirrhosis Undergoing a Multifactorial Intervention
Vega-Abellaneda, S, Román, E, Soler, Z, Ortiz, MA, Rossi, G, Biagini, L, Sánchez, E, Pons-Tarin, M, Laghi, L, Mengucci, C, Kaur, N, Poca, M, Cuyàs, B, Serrano-Gomez, G, Alvarado, E, Manichanh, C, Soriano, G. A Metagenomics Approach to Frailty in Patients With Cirrhosis Undergoing a Multifactorial Intervention. LIVER INTERNATIONAL. 2025; 45(12)DOI:10.1111/liv.70418. PMID:41174950. IF:5.200(Q1/2D).
01/11/2025
Consensus on acromegaly therapeutic outcomes: an update
Melmed, S, di Filippo, L, Fleseriu, M, Mercado, M, Karavitaki, N, Gurnell, M, Salvatori, R, Tsagarakis, S, Losa, M, Maffei, P, Pereira, AM, Geer, EB, Katznelson, L, van der Lely, AJ, Bollerslev, J, Esposito, D, Webb, SM, Zatelli, MC, Valassi, E, Neggers, S, Chanson, P, Ho, KKY, Ioachimescu, AG, Biller, BMK, Samson, SL, Kaiser, UB, Schilbach, K, Luque, RM, Casanueva, FF, Shimon, I, Boguszewski, CL, Biermasz, N, Colao, A, Pirchio, R, Lamberts, SWJ, Kadioglu, P, Buchfelder, M, Frara, S, Chiloiro, S, Petersenn, S, Gadelha, MR, Puig-Domingo, M, Luger, A, Brue, T, Beckers, A, Ferone, D, Clemmons, DR, Greenman, Y, Marazuela, M, Mortini, P, Strasburger, CJ, Giustina, A. Consensus on acromegaly therapeutic outcomes: an update. Nature Reviews Endocrinology. 2025; 21(11)DOI:10.1038/s41574-025-01148-2. PMID:40804505. IF:40.000(Q1/1D).
01/11/2025
First-Line Osimertinib in a Patient Having NSCLC With a Rare Duplication Mutation in the EGFR Exon 19 Region (NM_005228.5:c.2214_2231dup p.(Ile740_Lys745dup))
Portu, M, Martinez-Recio, S, Barba, A, Gonzalez, A, López, L, Catasús, L, Majem, M. First-Line Osimertinib in a Patient Having NSCLC With a Rare Duplication Mutation in the EGFR Exon 19 Region (NM_005228.5:c.2214_2231dup p.(Ile740_Lys745dup)). Clinical Lung Cancer. 2025; 26(7)DOI:10.1016/j.clic.2025.07.013. PMID:40774920. IF:3.300(Q2/4D).
01/11/2025
Assessing outcomes emerging after confirmatory trials of accelerated approval drugs, 1992-2021
Cardozo, AR, Tibau, A, Liu, I, Han, J, Cliff, E, Kesselheim, A. Assessing outcomes emerging after confirmatory trials of accelerated approval drugs, 1992-2021. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.2894. PMID:. IF:65.400(Q1/1D).
01/11/2025
Magnitude of clinical benefit demonstrated in trials supporting FDA and EMA Approval of drugs for hematological malignancies, 2020-2024
Cardozo, AR, Kesselheim, A, Tibau, A. Magnitude of clinical benefit demonstrated in trials supporting FDA and EMA Approval of drugs for hematological malignancies, 2020-2024. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.1886. PMID:. IF:65.400(Q1/1D).
01/11/2025
CIRTUSARC: A multicenter, open-label phase II trial of cirtuvivint as second-line therapy in selected advanced soft-tissue sarcomas
Martin-Broto, J, Ospina, GM, Garcia, AS, Trufero, JM, Martinez-Garcia, J, Fidalgo, JAP, Morales, CMV, Jurado, JC, Ledesma, P, Grifman, M, Moura, DD, Muñiz, NH. CIRTUSARC: A multicenter, open-label phase II trial of cirtuvivint as second-line therapy in selected advanced soft-tissue sarcomas. ANNALS OF ONCOLOGY. 2025; 36DOI:10.1016/j.annonc.2025.08.3354. PMID:. IF:65.400(Q1/1D).
