On Wednesday, April 30, at 6 pm, Gerard Muñoz-Pujol, postdoctoral researcher at IR Sant Pau within the DNA Repair Syndromes and Cancer Predisposition research group, will give a talk at the Guinardó Civic Centre entitled ‘DNA scissors: how do we edit the genome in the laboratory?’.
Many diseases have a genetic origin, but the exact cause is often unknown, making diagnosis a real challenge and forcing people to endure a diagnostic odyssey. To diagnose such a disease, it is necessary to analyse DNA to detect the responsible mutations. However, we often encounter variants of uncertain significance, where we do not know if they are actually the cause of the disease. How can we prove it?
In this talk, we will explore how research helps to identify potential genetic alterations in some of these diseases using genome sequencing technologies, and how we use genetic editing tools such as ‘DNA scissors’, also known as CRISPR technologies, to generate genetically edited cell models and study these mutations.
Address: Rda. Guinardó, 113-141 Barcelona 08043
Time: 18:00 h – 19:00 h
