TRANSLATIONAL MEDICINE

Nephrology

Main lines of research

Proteomics Applied to Nephrology and Hypertension

  • Water and sodium renal transport analysed from urinary exosomes, urinary proteomic characterization in diabetic nephropathy: evaluation of renal-angiotensin blockade.

Hereditary Kidney Diseases

  • Genetic and clinical studies in cystic and glomerular inherited kidney diseases such as polycystic kidney disease, Alport, corticoid-resistant nephrotic syndrome, Fabry disease, tuberous sclerosis and familial nephropathies of uncertain origin.

Glomerular Disorders

  • Molecular and clinical studies in disorders such as membranous glomerulopathy and vasculitis with renal involvement, among others.

Kidney Transplantation

  • Protocol biopsies, chronic transplant nephropathy, kidney transplant and associated cardiovascular risk factors, pharmacogenetic and genomic studies.

Chronic Kidney Disease (CKD)

  • Early diagnosis of CKD, epidemiological and clinical studies in CKD-related complications such as renal anaemia, CKD mineral and bone disorders (CKD-MBD) and associated cardiovascular risk; haemodialysis techniques and studies of genetic damage in patients with CKD.
  • Mechanisms of epithelial-mesenchymal transition and renal fibrosis.

Challenges

  • Maintain the level of national and international publication.
  • Continue with both clinical and basic research in all the previously described areas.
  • Participate in the elaboration of clinical nephrology guidelines.
  • Continue with active collection of research samples from CKD and transplant patients.
  • Maintain participation in national working groups and increase international cooperation.
  • Engage in new pharmaceutical clinical studies, including clinical trials.

Grup consolidat de l’Institut d’Investigació Biomèdica Sant Pau que pertany a

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