Sant Pau - Institut de Recerca

Principals línies de recerca

Insuficiència respiratòria aguda i ventilació artificial

Ventilació no invasiva.
Noves formes de ventilació: ventilació assistida proporcional i NAVA.
Decúbit pron en la síndrome de disfunció respiratòria aguda (SDRA).
Retirada de ventilació artificial.
Sistemes de ventilació d’experts.
La son i la ventilació artificial.
Mobilització primerenca i activa del pacient crític.
Eliminació de CO2 extracorpori en pacients amb SDRA.
Administració d’oxigen d’alt flux per cànula nasal en la fase posterior a la extubació.
Prevalença d’interaccions medicamentoses en la unitat de cures intensives.

Estudi de la utilitat de nous biomarcadors en pacients críticament malalts

BNP en la retirada de la ventilació mecànica.
Ús de la proteïna NGAL en el pronòstic renal dels pacients malalts crítics.
Control estricte de la glucèmia en pacients malalts crítics.
Profilaxi de la lesió de la mucosa gàstrica aguda en pacients malalts crítics.
Estudi dels efectes hemodinàmics de diferents fàrmacs antipirètics en pacients malalts crítics.
Influència del canvi de posició de decúbit supí a la pressió intraabdominal.

Reptes

Consolidar la investigació clínica i fisiològica en la ventilació en pacients crítics a través de xarxes multicèntriques i multinacionals.
Crear un grup estable i ben entrenat d’investigadors en aquesta disciplina.

Coordinació del grup

MORAN CHORRO, INDALECIO FGS
imoran@santpau.cat

Membres

Baldira Martinez De Irujo, Jaume FGS
Belles Casas, Ariadna FGS
Betbese Roig, Antoni Jordi FGS
Cordon Abalde, Alejandra FGS
Diaz Tormo, Carmen FGS
Flores Orella, Matias Nicolas FGS
Gomila Sintes, Carme FGS
Izura Gomez, Marta FGS
Mas Serra, Arantxa FGS
Nievas, Maria Veronica FGS
Rodriguez Farre, Nuria FGS
Santos Rodriguez, Jose Alberto FGS
Serrano Garcia, Maria Angeles FGS
Suarez Montero, Juan Carlos FGS
Torrens Sonet, Maria FGS
Vera Artazcoz, Paula FGS
Zapata Fenor, Luis FGS

Publicacions 2022

(JIF 2022)

