NEWS

Webinar IRISCAT- Dr. Javier Briones “Assaigs Clínics amb CarT Cells per càncers hematològics”

Wednesday, April 21st. 2021 – 16:00

La inmunoterapia adoptiva con células T (IAT) ha sido objeto de investigación desde hace más de 20 años. Una variante de la inmunoterapia adoptiva con células T consiste en la modificación genética de dichas células con receptores T antígeno-específicos (terapia CART). Estas técnicas presentan claras ventajas, pero hay algunos problemas metodológicos que impiden su aplicación clínica a pacientes con cáncer.

Para evitar estos problemas, se ha desarrollado un procedimiento de inmunoterapia con células T mediante su modificación genética con receptores quiméricos antígeno-específicos (ampliamente conocidos con el acrónimo anglosajón “CARs”). Un CAR está constituido por un anticuerpo monoclonal, que reconoce un antígeno, unido al dominio de señalización intracelular de la cadena z del complejo CD3 y una molécula coestimuladora.

En la clínica, el mayor impacto hasta la fecha se ha obtenido con CARs dirigidos frente a CD19. La extraordinaria experiencia obtenida en estos pacientes ha llevado a la aplicación de la terapia CART dirigidas a dianas diferentes a CD19, para el tratamiento de otras neoplasias hematológicas. Los avances obtenidos en los últimos 5 años en el campo de la inmunología antitumoral han permitido colocar a la inmunoterapia en primera línea en el tratamiento de neoplasias hematológicas, lo cual supone un cambio radical en el diseño de los tratamientos, focalizados en las células del sistema inmune en vez de las propias células tumorales.

Dr. Javier Briones

Licenciado en Medicina y Cirugía por la Universidad de Santiago. Realizó la especialidad de Hematologia y Hemoterapia (MIR) en el Servicio de Hematología del Hospital Clínic de Barcelona. Doctor en Medicina por la Universidad de Barcelona. Realizó una estancia posdoctoral en la Universidad de Stanford (USA), en el laboratorio del Dr. Ron Levy, donde desarrolló proyectos sobre vacunas celulares y terapia génica en linfoma (1999-2001).

En la actualidad el Dr. Briones es Profesor Asociado de Medicina (Hematología) en la Universidad Autónoma de Barcelona, y Jefe de la Unidad de Hematología Clínica del Hospital Santa Creu i Sant Pau (Barcelona). Dirige el Programa de Inmunoterapia Celular en Neoplasias Hematológicas y es IP de varios proyectos nacionales e Internacionales en células CART en el IIB Sant Pau. Su grupo de investigación desarrolla CARs académicos para el tratamiento de neoplasias linfoides, el primero de los cuales (HSPCAR30) ha sido autorizado por la Agencia Española del Medicamento (ensayo CART30 para el linfoma de Hodgkin).

Registration


Xerrada al CC Guinardó: Beneficis dels probiòtics sobre la qualitat de vida de las persones

Dra. Eva Román, Infermera i Investigadora CIBERehd, Grup de recerca en Patologia Digestiva de l’Institut de Recerca Hospital de la Santa Creu i Sant Pau – IIB Sant Pau

La microbiota és el conjunt de microorganismes que se es troben en el nostre cos: la boca, els pulmons, els budells, les mucoses dels genitals, la pell… Quan parlem de microbiota intestinal ens referim al conjunt de bactèries presents al tub digestiu i que tenen unes funcions importantíssimes en la salut i la malaltia. Els probiòtics poden modular la microbiota intestinal, la permeabilitat intestinal i la resposta immune i per tant, podrien millorar la funció cognitiva i la qualitat de vida en les persones amb malalties hepàtiques.

La Fundació Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau- IIB Sant Pau mitjançant la seva unitat de cultura científica (UCC+i Fecyt), promou aquest cicle.

– Inscripcions.

