Sant Pau - Institut de Recerca

Principals línies de recerca

Asma

Exacerbacions d’asma.
Asma sever.
Guies de bones pràctiques clíniques per asma.
Inflamació bronquial.
Asma experimental i mecanismes patogènics.
Biobancs multicèntrics especialitzats en biòpsies bronquials per la recerca en asma.
Termoplàstia bronquial.
Assajos clínics.

Malaltia pulmonar obstructiva crònica (MPOC) i la insuficiència respiratòria

Respiració mecànica no invasiva.
Rehabilitació respiratòria.
Patofisiologia.
Exacerbació.

Síndrome d’Apnea-Hipopnea del Son (SAHOS)

Fisiologia i conseqüències terapèutiques clíniques de SAHOS.
Síndrome de la hipoventilació per obesitat.
Inflamació de les vies respiratòries i SAHOS.

Reptes

Consolidar una unitat de lideratge en assajos clínics per malalties respiratòries.
Captació de contractes amb la indústria farmacèutica i biotecnològica per desenvolupament preclínic, utilitzant les capacitats del nostre laboratori de recerca bàsica i els models animals experimentals.
Reclutament de personal investigador en formació per la realització de doctorat.
Suport al desenvolupament de xarxes de recerca multidisciplinàries com la Xarxa Respiratòria de Barcelona i el Programa Integrat de Recerca en Asma de la Societat Espanyola de Pneumologia i Cirurgia Toràcica (SEPAR) i col·laboració o involucració del grup en xarxes ja existents, com CIBER-ES (malalties respiratòries).

2017 Scientific Report – Chronic

Coordinació del grup

PLAZA MORAL, VICENTE FGS
vplaza@santpau.cat

Co-coordinador:

Ramos Barbon, David FGS
dramosb@santpau.cat

Membres

Alonso Leon, Ana Maria FGS
Anton Albisu, Pedro Antonio FGS
Castillo Villegas, Diego FGS
Crespo Lessmann, Astrid Del Carmen FGS
De La Rosa Carrillo, David FGS
Fortuna Gutierrez, Ana Maria FGS
Gimenez Palleiro, Ana Maria FGS
Gutierrez Pereyra, Fernando FGS
Gutierrez Rouco, Marta FGS
Mateus Medina, Eder Fredy IR
Mayos Perez, Mercedes FGS
Pajares Ruiz, Virginia FGS
Palones Femenia, Esther FGS
Panadero Paz, Carolina IR
Paz Del Rio, Luis Daniel FGS
Peiro Fabregas, Meritxell FGS
Peñacoba Toribio, Patricia FGS
Podzamczer Valls, Ines FGS
Puy Rion, Maria Carme FGS
Rafecas Codern, Albert FGS
Segura Medina, Macarena FGS
Solanes Garcia, Ingrid FGS
Soto Retes, Lorena Concepcion FGS
Torrego Fernandez, Alfonso FGS

Publicacions 2022

(JIF 2022)