Amado L, Rodríguez R, Bellani G, Pham T, Fan E, Madotto F, Laffey JG, Pesenti A, Brochard L, Esteban A, Gattinoni L, van F, Ranieri M, Rubenfeld G, Taylor B, Slutsky AS, Rios F, Van F, Sottiaux T, Lora FS, Azevedo LC, Bugedo G, Gonzalez M, Silesky J, Cerny V, Jibaja M, Wrigge H, Matamis D, Ranero JL, Amin P, Hashemian SM, Clarkson K, Kurahashi K, Villagomez A, et al. [Mancebo J]. Mechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study. Journal of Intensive Care. 2022; 10(1):55. DOI:10.1186/s40560-022-00648-x. IF:7,1 (Q1/3D). Document type: Article.
Baldirà J, Morán I, Marruecos L. Banisteriopsis caapi/Psychotria viridis. In: Toxic Plants. Reports, studies and research 2022. Ministry of Health. Publications Center, 2022; 49-52. https://cpage.mpr.gob.es NIPO en linea: 133-22-020-8. Document type: Book chapter.
Baldirà J, Morán I, Marruecos L. Coriaria myrtifolia. Roldón. In: Toxic Plants. Reports, studies and research 2022. Ministry of Health. Publications Center, 2022; 85-87. https://cpage.mpr.gob.es. NIPO en linea: 133-22-020-8. Document type: Book chapter.
Baldirà J, Morán I, Marruecos L. Hydrangea macrophylla. In: Toxic Plants. Reports, studies and research 2022. Ministry of Health. Publications Center, 2022; 124-126. https://cpage.mpr.gob.es NIPO en linea: 133-22-020-8. Document type: Book chapter.
Baldirà J, Morán I, Marruecos L. Narcissus spp. I: Toxic Plants. Reports, studies and research 2022. Ministry of Health. Publications Center, 2022; 172-174. https://cpage.mpr.gob.es. NIPO en linea: 133-22-020-8. Document type: Book chapter.
Baldirà J, Morán I, Marruecos L. Oenanthe crocata. Nabo del diablo. In: Toxic Plants. Reports, studies and research 2022. Ministry of Health. Publications Center, 2022; 184-187. https://cpage.mpr.gob.es. NIPO en linea: 133-22-020-8. Document type: Book chapter.
Baldirà J, Morán I, Marruecos L. Senecio jacobea. Hierba de Santiago. In: Toxic Plants. Reports, studies and research 2022. Ministry of Health. Publications Center, 2022; 222-224. https://cpage.mpr.gob.es. NIPO en linea: 133-22-020-8. Document type: Book chapter.
Belvís R, Morollón N, Cortés E, Morán I. Tabún, sarín, somán, VX y novichoks: agentes neurotóxicos organofosforados con finalidad bélica o criminal. 2022; 17(2). DOI:10.24875/KRANION.M22000030. Document type: Review.
Brault C, Mancebo J, Montero JCS, Bentall T, Burns K, Piraino T, Lellouche F, Bouchard PA, Charbonney E, Carteaux G, Maraffi T, Beduneau G, Mercat A, Skrobik Y, Zuo F, Lafreniere M, Thorpe K, Brochard L, Bosma KJ. The PROMIZING trial enrollment algorithm for early identification of patients ready for unassisted breathing. CRITICAL CARE. 2022; 26(1):188. DOI:10.1186/s13054-022-04063-4. PMID:35739553. IF:15,1 (Q1/1D). Document type: Article.
Chastre J, François B, Bourgeois M, Komnos A, Ferrer R, Rahav G, De Schryver N, Lepape A, Koksal I, Luyt C-E, Sánchez M, Torres A, Eggimann P, Koulenti D, Holland TL, Ali O, Shoemaker K, Ren P, Sauser J, Ruzin A, Tabor DE, Akhgar A, Wu Y, Jiang Y, DiGiandomenico A, Colbert S, Vandamme D, Coenjaerts F, Malhotra S, Timbermont L, Oliver A, Barraud O, et al. [Vera P]. Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial. CRITICAL CARE. 2022; 26(1):355. DOI:10.1186/s13054-022-04204-9. PMID:36380312. IF:15,1 (Q1/1D). Document type: Article.
Co-author of the Book: Algorithms of nutritional intervention in the critically ill Publishing House: Health and Editions, S.L. Edition: Second. ISBN: 978‑84‑18351‑74‑7 Publication date: 01/06/2022. List of authors in alphabetical order, page 6 (Paula Vera). Book pages: 1-94. Document type: Book.
Frutos F, Peñuelas O, Muriel A, Mancebo J, García A, de Pablo R, Valledor M, Ferrer M, León M, Quiroga JM, Temprano S, Vallverdú I, Fernández R, Gordo F, Anzueto A, Esteban A. Mechanical ventilation in Spain, 1998-2016: changes in the disconnection of mechanical ventilation. Medicina Intensiva. 2022; 46(7). DOI:10.1016/j.medin.2021.04.005. PMID:34092422. IF:3 (Q3/7D). Document type: Article.
