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Institut de Recerca Sant Pau - Centre CERCA
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Strategic Areas and Transversal Programmes
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Welcome to the Institut de Recerca Sant Pau
RESEARCH
Descobreixen com un bacteri respiratori obté lípids essencials de l’organisme humà i es dirigeix a teixits rics en greix

Researchers Discover How a Respiratory Bacterium Obtains Essential Lipids From the Human Body and Targets Fat-Rich Tissues

A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae—responsible for atypical pneumonia and other respiratory infections—to obtain cholesterol and other essential lipids directly from the human body. The discovery has been published in Nature Communications.

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RESEARCH
Dr. Ignacio Illán i Dra. Sara Rubio

New Neuropsychological Reference Standards Enable Earlier Detection of One in Five Incipient Alzheimer’s Disease Cases

The Sant Pau Research Institute (IR Sant Pau) has led a multicenter project that redefines what is considered normal cognitive performance. The work, carried out in collaboration with Hospital Clínic de Barcelona, Hospital Universitario Marqués de Valdecilla in Santander, and the CITA-Alzheimer Foundation in San Sebastián, has resulted in two complementary scientific articles published in the journal Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring (DADM), which establish new cognitive reference standards based exclusively on individuals without amyloid pathology and demonstrate their ability to improve early diagnosis.

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RESEARCH
Diego del Castillo_Àlex Bayés_Oriana Victoria Zerpa

A Study Reveals How Hippocampal Synapses Adjust Their Proteins to Specialize Their Function

A research team led by Dr. Àlex Bayés, Head of the Molecular Physiology of the Synapse Group at the Institut de Recerca Sant Pau (IR Sant Pau), has achieved what for decades had been an elusive goal: obtaining a precise, differentiated molecular portrait of individual synaptic types in the hippocampus, the brain structure that serves as the core of learning and memory.

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HIGHLIGHTS
2025 David González

David González Gil Joins IR Sant Pau as New General Manager

The Sant Pau Research Institute (IR Sant Pau) has appointed David González Gil as its new general manager, a nomination approved by the Foundation’s Board of Trustees at its extraordinary session on October 6. David González officially took office on December 9, with the aim of driving a new phase of growth and consolidation for the center.

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HIGHLIGHTS
2025 XWHIN

Birth of XWHIN, the Catalan Network for Women’s Health Innovation Applying a Sex and Gender Perspective, Led by IR Sant Pau

The new XWHIN (Women’s Health Innovation Network), coordinated by the Institut de Recerca Sant Pau (IR Sant Pau), has been established with the support of the Agency for the Management of University and Research Grants (AGAUR), which has awarded funding of 1 million euros under the Xarxes d’R+D+I 2025 call. This initiative represents a recognition of IR Sant Pau’s leadership in responsible research with a gender perspective and strengthens its role as a key player in Catalonia’s health R&D&I ecosystem.

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