Agusti A, De Stefano G, Levi A, Munoz X, Romero C, Sibila O, Lopez A, Moral VP, Curto E, Echazarreta AL, Marquez SE, Pascual S, Santos S, Marin A, Valdes L, Saldarini F, Salgado C, Casanovas G, Varea S, Rios J, Faner R. Add-on inhaled budesonide in the treatment of hospitalised patients with COVID-19: a randomised clinical trial. EUROPEAN RESPIRATORY JOURNAL. 2022; 59(3):2103036. DOI:10.1183/13993003.03036-2021. PMID:35144989. IF:24,3 (Q1/1D). Document type: Letter.
Alfonsi C, Stephan C, Cortes E, Palacios NJ, Podzamczer I, Cruz NG, Jimenez MRD, Mico SI, Vila MT, Jeltsch K, Hubschmann OK, Opladen T, Fragua RV, Gomez T, Fortuny OA, Jimenez IG, Laso EL, Martinez AR, Lopez JM, Garcia A. Volumetric study of brain MRI in a cohort of patients with neurotransmitter disorders. NEURORADIOLOGY. 2022; 64(11). DOI:10.1007/s00234-022-02989-8. PMID:35662359. IF:2,8 (Q2/5D). Document type: Article.
Alvarez FJ, Blanco M, Casas F, Plaza V, González FJ, Carretero JÁ, Castilla M, Cisneros C, Diaz D, Domingo C, Martínez E, Muñoz X, Padilla A, Perpiñá M, Soto G. Consensus document for severe asthma in adults. 2022 update. Open Respiratory Archives. 2022; 4(3):100192. DOI:10.1016/j.opresp.2022.100192. Document type: Article.
Badenes D, Rodo A, Castillo D, Vicens V, Bermudo G, Hernandez F, Portillo K, Martinez J, Chalela R, Caguana O, Sellares J, Molina M, Duran X, Gea J, Rodriguez DA, Balcells E. Predictors and changes of physical activity in idiopathic pulmonary fibrosis. BMC Pulmonary Medicine. 2022; 22(1):340. DOI:10.1186/s12890-022-02134-4. PMID:36085057. IF:3,1 (Q3/7D). Document type: Article.
Baptista L, Rodrigo JM, Mínguez P, Valverde M, Arismendi E, Barranco P, Barroso B, Bobolea I, Cañas JA, Cárdaba B, Cruz MJ, Curto E, Domínguez J, García R, González FJ, Martínez C, Mullol J, Muñoz X, Olaguibel JM, Picado C, Plaza V, Quirce S, Rial MJ, Sastre B, Soto L, Valero A, del Pozo V, Sastre J. Anxiety and body mass index affect asthma control: data from a prospective Spanish cohort. Journal of Allergy and Clinical Immunology-In Practice. 2022; 10(3). DOI:10.1016/j.jaip.2021.10.013. PMID:34673289. IF:9,4 (Q1/1D). Document type: Letter.
Bermudo G, Suarez G, Rivera P, Rodriguez JA, Sauleda J, Nunez B, Castillo D, Aburto M, Portillo K, Balcells E, Badenes D, Valenzuela C, Fernandez E, Gonzalez T, Cano E, Acosta O, Leiro V, Romero A, Planas L, Villar A, Moreno A, Laporta R, Vicens V, Shull J, Franquet T, Luburich P, Molina M. Different Faces of Idiopathic Pulmonary Fibrosis With Preserved Forced Vital Capacity. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(2). DOI:10.1016/j.arbres.2021.03.018. PMID:33895005. IF:8 (Q1/2D). Document type: Article.
Betancor D, Olaguibel JM, Rodrigo JM, Arismendi E, Barranco P, Barroso B, Bobolea I, Cardaba B, Cruz MJ, Curto E, Del Pozo V, Gonzalez FJ, Martinez C, Mullol J, Munoz X, Picado C, Plaza V, Quirce S, Rial MJ, Soto L, Valero A, Valverde M, Sastre J. How reliably can algorithms identify eosinophilic asthma phenotypes using non-invasive biomarkers?. Clinical and Translational Allergy. 2022; 12(8):e12182. DOI:10.1002/clt2.12182. PMID:36000018. IF:4,4 (Q2/5D). Document type: Article.
Carrillo DD, Martinez MA, Barreiro E, Huguet ET, Sola RC, Garcia MM, Jimenez NC, Pons LR, Acuna CC, Hermosa JLR, Golpe R, Quintas RD, Sanchez S, Arroyo IT, Aparicio MB, Pacheco VA, Miravitlles M. Effectiveness and Safety of Inhaled Antibiotics in Patients With Chronic Obstructive Pulmonary Disease. A Multicentre Observational Study. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(1). DOI:10.1016/j.arbres.2021.03.009. PMID:33849721. IF:8 (Q1/2D). Document type: Article.
Castellvi I, Castillo D, Corominas H, Mariscal A, Orozco S, Benito N, Pomar V, Baucells A, Mur I, de la Rosa D, Lobo D, Millan AM, de Sosa NH, Filella D, Matas L, Martinez L, Juarez C, Casademont J, Domingo P. Krebs von den Lungen-6 glycoprotein circulating levels are not useful as prognostic marker in COVID-19 pneumonia: A large prospective cohort study. Frontiers in Medicine. 2022; 9:973918. DOI:10.3389/fmed.2022.973918. PMID:36004366. IF:3,9 (Q2/4D). Document type: Article.
Cendon L, Rafecas A, De La Rosa D, Castellví I, Spagnolo P, Castillo D. Systematic Review of Systemic Corticosteroids for Treatment of Organizing Pneumonia. Open Respiratory Archives. 2022; 4(4):100211. DOI:10.1016/j.opresp.2022.100211. Document type: Article.
Chiner E, Cordovilla R, de la Rosa D, Garcia M, Izquierdo JL, Otero R, Perez L, Sellares J, de Granda JI. Short and Long-Term Impact of COVID-19 Infection on Previous Respiratory Diseases. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58. DOI:10.1016/j.arbres.2022.03.011. PMID:35501222. IF:8 (Q1/2D). Document type: Review.
Clemente MG, Olveira C, Giron R, Maiz L, Sibila O, Golpe R, Menendez R, Rodriguez J, Barreiro E, Hermosa JLR, Prados C, de la Rosa D, Carbajal CM, Solis M, Martinez MA. Impact of Chronic Bronchial Infection by Staphylococcus aureus on Bronchiectasis. Journal of Clinical Medicine. 2022; 11(14):3960. DOI:10.3390/jcm11143960. PMID:35887723. IF:3,9 (Q2/4D). Document type: Article.
Company G, Nescolarde L, Pajares V, Torrego A, Riu PJ, Rosell J, Bragos R. Effect of Calibration for Tissue Differentiation Between Healthy and Neoplasm Lung Using Minimally Invasive Electrical Impedance Spectroscopy. IEEE Access. 2022; 10. DOI:10.1109/ACCESS.2022.3209809. IF:3,9 (Q2/4D). Document type: Article.
Company G, Nescolarde L, Pajares V, Torrego A, Riu PJ, Rosell J, Bragos R. Minimally Invasive Lung Tissue Differentiation Using Electrical Impedance Spectroscopy: A Comparison of the 3-and 4-Electrode Methods. IEEE Access. 2022; 10. DOI:10.1109/ACCESS.2021.3139223. IF:3,9 (Q2/4D). Document type: Article.
Conticini E, d’Alessandro M, Bergantini L, Castillo D, Cameli P, Frediani B, Cantarini L, Bargagli E. KL-6 in ANCA-Associated Vasculitis Patients with and without ILD: A Machine Learning Approach. Biology-Basel. 2022; 11(1):94. DOI:10.3390/biology11010094. PMID:35053092. IF:4,2 (Q2/3D). Document type: Article.
Crespo Lessmann, Ástrid (2022). Capítulo 9. Esputo inducido. In: Manual de procedimientos en el diagnóstico y seguimiento del asma. SEPAR. Editorial Respira. ISBN: 978-84-124841-1-3. Document type: Book chapter.
Crespo Lessmann, Ástrid. proGEMA 5.2. SEPAR. Luzán. ISBN:978-84-19069-12-2. Depósito Legal: M-17967-2022. Document type: Book chapter.
Curto E, Mateus EF, Crespo A, Osuna R, Ujaldon C, Garcia A, Galvan P, Soto L, Ramos D, Plaza V. Identification of Two Eosinophil Subsets in Induced Sputum from Patients with Allergic Asthma According to CD15 and CD66b Expression. International Journal of Environmental Research and Public Health. 2022; 19(20):13400. DOI:10.3390/ijerph192013400. PMID:36293979. Document type: Article.
Curto E, Ojanguren Í, Blanco M, Crespo A, Plaza V, Cisneros C, Serrano J, el Grupo Y. How to Approach Non Eosinophilic Asthma? Results of a Survey Conducted by the SEPAR Emerging Asthma Group. Open Respiratory Archives. 2022; 4(1):100149. DOI:10.1016/j.opresp.2021.100149. Document type: Article.
De la Rosa D (2022). Aspectos farmacoeconómicos de los antibióticos inhalados. In: Antibióticos inhalados. Editorial Neumología y Salud. ISBN: 978-84-945694-5-6. Document type: Book chapter.
De la Rosa D, Castillo D, Gutiérrez F (2022). Seguimiento del paciente post-COVID. In: Barreiro E. Fisiopatología de la COVID-19 en diferentes órganos y sistemas. Editorial Elsevier. ISBN: 978-84-1382-160-3. Document type: Book chapter.
de la Rosa D, GARCIA MM. Bronchiectasis exacerbations: certainties and future challenges. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE. 2022; 26(7). DOI:10.5588/ijtld.22.0185. PMID:35768930. IF:4 (Q2/5D). Document type: Editorial material.
de la Rosa D, Suárez G, Golpe R, Martinez MA, Carro LM. Inhaled Colistimethate Sodium in the Management of Patients with Bronchiectasis Infected by Pseudomonas aeruginosa: A Narrative Review of Current Evidence. Infection and Drug Resistance. 2022; 15. DOI:10.2147/IDR.S318173. IF:3,9 (Q2/4D). Document type: Review.
De Llano LP, Rivas DD, Malanda NM, Moral VP, Blanco J, Munoz M, Garcia I, Campos RMD, Martinez E, Mena AH, Cosio BG, Galo AP, Serrano CC. The Response to Biologics is Better in Patients with Severe Asthma Than in Patients with Asthma-COPD Overlap Syndrome. Journal of Asthma and Allergy. 2022; 15. DOI:10.2147/JAA.S338467. PMID:35330786. IF:3,2 (Q3/6D). Document type: Article.
Domínguez J, Plaza V, Li VW, Fonseca E, Cea L, Martin A, Sánchez M, Brady JE, Schelfhout J. Prevalence of chronic cough and patient characteristics in adults in Spain: A population-based cross-sectional survey. Chronic Respiratory Disease. 2022; 19:14799731221098722. DOI:10.1177/14799731221098722. PMID:35620851. IF:4,1 (Q2/4D). Document type: Article.
Franquet T, Franks TJ, Lee KS, Marchiori E, Mazzini S, Gimenez A, Johkoh T, Cho JH, Galvin JR. Human Oncoviruses and Thoracic Tumors: Understanding the Imaging Findings. 2022; 42(3). DOI:10.1148/rg.210157. PMID:35363552. IF:5,5 (Q1/2D). Document type: Article.
Franquet T, Gimenez A, Ketai L, Mazzini S, Rial A, Pomar V, Domingo P. Air trapping in COVID-19 patients following hospital discharge: retrospective evaluation with paired inspiratory/expiratory thin-section CT. EUROPEAN RADIOLOGY. 2022; 32(7). DOI:10.1007/s00330-022-08580-2. PMID:35226158. IF:5,9 (Q1/2D). Document type: Article.
Franquet T, Palleiro AG. Idiopathic pleuroparenchymal fibroelastosis. 2022; 64. DOI:10.1016/j.rx.7027.10.004. PMID:36737168. Document type: Article.
Garcia F, Alcazar B, Castillo D, Cilloniz C, Garcia A, Leiro V, Lojo I, Padilla A, Quezada CA, Rodriguez JA, Sanchez M, Sibila O, Martinez MA. Biological Biomarkers in Respiratory Diseases. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(4). DOI:10.1016/j.arbres.2022.01.010. PMID:35312522. IF:8 (Q1/2D). Document type: Article.
Gimenez A, Mazzini S, Franquet T. Radiological reports for interstitial lung disease. Radiologia. 2022; 64. DOI:10.1016/j.rx.2022.01.007. Document type: Article.
Gimenez AG, Mazzini SP, Franquet YT. Basic hrct patterns in diffuse interstitial lung disease. Radiologia. 2022; 64. DOI:10.1016/j.rx.2022.10.003. PMID:36737161. Document type: Article.
Gimenez S, Farre A, Morente F, Videla L, Gutierrez M, Clos S, Fernandez A, Blanco M, Altuna M, Pegueroles J, Asensio A, Benejam B, Batista M, Barroeta I, Fortuna A, Fortea J, Mayos M. Feasibility and Long-Term Compliance to Continuous Positive Airway Pressure Treatment in Adults With Down Syndrome, a Genetic Form of Alzheimer’s Disease. Frontiers in Neuroscience. 2022; 16:838412. DOI:10.3389/fnins.2022.838412. PMID:35431793. IF:4,3 (Q2/4D). Document type: Article.
Gonzalez J, Carmona P, Gracia E, Benitez ID, Anton A, Balana A, Diaz SB, Bernadich O, Cordoba A, Embid C, Espallargues M, Lujan M, Marti S, Castillo M, Tarrega J, Barbe F, Escarrabill J. Cluster Analysis of Home Mechanical Ventilation in COPD Patients: A Picture of the Real World and Its Impact on Mortality. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(9). DOI:10.1016/j.arbres.2021.12.015. PMID:35312537. IF:8 (Q1/2D). Document type: Article.
Herrera E, Ortega VE, Ampleford EJ, Sio YY, Granell R, de Roos E, Terzikhan N, Vergara EE, Hernandez N, Perez J, Martin E, Lorenzo F, Hashimoto S, Brinkman P, Jorgensen AL, Yan Q, Forno E, Vijverberg SJ, Lethem R, Espuela A, Gorenjak M, Eng C, Gonzalez R, Hernandez JM, Poza P, Sardon O, Corcuera P, Hawkins GA, Marsico A, Bahmer T, Rabe KF, Hansen G, Kopp MV, et al. [Plaza V]. Multi-ancestry genome-wide association study of asthma exacerbations. PEDIATRIC ALLERGY AND IMMUNOLOGY. 2022; 33(6):e13802. DOI:10.1111/pai.13802. PMID:35754128. IF:4,4 (Q1/1D). Document type: Article.
Martinez BC, Palleiro AG, Florindez SPM. CYSTIC LUNG DISEASE. Radiologia. 2022; 64. DOI:10.1016/j.rx.7027.09.008. PMID:36737165. Document type: Article.