Gomila Sintes C, Bernal S, Rojas E, Flores Orella MN, Leoz P, Betbesé Roig AJ. Favism in the elderly. Archives of Clinical and Medical Case Reports. 2022;6(4):582-585. DOI: 10.26502/acmcr.96550521. Document type: Article.
Lopez JC, Grau T, Trujillano J, Garcia C, Mor E, Bordeje ML, Portugal E, Lorencio C, Vera P, Macaya L, Martinez JF, Mateu L, Gero M, Gastaldo R, Vila B, Flordelis JL, Montejo JC, Servia L, ENPIC GRP. The Effect of Enteral Immunonutrition in the Intensive Care Unit: Does It Impact on Outcomes?. 2022; 14(9):1904. DOI:10.3390/nu14091904. PMID:35565870. IF:5,9 (Q1/2D). Document type: Article.
Maddali MV, Churpek M, Rezoagli E, Zhuo H, Zhao W, He J, Delucchi KL, Wickersham N, McNeil JB, Jauregui A, Ke S, Vessel K, Gomez A, Hendrickson CM, Kangelaris KN, Sarma A, Leligdowicz A, Liu KD, Matthay MA, Ware LB, Laffey JG, Bellani G, Calfee CS, Sinha P, Rios F, Van F, Sottiaux T, Lora FS, Azevedo LC, Fan E, Bugedo G, Qiu H, Gonzalez M, Silesky J, Cerny V, et al. [Mancebo J]. Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis. Lancet Respiratory Medicine. 2022; 10(4). DOI:10.1016/S2213-2600(21)00461-6. PMID:35026177. IF:76,2 (Q1/1D). Document type: Article.
Maggiore SM, Jaber S, Grieco DL, Mancebo J, Zakynthinos S, Demoule A, Ricard J-D, Navalesi P, Vaschetto R, Hraiech S, Klouche K, Frat J-P, Lemiale V, Fanelli V, Chanques G, Natalini D, Ischaki E, Reuter D, Morán I, Combe BL, Longhini F, De Gaetano A, Ranieri VM, Brochard LJ, Antonelli M, RINO Trial Study G. High-Flow Versus VenturiMask Oxygen Therapy to Prevent Reintubation in Hypoxemic Patients after Extubation: A Multicenter Randomized Clinical Trial. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022; 206(12). DOI:10.1164/rccm.202201-0065OC. PMID:35849787. IF:24,7 (Q1/1D). Document type: Article.
Mateos A, Betbesé AJ, Guix EM. Fundamental concepts for the management of continuous replacement therapies. Enfermeria Intensiva. 2022; 33. DOI:10.1016/j.enfi.2021.06.003. Document type: Review.
Morales L, Mancebo J, Del Sorbo L. Hypercapnia and extracorporeal carbon dioxide removal (ECCO2R) in the acute respiratory distress syndrome. Signa Vitae. 2022; 18(5). DOI:10.22514/sv.2022.046. IF:1,1 (Q4/9D). Document type: Review.
Munshi L, Mancebo J, Brochard LJ. Noninvasive Respiratory Support for Adults with Acute Respiratory Failure. NEW ENGLAND JOURNAL OF MEDICINE. 2022; 387(18). DOI:10.1056/NEJMra2204556. PMID:36322846. IF:158,5 (Q1/1D). Document type: Review.
Nasa P, Azoulay E, Chakrabarti A, Divatia JV, Jain R, Rodrigues C, Rosenthal VD, Alhazzani W, Arabi YM, Bakker J, Bassetti M, De Waele J, Dimopoulos G, Du B, Einav S, Evans L, Finfer S, Guerin C, Hammond NE, Jaber S, Kleinpell RM, Koh Y, Kollef M, Levy MM, Machado FR, Mancebo J, Martin I, Mer M, Niederman MS, Pelosi P, Perner A, Peter JV, Phua J, Piquilloud L, Pletz MW, Rhodes A, Schultz MJ, Singer M, Timsit JF, Venkatesh B, Vincent JL, Welte T, Myatra S. Infection control in the intensive care unit: expert consensus statements for SARS-CoV-2 using a Delphi method. LANCET INFECTIOUS DISEASES. 2022; 22(3):e74-e87. DOI:10.1016/S1473-3099(21)00626-5. PMID:34774188. IF:56,3 (Q1/1D). Document type: Review.
Pisani L, Algera AG, Neto AS, Azevedo LC, Paulus F, de Abreu MG, Pelosi P, Dondorp AM, Bellani G, Laffey JG, Schultz MJ, Martinez A, Leal L, Jorge A, de Oliveira M, Neto JA, Piras C, Moreira CL, Braga P, Dalcomune DM, Ribeiro de Carvalho AG, Gondim LAR, Castelo Branco Reis LM, da Cunha Ribeiro D, de Assis L, Campos RS, Fernandez Versiani dos Anjos JC, Bruzzi F, et al. [Mancebo J]. Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute respiratory distress syndrome: a pooled analysis of four observational studies. Lancet Global Health. 2022; 10(2). DOI:10.1016/S2214-109X(21)00485-X. PMID:34914899. IF:34,3 (Q1/1D). Document type: Article.