01/11/2025
Endoscopic-assisted maxillectomy: our experience in tumours affecting the posterior wall of the maxillary sinus
Casasayas, M, Holgado, A, León, X, Kolanczak, K, Pérez-Sempere, M, Quer, M, Gras-Cabrerizo, JR. Endoscopic-assisted maxillectomy: our experience in tumours affecting the posterior wall of the maxillary sinus. JOURNAL OF LARYNGOLOGY AND OTOLOGY. 2025; 139(11)DOI:10.1017/S0022215125102958. PMID:40734309. IF:0.800(Q3/8D).
01/11/2025
Targeting LDL aggregation decreases atherosclerotic lipid burden in a humanized mouse model of familial hypercholesterolemia: Crucial role of ApoB100 conformational stabilization
Benitez-Amaro, A, Garcia, E, Lhoëst, MTL, Martínez, A, Borrás, C, Tondo, M, Céspedes, MV, Caruana, P, Pepe, A, Bochicchio, B, Cenarro, A, Civeira, F, Prades, R, Escola-Gil, JC, Llorente-Cortés, V. Targeting LDL aggregation decreases atherosclerotic lipid burden in a humanized mouse model of familial hypercholesterolemia: Crucial role of ApoB100 conformational stabilization. ATHEROSCLEROSIS. 2025; 410DOI:10.1016/j.atherosclerosis.2024.118630. PMID:39547850. IF:5.700(Q1/1D).
01/11/2025
Comparative efficacy and safety of Clozapine vs. Quetiapine in schizophrenia and related disorders: An updated systematic review
Asenjo-Lobos, C, Arancibia, M, Garcia-Ribera, C, Cortés-Jofré, M, Huang, TM, Li, T, Madrid, E, Leucht, S. Comparative efficacy and safety of Clozapine vs. Quetiapine in schizophrenia and related disorders: An updated systematic review. PSYCHIATRY RESEARCH. 2025; 353DOI:10.1016/j.psychres.2025.116764. PMID:41101242. IF:3.900(Q1/2D).
01/11/2025
Detection and treatment of early gestational diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials
Garcia-Patterson, A, Balsells, M, Solà, I, Corcoy, R. Detection and treatment of early gestational diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2025; 233(5)DOI:10.1016/j.ajog.2025.04.059. PMID:40320104. IF:8.400(Q1/1D).
01/11/2025
Holistic evaluation of the impact of pregnancy urban exposome on infant wheezing and chest infections: an outcome-wide approach
Sinsamala, RM, Anguita-Ruiz, A, Basagaña, X, Foraster, M, Gascon, M, Llurba, E, Luo, CL, Nieuwenhuijsen, MJ, Persavento, C, Rivas, I, Zhao, Y, Gomez-Roig, MD, Sunyer, J, Marcon, A, Johannessen, A, Dadvand, P. Holistic evaluation of the impact of pregnancy urban exposome on infant wheezing and chest infections: an outcome-wide approach. ENVIRONMENT INTERNATIONAL. 2025; 205DOI:10.1016/j.envint.2025.109900. PMID:41223798. IF:9.700(Q1/1D).
01/11/2025
Long-Term Effectiveness and Safety of Bimekizumab in Patients with Moderate to Severe Hidradenitis Suppurativa Under Real Clinical Practice Conditions: The Importance of Combined Treatment in Hurley III Patients and Potential Factors Associated with Complete Response
Mansilla-Polo, M, García-Moronta, C, Fernández-Crehuet, P, Garbayo-Salmons, P, Pons-Benavent, M, Aguilar-González, L, Jiménez-Gallo, D, Alcalá-García, R, Martín-Ezquerra, G, Martorell, A, Mahiques-Santos, L, Alfageme-Roldán, F, Escutia-Muñoz, B, Sahuquillo-Torralba, A, Fayos-Gregori, R, Soto-Moreno, A, Sánchez-Gutiérrez, I, Botella-Estrada, R, Vilarrasa, E, Molina-Leyva, A. Long-Term Effectiveness and Safety of Bimekizumab in Patients with Moderate to Severe Hidradenitis Suppurativa Under Real Clinical Practice Conditions: The Importance of Combined Treatment in Hurley III Patients and Potential Factors Associated with Complete Response. Dermatology and Therapy. 2025; 15(11)DOI:10.1007/s13555-025-01521-z. PMID:40866757. IF:4.200(Q1/1D).