Martinez MA, Faner R, Oscullo G, la Rosa D, Soler JJ, Ballester M, Muriel A, Agusti A. Chronic Bronchial Infection Is Associated with More Rapid Lung Function Decline in Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society. 2022; 19(11). DOI:10.1513/AnnalsATS.202108-974OC. PMID:35666811. IF:8,3 (Q1/2D). Document type: Article.
Martinez MA, Olveira C, Giron R, Garcia M, Maiz L, Sibila O, Golpe R, Mendez R, Hermosa JLR, Barreiro E, Prados C, Lopez JR, de la Rosa D. Peripheral Neutrophil-to-Lymphocyte Ratio in Bronchiectasis: A Marker of Disease Severity. 2022; 12(10):1399. DOI:10.3390/biom12101399. PMID:36291608. IF:5,5 (Q1/3D). Document type: Article.
Martinez MA, Oscullo G, Ponce S, Pastor E, Orosa B, Catalán P, Martinez A, Hernandez L, Muriel A, Chiner E, Vigil L, Carmona C, Mayos M, Garcia A, Gomez JD, Beauperthuy T, Bekki A, Gozal D. Effect of continuous positive airway pressure in very elderly with moderate-to-severe obstructive sleep apnea pooled results from two multicenter randomized controlled trials. SLEEP MEDICINE. 2022; 89. DOI:10.1016/j.sleep.2021.11.009. PMID:34915264. IF:4,8 (Q1/3D). Document type: Article.
Mediano O, Mangado NG, Montserrat JM, Alonso ML, Almendros I, Alonso A, Barbe F, Borsini E, Caballero C, Cano I, Villafranca FD, Carmona C, Alduenda JLC, Chiner E, Guevara J, de Manuel L, Duran J, Farre R, Franceschini C, Gaig C, Ramos PG, Garcia F, Garmendia O, Garcia TG, Pondal SG, Rodrigo MBH, Lecube A, Madrid JA, Lozano LM, Carrasco JLM, Masa JF, et al. [Mayos M, Rigau D]. International Consensus Document on Obstructive Sleep Apnea. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(1). DOI:10.1016/j.arbres.2021.03.017. PMID:33875282. IF:8 (Q1/2D). Document type: Article.
Mediano O, Mangado NG, Montserrat JM, Alonso ML, Almendros I, Alonso A, Barbe F, Borsini E, Caballero C, Cano I, Villafranca FD, Carmona C, Alduenda JLC, Chiner E, Guevara J, de Manuel L, Duran J, Farre R, Franceschini C, Gaig C, Ramos PG, Garcia F, Garmendia O, Garcia TG, Pondal SG, Rodrigo MBH, Lecube A, Madrid JA, Lozano LM, Carrasco JLM, Masa JF, et al. [Mayos M, Rigau D]. International consensus document on obstructive sleep apnea. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(1). DOI:10.1016/j.arbres.2021.03.027. PMID:35245183. IF:8 (Q1/2D). Document type: Article.
Molina M, Buendia I, Castillo D, Caro F, Valenzuela C, Selman M. Diagnostic and Therapeutic Developments in Progressive Pulmonary Fibrosis. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(5). DOI:10.1016/j.arbres.2021.12.017. PMID:35312511. IF:8 (Q1/2D). Document type: Article.
Mulet M, Osuna R, Zamora C, Porcel JM, Nieto JC, Perea L, Pajares V, Munoz AM, Calvo N, Sorolla MA, Vidal S. Influence of Malignant Pleural Fluid from Lung Adenocarcinoma Patients on Neutrophil Response. Cancers. 2022; 14(10):2529. DOI:10.3390/cancers14102529. PMID:35626131. IF:5,2 (Q2/3D). Document type: Article.
Oliveira LFD, Mallafré C, Giner J, Perea L, Sibila O, Pardo A, Marco S. Breath analysis using electronic nose and gas chromatography-mass spectrometry: A pilot study on bronchial infections in bronchiectasis. CLINICA CHIMICA ACTA. 2022; 526. DOI:10.1016/j.cca.2021.12.019. IF:5 (Q1/2D). Document type: Article.
Palones E, Pajares V, Lopez L, Castillo D, Torrego A. Sarcoidosis following SARS-CoV-2 infection: Cause or consequence?. Respirology Case Reports. 2022; 10(6):e0955. DOI:10.1002/rcr2.955. PMID:35505665. Document type: Article.
Paredes AM, Alvarez JM, Perez N, Puy C, Penacoba P, Segura M, Anton A. Controlled cycles in spontaneous-timed noninvasive ventilation: Incidence and associated factors. RESPIRATORY MEDICINE. 2022; 204:107005. DOI:10.1016/j.rmed.2022.107005. PMID:36270154. IF:4,3 (Q2/4D). Document type: Article.
Paris JM, Sanchez CA, Blanco M, Dominguez J, Donaire JG, Marcos NS, Plaza V. Current expert opinion and attitudes to optimize telemedicine and achieve control in patients with asthma in post-pandemic era: The COMETA consensus. Atencion Primaria. 2022; 54(12):102492. DOI:10.1016/j.aprim.2022.102492. PMID:36272223. IF:2,5 (Q3/6D). Document type: Article.
Peñacoba P, Fortuna AM, Mayos M. Management of obstructive sleep apnea in primary care in relation to the new international consensus document. Open Respiratory Archives. 2022; 4(1):100150. DOI:10.1016/j.opresp.2021.100150. Document type: Editorial material.
Peñacoba P, Llauger MA, Fortuna AM, Flor X, Sampol G, Pedro AM, Grau N, Santiveri C, Juvanteny J, Aoiz JI, Bayó J, Lloberes P, Mayos M, Domínguez L, Valverde P, Santos MªÁ, Farga MªM, Reverté M, Argemí N, Medrano C, Puig M, the PASHOS Working G. A new tool to screen patients with severe obstructive sleep apnea in the primary care setting: a prospective multicenter study. BMC Pulmonary Medicine. 2022; 22(1):38. DOI:10.1186/s12890-022-01827-0. PMID:35033055. IF:3,1 (Q3/7D). Document type: Article.
Perrot JC, Segura M, Beranuy M, Gich I, Nadal MJ, Pintor A, Terra J, Ramirez E, Paz LD, Bascuñana H, Plaza V, Güell R. Comparison of post-COVID symptoms in patients with different severity profiles of the acute disease visited at a rehabilitation unit. PLoS One. 2022; 17:e0274520. DOI:10.1371/journal.pone.0274520. PMID:36112577. IF:3,7 (Q2/4D). Document type: Article.
Plaza V, Alobid I, Alvarez C, Blanco M, Ferreira J, Garcia G, Gomez A, Gomez F, Hidalgo A, Korta J, Molina J, Pellegrini FJ, Perez M, Plaza J, Praena M, Quirce S, Sanz J. Spanish Asthma Management Guidelines (GEMA) VERSION 5.1. Highlights and Controversies. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(2). DOI:10.1016/j.arbres.2021.05.010. PMID:34167859. IF:8 (Q1/2D). Document type: Article.
Quint JK, Arnetorp S, Kocks JWH, Kupczyk M, Nuevo J, Plaza V, Cabrera C, Raherison C, Walker B, Penz E, Gilbert I, Lugogo NL, van der Valk RJP, Fong A, Qian C, Fabry C, Touboul C, Brzostek D, Maslova E, Surmont F, Goike H, Gandhi H, Korevaar JC, Tkacz J, Johnston K, Peres da Costa K, van L, Vervloet M, Pollack M, Hernandez P, Boarino S, Noorduyn SG, Beekman W, Weesie YM, SABINA North American and European Study C. Short-Acting Beta-2-Agonist Exposure and Severe Asthma Exacerbations: SABINA Findings From Europe and North America. Journal of Allergy and Clinical Immunology-In Practice. 2022; 10(9). DOI:10.1016/j.jaip.2022.02.047. PMID:35364341. IF:9,4 (Q1/1D). Document type: Article.
Rivera CM, Crespo A, Arismendi E, Munoz M, Aguilar X, Ausin P, Bobolea I, Duch GD, Teixido RP, Talaverano GS, Sabardia AS, Gall XM. Challenges for asthma units in response to COVID-19: a qualitative group dynamics analysis. JOURNAL OF ASTHMA. 2022; 59(6). DOI:10.1080/02770903.2021.1917605. PMID:33882776. IF:1,9 (Q4/8D). Document type: Article.
Rodrigo A, Alonso A, Barril S, Farinas O, Gueell E, Pascual A, Castillo D. Impact of Early Referral to Palliative Care in Patients with Interstitial Lung Disease. JOURNAL OF PALLIATIVE MEDICINE. 2022; 25(9). DOI:10.1089/jpm.2021.0458. PMID:35714348. IF:2,8 (Q3/6D). Document type: Article.
Rodrigo A, Giner J, Perea L, Merino JL, Albacar N, Solarat B, Castillo D, Faner R, Agusti A, Sibila O. Predicting Early Hospital Readmissions in COPD Patients Using an Electronic Nose. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(9). DOI:10.1016/j.arbres.2022.01.015. PMID:35312493. IF:8 (Q1/2D). Document type: Letter.
Romano A, Ruiz I, de la Rosa D, Peñacoba P. Tapia’s syndrome and pronation in a patient with pneumonia due to COVID-19: About a case. ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA. 2022; 40(9). DOI:10.1016/j.eimc.2021.06.019. PMID:35729048. IF:2,5 (Q4/8D). Document type: Letter.
Romero JD, Blanco M, Serrano CC, Diaz D, Piqueres RF, Lopez V, Merino V, Soto L, Dominguez J. Support for Home Administration of Biological Therapy in Patients With Severe Asthma: BioCart (c). JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2022; 32(6). DOI:10.18176/jiaci.0786. PMID:35088761. IF:7,2 (Q1/2D). Document type: Article.
Sanchez M, Gracia E, Benitez ID, Zapater A, Torres G, Sanchez A, Aldoma A, de Batlle J, Targa A, Abad J, Duran J, Urrutia A, Mediano O, Masdeu MJ, Ordax E, Masa JF, De la Pena M, Mayos M, Coloma R, Montserrat JM, Chiner E, Minguez O, Pascual L, Cortijo A, Martinez D, Dalmases M, Lee CH, McEvoy RD, Barbe F, Spanish N. Long-Term Effect of Obstructive Sleep Apnea and Continuous Positive Airway Pressure Treatment on Blood Pressure in Patients with Acute Coronary Syndrome A Clinical Trial. Annals of the American Thoracic Society. 2022; 19(10). DOI:10.1513/AnnalsATS.202203-260OC. PMID:35442180. IF:8,3 (Q1/2D). Document type: Article.
Sapina E, Benitez ID, Torres G, Fortuna AM, Marquez PP, Masa JF, Drager LF, Cabrini M, Felez M, Vazquez S, Abad J, Lee C, Garcia F, Casitas R, Mediano O, Peralta SR, Martinez D, Sanchez M, Barbe F, Dalmases M. Effect of CPAP treatment on BP in resistant hypertensive patients according to the BP dipping pattern and the presence of nocturnal hypertension. HYPERTENSION RESEARCH. 2022; 45(3). DOI:10.1038/s41440-021-00762-7. PMID:34952953. IF:5,4 (Q2/3D). Document type: Article.
Serra C, Torrego A, Pajares V, Millan P, Barril S, Alonso A, Navarro M, Lopez L, Franquet T, Castillo D. Bronchoalveolar lavage complements transbronchial cryobiopsy diagnosis in diffuse interstitial lung diseases. Journal Of Bronchology And Interventional Pulmonology. 2022; 29(1). DOI:10.1097/LBR.0000000000000770. PMID:33828048. Document type: Article.
Torrego A, Muñoz AM, Lucena CM, Castro P, López L, Badía JR, Betbesé A, Ramirez J, Andreo F, Fernández M-T, Fabra M, Pajares V, Agustí C. Safety and Feasibility of Transbronchial Cryobiopsy in Mechanically Ventilated Patients. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(8). DOI:10.1016/j.arbres.2021.11.005. PMID:35312520. IF:8 (Q1/2D). Document type: Letter.
Torrego A, Pajares V, Maldonado F, Hetzel J. Transbronchial Cryobiopsy Bohemian Rhapsody. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(8). DOI:10.1016/j.arbres.2021.08.004. PMID:35312593. IF:8 (Q1/2D). Document type: Editorial material.
Villar F, de la Rosa D, Fariñas F, Jiménez CA. Immunosenescence, Immune Fitness and Vaccination Schedule in the Adult Respiratory Patient. Open Respiratory Archives. 2022; 4(3):100181. DOI:10.1016/j.opresp.2022.100181. Document type: Review.
Villegas DC, Barril S, Giner J, Millan P, Rodrigo A, Merino JL, Sibila O. Study of Diffuse Interstitial Lung Disease With the Analysis of Volatile Particles in Exhaled Air. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(1). DOI:10.1016/j.arbres.2021.03.014. PMID:33867204. IF:8 (Q1/2D). Document type: Letter.
Wang X, Villa C, Dobarganes Y, Olveira C, Girón R, García M, Máiz L, Sibila O, Golpe R, Menndez R, Rodríguez J, Prados C, Martinez MA, Rodriguez JL, De La Rosa D, Duran X, Garcia J, Barreiro E. Systemic Inflammatory Biomarkers Define Specific Clusters in Patients with Bronchiectasis: A Large-Cohort Study. 2022; 10(2):225. DOI:10.3390/biomedicines10020225. PMID:35203435. IF:4,7 (Q1/3D). Document type: Article.
Wang XJ, Olveira C, Giron R, Garcia M, Maiz L, Sibila O, Golpe R, Menendez R, Rodriguez J, Prados C, Martinez MA, Rodriguez JL, de la Rosa D, Qin LY, Duran X, Garcia J, Barreiro E. Blood Neutrophil Counts Define Specific Clusters of Bronchiectasis Patients: A Hint to Differential Clinical Phenotypes. 2022; 10(5):1044. DOI:10.3390/biomedicines10051044. PMID:35625780. IF:4,7 (Q1/3D). Document type: Article.
Zapater A, Solelhac G, Sánchez A, Gracia E, Benitez ID, Torres G, De Batlle J, Haba J, Berger M, Abad J, Duran J, Urrutia A, Mediano O, Masdeu MJ, Ordax E, Masa JF, De la Peña M, Mayos M, Coloma R, Montserrat JM, Chiner E, Mínguez O, Pascual L, Cortijo A, Martínez D, Dalmases M, Lee C-H, McEvoy RD, Barbé F, Heinzer R, Sánchez M, Spanish N. Respiratory Polygraphy Patterns and Risk of Recurrent Cardiovascular Events in Patients With Acute Coronary Syndrome. Frontiers in Medicine. 2022; 9:870906. DOI:10.3389/fmed.2022.870906. PMID:35833104. IF:3,9 (Q2/4D). Document type: Article.