Riera P, Sole N, Suarez JC, Lopez PA, Fonts N, Rodriguez N, de Gamarra EF, Moran I. Drug-drug interactions in an intensive care unit and comparison of updates in two databases. Farmacia Hospitalaria. 2022; 46(5). DOI:10.7399/fh.13180. PMID:36183229. Document type: Article.
Sassoon CS, Mancebo J. The Double-edged Sword of Reverse Triggering: Impact on the Diaphragm. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022; 205(6). DOI:10.1164/rccm.202201-0099ED. PMID:35139008. IF:24,7 (Q1/1D). Document type: Editorial material.
Servia L, Lopez JC, Grau T, Trujillano J, Bordeje ML, Mor E, Portugal E, Lorencio C, Montejo JC, Vera P, Macaya L, Martinez JF, Iglesias R, Monge D, Flordelis JL, Llorente B, Menor EM, de Lagran IM, Yebenes JC. Evaluation of Nutritional Practices in the Critical Care patient (The ENPIC study): Does nutrition really affect ICU mortality?. Clinical Nutrition Espen. 2022; 47. DOI:10.1016/j.clnesp.2021.11.018. PMID:35063222. Document type: Article.
Suárez JC, Caballero AC, Martín L, Mancebo J. Immune effector cell-associated neurotoxicity syndrome: A therapeutic approach in the critically ill. Medicina Intensiva. 2022; 46(4). DOI:10.1016/j.medin.2020.06.014. PMID:32873409. IF:3 (Q3/7D). Document type: Article.
Torrego A, Muñoz AM, Lucena CM, Castro P, López L, Badía JR, Betbesé A, Ramirez J, Andreo F, Fernández M-T, Fabra M, Pajares V, Agustí C. Safety and Feasibility of Transbronchial Cryobiopsy in Mechanically Ventilated Patients. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(8). DOI:10.1016/j.arbres.2021.11.005. PMID:35312520. IF:8 (Q1/2D). Document type: Letter.
Vidal P, Díaz E, Aguilar E, Amezaga R, Ballesteros MÁ, Bodí MA, Bordejé ML, Garnacho J, García M, López M, Martín I, Ochagavía A, Ramírez P, Alcántara S, Andaluz D, Badallo O, Barrasa H, Borges M, Castellanos Á, Estella Á, Ferrer R, Fraile V, Fuset M, Giménez C, González C, Hernández A, Igeño JC, Iglesias D, Jiménez JJ, Llanos C, Llompart JA, López V, et al. [Zapata L]. Recommendations for the management of critically ill patients with COVID-19 in Intensive Care Units. Medicina Intensiva. 2022; 46(2). DOI:10.1016/j.medin.2021.08.011. PMID:34545260. IF:3 (Q3/7D). Document type: Article.
Vidal P, Díaz E, Aguilar E, Amezaga R, Ballesteros MÁ, Bodí MA, Bordejé ML, Garnacho J, García M, López M, Martín I, Ochagavía A, Ramírez P, Alcántara S, Andaluz D, Badallo O, Barrasa H, Borges M, Castellanos Á, Estella Á, Ferrer R, Fraile V, Fuset M, Giménez C, González C, Hernández A, Igeño JC, Iglesias D, Jiménez JJ, Llanos C, Llompart JA, López V, et al. [Zapata L]. Recommendations for the management of critically ill patients with COVID-19 in Intensive Care Units. Medicina Intensiva. 2022; 46(2). DOI:10.1016/j.medine.2021.11.019. PMID:34903475. IF:3 (Q3/7D). Document type: Article/Practice guideline.
Wendel PD, Mas A, Gonzalez C, Ferrer R, Manez R, Masclans JR, Sandoval E, Vera P, Trenado J, Fernandez R, Sirvent JM, Martinez M, Ibarz M, Garro P, Lopera JL, Bodi M, Yebenes JC, Triginer C, Vallverdu I, Baro A, Bodi F, Saludes P, Valencia M, Roche F, Huerta A, Cambra FJ, Barbera C, Echevarria J, Penuelas O, Mancebo J, UCIsCAT GRP. Non-invasive oxygenation support in acutely hypoxemic COVID-19 patients admitted to the ICU: a multicenter observational retrospective study. CRITICAL CARE. 2022; 26(1):37. DOI:10.1186/s13054-022-03905-5. PMID:35135588. IF:15,1 (Q1/1D). Document type: Article.
Zapata L, Suarez JC, Flores MN, Morales EM, Segarra A, Santos JA. Acute cor pulmonale in patients with acute respiratory distress syndrome due to COVID-19. Medicina Intensiva. 2022; 46(11). DOI:10.1016/j.medin.2021.12.016. PMID:35079192. IF:3 (Q3/7D). Document type: Letter.