01/11/2025
The environmental impact of inhalers: a framework for sustainable prescription practices in Spain
Garin, N, Zarate-Tamames, B, Lertxundi, U, da Silva, IM, Orive, G, Crespo-Lessmann, A, de la Rosa, D. The environmental impact of inhalers: a framework for sustainable prescription practices in Spain. EUROPEAN JOURNAL OF HOSPITAL PHARMACY. 2025; 32(6)DOI:10.1136/ejhpharm-2024-004402. PMID:39788701. IF:1.500(Q4/8D).
01/11/2025
Oncological outcomes for patients with European Association of Urology definitions of BCG failure treated with radical cystectomy
Farré, A, Huguet, J, Basile, G, Diéguez, L, Izquierdo, P, Sánchez, R, Gavrilov, P, Gallioli, A, Faba, OR, Gaya, JM, Palou, J, Breda, A. Oncological outcomes for patients with European Association of Urology definitions of BCG failure treated with radical cystectomy. Actas Urologicas Espanolas. 2025; 49(9)DOI:10.1016/j.acuro.2025.501834. PMID:. IF:1.200(Q3/7D).
01/11/2025
Interobserver reproducibility of a hybrid three-tier grading system of papillary nonmuscle invasive urothelial carcinoma: an international Uropathology study
Downes, MR, Lajkosz, K, Algaba, F, Allory, Y, Amin, MB, Cheng, L, Desai, S, Eckstein, M, Hartmann, A, Lopez-Beltran, A, Mannweiler, S, van Montfoort, ML, Oxley, J, Paner, GP, Samaratunga, H, Shen, S, Warrick, J, Williamson, SR, Wobker, SE, van der Kwast, TH. Interobserver reproducibility of a hybrid three-tier grading system of papillary nonmuscle invasive urothelial carcinoma: an international Uropathology study. HISTOPATHOLOGY. 2025; 87(5)DOI:10.1111/his.15438. PMID:40058790. IF:4.100(Q1/1D).
01/11/2025
Active Surveillance of Grade Group 2 Prostate Cancer: Oncological Outcomes from a Contemporary European Cohort
Baboudjian, M, Leni, R, Oderda, M, Peyrottes, A, Kesch, C, Al-Nader, M, Uleri, A, Dariane, C, Baud, H, Olivier, J, Rios, AR, Sanguedolce, F, Benard, V, Windisch, O, Valerio, M, Gandaglia, G, Ploussard, G. Active Surveillance of Grade Group 2 Prostate Cancer: Oncological Outcomes from a Contemporary European Cohort. European Urology Oncology. 2025; 8(5)DOI:10.1016/j.euo.2025.01.009. PMID:39965999. IF:9.300(Q1/1D).
31/10/2025
What is the optimal dose of N-acetylcysteine in adult patients with bronchiectasis?-data from the RIBRON registry
Oscullo, G, Méndez, R, Olveira, C, Giron, R, Garcia-Clemente, M, Máiz, L, Sibila, O, Golpe, R, Rodríguez-Hermosa, JL, Barreiro, E, Prados, C, Rodríguez-Lopez, J, de la Rosa, D, Martinez-Garcia, MA. What is the optimal dose of N-acetylcysteine in adult patients with bronchiectasis?-data from the RIBRON registry. Journal of Thoracic Disease. 2025; 17(10)DOI:10.21037/jtd-2025-1159. PMID:41229849. IF:1.900(Q3/7D).
30/10/2025
Comparing Cytoreductive Nephrectomy with Tumor Thrombectomy Between Open, Laparoscopic, and Robotic Approaches
Sandberg, M, Russell, G, Krol, P, Hayes, M, Bissette, R, Ben David, R, Patel, K, Aljabi, B, Byun, SS, Faba, OR, Marchinena, PG, Mourao, T, Ciancio, G, Peyton, CC, Zanotti, R, Spiess, PE, Mehrazin, R, Rais-Bahrami, S, Abreu, D, Zequi, SD, Rodriguez, AR. Comparing Cytoreductive Nephrectomy with Tumor Thrombectomy Between Open, Laparoscopic, and Robotic Approaches. Cancers. 2025; 17(21)DOI:10.3390/cancers17213490. PMID:41228283. IF:4.400(Q2/3D).