Publicacions 2021

Alserawan L, Penacoba P, Echevarria S, Castillo D, Ortiz E, Martinez L, Naranjo EM, Domingo P, Castellvi I, Juarez C, Mariscal A. Growth Differentiation Factor 15 (GDF-15): A Novel Biomarker Associated with Poorer Respiratory Function in COVID-19. Diagnostics. 2021; 11(11):1998. DOI:10.3390/diagnostics11111998. PMID:34829345. IF:3,992.
Cano E, Rodriguez TV, Martin I, Villegas DC, Garcia JJ, de Miguel EB, Robles A, Galvan MF, Roibas CM, Lara SH, Bermudo G, Moyano MG, Portal J, Torres JS, Narvaez J, Molina M. Diagnostic delay of associated interstitial lung disease increases mortality in rheumatoid arthritis. Scientific Reports. 2021; 11(1):9184. DOI:10.1038/s41598-021-88734-2. PMID:33911185. IF:4,996.
Casado P, Vazquez L, Botana M, Andrade MA, Ferreiro L, Capilla ES, Nunez A, de Miguel EB, Pajares V, Fernandez A. A rapid calprotectin test for the diagnosis of pleural effusion. PLoS One. 2021; 16(6):e0252714. DOI:10.1371/journal.pone.0252714. PMID:34111153. IF:3,752.
Casanova C, Gonzalez E, Martinez C, Cosio BG, Fuster A, Feu N, Solanes I, Cabrera C, Marin JM, Balcells E, Peces G, de Torres JP, Marin M, Calle M, Golpe R, Ojeda E, Divo M, Pinto V, Amado C, Lopez JL, Celli BR. Natural Course of the Diffusing Capacity of the Lungs for Carbon Monoxide in COPD Importance of Sex. CHEST. 2021; 160(2). DOI:10.1016/j.chest.2021.03.069. PMID:33878339. IF:10,262.
Castillo D, Barril S, Rodrigo A, Millan P, Suarez G, Alonso A, Franquet T, Lopez L, Castellvi I, Plaza V, Sibila O. EARLY HOSPITAL READMISSION INCREASES SHORT AND LONG – TERM MORTALITY IN PATIENTS WITH INTERSTITIAL LUNG DISEASE. SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES. 2021; 38(2):e2021021. DOI:10.36141/svdld.v38i2.10709. PMID:34316260. IF:1,803.
Corominas H, Castellvi I, Diaz C, Matas L, de la Rosa D, Mangues MA, Moya P, Pomar V, Benito N, Moga E, Hernandez N, Casademont J, Domingo P. Sarilumab (IL-6R antagonist) in critically ill patients with cytokine release syndrome by SARS-CoV2. MEDICINE. 2021; 100(19):e25923. DOI:10.1097/MD.0000000000025923. PMID:34106658. IF:1,817.
Corominas H, Castellvi I, Pomar V, Antonijoan R, Mur I, Matas L, Gich I, de Benito N, Laiz A, Castillo D, Villamarin L, Filella D, Mill AM, Quijada MA, Puig M, Casademont J, Domingo P. Effectiveness and safety of intravenous tocilizumab to treat COVID-19-associated hyperinflammatory syndrome: Covizumab-6 observational cohort. CLINICAL IMMUNOLOGY. 2021; 223:108631. DOI:10.1016/j.clim.2020.108631. PMID:33189888. IF:10,190.
Crespo A, Bernal S, del Rio E, Rojas E, Martinez C, Marina N, Pallares A, Pascual S, Garcia JL, Padilla A, Curto E, Cisneros C, Serrano J, Baiget M, Plaza V. Association of the CFTR gene with asthma and airway mucus hypersecretion. PLoS One. 2021; 16(6):e0251881. DOI:10.1371/journal.pone.0251881. PMID:34086689. IF:3,752.
Crespo A, Plaza V. Multidisciplinary consensus on sputum induction biosafety during the COVID-19 pandemic. ALLERGY. 2021; 76(8). DOI:10.1111/all.14697. PMID:33314245. IF:14,710.
de Torres JP, O’Donnell DE, Marin JM, Cabrera C, Casanova C, Marin M, Ezponda A, Cosio BG, Martinez C, Solanes I, Fuster A, Neder JA, Gonzalez J, Celli BR. Clinical and Prognostic Impact of Low Diffusing Capacity for Carbon Monoxide Values in Patients With Global Initiative for Obstructive Lung Disease I COPD. CHEST. 2021; 160(3). DOI:10.1016/j.chest.2021.04.033. PMID:33901498. IF:10,262.
Fischer JB, Frisk LK, Scholkmann F, Delgado R, Mayos M, Durduran T. Cerebral and systemic physiological effects of wearing face masks in adults. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021; 118(41):e2109111118. DOI:10.1073/pnas.2109111118. PMID:34607955. IF:12,779.
Garcia A, de la Rosa D, Oscullo G, Castillo D, Lopez R, Martinez MA. Coagulation disorders and thromboembolic disease in COVID-19 review of current evidence in search of a better approach. Journal of Thoracic Disease. 2021; 13(2). DOI:10.21037/jtd-20-3062. PMID:33717596. IF:3,005.
Martinez MA, Faner R, Oscullo G, de la Rosa D, Soler JJ, Ballester M, Muriel A, Agusti A. Risk Factors and Relation with Mortality of a New Acquisition and Persistence of Pseudomonas aeruginosa in COPD Patients. COPD-Journal of Chronic Obstructive Pulmonary Disease. 2021; 18(3). DOI:10.1080/15412555.2021.1884214. PMID:33941014. IF:2,069.
Martinez MA, Faner R, Oscullo G, la Rosa D, Soler JJ, Ballester M, Muriel A, Agusti A. Chronic bronchial infection and incident cardiovascular events in chronic obstructive pulmonary disease patients: A long-term observational study. RESPIROLOGY. 2021; 26(8). DOI:10.1111/resp.14086. PMID:34002922. IF:6,175.
Martinez MA, Villa C, Dobarganes Y, Giron R, Maiz L, Garcia M, Sibila O, Golpe R, Rodriguez J, Barreiro E, Rodriguez JL, Menendez R, Prados C, de la Rosa D, Olveira C. RIBRON: The spanish Online Bronchiectasis Registry. Characterization of the First 1912 Patients. ARCHIVOS DE BRONCONEUMOLOGIA. 2021; 57(1). DOI:10.1016/j.arbres.2019.12.021. PMID:32081438. IF:6,333.
Milagro J, Soto L, Giner J, Varon C, Laguna P, Bailon R, Plaza V, Gil E. Asthmatic subjects stratification using autonomic nervous system information. Biomedical Signal Processing and Control. 2021; 69:102802. DOI:10.1016/j.bspc.2021.102802. IF:5,076.
Millán P, Pajares V, Guerrero R, Villalba J, Torrego A. Recurrent Haemoptysis Secondary to Abnormal Arterial Supply to the Right Lower Lobe of the Lung. ARCHIVOS DE BRONCONEUMOLOGIA. 2021; 57(10). DOI:10.1016/j.arbres.2020.10.004. PMID:33223304. IF:6,333.
Navarro A, de la Rosa D, Esquinas C, Miravitlles M, Martinez MA, Almagro P. Evolution and Comparative Analysis of Hospitalizations in Spain Due to COPD and Bronchiectasis between 2004 and 2015. COPD-Journal of Chronic Obstructive Pulmonary Disease. 2021; 18(2). DOI:10.1080/15412555.2021.1896692. PMID:33729066. IF:2,069.
Perez de Llano LP, Davila I, Martinez E, Dominguez J, Almonacid C, Colas C, Garcia JL, Carmona L, de Yebenes MJG, Cosio BG, Torrego A, MENA AH. Development of a Tool to Measure the Clinical Response to Biologic Therapy in Uncontrolled Severe Asthma: The FEV1, Exacerbations, Oral Corticosteroids, Symptoms Score. Journal of Allergy and Clinical Immunology-In Practice. 2021; 9(7). DOI:10.1016/j.jaip.2021.01.033. PMID:33549843. IF:6,333.
Plaza V, Arnedillo A, Blanco M, Ignacio JM, Urrutia I. Consensus on the treatment of allergic asthma with sublingual house dust mite immunotherapy in the field of pneumology. Expert Review of Respiratory Medicine. 2021; 15(10). DOI:10.1080/17476348.2021.1942846. PMID:34128758. IF:4,300.
Plaza V, Giner J, Curto E, Alonso MB, Orue MI, Vega JM, Cosio BG. Assessing Adherence by Combining the Test of Adherence to Inhalers With Pharmacy Refill Records. JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2021; 31(1). DOI:10.18176/jiaci.0461. PMID:31599726. IF:8,185.
Posadas T, Oscullo G, Zaldivar E, Villa C, Dobarganes Y, Giron R, Olveira C, Maiz L, Garcia M, Sibila O, Golpe R, Rodriguez J, Barreiro E, Rodriguez JL, Menendez R, Prados C, de la Rosa D, Martinez MA. C-Reactive Protein Concentration in Steady-State Bronchiectasis: Prognostic Value of Future Severe Exacerbations. Data From the Spanish Registry of Bronchiectasis (RIBRON). ARCHIVOS DE BRONCONEUMOLOGIA. 2021; 57(1). DOI:10.1016/j.arbres.2019.12.017. PMID:32331706. IF:6,333.
Reyes D, Alonso J, Mayos M, Nunez C, Llauger J, Belmonte I, Pedrosa I, Segovia S, Diaz J. Correlation Between Respiratory Accessory Muscles and Diaphragm Pillars MRI and Pulmonary Function Test in Late-Onset Pompe Disease Patients. Frontiers in Neurology. 2021; 12:621257. DOI:10.3389/fneur.2021.621257. PMID:33732206. IF:4,086.
Rial MJ, Alvarez MJ, Arismendi E, Caballero ML, Canas JA, Cruz MJ, Gonzalez FJ, Luna JA, Martinez C, Mullol J, Munoz X, Olaguibel JM, Picado C, Plaza V, Quirce S, Romero C, Salgado FJ, Sastre B, Soto L, Valero A, Valverde M, Sastre J, del Pozo V. Clinical and inflammatory characteristics of patients with asthma in the Spanish MEGA project cohort. Clinical and Translational Allergy. 2021; 11(1):e12001. DOI:10.1002/clt2.12001. PMID:33900052. IF:5,657.
Rubio MC, Hermosa JLR, de Torres JP, Marin JM, Martinez C, Fuster A, Cosio BG, Peces G, Solanes I, Feu N, Lopez JL, Casanova C, CHAIN I. COPD Clinical Control: predictors and long-term follow-up of the CHAIN cohort. RESPIRATORY RESEARCH. 2021; 22(1):36. DOI:10.1186/s12931-021-01633-y. PMID:33541356. IF:7,162
Sebastiani M, Luppi F, Sambataro G, Villegas DC, Cerri S, Tomietto P, Cassone G, Bocchino M, Atienza B, Cameli P, Alvarado PM, Faverio P, Bargagli E, Vancheri C, Gonzalez MA, Clini E, Salvarani C, Manfredi A. Interstitial Lung Disease and Anti-Myeloperoxidase Antibodies: Not a Simple Association. Journal of Clinical Medicine. 2021; 10(12):2548. DOI:10.3390/jcm10122548. PMID:34207641. IF:4,964.
Shull JG, Pay MT, Lara Compte C, Olid M, Bermudo G, Portillo K, Sellarés J, Balcells E, Vicens-Zygmunt V, Planas-Cerezales L, Badenes-Bonet D, Blavia R, Rivera-Ortega P, Moreno A, Sans J, Perich D, Barril S, Esteban L, Garcia-Bellmunt L, Esplugas J, Suarez-Cuartin G, Bordas-Martinez J, Castillo D, Jolis R, Salvador I, Eizaguirre Anton S, Villar A, et al. Mapping IPF helps identify geographic regions at higher risk for disease development and potential triggers. Respirology. 2021;26(4):352-359. DOI:10.1111/resp.13973. PMID: 33167075. IF:6,175.
Tabar AI, Delgado J, Gonzalez E, Arroabarren E, Retes LS, Dominguez J. Recent Advances in Allergen-Specific Immunotherapy as Treatment for Allergic Asthma: A Practical Overview. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2021; 182(6). DOI:10.1159/000513811. PMID:33631755. IF:3,767.
Torrego A, Herth FJ, Munoz AM, Puente L, Facciolongo N, Bicknell S, Novali M, Gasparini S, Bonifazi M, Dheda K, Andreo F, Votruba P, Langton D, Flandes J, Fielding D, Bonta PI, Skowasch D, Schulz C, Darwiche K, McMullen E, Grubb GM, Niven R. Bronchial Thermoplasty Global Registry (BTGR): 2-year results. BMJ Open. 2021; 11(12):e053854. DOI:10.1136/bmjopen-2021-053854. PMID:34916324. IF:3,006.
Valero AL, Trigueros JA, Plaza V. Multidisciplinary consensus on inhaled therapy in asthma. Expert Review of Respiratory Medicine. 2021;15(3):425-434. DOI:10.1080/17476348.2021.1841639. PMID: 33170733. IF:4,300.
Villegas DC, Barril S, Giner J, Millan P, Rodrigo A, Merino JL, Sibila O. Study of diffuse interstitial lung disease with the analysis of volatile particles in exhaled air. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(1). DOI:10.1016/j.arbres.2021.03.023. IF:1,803.
Wang XJ, Villa C, Dobarganes Y, Olveira C, Giron R, Garcia M, Maiz L, Sibila O, Golpe R, Menendez R, Rodriguez J, Prados C, Martinez MA, Rodriguez JL, de la Rosa D, Duran X, Barreiro E. Differences in Nutritional Status and Inflammatory Biomarkers between Female and Male Patients with Bronchiectasis: A Large-Cohort Study. Biomedicines. 2021; 9(8):905. DOI:10.3390/biomedicines9080905. PMID:34440109. IF:4,757.
Wang XJ, Villa C, Dobarganes Y, Olveira C, Giron R, Garcia M, Maiz L, Sibila O, Golpe R, Menendez R, Rodriguez J, Prados C, Martinez MA, Rodriguez JL, de la Rosa D, Duran X, Garcia J, Barreiro E. Phenotypic Clustering in Non-Cystic Fibrosis Bronchiectasis Patients: The Role of Eosinophils in Disease Severity. International Journal of Environmental Research and Public Health. 2021; 18(16):8431. DOI:10.3390/ijerph18168431. PMID:34444179. IF:4,614.

