NEWS





IR Sant Pau Study Reveals Immune System’s Crucial Role in ALS at Cellular Level

A team of researchers from the Sant Pau Research Institute (IR Sant Pau) has published a study in the Journal of Neuroinflammation that, for the first time, examines in depth the role of the peripheral immune system in amyotrophic lateral sclerosis (ALS) at the single-cell level. Their findings suggest that immune system cells—particularly two subpopulations of Natural Killer (NK) cells—may play a crucial part in the development and progression of this neurodegenerative disease.

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More than 2,500 People Celebrate the Women and Girls in Science Festival with Mariona and Sant Pau

As part of the celebration of the International Day of Women and Girls in Science, on Sunday, 9th February, more than 2,500 people enjoyed the Women and Girls in Science Festival, an event organised by the Sant Pau Research Institute (IR Sant Pau) to bring science closer to everyone and to encourage scientific vocations among girls and young people. The Panoramic Area of Tibidabo Amusement Park was transformed into a large open-air laboratory, where researchers shared their passion with the public through experiments, workshops, and interactive activities.

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L’IR Sant Pau aconsegueix una ajuda d’1,4 milions d’euros per millorar la seva Unitat d’Investigació Clínica

L’Institut de Recerca Sant Pau (IR Sant Pau) ha estat beneficiat amb una ajuda d’1.406.625 euros per part de l’Institut de Salut Carlos III de Madrid (ISCIII). Aquest suport econòmic es destinarà a modernitzar i millorar la Unitat d’Investigació Clínica del centre, reforçant la seva capacitat per dur a terme estudis d’alta qualitat i donar resposta a les necessitats dels pacients. L’ajuda s’emmarca en un projecte de l’ISCIII per impulsar la investigació a Espanya, tant mitjançant la millora de les unitats ja existents com amb la creació de noves.

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The Sant Pau Research Institute Hosts a New Edition of Its Research Day

One more year, the Sant Pau Research Institute (IR Sant Pau) celebrated a new edition of its Research Day, an event aimed at reaffirming the center’s position as a leader in biomedical research and scientific innovation. The gathering brought together research leaders, healthcare professionals, and technology experts to discuss the latest advancements transforming healthcare.

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High Mountains and Research Join Forces to Fight Thrombosis

What connection could there possibly be between thrombosis, a severe disease that causes one death every minute in Europe, and high-altitude mountains? Much more than we might imagine. At high altitudes, environmental conditions such as hypoxia and extreme physical effort can trigger physiological responses that increase the risk of blood clot formation, a situation similar to what people affected by thrombosis experience.

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The Sant Pau Research Institute Leads a Pioneering Clinical Trial to Treat Cancer in Patients with Fanconi Anemia

The Sant Pau Research Institute (IR) will launch a new Phase I/IIB clinical trial for patients with Fanconi anemia diagnosed with head and neck cancer. The study, known as the AFAN trial (EU CT No.: 2024-511477-29-00), is led by Dr. Jordi Surrallés, head of the Cancer Predisposition Syndromes Group, scientific director of the IR Sant Pau, and professor in the Department of Genetics and Microbiology at the UAB.

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A Study by Sant Pau Reveals That Emotional State and Stress During the COVID-19 Lockdown Affected Women’s Menstrual Cycle Patterns

A recent study published by researchers from the Reproductive Health Group of the Sant Pau Research Institute (IR Sant Pau) and the Gynecology and Obstetrics Service of Sant Pau Hospital concludes that there is a clearly direct and significant relationship between the intensity of changes in emotional state due to stress factors during the COVID-19 pandemic lockdown and the incidence of menstrual changes: regularity, duration, and amount of menstruation.

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Sant Pau and the Tibidabo Amusement Park Join Forces to Promote Scientific Vocations and Scientific Dissemination with a Gender Perspective

The Sant Pau Research Institute (IR Sant Pau) and the Tibidabo Amusement Park have signed a collaboration agreement to promote the dissemination of gender-focused research and encourage scientific vocations among the young, with the central theme being the celebration of the International Day of Women and Girls in Science in February 2025. This agreement demonstrates the shared commitment of both entities to promote a more equitable society aware of the importance of science and the role of women in this field and to drive a project that combines science, gender perspective, fun, and outreach.

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Sant Pau researchers discover a new gene that causes ALS

Researchers from the Neuromuscular Diseases Group and the Dementia Neurobiology Group of the Sant Pau Research Institute (IR Sant Pau) and the Memory Unit of the Sant Pau Hospital, led by neurologist Dr. Ricard Rojas-García, have identified a new mutation in the ARPP21 gene that could be the cause of Amyotrophic Lateral Sclerosis (ALS), a devastating neurodegenerative disease.

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Sant Pau Lays the Cornerstone of the New Advanced Therapies Unit, Reaffirming its Global Leadership in this Field

The Sant Pau Research Institute celebrated today the laying of the cornerstone of its new Advanced Therapies Unit. These new facilities, supported by the Josep Carreras Leukaemia Research Institute and the Josep Carreras Foundation against Leukaemia, solidify themselves as a strategic resource for the Sant Pau Campus. They enable the development and manufacturing of personalized biological medicines within the hospital center for the treatment of its patients, reaffirming Sant Pau’s position as a global reference center in this field.

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Researchers at Sant Pau Identify a New Genetic Form of Alzheimer’s Disease

Researchers from the Research Area on Neurological Diseases, Neuroscience, and Mental Health at the Sant Pau Research Institute, led by Dr. Juan Fortea, Director of the Memory Unit of the Neurology Service at the same hospital, have found that over 95% of individuals over 65 years old who have two copies of the APOE4 gene -APOE4 homozygotes- show biological characteristics of Alzheimer’s pathology in the brain or biomarkers of this disease in cerebrospinal fluid and PET scans.

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A new research group on artificial intelligence applied to medicine is born at Sant Pau

The Sant Pau Research Institute announces the creation of the new research group in Advanced Medical Imaging, Artificial Intelligence, and Image-Guided Therapy. Dr. Josep Munuera, a researcher with a broad trajectory in the use of artificial intelligence applied to medicine and director of the Radiodiagnosis Service at Hospital Sant Pau, will lead this cross-sectional and multidisciplinary project that seeks to go beyond traditional specializations.

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Magnetic resonance surveillance reduces mortality in women at high risk of BRCA1 breast cancer as an alternative to preventive mastectomy

According to the results of an international study involving researchers from the Clinical Oncology group at the Sant Pau Research Institute, led by Dr. Teresa Ramon y Cajal, the follow-up with magnetic resonance imaging in women with mutations in the BRCA1 genes who have a high risk of developing breast cancer throughout their lives significantly reduces mortality without the need for preventive mastectomy.

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