30/10/2025
The association of diabetes with Alzheimer's disease biomarkers and vascular burden across European aging and memory clinic cohorts
Van Gils, V, Jansen, WJ, van der Flier, WM, Martinez-Lage, P, Hort, J, Ramakers, IHGB, Rouaud, O, Laakso, M, Engelborghs, S, Popp, J, Lleó, A, Wallin, A, Tsolaki, M, Teunissen, CE, Vandenberghe, R, Freund-Levi, Y, Frölich, L, Zetterberg, H, Streffer, J, Lovestone, S, Moonen, J, Van Harten, A, Veverová, K, Legdeur, N, Den Braber, A, Damian, D, Hall, A, Bralten, J, Fanelli, G, Franke, B, Poelmans, G, Bulló, M, Jimenez-Murcia, S, Fernandez-Aranda, F, Salas-Salvadó, J, Dalsgaard, S, Visser, PJ, Vos, SJB. The association of diabetes with Alzheimer's disease biomarkers and vascular burden across European aging and memory clinic cohorts. ALZHEIMERS & DEMENTIA. 2025; 21(10)DOI:10.1002/alz.70804. PMID:41165072. IF:11.100(Q1/1D).
30/10/2025
Predictors of response to omalizumab and relapse in chronic spontaneous Urticaria: a narrative review focusing on parameters available in routine clinical practice
Mateu-Arrom, L, Nogueira, XAV, Puig, L, Spertino, J. Predictors of response to omalizumab and relapse in chronic spontaneous Urticaria: a narrative review focusing on parameters available in routine clinical practice. Frontiers In Allergy. 2025; 6DOI:10.3389/falgy.2025.1688464. PMID:41246132. IF:(Q/D).
29/10/2025
Rationale and Methodological Approach Underlying the Development of the Sequential Organ Failure Assessment (SOFA)-2 Score
Moreno, R, Rhodes, A, Ranzani, O, Salluh, JIF, Berger-Estilita, J, Coopersmith, CM, Juffermans, NP, Laffey, J, Reinikainen, M, Neto, AS, Tavares, M, Timsit, JF, Lopez, MDA, Arulkumaran, N, Azoulay, E, Chaudhuri, D, De Lange, D, De Waele, J, Dos Santos, CC, Du, B, Einav, S, Ferrer, R, Fujii, T, Gershengorn, HB, Haniffa, R, Hasan, MS, Hollenberg, S, Ippolito, M, Jung, CS, Kirov, M, Lakbar, I, Lipman, J, Liu, VC, Lobo, SM, Martin, GS, Metnitz, P, Myatra, SN, Oczkowski, S, Paiva, JA, Paruk, F, Pekkarinen, PT, Pilcher, D, Piquilloud, L, Pölkki, A, Prescott, HC, Blaser, AR, Rezende, E, Robba, C, Rochwerg, B, Schenck, EJ, Sendagire, C, Siaw-Frimpong, M, Simpkin, AJ, Soares, M, Summers, C, Szczeklik, W, Takala, J, Vincent, JL, Wendon, J, Zampieri, FG, Shankar-Hari, M, Singer, M. Rationale and Methodological Approach Underlying the Development of the Sequential Organ Failure Assessment (SOFA)-2 Score. JAMA Network Open. 2025; 8(10)DOI:10.1001/jamanetworkopen.2025.45040. PMID:41159829. IF:9.700(Q1/1D).
28/10/2025
ReTAVI Registry: Early Outcomes of Redo-TAVI with SAPIEN Platform in a Real-World Prospective Cohort
Tarantini, G, Fovino, LN, Covarrubias, HA, Wolny, R, Fabris, T, Nawara-Skipirzepa, J, Eden, M, Gomez, JLZ, Joner, M, Cuisset, T, Delgado, V, Rodés-Cabau, J, Saia, F, Bieliauskas, G, Van Belle, E, Modine, T, Rheude, T, Garot, P, Jung, CS, Rudolph, T, Leroux, L, Rottbauer, W, Nestelberger, T, Lhermusier, T, Nejjari, M, Regueiro, A, Meier, D, Fraccaro, C, Hartikainen, TS, Karam, N, Swaans, M, Rodrigues, JA, Dreger, H, Hengstenberg, C, Choudhury, D, Mauler-Wittwer, S, Piazza, N, Combaret, N, Letocart, V, Auffret, V, Durand, E, Urena, M, Del Valle, R, Drago, A, De Carlo, M, Diaz, VAJ, Dabrowski, M, Mascherbauer, J, Sudre, A, Ong, P, Gonska, B, Mancone, M, Fabris, E, Teles, R, Nombela-Franco, L, Asmarats, L, Vilalta, V, Protasiewicz, M, Webb, J, Toth, G, Zierer, A, Rioufol, G, Seiffert, M, Adamo, M, Meucci, F, Ielasi, A, Burzotta, F, Lopez, M, Loewenstein, I, Kralisz, P, Legutko, J, Huczek, Z, Pavei, A, Rakova, R, Wesselink, W, Zielinski, M, Greinert, D, Trushina, N, Zimmermann, L, Bramlage, P, Parma, R. ReTAVI Registry: Early Outcomes of Redo-TAVI with SAPIEN Platform in a Real-World Prospective Cohort. JACC-JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2025; 86(17)DOI:. PMID:. IF:22.300(Q1/1D).