L’INSTITUT DE RECERCA DE L’HOSPITAL DE LA SANTA CREU I SANT PAU participa en el projecte DESENVOLUPAMENT CLÍNIC I VALIDACIÓ DE BIOMARCADORS D’UN NOU TRACTAMENT ORAL PER L’ASMA A TRAVÉS D’UN ASSAIG DE FASE II, expedient RTC-2016-4698-1 desenvolupat en col·laboració amb l’entitat: PALOBIOFARMA S.L., que està sent cofinançat per:

El Ministerio de Economía y Competitividad, dins el Programa Estatal d’Investigació, Desenvolupament i Innovació Orientada als Reptes de la Societat, en el marc del Pla Estatal d’Investigació Científica i Tècnica i d’Innovació 2013-2016.
La Unió Europea, a càrrec del fons FEDER, amb l’objectiu de “Promoure el desenvolupament tecnològic, la innovació i una investigació de qualitat”.

mineco feder

presentació

Principals línies de recerca

Asma

Exacerbacions d’asma.
Asma sever.
Guies de bones pràctiques clíniques per asma.
Inflamació bronquial.
Asma experimental i mecanismes patogènics.
Biobancs multicèntrics especialitzats en biòpsies bronquials per la recerca en asma.
Termoplàstia bronquial.
Assajos clínics.

Malaltia pulmonar obstructiva crònica (MPOC) i la insuficiència respiratòria

Respiració mecànica no invasiva.
Rehabilitació respiratòria.
Patofisiologia.
Exacerbació.

Síndrome d’Apnea-Hipopnea del Son (SAHOS)

Fisiologia i conseqüències terapèutiques clíniques de SAHOS.
Síndrome de la hipoventilació per obesitat.
Inflamació de les vies respiratòries i SAHOS.

Reptes

Consolidar una unitat de lideratge en assajos clínics per malalties respiratòries.
Captació de contractes amb la indústria farmacèutica i biotecnològica per desenvolupament preclínic, utilitzant les capacitats del nostre laboratori de recerca bàsica i els models animals experimentals.
Reclutament de personal investigador en formació per la realització de doctorat.
Suport al desenvolupament de xarxes de recerca multidisciplinàries com la Xarxa Respiratòria de Barcelona i el Programa Integrat de Recerca en Asma de la Societat Espanyola de Pneumologia i Cirurgia Toràcica (SEPAR) i col·laboració o involucració del grup en xarxes ja existents, com CIBER-ES (malalties respiratòries).

2017 Scientific Report – Chronic

equip

Coordinació del grup

PLAZA MORAL, VICENTE FGS
vplaza@santpau.cat

Co-coordinador:

Ramos Barbon, David FGS
dramosb@santpau.cat

Membres

producció científica

Publicacions 2022

(JIF 2022)