Publicacions 2021

Albaiceta GM, Brochard L, Santos CCD, Fernandez R, Georgopoulos D, Girard T, Jubran A, Lopez J, Mancebo J, Pelosi P, Skrobik Y, Thille AW, Wilcox ME, Blanch L. The central nervous system during lung injury and mechanical ventilation: a narrative review. BRITISH JOURNAL OF ANAESTHESIA. 2021; 127(4). DOI:10.1016/j.bja.2021.05.038. PMID:34340836. IF:11,719.
Astigarraga P, Lerma FA, Zambrano CB, Costa RG, Vidal FG, Navarro RD, Suarez CR, Pallas TA, Montero JG, Vera P, Alemparte E. Epidemiology and prognosis of patients with a history of cancer admitted to intensive care. A multicenter observational study. Medicina Intensiva. 2021; 45(6). DOI:10.1016/j.medin.2020.01.013. PMID:32307264. IF:2,799.
Berenguer J, Borobia AM, Ryan P, Rodriguez J, Bellon JM, Jarrin I, Carratala J, Pachon J, Carcas AJ, Yllescas M, Arribas JR, López J, Pascual P, Pomar V, Rabella N, Benito N, Domingo P, Bonfill X, Mancebo J, MARTIN A. Development and validation of a prediction model for 30-day mortality in hospitalised patients with COVID-19: the COVID-19 SEIMC score. THORAX. 2021; 76(9). DOI:10.1136/thoraxjnl-2020-216001. PMID:33632764. IF:9,102.
Grieco DL, Maggiore SM, Roca O, Spinelli E, Patel BK, Thille AW, Barbas CSV, De Acilu MG, Cutuli SL, Bongiovanni F, Amato M, Frat JP, Mauri T, Kress JP, Mancebo J, Antonelli M. Non-invasive ventilatory support and high-flow nasal oxygen as first-line treatment of acute hypoxemic respiratory failure and ARDS. INTENSIVE CARE MEDICINE. 2021; 47(8). DOI:10.1007/s00134-021-06459-2. PMID:34232336. IF:41,787.
Gutierrez B, del Toro MD, Borobia AM, Carcas A, Jarrin I, Yllescas M, Ryan P, Pachon J, Carratala J, Berenguer J, Arribas JR, Rodriguez J, López J, Pascual P, Pomar V, Rabella N, Benito N, Domingo P, Bonfill X, Puig M, Mancebo J, Martinez G. Identification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19: a multicentre cohort study. LANCET INFECTIOUS DISEASES. 2021; 21(6). DOI:10.1016/S1473-3099(21)00019-0. PMID:33636145. IF:71,421.
Johnstone J, Meade M, Lauzier F, Marshall J, Duan E, Dionne J, Arabi YM, Heels D, Thabane L, Lamarche D, Surette M, Zytaruk N, Mehta S, Dodek P, McIntyre L, English S, Rochwerg B, Karachi T, Henderson W, Wood G, Ovakim D, Herridge M, Granton J, Wilcox ME, Goffi A, Stelfox HT, Niven D, Muscedere J, Lamontagne F, D’Aragon F, St C, Ball I, et al. [Mancebo J]. Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients A Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2021; 326(11). DOI:10.1001/jama.2021.13355. PMID:34546300. IF:157,335.
Lomeli M, Cenzano LD, Torres L, Chavarria U, Poblano M, Tendillo F, Blanch L, Mancebo J. Aggressive alveolar recruitment in ARDS: more shadows than lights. Medicina Intensiva. 2021; 45(7). DOI:10.1016/j.medin.202.0.03.008. IF:2,799.
Madotto F, McNicholas B, Rezoagli E, Pham T, Laffey JG, Bellani G, Mancebo J, Pesenti A. Death in hospital following ICU discharge: insights from the LUNG SAFE study. CRITICAL CARE. 2021; 25(1):144. DOI:10.1186/s13054-021-03465-0. PMID:33849625. IF:19,334.