28/10/2025
Effect of DAPAgliflozin on Myocardial Fibrosis and Ventricular Function in Patients with ST-Segment Elevation Myocardial Infarction: the DAPA-STEMI Trial
Laudani, C, Ortega-Paz, L, Sionis, A, Calés, PV, Arevalos, V, Riba, RA, Morr, C, De Diego, O, Ortega, E, Dantas, AP, Angiolillo, D, Sabate, M, Ortiz-Pérez, JT, Brugaletta, S. Effect of DAPAgliflozin on Myocardial Fibrosis and Ventricular Function in Patients with ST-Segment Elevation Myocardial Infarction: the DAPA-STEMI Trial. JACC-JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2025; 86(17)DOI:. PMID:. IF:22.300(Q1/1D).
28/10/2025
POINTER: study protocol for a phase 2b, randomised, placebo-controlled, double-blind, parallel group dose-finding clinical study to evaluate the efficacy of RMC-035 on renal function and safety, in participants at high risk for kidney injury, following open-chest cardiac surgery
Zarbock, A, Strauss, C, Laflamme, M, Myjavec, A, Böhm, J, Burkert, J, Mazer, CD, de Varennes, B, Ginel Iglesias, A, Matschke, K, Larsson, TE, Reusch, M. POINTER: study protocol for a phase 2b, randomised, placebo-controlled, double-blind, parallel group dose-finding clinical study to evaluate the efficacy of RMC-035 on renal function and safety, in participants at high risk for kidney injury, following open-chest cardiac surgery. Trials. 2025; 26(1)DOI:10.1186/s13063-025-09124-x. PMID:41152991. IF:2.000(Q3/7D).
25/10/2025
Prevalence and evolution of hypertension in a large Iberian cohort of patients with acromegaly
Araujo-Castro, M, García-Centeno, R, González, L, Nobre, EL, Severino, MD, Goi, J, Pena, MMP, Torre, EM, Aida, CL, Novoa-Testa, I, Cordido, F, Sánchón, R, Guerrero-Pérez, F, Rodríguez, RO, Rodríguez-Jiménez, B, García, MDO, Echarri, AI, Simó-Servat, A, Rodríguez, MDM, Novo-Rodríguez, C, Calatayud, M, Villar-Taibo, R, Bernabéu, I, Tenorio-Jimenéz, C, Molero, IG, Iglesias, P, Blanco, C, De Lara, FVO, Aulinas, A, Roca, QA, Fano, MP, Martínez, AR, Cardoso, LM, Marques, P, Giustina, A, Marazuela, M, Puig-Domingo, M, Biagetti, B. Prevalence and evolution of hypertension in a large Iberian cohort of patients with acromegaly. Pituitary. 2025; 28(6)DOI:10.1007/s11102-025-01586-1. PMID:41139153. IF:3.400(Q2/4D).
25/10/2025
Real-World Data on the Efficacy and Safety of Osilodrostat in Patients with Cushing's Disease in Spain
Araujo-Castro, M, García-Centeno, R, González, L, Hanzu, FA, Orois, A, Camara, R, García, MDO, Echarri, AI, Gimeno, PG, Pascual-Corrales, E, Biagetti, B, Cardona, A, Molero, IG, Simo-Servat, A, Pérez, FG, Villar-Taibo, R, Bernabéu, I, Fajardo-Montañana, C, Novo-Rodríguez, C, Jimenéz, CT, Calatayud, M, Rodríguez, MDM, Cordido, F, Castro, A, Valero, LM, Fano, MP, Goi, J, Aulinas, A, Abellán, P, Iglesias, P, Soto-Moreno, A. Real-World Data on the Efficacy and Safety of Osilodrostat in Patients with Cushing's Disease in Spain. Journal of Clinical Medicine. 2025; 14(21)DOI:10.3390/jcm14217575. PMID:41226972. IF:2.900(Q1/2D).