Agusti A, De Stefano G, Levi A, Munoz X, Romero C, Sibila O, Lopez A, Moral VP, Curto E, Echazarreta AL, Marquez SE, Pascual S, Santos S, Marin A, Valdes L, Saldarini F, Salgado C, Casanovas G, Varea S, Rios J, Faner R. Add-on inhaled budesonide in the treatment of hospitalised patients with COVID-19: a randomised clinical trial. EUROPEAN RESPIRATORY JOURNAL. 2022; 59(3):2103036. DOI:10.1183/13993003.03036-2021. PMID:35144989. IF:24,3 (Q1/1D). Document type: Letter.
Alfonsi C, Stephan C, Cortes E, Palacios NJ, Podzamczer I, Cruz NG, Jimenez MRD, Mico SI, Vila MT, Jeltsch K, Hubschmann OK, Opladen T, Fragua RV, Gomez T, Fortuny OA, Jimenez IG, Laso EL, Martinez AR, Lopez JM, Garcia A. Volumetric study of brain MRI in a cohort of patients with neurotransmitter disorders. NEURORADIOLOGY. 2022; 64(11). DOI:10.1007/s00234-022-02989-8. PMID:35662359. IF:2,8 (Q2/5D). Document type: Article.
Alvarez FJ, Blanco M, Casas F, Plaza V, González FJ, Carretero JÁ, Castilla M, Cisneros C, Diaz D, Domingo C, Martínez E, Muñoz X, Padilla A, Perpiñá M, Soto G. Consensus document for severe asthma in adults. 2022 update. Open Respiratory Archives. 2022; 4(3):100192. DOI:10.1016/j.opresp.2022.100192. Document type: Article.
Badenes D, Rodo A, Castillo D, Vicens V, Bermudo G, Hernandez F, Portillo K, Martinez J, Chalela R, Caguana O, Sellares J, Molina M, Duran X, Gea J, Rodriguez DA, Balcells E. Predictors and changes of physical activity in idiopathic pulmonary fibrosis. BMC Pulmonary Medicine. 2022; 22(1):340. DOI:10.1186/s12890-022-02134-4. PMID:36085057. IF:3,1 (Q3/7D). Document type: Article.
Baptista L, Rodrigo JM, Mínguez P, Valverde M, Arismendi E, Barranco P, Barroso B, Bobolea I, Cañas JA, Cárdaba B, Cruz MJ, Curto E, Domínguez J, García R, González FJ, Martínez C, Mullol J, Muñoz X, Olaguibel JM, Picado C, Plaza V, Quirce S, Rial MJ, Sastre B, Soto L, Valero A, del Pozo V, Sastre J. Anxiety and body mass index affect asthma control: data from a prospective Spanish cohort. Journal of Allergy and Clinical Immunology-In Practice. 2022; 10(3). DOI:10.1016/j.jaip.2021.10.013. PMID:34673289. IF:9,4 (Q1/1D). Document type: Letter.
Bermudo G, Suarez G, Rivera P, Rodriguez JA, Sauleda J, Nunez B, Castillo D, Aburto M, Portillo K, Balcells E, Badenes D, Valenzuela C, Fernandez E, Gonzalez T, Cano E, Acosta O, Leiro V, Romero A, Planas L, Villar A, Moreno A, Laporta R, Vicens V, Shull J, Franquet T, Luburich P, Molina M. Different Faces of Idiopathic Pulmonary Fibrosis With Preserved Forced Vital Capacity. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(2). DOI:10.1016/j.arbres.2021.03.018. PMID:33895005. IF:8 (Q1/2D). Document type: Article.
Betancor D, Olaguibel JM, Rodrigo JM, Arismendi E, Barranco P, Barroso B, Bobolea I, Cardaba B, Cruz MJ, Curto E, Del Pozo V, Gonzalez FJ, Martinez C, Mullol J, Munoz X, Picado C, Plaza V, Quirce S, Rial MJ, Soto L, Valero A, Valverde M, Sastre J. How reliably can algorithms identify eosinophilic asthma phenotypes using non-invasive biomarkers?. Clinical and Translational Allergy. 2022; 12(8):e12182. DOI:10.1002/clt2.12182. PMID:36000018. IF:4,4 (Q2/5D). Document type: Article.
Carrillo DD, Martinez MA, Barreiro E, Huguet ET, Sola RC, Garcia MM, Jimenez NC, Pons LR, Acuna CC, Hermosa JLR, Golpe R, Quintas RD, Sanchez S, Arroyo IT, Aparicio MB, Pacheco VA, Miravitlles M. Effectiveness and Safety of Inhaled Antibiotics in Patients With Chronic Obstructive Pulmonary Disease. A Multicentre Observational Study. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(1). DOI:10.1016/j.arbres.2021.03.009. PMID:33849721. IF:8 (Q1/2D). Document type: Article.
Castellvi I, Castillo D, Corominas H, Mariscal A, Orozco S, Benito N, Pomar V, Baucells A, Mur I, de la Rosa D, Lobo D, Millan AM, de Sosa NH, Filella D, Matas L, Martinez L, Juarez C, Casademont J, Domingo P. Krebs von den Lungen-6 glycoprotein circulating levels are not useful as prognostic marker in COVID-19 pneumonia: A large prospective cohort study. Frontiers in Medicine. 2022; 9:973918. DOI:10.3389/fmed.2022.973918. PMID:36004366. IF:3,9 (Q2/4D). Document type: Article.
Cendon L, Rafecas A, De La Rosa D, Castellví I, Spagnolo P, Castillo D. Systematic Review of Systemic Corticosteroids for Treatment of Organizing Pneumonia. Open Respiratory Archives. 2022; 4(4):100211. DOI:10.1016/j.opresp.2022.100211. Document type: Article.
Chiner E, Cordovilla R, de la Rosa D, Garcia M, Izquierdo JL, Otero R, Perez L, Sellares J, de Granda JI. Short and Long-Term Impact of COVID-19 Infection on Previous Respiratory Diseases. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58. DOI:10.1016/j.arbres.2022.03.011. PMID:35501222. IF:8 (Q1/2D). Document type: Review.
Clemente MG, Olveira C, Giron R, Maiz L, Sibila O, Golpe R, Menendez R, Rodriguez J, Barreiro E, Hermosa JLR, Prados C, de la Rosa D, Carbajal CM, Solis M, Martinez MA. Impact of Chronic Bronchial Infection by Staphylococcus aureus on Bronchiectasis. Journal of Clinical Medicine. 2022; 11(14):3960. DOI:10.3390/jcm11143960. PMID:35887723. IF:3,9 (Q2/4D). Document type: Article.
Company G, Nescolarde L, Pajares V, Torrego A, Riu PJ, Rosell J, Bragos R. Effect of Calibration for Tissue Differentiation Between Healthy and Neoplasm Lung Using Minimally Invasive Electrical Impedance Spectroscopy. IEEE Access. 2022; 10. DOI:10.1109/ACCESS.2022.3209809. IF:3,9 (Q2/4D). Document type: Article.
Company G, Nescolarde L, Pajares V, Torrego A, Riu PJ, Rosell J, Bragos R. Minimally Invasive Lung Tissue Differentiation Using Electrical Impedance Spectroscopy: A Comparison of the 3-and 4-Electrode Methods. IEEE Access. 2022; 10. DOI:10.1109/ACCESS.2021.3139223. IF:3,9 (Q2/4D). Document type: Article.
Conticini E, d’Alessandro M, Bergantini L, Castillo D, Cameli P, Frediani B, Cantarini L, Bargagli E. KL-6 in ANCA-Associated Vasculitis Patients with and without ILD: A Machine Learning Approach. Biology-Basel. 2022; 11(1):94. DOI:10.3390/biology11010094. PMID:35053092. IF:4,2 (Q2/3D). Document type: Article.
Crespo Lessmann, Ástrid (2022). Capítulo 9. Esputo inducido. In: Manual de procedimientos en el diagnóstico y seguimiento del asma. SEPAR. Editorial Respira. ISBN: 978-84-124841-1-3. Document type: Book chapter.
Crespo Lessmann, Ástrid. proGEMA 5.2. SEPAR. Luzán. ISBN:978-84-19069-12-2. Depósito Legal: M-17967-2022. Document type: Book chapter.
Curto E, Mateus EF, Crespo A, Osuna R, Ujaldon C, Garcia A, Galvan P, Soto L, Ramos D, Plaza V. Identification of Two Eosinophil Subsets in Induced Sputum from Patients with Allergic Asthma According to CD15 and CD66b Expression. International Journal of Environmental Research and Public Health. 2022; 19(20):13400. DOI:10.3390/ijerph192013400. PMID:36293979. Document type: Article.
Curto E, Ojanguren Í, Blanco M, Crespo A, Plaza V, Cisneros C, Serrano J, el Grupo Y. How to Approach Non Eosinophilic Asthma? Results of a Survey Conducted by the SEPAR Emerging Asthma Group. Open Respiratory Archives. 2022; 4(1):100149. DOI:10.1016/j.opresp.2021.100149. Document type: Article.
De la Rosa D (2022). Aspectos farmacoeconómicos de los antibióticos inhalados. In: Antibióticos inhalados. Editorial Neumología y Salud. ISBN: 978-84-945694-5-6. Document type: Book chapter.
De la Rosa D, Castillo D, Gutiérrez F (2022). Seguimiento del paciente post-COVID. In: Barreiro E. Fisiopatología de la COVID-19 en diferentes órganos y sistemas. Editorial Elsevier. ISBN: 978-84-1382-160-3. Document type: Book chapter.
de la Rosa D, GARCIA MM. Bronchiectasis exacerbations: certainties and future challenges. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE. 2022; 26(7). DOI:10.5588/ijtld.22.0185. PMID:35768930. IF:4 (Q2/5D). Document type: Editorial material.
de la Rosa D, Suárez G, Golpe R, Martinez MA, Carro LM. Inhaled Colistimethate Sodium in the Management of Patients with Bronchiectasis Infected by Pseudomonas aeruginosa: A Narrative Review of Current Evidence. Infection and Drug Resistance. 2022; 15. DOI:10.2147/IDR.S318173. IF:3,9 (Q2/4D). Document type: Review.
De Llano LP, Rivas DD, Malanda NM, Moral VP, Blanco J, Munoz M, Garcia I, Campos RMD, Martinez E, Mena AH, Cosio BG, Galo AP, Serrano CC. The Response to Biologics is Better in Patients with Severe Asthma Than in Patients with Asthma-COPD Overlap Syndrome. Journal of Asthma and Allergy. 2022; 15. DOI:10.2147/JAA.S338467. PMID:35330786. IF:3,2 (Q3/6D). Document type: Article.
Domínguez J, Plaza V, Li VW, Fonseca E, Cea L, Martin A, Sánchez M, Brady JE, Schelfhout J. Prevalence of chronic cough and patient characteristics in adults in Spain: A population-based cross-sectional survey. Chronic Respiratory Disease. 2022; 19:14799731221098722. DOI:10.1177/14799731221098722. PMID:35620851. IF:4,1 (Q2/4D). Document type: Article.
Franquet T, Franks TJ, Lee KS, Marchiori E, Mazzini S, Gimenez A, Johkoh T, Cho JH, Galvin JR. Human Oncoviruses and Thoracic Tumors: Understanding the Imaging Findings. 2022; 42(3). DOI:10.1148/rg.210157. PMID:35363552. IF:5,5 (Q1/2D). Document type: Article.
Franquet T, Gimenez A, Ketai L, Mazzini S, Rial A, Pomar V, Domingo P. Air trapping in COVID-19 patients following hospital discharge: retrospective evaluation with paired inspiratory/expiratory thin-section CT. EUROPEAN RADIOLOGY. 2022; 32(7). DOI:10.1007/s00330-022-08580-2. PMID:35226158. IF:5,9 (Q1/2D). Document type: Article.
Franquet T, Palleiro AG. Idiopathic pleuroparenchymal fibroelastosis. 2022; 64. DOI:10.1016/j.rx.7027.10.004. PMID:36737168. Document type: Article.
Garcia F, Alcazar B, Castillo D, Cilloniz C, Garcia A, Leiro V, Lojo I, Padilla A, Quezada CA, Rodriguez JA, Sanchez M, Sibila O, Martinez MA. Biological Biomarkers in Respiratory Diseases. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(4). DOI:10.1016/j.arbres.2022.01.010. PMID:35312522. IF:8 (Q1/2D). Document type: Article.
Gimenez A, Mazzini S, Franquet T. Radiological reports for interstitial lung disease. Radiologia. 2022; 64. DOI:10.1016/j.rx.2022.01.007. Document type: Article.
Gimenez AG, Mazzini SP, Franquet YT. Basic hrct patterns in diffuse interstitial lung disease. Radiologia. 2022; 64. DOI:10.1016/j.rx.2022.10.003. PMID:36737161. Document type: Article.
Gimenez S, Farre A, Morente F, Videla L, Gutierrez M, Clos S, Fernandez A, Blanco M, Altuna M, Pegueroles J, Asensio A, Benejam B, Batista M, Barroeta I, Fortuna A, Fortea J, Mayos M. Feasibility and Long-Term Compliance to Continuous Positive Airway Pressure Treatment in Adults With Down Syndrome, a Genetic Form of Alzheimer’s Disease. Frontiers in Neuroscience. 2022; 16:838412. DOI:10.3389/fnins.2022.838412. PMID:35431793. IF:4,3 (Q2/4D). Document type: Article.
Gonzalez J, Carmona P, Gracia E, Benitez ID, Anton A, Balana A, Diaz SB, Bernadich O, Cordoba A, Embid C, Espallargues M, Lujan M, Marti S, Castillo M, Tarrega J, Barbe F, Escarrabill J. Cluster Analysis of Home Mechanical Ventilation in COPD Patients: A Picture of the Real World and Its Impact on Mortality. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(9). DOI:10.1016/j.arbres.2021.12.015. PMID:35312537. IF:8 (Q1/2D). Document type: Article.
Herrera E, Ortega VE, Ampleford EJ, Sio YY, Granell R, de Roos E, Terzikhan N, Vergara EE, Hernandez N, Perez J, Martin E, Lorenzo F, Hashimoto S, Brinkman P, Jorgensen AL, Yan Q, Forno E, Vijverberg SJ, Lethem R, Espuela A, Gorenjak M, Eng C, Gonzalez R, Hernandez JM, Poza P, Sardon O, Corcuera P, Hawkins GA, Marsico A, Bahmer T, Rabe KF, Hansen G, Kopp MV, et al. [Plaza V]. Multi-ancestry genome-wide association study of asthma exacerbations. PEDIATRIC ALLERGY AND IMMUNOLOGY. 2022; 33(6):e13802. DOI:10.1111/pai.13802. PMID:35754128. IF:4,4 (Q1/1D). Document type: Article.
Martinez BC, Palleiro AG, Florindez SPM. CYSTIC LUNG DISEASE. Radiologia. 2022; 64. DOI:10.1016/j.rx.7027.09.008. PMID:36737165. Document type: Article.