Mauri T, Foti G, Fornari C, Grasselli G, Pinciroli R, Lovisari F, Tubiolo D, Volta CA, Spadaro S, Rona R, Rondelli E, Navalesi P, Garofalo E, Knafelj R, Gorjup V, Colombo R, Cortegiani A, Zhou JX, D’Andrea R, Calamai I, Gonzalez AV, Roca O, Grieco DL, Jovaisa T, Bampalis D, Becher T, Battaglini D, Ge HQ, Luz M, Constantin JM, Ranieri M, Guerin C, Mancebo J, et al. Sigh in Patients With Acute Hypoxemic Respiratory Failure and ARDS The PROTECTION Pilot Randomized Clinical Trial. CHEST. 2021; 159(4). DOI:10.1016/j.chest.2020.10.079. PMID:33197403. IF:10,262.
Nasa P, Azoulay E, Khanna AK, Jain R, Gupta S, Javeri Y, Juneja D, Rangappa P, Sundararajan K, Alhazzani W, Antonelli M, Arabi YM, Bakker J, Brochard LJ, Deane AM, Du B, Einav S, Esteban A, Gajic O, Galvagno SM, Guerin C, Jaber S, Khilnani GC, Koh Y, Lascarrou JB, Machado FR, Malbrain MLNG, Mancebo J, McCurdy MT, McGrath BA, Mehta S, et al. Expert consensus statements for the management of COVID-19-related acute respiratory failure using a Delphi method. CRITICAL CARE. 2021; 25(1):106. DOI:10.1186/s13054-021-03491-y. PMID:33726819. IF:19,334.
Penuelas O, del Campo L, de Aledo A, Anon JM, Rodriguez C, Mancebo J, Vera P, Ballesteros D, Jimenez J, Maseda E, Figueira JC, Franco N, Algaba A, Aviles JP, Diaz R, Abad B, Canabal A, Abella A, Gordo F, Garcia J, Suarez JG, Cedeno J, Martinez B, Manteiga E, Martinez O, Blancas R, Bardi T, Pestana D, Lorente JA, Muriel A, Esteban A, Frutos F. Long-term survival of mechanically ventilated patients with severe COVID-19: an observational cohort study. Annals of Intensive Care. 2021; 11(1):143. DOI:10.1186/s13613-021-00929-y. PMID:34601646. IF:10,318.
Peñuelas O, Frutos-Vivar F, Muriel A, Mancebo J, García-Jiménez A, de Pablo R, Valledor M, Ferrer M, León M, Quiroga JM, Temprano S, Vallverdú I, Fernández R, Gordo F, Anzueto A, Esteban A. Mechanical ventilation in Spain, 1998-2016: Epidemiology and outcomes. Medicina Intensiva (Engl Ed). 2021;45(1):3-13. English, Spanish. DOI:10.1016/j.medin.2020.04.024. PMID: 32723483. IF:2,799.
Pham T, Montanya J, Telias I, Piraino T, Magrans R, Coudroy R, Damiani LF, Artigas RM, Madorno M, Blanch L, Brochard L, Mancebo J, Papazian L. Automated detection and quantification of reverse triggering effort under mechanical ventilation. CRITICAL CARE. 2021; 25(1):60. DOI:10.1186/s13054-020-03387-3. PMID:33588912. IF:19,334.
Pham T, Pesenti A, Bellani G, Rubenfeld G, Fan E, Bugedo G, Lorente JA, Fernandes AD, Van F, Bruhn A, Rios F, Esteban A, Gattinoni L, Larsson A, McAuley DF, Ranieri M, Thompson BT, Wrigge H, Brochard LJ, Laffey JG, Mancebo J, Schomer AM. Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study. EUROPEAN RESPIRATORY JOURNAL. 2021; 57(6):2003317. DOI:10.1183/13993003.03317-2020. PMID:33334944. IF:33,795.
Robba C, Citerio G, Taccone FS, Galimberti S, Rebora P, Vargiolu A, Pelosi P, Mancebo J, Laffey J. Multicentre observational study on practice of ventilation in brain injured patients: the VENTIBRAIN study protocol. BMJ Open. 2021; 11(8):e047100. DOI:10.1136/bmjopen-2020-047100. PMID:34380722. IF:3,006.
Tomasa TM, Sabater J, Pérez M, Ortiz P, Díaz Y, Navas A, Betbesé A, Rodríguez M, Ibarz M, Olmo A, Oliva I, Rovira C, Cano S, Vendrell E, Catalan RM, Miralbés M, González de Molina J, Xirgu J, Marcos P. Augmented renal clearance. An unnoticed relevant event. SCIENCE PROGRESS. 2021; 104(2):368504211018580. DOI:10.1177/00368504211018580. PMID:34078190. IF:1,512.