07/04/21 a les 19:00 h


Conference: Per a preparar-te el dia de la teva operació, utilitzaries una app mòbil? a càrrec de Miriam Armora

March 23rd, 2021, 18:30 from Centre Cívic Navas

 streaming: facebook.com/CCNavas/

Every patient who has to undergo surgery requires preoperative preparation in the days before the intervention.

“PreparatB” is a smartphone application created for improving pre-operative set up under a doctoral thesis. This session will explain how the application was created and in what state the research project is




Dr. Julve participates in the talks at the Centre Cívic Guinardó

On Wednesday 20 January at 7 pm, Dr. José Julve, researcher from the Cardiovascular Risk Metabolic Basis Research Group at the Sant Pau Research Institute – IIB Sant Pau will give a talk on “The anti-obesity effect of bioactive forms of vitamin B3” at the Guinardó Civic Centre. This lecture is part of the series of free seminars offered by the Research Institute at the civic centres with the aim of showing scientific advances in biomedicine and their importance in clinical practice, diagnosis and therapy of different diseases.

More information

 


Dr. Julve will give the next session of Science Mondays

Dr. José Julve, the researcher in charge of the Miguel Servet programme (Carlos III Health Institute) at the Hospital de la Santa Creu i Sant Pau Research Institute – IIB Sant Pau will give the next session of “Science Mondays” with the lecture entitled “Anti-inflammatory potential of NAD+ precursor molecules in experimental models of diabetes mellitus”. The conference will take place on Monday 30 November at 6 p.m.

More information


Dr. Olivé will give the next session of the Mondays of Science

 

Next Monday, November 23, at 6 pm, the conference will be held: “The long road to describe a new muscle disease” by Dr. Montse Olivé Plana. Dr. Olivé is a member of the Neuromuscular Diseases Research Group of the Sant Pau Research Institute – IIB Sant Pau and a specialist in the Neuromuscular Diseases Unit of the Sant Pau Hospital’s Neurology Service. This session is part of the Science Monday cycle and will be streamed.

More information


Amalia Sillero participates in the conferences on health of Navas Civic Center

On November 18, at 6.30 pm, Dr. Amalia Sillero, surgical nurse at the Hospital de Sant Pau and researcher of the Nursing Care Research Group of the Sant Pau Research Institute – IIB Sant Pau, will give a lecture on “The application of the values of magnetism in the surgical area of a high-tech hospital”, the subject of her doctoral thesis. The session will be done in streaming.

més…


Dr. Soria will give the next Science Mondays conference

On 16 November at 6 pm, Dr. José Manuel Soria, head of the Genomics of Complex Diseases Research Group at the Sant Pau Research Institute – IIB Sant Pau and scientific director of Exheus, will give the conference “Risk of thrombosis associated with Covid-19”. For more information, see the programme with the next conferences in the cycle.

 

més…


Dr. Domingo will give one of the IRISCAT seminars focused on the Covid-19

Dr. Pere Domingo, Covid-19 coordinator of the Hospital and coordinator of the HIV and AIDS Research Group of the Sant Pau Research Institute-IIB Sant Pau, will give the webinar “Covid-19 pharmacological interventions” today, 4 November. This seminar forms part of the joint scientific dissemination action of the Alliance of Health Research and Innovation Institutes of Catalonia (IRISCAT), which has organised a series of webinars that will deal with different topics related to biomedical research and Covid-19. The appointment is at 4 pm and registration is free.

Registration is free

 


Laparoscopic Gastric Surgery Masterclass

On 5 and 6 November, the “Masterclass in Laparoscopic Gastric Surgery” course will be held at the Hospital de Sant Pau with the aim of presenting the techniques and resources needed for the laparoscopic approach to the stomach, both in complex malignant and benign pathology. Making a bet adapted to the pandemic, the essence of surgery will be kept with a live 3D broadcast at the Olympus Iberia headquarters. Attached you will find the course program.