Martinez MA, Faner R, Oscullo G, la Rosa D, Soler JJ, Ballester M, Muriel A, Agusti A. Chronic Bronchial Infection Is Associated with More Rapid Lung Function Decline in Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society. 2022; 19(11). DOI:10.1513/AnnalsATS.202108-974OC. PMID:35666811. IF:8,3 (Q1/2D). Document type: Article.
Martinez MA, Olveira C, Giron R, Garcia M, Maiz L, Sibila O, Golpe R, Mendez R, Hermosa JLR, Barreiro E, Prados C, Lopez JR, de la Rosa D. Peripheral Neutrophil-to-Lymphocyte Ratio in Bronchiectasis: A Marker of Disease Severity. 2022; 12(10):1399. DOI:10.3390/biom12101399. PMID:36291608. IF:5,5 (Q1/3D). Document type: Article.
Martinez MA, Oscullo G, Ponce S, Pastor E, Orosa B, Catalán P, Martinez A, Hernandez L, Muriel A, Chiner E, Vigil L, Carmona C, Mayos M, Garcia A, Gomez JD, Beauperthuy T, Bekki A, Gozal D. Effect of continuous positive airway pressure in very elderly with moderate-to-severe obstructive sleep apnea pooled results from two multicenter randomized controlled trials. SLEEP MEDICINE. 2022; 89. DOI:10.1016/j.sleep.2021.11.009. PMID:34915264. IF:4,8 (Q1/3D). Document type: Article.
Mediano O, Mangado NG, Montserrat JM, Alonso ML, Almendros I, Alonso A, Barbe F, Borsini E, Caballero C, Cano I, Villafranca FD, Carmona C, Alduenda JLC, Chiner E, Guevara J, de Manuel L, Duran J, Farre R, Franceschini C, Gaig C, Ramos PG, Garcia F, Garmendia O, Garcia TG, Pondal SG, Rodrigo MBH, Lecube A, Madrid JA, Lozano LM, Carrasco JLM, Masa JF, et al. [Mayos M, Rigau D]. International Consensus Document on Obstructive Sleep Apnea. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(1). DOI:10.1016/j.arbres.2021.03.017. PMID:33875282. IF:8 (Q1/2D). Document type: Article.
Mediano O, Mangado NG, Montserrat JM, Alonso ML, Almendros I, Alonso A, Barbe F, Borsini E, Caballero C, Cano I, Villafranca FD, Carmona C, Alduenda JLC, Chiner E, Guevara J, de Manuel L, Duran J, Farre R, Franceschini C, Gaig C, Ramos PG, Garcia F, Garmendia O, Garcia TG, Pondal SG, Rodrigo MBH, Lecube A, Madrid JA, Lozano LM, Carrasco JLM, Masa JF, et al. [Mayos M, Rigau D]. International consensus document on obstructive sleep apnea. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(1). DOI:10.1016/j.arbres.2021.03.027. PMID:35245183. IF:8 (Q1/2D). Document type: Article.
Molina M, Buendia I, Castillo D, Caro F, Valenzuela C, Selman M. Diagnostic and Therapeutic Developments in Progressive Pulmonary Fibrosis. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(5). DOI:10.1016/j.arbres.2021.12.017. PMID:35312511. IF:8 (Q1/2D). Document type: Article.
Mulet M, Osuna R, Zamora C, Porcel JM, Nieto JC, Perea L, Pajares V, Munoz AM, Calvo N, Sorolla MA, Vidal S. Influence of Malignant Pleural Fluid from Lung Adenocarcinoma Patients on Neutrophil Response. Cancers. 2022; 14(10):2529. DOI:10.3390/cancers14102529. PMID:35626131. IF:5,2 (Q2/3D). Document type: Article.
Oliveira LFD, Mallafré C, Giner J, Perea L, Sibila O, Pardo A, Marco S. Breath analysis using electronic nose and gas chromatography-mass spectrometry: A pilot study on bronchial infections in bronchiectasis. CLINICA CHIMICA ACTA. 2022; 526. DOI:10.1016/j.cca.2021.12.019. IF:5 (Q1/2D). Document type: Article.
Palones E, Pajares V, Lopez L, Castillo D, Torrego A. Sarcoidosis following SARS-CoV-2 infection: Cause or consequence?. Respirology Case Reports. 2022; 10(6):e0955. DOI:10.1002/rcr2.955. PMID:35505665. Document type: Article.
Paredes AM, Alvarez JM, Perez N, Puy C, Penacoba P, Segura M, Anton A. Controlled cycles in spontaneous-timed noninvasive ventilation: Incidence and associated factors. RESPIRATORY MEDICINE. 2022; 204:107005. DOI:10.1016/j.rmed.2022.107005. PMID:36270154. IF:4,3 (Q2/4D). Document type: Article.
Paris JM, Sanchez CA, Blanco M, Dominguez J, Donaire JG, Marcos NS, Plaza V. Current expert opinion and attitudes to optimize telemedicine and achieve control in patients with asthma in post-pandemic era: The COMETA consensus. Atencion Primaria. 2022; 54(12):102492. DOI:10.1016/j.aprim.2022.102492. PMID:36272223. IF:2,5 (Q3/6D). Document type: Article.
Peñacoba P, Fortuna AM, Mayos M. Management of obstructive sleep apnea in primary care in relation to the new international consensus document. Open Respiratory Archives. 2022; 4(1):100150. DOI:10.1016/j.opresp.2021.100150. Document type: Editorial material.
Peñacoba P, Llauger MA, Fortuna AM, Flor X, Sampol G, Pedro AM, Grau N, Santiveri C, Juvanteny J, Aoiz JI, Bayó J, Lloberes P, Mayos M, Domínguez L, Valverde P, Santos MªÁ, Farga MªM, Reverté M, Argemí N, Medrano C, Puig M, the PASHOS Working G. A new tool to screen patients with severe obstructive sleep apnea in the primary care setting: a prospective multicenter study. BMC Pulmonary Medicine. 2022; 22(1):38. DOI:10.1186/s12890-022-01827-0. PMID:35033055. IF:3,1 (Q3/7D). Document type: Article.
Perrot JC, Segura M, Beranuy M, Gich I, Nadal MJ, Pintor A, Terra J, Ramirez E, Paz LD, Bascuñana H, Plaza V, Güell R. Comparison of post-COVID symptoms in patients with different severity profiles of the acute disease visited at a rehabilitation unit. PLoS One. 2022; 17:e0274520. DOI:10.1371/journal.pone.0274520. PMID:36112577. IF:3,7 (Q2/4D). Document type: Article.
Plaza V, Alobid I, Alvarez C, Blanco M, Ferreira J, Garcia G, Gomez A, Gomez F, Hidalgo A, Korta J, Molina J, Pellegrini FJ, Perez M, Plaza J, Praena M, Quirce S, Sanz J. Spanish Asthma Management Guidelines (GEMA) VERSION 5.1. Highlights and Controversies. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(2). DOI:10.1016/j.arbres.2021.05.010. PMID:34167859. IF:8 (Q1/2D). Document type: Article.
Quint JK, Arnetorp S, Kocks JWH, Kupczyk M, Nuevo J, Plaza V, Cabrera C, Raherison C, Walker B, Penz E, Gilbert I, Lugogo NL, van der Valk RJP, Fong A, Qian C, Fabry C, Touboul C, Brzostek D, Maslova E, Surmont F, Goike H, Gandhi H, Korevaar JC, Tkacz J, Johnston K, Peres da Costa K, van L, Vervloet M, Pollack M, Hernandez P, Boarino S, Noorduyn SG, Beekman W, Weesie YM, SABINA North American and European Study C. Short-Acting Beta-2-Agonist Exposure and Severe Asthma Exacerbations: SABINA Findings From Europe and North America. Journal of Allergy and Clinical Immunology-In Practice. 2022; 10(9). DOI:10.1016/j.jaip.2022.02.047. PMID:35364341. IF:9,4 (Q1/1D). Document type: Article.
Rivera CM, Crespo A, Arismendi E, Munoz M, Aguilar X, Ausin P, Bobolea I, Duch GD, Teixido RP, Talaverano GS, Sabardia AS, Gall XM. Challenges for asthma units in response to COVID-19: a qualitative group dynamics analysis. JOURNAL OF ASTHMA. 2022; 59(6). DOI:10.1080/02770903.2021.1917605. PMID:33882776. IF:1,9 (Q4/8D). Document type: Article.
Rodrigo A, Alonso A, Barril S, Farinas O, Gueell E, Pascual A, Castillo D. Impact of Early Referral to Palliative Care in Patients with Interstitial Lung Disease. JOURNAL OF PALLIATIVE MEDICINE. 2022; 25(9). DOI:10.1089/jpm.2021.0458. PMID:35714348. IF:2,8 (Q3/6D). Document type: Article.
Rodrigo A, Giner J, Perea L, Merino JL, Albacar N, Solarat B, Castillo D, Faner R, Agusti A, Sibila O. Predicting Early Hospital Readmissions in COPD Patients Using an Electronic Nose. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(9). DOI:10.1016/j.arbres.2022.01.015. PMID:35312493. IF:8 (Q1/2D). Document type: Letter.
Romano A, Ruiz I, de la Rosa D, Peñacoba P. Tapia’s syndrome and pronation in a patient with pneumonia due to COVID-19: About a case. ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA. 2022; 40(9). DOI:10.1016/j.eimc.2021.06.019. PMID:35729048. IF:2,5 (Q4/8D). Document type: Letter.
Romero JD, Blanco M, Serrano CC, Diaz D, Piqueres RF, Lopez V, Merino V, Soto L, Dominguez J. Support for Home Administration of Biological Therapy in Patients With Severe Asthma: BioCart (c). JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2022; 32(6). DOI:10.18176/jiaci.0786. PMID:35088761. IF:7,2 (Q1/2D). Document type: Article.
Sanchez M, Gracia E, Benitez ID, Zapater A, Torres G, Sanchez A, Aldoma A, de Batlle J, Targa A, Abad J, Duran J, Urrutia A, Mediano O, Masdeu MJ, Ordax E, Masa JF, De la Pena M, Mayos M, Coloma R, Montserrat JM, Chiner E, Minguez O, Pascual L, Cortijo A, Martinez D, Dalmases M, Lee CH, McEvoy RD, Barbe F, Spanish N. Long-Term Effect of Obstructive Sleep Apnea and Continuous Positive Airway Pressure Treatment on Blood Pressure in Patients with Acute Coronary Syndrome A Clinical Trial. Annals of the American Thoracic Society. 2022; 19(10). DOI:10.1513/AnnalsATS.202203-260OC. PMID:35442180. IF:8,3 (Q1/2D). Document type: Article.
Sapina E, Benitez ID, Torres G, Fortuna AM, Marquez PP, Masa JF, Drager LF, Cabrini M, Felez M, Vazquez S, Abad J, Lee C, Garcia F, Casitas R, Mediano O, Peralta SR, Martinez D, Sanchez M, Barbe F, Dalmases M. Effect of CPAP treatment on BP in resistant hypertensive patients according to the BP dipping pattern and the presence of nocturnal hypertension. HYPERTENSION RESEARCH. 2022; 45(3). DOI:10.1038/s41440-021-00762-7. PMID:34952953. IF:5,4 (Q2/3D). Document type: Article.
Serra C, Torrego A, Pajares V, Millan P, Barril S, Alonso A, Navarro M, Lopez L, Franquet T, Castillo D. Bronchoalveolar lavage complements transbronchial cryobiopsy diagnosis in diffuse interstitial lung diseases. Journal Of Bronchology And Interventional Pulmonology. 2022; 29(1). DOI:10.1097/LBR.0000000000000770. PMID:33828048. Document type: Article.
Torrego A, Muñoz AM, Lucena CM, Castro P, López L, Badía JR, Betbesé A, Ramirez J, Andreo F, Fernández M-T, Fabra M, Pajares V, Agustí C. Safety and Feasibility of Transbronchial Cryobiopsy in Mechanically Ventilated Patients. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(8). DOI:10.1016/j.arbres.2021.11.005. PMID:35312520. IF:8 (Q1/2D). Document type: Letter.
Torrego A, Pajares V, Maldonado F, Hetzel J. Transbronchial Cryobiopsy Bohemian Rhapsody. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(8). DOI:10.1016/j.arbres.2021.08.004. PMID:35312593. IF:8 (Q1/2D). Document type: Editorial material.
Villar F, de la Rosa D, Fariñas F, Jiménez CA. Immunosenescence, Immune Fitness and Vaccination Schedule in the Adult Respiratory Patient. Open Respiratory Archives. 2022; 4(3):100181. DOI:10.1016/j.opresp.2022.100181. Document type: Review.
Villegas DC, Barril S, Giner J, Millan P, Rodrigo A, Merino JL, Sibila O. Study of Diffuse Interstitial Lung Disease With the Analysis of Volatile Particles in Exhaled Air. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(1). DOI:10.1016/j.arbres.2021.03.014. PMID:33867204. IF:8 (Q1/2D). Document type: Letter.
Wang X, Villa C, Dobarganes Y, Olveira C, Girón R, García M, Máiz L, Sibila O, Golpe R, Menndez R, Rodríguez J, Prados C, Martinez MA, Rodriguez JL, De La Rosa D, Duran X, Garcia J, Barreiro E. Systemic Inflammatory Biomarkers Define Specific Clusters in Patients with Bronchiectasis: A Large-Cohort Study. 2022; 10(2):225. DOI:10.3390/biomedicines10020225. PMID:35203435. IF:4,7 (Q1/3D). Document type: Article.
Wang XJ, Olveira C, Giron R, Garcia M, Maiz L, Sibila O, Golpe R, Menendez R, Rodriguez J, Prados C, Martinez MA, Rodriguez JL, de la Rosa D, Qin LY, Duran X, Garcia J, Barreiro E. Blood Neutrophil Counts Define Specific Clusters of Bronchiectasis Patients: A Hint to Differential Clinical Phenotypes. 2022; 10(5):1044. DOI:10.3390/biomedicines10051044. PMID:35625780. IF:4,7 (Q1/3D). Document type: Article.
Zapater A, Solelhac G, Sánchez A, Gracia E, Benitez ID, Torres G, De Batlle J, Haba J, Berger M, Abad J, Duran J, Urrutia A, Mediano O, Masdeu MJ, Ordax E, Masa JF, De la Peña M, Mayos M, Coloma R, Montserrat JM, Chiner E, Mínguez O, Pascual L, Cortijo A, Martínez D, Dalmases M, Lee C-H, McEvoy RD, Barbé F, Heinzer R, Sánchez M, Spanish N. Respiratory Polygraphy Patterns and Risk of Recurrent Cardiovascular Events in Patients With Acute Coronary Syndrome. Frontiers in Medicine. 2022; 9:870906. DOI:10.3389/fmed.2022.870906. PMID:35833104. IF:3,9 (Q2/4D). Document type: Article.