presentació

Principals línies de recerca

Insuficiència respiratòria aguda i ventilació artificial

Ventilació no invasiva.
Noves formes de ventilació: ventilació assistida proporcional i NAVA.
Decúbit pron en la síndrome de disfunció respiratòria aguda (SDRA).
Retirada de ventilació artificial.
Sistemes de ventilació d’experts.
La son i la ventilació artificial.
Mobilització primerenca i activa del pacient crític.
Eliminació de CO2 extracorpori en pacients amb SDRA.
Administració d’oxigen d’alt flux per cànula nasal en la fase posterior a la extubació.
Prevalença d’interaccions medicamentoses en la unitat de cures intensives.

Estudi de la utilitat de nous biomarcadors en pacients críticament malalts

BNP en la retirada de la ventilació mecànica.
Ús de la proteïna NGAL en el pronòstic renal dels pacients malalts crítics.
Control estricte de la glucèmia en pacients malalts crítics.
Profilaxi de la lesió de la mucosa gàstrica aguda en pacients malalts crítics.
Estudi dels efectes hemodinàmics de diferents fàrmacs antipirètics en pacients malalts crítics.
Influència del canvi de posició de decúbit supí a la pressió intraabdominal.

Reptes

Consolidar la investigació clínica i fisiològica en la ventilació en pacients crítics a través de xarxes multicèntriques i multinacionals.
Crear un grup estable i ben entrenat d’investigadors en aquesta disciplina.

equip

Coordinació del grup

MORAN CHORRO, INDALECIO FGS
imoran@santpau.cat

Membres

producció científica

Publicacions 2022

(JIF 2022)