Program Masterclass


Science Monday with Dr Antonijoan

On 2 November at 6 p.m., Dr Rosa M. Antonijoan, director of the CIE-Sant Pau of the Research Institute of the Hospital de la Santa Creu i Sant Pau – IIB Sant Pau and head of the Clinical Pharmacology Service of the Hospital, will give the session “Clinical Trials. The way forward for diseases” as part of the Science Monday cycle.

més…


The Sant Pau Research Institute participates in the Barcelona City Council health conferences

The researchers of the Sant Pau Research Institute-IIB Sant Pau, Elena Jiménez and Raquel Delgado, will be giving the second conference of World Stroke Day 2020 at the Guinardó Civic Centre on 29 October as part of the TV3 Marathon research at the IR Sant Pau. The session will focus on knowing how to recognise a stroke and the factors that can produce it and how this can save lives. At the same time, knowing what to do after having suffered one can help to improve the quality of life.

més…


4th edition – Summer School Spanish Edition

The Research Institute of the Hospital de Sant Pau (IIB Sant Pau) collaborates in the organization of the Summer School Spanish Edition – 4th edition, promoted by the Department of Health, CatSalut and the Minority Diseases Platform and invites you to participate in order to make this edition aimed at researchers and patients a success.

The aim of this course is to immerse participants in the process of living a drug, from its designation to its approval in the market.


545/5000 Triple A (AAA): The silent killer of Albert Einstein

Triple A (AAA): The silent killer of Albert Einstein
Next Tuesday, January 28, at 7 pm, Dr. Cristina Rodríguez-Sinovas, researcher and coordinator of the Research Group on Regulatory Mechanisms of Cardiovascular Remodeling of the Research Institute of the Hospital de la Santa Creu i Sant Pau – IIB Sant Pau, will give the talk “La triple A (AAA) : The silent killer of Albert Einstein. ” This session is part of the Guinardó Civic Center’s project, Classroom 141, to bring science closer to its citizens.

More information here


Pheochromocytoma-paraganglioma carotid Refresher Course

The Biochemistry and Endocrinology and Nutrition Services of the Sant Pau are organising an Update Course on Pheochromocytoma-paraganglioma carotidis on the afternoon of 16 January 2020 in the multipurpose rooms. Further information, including registration information, is available in the enclosed leaflet.


Science Monday with Josep M. Guerra

On Monday 9 December, a new Monday science session will be held by Dr. Josep M. Guerra, coordinator of the Cardiovascular, Cardiology and Translational Clinical Diseases group at the Sant Pau Sant Pau-IIB Research Institute with the title “Arrhythmias and sudden death in the 21st century”. The appointment is at 6.30 pm in the amphitheatre of the Residence for Researchers, CSIC-Generalitat de Catalunya.

More information

 

 


New Science Monday Lectures

Next Monday, December 2, a new Monday science session will be held by Dr. José Julve, from the group of Metabolic Bases of Cardiovascular Risk of the Research Institute of San Pau-IIB Sant Pau with the title “Vitamin B3: anti-obesity effect of a minority nutrient”. The appointment is at 6.30 pm in the amphitheatre of the Residence for Researchers, CSIC-Generalitat of Catalunya.


The Dra. Bortolozzi will impart the next IIB Sant Pau seminar

The Sant Pau Biomedical Research Institute (IIB Sant Pau), in collaboration with the Clinical Psychiatry Research Group led by Dr. Maria J. Portella, organizes the seminar “Ventral cingulate cortex, astrocytes and major depressive disorder. Development of a preclinical model “by Dr. Analia Bortolozzi, titular scientist of the Institute of Biomedical Research of Barcelona (IIBB) CSIC, IDIBAPS. The conference will be on Wednesday, October 9 at 3 pm, in the multipurpose rooms of the Hospital.


This website uses cookies to improve the browsing experience and perform analytical tasks. If you continue browsing, we understand that you agree our cookies policy. More information