Publicacions 2021

Alserawan L, Penacoba P, Echevarria S, Castillo D, Ortiz E, Martinez L, Naranjo EM, Domingo P, Castellvi I, Juarez C, Mariscal A. Growth Differentiation Factor 15 (GDF-15): A Novel Biomarker Associated with Poorer Respiratory Function in COVID-19. Diagnostics. 2021; 11(11):1998. DOI:10.3390/diagnostics11111998. PMID:34829345. IF:3,992.
Cano E, Rodriguez TV, Martin I, Villegas DC, Garcia JJ, de Miguel EB, Robles A, Galvan MF, Roibas CM, Lara SH, Bermudo G, Moyano MG, Portal J, Torres JS, Narvaez J, Molina M. Diagnostic delay of associated interstitial lung disease increases mortality in rheumatoid arthritis. Scientific Reports. 2021; 11(1):9184. DOI:10.1038/s41598-021-88734-2. PMID:33911185. IF:4,996.
Casado P, Vazquez L, Botana M, Andrade MA, Ferreiro L, Capilla ES, Nunez A, de Miguel EB, Pajares V, Fernandez A. A rapid calprotectin test for the diagnosis of pleural effusion. PLoS One. 2021; 16(6):e0252714. DOI:10.1371/journal.pone.0252714. PMID:34111153. IF:3,752.
Casanova C, Gonzalez E, Martinez C, Cosio BG, Fuster A, Feu N, Solanes I, Cabrera C, Marin JM, Balcells E, Peces G, de Torres JP, Marin M, Calle M, Golpe R, Ojeda E, Divo M, Pinto V, Amado C, Lopez JL, Celli BR. Natural Course of the Diffusing Capacity of the Lungs for Carbon Monoxide in COPD Importance of Sex. CHEST. 2021; 160(2). DOI:10.1016/j.chest.2021.03.069. PMID:33878339. IF:10,262.
Castillo D, Barril S, Rodrigo A, Millan P, Suarez G, Alonso A, Franquet T, Lopez L, Castellvi I, Plaza V, Sibila O. EARLY HOSPITAL READMISSION INCREASES SHORT AND LONG – TERM MORTALITY IN PATIENTS WITH INTERSTITIAL LUNG DISEASE. SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES. 2021; 38(2):e2021021. DOI:10.36141/svdld.v38i2.10709. PMID:34316260. IF:1,803.
Corominas H, Castellvi I, Diaz C, Matas L, de la Rosa D, Mangues MA, Moya P, Pomar V, Benito N, Moga E, Hernandez N, Casademont J, Domingo P. Sarilumab (IL-6R antagonist) in critically ill patients with cytokine release syndrome by SARS-CoV2. MEDICINE. 2021; 100(19):e25923. DOI:10.1097/MD.0000000000025923. PMID:34106658. IF:1,817.
Corominas H, Castellvi I, Pomar V, Antonijoan R, Mur I, Matas L, Gich I, de Benito N, Laiz A, Castillo D, Villamarin L, Filella D, Mill AM, Quijada MA, Puig M, Casademont J, Domingo P. Effectiveness and safety of intravenous tocilizumab to treat COVID-19-associated hyperinflammatory syndrome: Covizumab-6 observational cohort. CLINICAL IMMUNOLOGY. 2021; 223:108631. DOI:10.1016/j.clim.2020.108631. PMID:33189888. IF:10,190.
Crespo A, Bernal S, del Rio E, Rojas E, Martinez C, Marina N, Pallares A, Pascual S, Garcia JL, Padilla A, Curto E, Cisneros C, Serrano J, Baiget M, Plaza V. Association of the CFTR gene with asthma and airway mucus hypersecretion. PLoS One. 2021; 16(6):e0251881. DOI:10.1371/journal.pone.0251881. PMID:34086689. IF:3,752.
Crespo A, Plaza V. Multidisciplinary consensus on sputum induction biosafety during the COVID-19 pandemic. ALLERGY. 2021; 76(8). DOI:10.1111/all.14697. PMID:33314245. IF:14,710.
de Torres JP, O’Donnell DE, Marin JM, Cabrera C, Casanova C, Marin M, Ezponda A, Cosio BG, Martinez C, Solanes I, Fuster A, Neder JA, Gonzalez J, Celli BR. Clinical and Prognostic Impact of Low Diffusing Capacity for Carbon Monoxide Values in Patients With Global Initiative for Obstructive Lung Disease I COPD. CHEST. 2021; 160(3). DOI:10.1016/j.chest.2021.04.033. PMID:33901498. IF:10,262.
Fischer JB, Frisk LK, Scholkmann F, Delgado R, Mayos M, Durduran T. Cerebral and systemic physiological effects of wearing face masks in adults. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021; 118(41):e2109111118. DOI:10.1073/pnas.2109111118. PMID:34607955. IF:12,779.
Garcia A, de la Rosa D, Oscullo G, Castillo D, Lopez R, Martinez MA. Coagulation disorders and thromboembolic disease in COVID-19 review of current evidence in search of a better approach. Journal of Thoracic Disease. 2021; 13(2). DOI:10.21037/jtd-20-3062. PMID:33717596. IF:3,005.
Martinez MA, Faner R, Oscullo G, de la Rosa D, Soler JJ, Ballester M, Muriel A, Agusti A. Risk Factors and Relation with Mortality of a New Acquisition and Persistence of Pseudomonas aeruginosa in COPD Patients. COPD-Journal of Chronic Obstructive Pulmonary Disease. 2021; 18(3). DOI:10.1080/15412555.2021.1884214. PMID:33941014. IF:2,069.
Martinez MA, Faner R, Oscullo G, la Rosa D, Soler JJ, Ballester M, Muriel A, Agusti A. Chronic bronchial infection and incident cardiovascular events in chronic obstructive pulmonary disease patients: A long-term observational study. RESPIROLOGY. 2021; 26(8). DOI:10.1111/resp.14086. PMID:34002922. IF:6,175.
Martinez MA, Villa C, Dobarganes Y, Giron R, Maiz L, Garcia M, Sibila O, Golpe R, Rodriguez J, Barreiro E, Rodriguez JL, Menendez R, Prados C, de la Rosa D, Olveira C. RIBRON: The spanish Online Bronchiectasis Registry. Characterization of the First 1912 Patients. ARCHIVOS DE BRONCONEUMOLOGIA. 2021; 57(1). DOI:10.1016/j.arbres.2019.12.021. PMID:32081438. IF:6,333.
Milagro J, Soto L, Giner J, Varon C, Laguna P, Bailon R, Plaza V, Gil E. Asthmatic subjects stratification using autonomic nervous system information. Biomedical Signal Processing and Control. 2021; 69:102802. DOI:10.1016/j.bspc.2021.102802. IF:5,076.
Millán P, Pajares V, Guerrero R, Villalba J, Torrego A. Recurrent Haemoptysis Secondary to Abnormal Arterial Supply to the Right Lower Lobe of the Lung. ARCHIVOS DE BRONCONEUMOLOGIA. 2021; 57(10). DOI:10.1016/j.arbres.2020.10.004. PMID:33223304. IF:6,333.
Navarro A, de la Rosa D, Esquinas C, Miravitlles M, Martinez MA, Almagro P. Evolution and Comparative Analysis of Hospitalizations in Spain Due to COPD and Bronchiectasis between 2004 and 2015. COPD-Journal of Chronic Obstructive Pulmonary Disease. 2021; 18(2). DOI:10.1080/15412555.2021.1896692. PMID:33729066. IF:2,069.
Perez de Llano LP, Davila I, Martinez E, Dominguez J, Almonacid C, Colas C, Garcia JL, Carmona L, de Yebenes MJG, Cosio BG, Torrego A, MENA AH. Development of a Tool to Measure the Clinical Response to Biologic Therapy in Uncontrolled Severe Asthma: The FEV1, Exacerbations, Oral Corticosteroids, Symptoms Score. Journal of Allergy and Clinical Immunology-In Practice. 2021; 9(7). DOI:10.1016/j.jaip.2021.01.033. PMID:33549843. IF:6,333.
Plaza V, Arnedillo A, Blanco M, Ignacio JM, Urrutia I. Consensus on the treatment of allergic asthma with sublingual house dust mite immunotherapy in the field of pneumology. Expert Review of Respiratory Medicine. 2021; 15(10). DOI:10.1080/17476348.2021.1942846. PMID:34128758. IF:4,300.
Plaza V, Giner J, Curto E, Alonso MB, Orue MI, Vega JM, Cosio BG. Assessing Adherence by Combining the Test of Adherence to Inhalers With Pharmacy Refill Records. JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2021; 31(1). DOI:10.18176/jiaci.0461. PMID:31599726. IF:8,185.
Posadas T, Oscullo G, Zaldivar E, Villa C, Dobarganes Y, Giron R, Olveira C, Maiz L, Garcia M, Sibila O, Golpe R, Rodriguez J, Barreiro E, Rodriguez JL, Menendez R, Prados C, de la Rosa D, Martinez MA. C-Reactive Protein Concentration in Steady-State Bronchiectasis: Prognostic Value of Future Severe Exacerbations. Data From the Spanish Registry of Bronchiectasis (RIBRON). ARCHIVOS DE BRONCONEUMOLOGIA. 2021; 57(1). DOI:10.1016/j.arbres.2019.12.017. PMID:32331706. IF:6,333.
Reyes D, Alonso J, Mayos M, Nunez C, Llauger J, Belmonte I, Pedrosa I, Segovia S, Diaz J. Correlation Between Respiratory Accessory Muscles and Diaphragm Pillars MRI and Pulmonary Function Test in Late-Onset Pompe Disease Patients. Frontiers in Neurology. 2021; 12:621257. DOI:10.3389/fneur.2021.621257. PMID:33732206. IF:4,086.
Rial MJ, Alvarez MJ, Arismendi E, Caballero ML, Canas JA, Cruz MJ, Gonzalez FJ, Luna JA, Martinez C, Mullol J, Munoz X, Olaguibel JM, Picado C, Plaza V, Quirce S, Romero C, Salgado FJ, Sastre B, Soto L, Valero A, Valverde M, Sastre J, del Pozo V. Clinical and inflammatory characteristics of patients with asthma in the Spanish MEGA project cohort. Clinical and Translational Allergy. 2021; 11(1):e12001. DOI:10.1002/clt2.12001. PMID:33900052. IF:5,657.
Rubio MC, Hermosa JLR, de Torres JP, Marin JM, Martinez C, Fuster A, Cosio BG, Peces G, Solanes I, Feu N, Lopez JL, Casanova C, CHAIN I. COPD Clinical Control: predictors and long-term follow-up of the CHAIN cohort. RESPIRATORY RESEARCH. 2021; 22(1):36. DOI:10.1186/s12931-021-01633-y. PMID:33541356. IF:7,162
Sebastiani M, Luppi F, Sambataro G, Villegas DC, Cerri S, Tomietto P, Cassone G, Bocchino M, Atienza B, Cameli P, Alvarado PM, Faverio P, Bargagli E, Vancheri C, Gonzalez MA, Clini E, Salvarani C, Manfredi A. Interstitial Lung Disease and Anti-Myeloperoxidase Antibodies: Not a Simple Association. Journal of Clinical Medicine. 2021; 10(12):2548. DOI:10.3390/jcm10122548. PMID:34207641. IF:4,964.
Shull JG, Pay MT, Lara Compte C, Olid M, Bermudo G, Portillo K, Sellarés J, Balcells E, Vicens-Zygmunt V, Planas-Cerezales L, Badenes-Bonet D, Blavia R, Rivera-Ortega P, Moreno A, Sans J, Perich D, Barril S, Esteban L, Garcia-Bellmunt L, Esplugas J, Suarez-Cuartin G, Bordas-Martinez J, Castillo D, Jolis R, Salvador I, Eizaguirre Anton S, Villar A, et al. Mapping IPF helps identify geographic regions at higher risk for disease development and potential triggers. Respirology. 2021;26(4):352-359. DOI:10.1111/resp.13973. PMID: 33167075. IF:6,175.
Tabar AI, Delgado J, Gonzalez E, Arroabarren E, Retes LS, Dominguez J. Recent Advances in Allergen-Specific Immunotherapy as Treatment for Allergic Asthma: A Practical Overview. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2021; 182(6). DOI:10.1159/000513811. PMID:33631755. IF:3,767.
Torrego A, Herth FJ, Munoz AM, Puente L, Facciolongo N, Bicknell S, Novali M, Gasparini S, Bonifazi M, Dheda K, Andreo F, Votruba P, Langton D, Flandes J, Fielding D, Bonta PI, Skowasch D, Schulz C, Darwiche K, McMullen E, Grubb GM, Niven R. Bronchial Thermoplasty Global Registry (BTGR): 2-year results. BMJ Open. 2021; 11(12):e053854. DOI:10.1136/bmjopen-2021-053854. PMID:34916324. IF:3,006.
Valero AL, Trigueros JA, Plaza V. Multidisciplinary consensus on inhaled therapy in asthma. Expert Review of Respiratory Medicine. 2021;15(3):425-434. DOI:10.1080/17476348.2021.1841639. PMID: 33170733. IF:4,300.
Villegas DC, Barril S, Giner J, Millan P, Rodrigo A, Merino JL, Sibila O. Study of diffuse interstitial lung disease with the analysis of volatile particles in exhaled air. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(1). DOI:10.1016/j.arbres.2021.03.023. IF:1,803.
Wang XJ, Villa C, Dobarganes Y, Olveira C, Giron R, Garcia M, Maiz L, Sibila O, Golpe R, Menendez R, Rodriguez J, Prados C, Martinez MA, Rodriguez JL, de la Rosa D, Duran X, Barreiro E. Differences in Nutritional Status and Inflammatory Biomarkers between Female and Male Patients with Bronchiectasis: A Large-Cohort Study. Biomedicines. 2021; 9(8):905. DOI:10.3390/biomedicines9080905. PMID:34440109. IF:4,757.
Wang XJ, Villa C, Dobarganes Y, Olveira C, Giron R, Garcia M, Maiz L, Sibila O, Golpe R, Menendez R, Rodriguez J, Prados C, Martinez MA, Rodriguez JL, de la Rosa D, Duran X, Garcia J, Barreiro E. Phenotypic Clustering in Non-Cystic Fibrosis Bronchiectasis Patients: The Role of Eosinophils in Disease Severity. International Journal of Environmental Research and Public Health. 2021; 18(16):8431. DOI:10.3390/ijerph18168431. PMID:34444179. IF:4,614.

MEDICINA TRANSLACIONAL

Malalties Respiratòries Cròniques (GREC)

Principals línies de recerca

Asma

Malaltia pulmonar obstructiva crònica (MPOC) i la insuficiència respiratòria

Síndrome d’Apnea-Hipopnea del Son (SAHOS)

Reptes

Coordinació del grup

Co-coordinador:

Membres

Publicacions 2022

Publicacions 2021

Principals línies de recerca

Asma

Malaltia pulmonar obstructiva crònica (MPOC) i la insuficiència respiratòria

Síndrome d’Apnea-Hipopnea del Son (SAHOS)

Reptes

Coordinació del grup

Co-coordinador:

Membres

Publicacions 2022

Publicacions 2021

Institut de recerca de l’hospital de la santa creu i sant pau