Next January 31 at 7 p.m., Dr. Javier Briones, director of the Cell Immunotherapy and Gene Therapy Research Group at the Research Institute of the Hospital de la Santa Creu i Sant Pau – IIB Sant Pau and head of the Clinical Hematology Unit of the Service d ‘Hematology of the same hospital, participates in the CaixaResearch Debate “What are CAR-T therapies against cancer?” to explain the latest developments in this area. The debate will be moderated by Beatriz Pérez, journalist at El Periódico de Catalunya, and will be streamed and you can sign up here.
The group of Dr. Briones led the creation of the first CAR-T in Europe for patients with classic Hodgkin’s lymphoma and non-Hodgkin’s lymphoma, a disease that affects 3 out of every 100,000 people according to data from the Spanish Society of Medical Oncology. In fact, Sant Pau is one of the only two authorized centers in Catalonia to produce these types of medicines.
It has also recently successfully presented the results of the first CAR-T30 clinical trial in Europe, of its own production, for the treatment of this type of cancer in relapse or refractory. The objective of this Phase I study, in which 10 patients refractory to all approved conventional treatments from various spanish communities and other european countries have participated, has been safety and establishing the optimal dose for Phase II of the essay. The results obtained show that all patients have shown a favorable response to the treatment, while 50% have had a complete response with the disappearance of the lymphoma, so that HSP-CAR30 has an excellent safety profile at the doses administered
In the CaixaResearch Debate “What are CAR-T therapies against cancer?”, together with Dr. Briones, Dr. will also participate Dr. Manuel Juan, head of the Immunology Service at the Biomedical Diagnostic Center (CDB) of the Hospital Clínic-IDIBAPS, who has developed the first CAR-T in Europe for the treatment of multiple myeloma, which accounts for 10% of cancers bone marrow and is the second most common blood cancer.
In the CaixaResearch Debates cycle, the medical and scientific experts who receive grants from the “la Caixa” Foundation, through the Research Program, explain first-hand the latest developments in their field. These debates are a meeting point between society and research results, new medical practices and current challenges in health and quality of life.