Amado L, Rodríguez R, Bellani G, Pham T, Fan E, Madotto F, Laffey JG, Pesenti A, Brochard L, Esteban A, Gattinoni L, van F, Ranieri M, Rubenfeld G, Taylor B, Slutsky AS, Rios F, Van F, Sottiaux T, Lora FS, Azevedo LC, Bugedo G, Gonzalez M, Silesky J, Cerny V, Jibaja M, Wrigge H, Matamis D, Ranero JL, Amin P, Hashemian SM, Clarkson K, Kurahashi K, Villagomez A, et al. [Mancebo J]. Mechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study. Journal of Intensive Care. 2022; 10(1):55. DOI:10.1186/s40560-022-00648-x. IF:7,1 (Q1/3D). Document type: Article.
Baldirà J, Morán I, Marruecos L. Banisteriopsis caapi/Psychotria viridis. In: Toxic Plants. Reports, studies and research 2022. Ministry of Health. Publications Center, 2022; 49-52. https://cpage.mpr.gob.es NIPO en linea: 133-22-020-8. Document type: Book chapter.
Baldirà J, Morán I, Marruecos L. Coriaria myrtifolia. Roldón. In: Toxic Plants. Reports, studies and research 2022. Ministry of Health. Publications Center, 2022; 85-87. https://cpage.mpr.gob.es. NIPO en linea: 133-22-020-8. Document type: Book chapter.
Baldirà J, Morán I, Marruecos L. Hydrangea macrophylla. In: Toxic Plants. Reports, studies and research 2022. Ministry of Health. Publications Center, 2022; 124-126. https://cpage.mpr.gob.es NIPO en linea: 133-22-020-8. Document type: Book chapter.
Baldirà J, Morán I, Marruecos L. Narcissus spp. I: Toxic Plants. Reports, studies and research 2022. Ministry of Health. Publications Center, 2022; 172-174. https://cpage.mpr.gob.es. NIPO en linea: 133-22-020-8. Document type: Book chapter.
Baldirà J, Morán I, Marruecos L. Oenanthe crocata. Nabo del diablo. In: Toxic Plants. Reports, studies and research 2022. Ministry of Health. Publications Center, 2022; 184-187. https://cpage.mpr.gob.es. NIPO en linea: 133-22-020-8. Document type: Book chapter.
Baldirà J, Morán I, Marruecos L. Senecio jacobea. Hierba de Santiago. In: Toxic Plants. Reports, studies and research 2022. Ministry of Health. Publications Center, 2022; 222-224. https://cpage.mpr.gob.es. NIPO en linea: 133-22-020-8. Document type: Book chapter.
Belvís R, Morollón N, Cortés E, Morán I. Tabún, sarín, somán, VX y novichoks: agentes neurotóxicos organofosforados con finalidad bélica o criminal. 2022; 17(2). DOI:10.24875/KRANION.M22000030. Document type: Review.
Brault C, Mancebo J, Montero JCS, Bentall T, Burns K, Piraino T, Lellouche F, Bouchard PA, Charbonney E, Carteaux G, Maraffi T, Beduneau G, Mercat A, Skrobik Y, Zuo F, Lafreniere M, Thorpe K, Brochard L, Bosma KJ. The PROMIZING trial enrollment algorithm for early identification of patients ready for unassisted breathing. CRITICAL CARE. 2022; 26(1):188. DOI:10.1186/s13054-022-04063-4. PMID:35739553. IF:15,1 (Q1/1D). Document type: Article.
Chastre J, François B, Bourgeois M, Komnos A, Ferrer R, Rahav G, De Schryver N, Lepape A, Koksal I, Luyt C-E, Sánchez M, Torres A, Eggimann P, Koulenti D, Holland TL, Ali O, Shoemaker K, Ren P, Sauser J, Ruzin A, Tabor DE, Akhgar A, Wu Y, Jiang Y, DiGiandomenico A, Colbert S, Vandamme D, Coenjaerts F, Malhotra S, Timbermont L, Oliver A, Barraud O, et al. [Vera P]. Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial. CRITICAL CARE. 2022; 26(1):355. DOI:10.1186/s13054-022-04204-9. PMID:36380312. IF:15,1 (Q1/1D). Document type: Article.
Co-author of the Book: Algorithms of nutritional intervention in the critically ill Publishing House: Health and Editions, S.L. Edition: Second. ISBN: 978‑84‑18351‑74‑7 Publication date: 01/06/2022. List of authors in alphabetical order, page 6 (Paula Vera). Book pages: 1-94. Document type: Book.
Frutos F, Peñuelas O, Muriel A, Mancebo J, García A, de Pablo R, Valledor M, Ferrer M, León M, Quiroga JM, Temprano S, Vallverdú I, Fernández R, Gordo F, Anzueto A, Esteban A. Mechanical ventilation in Spain, 1998-2016: changes in the disconnection of mechanical ventilation. Medicina Intensiva. 2022; 46(7). DOI:10.1016/j.medin.2021.04.005. PMID:34092422. IF:3 (Q3/7D). Document type: Article.
Gomila Sintes C, Bernal S, Rojas E, Flores Orella MN, Leoz P, Betbesé Roig AJ. Favism in the elderly. Archives of Clinical and Medical Case Reports. 2022;6(4):582-585. DOI: 10.26502/acmcr.96550521. Document type: Article.
Lopez JC, Grau T, Trujillano J, Garcia C, Mor E, Bordeje ML, Portugal E, Lorencio C, Vera P, Macaya L, Martinez JF, Mateu L, Gero M, Gastaldo R, Vila B, Flordelis JL, Montejo JC, Servia L, ENPIC GRP. The Effect of Enteral Immunonutrition in the Intensive Care Unit: Does It Impact on Outcomes?. 2022; 14(9):1904. DOI:10.3390/nu14091904. PMID:35565870. IF:5,9 (Q1/2D). Document type: Article.
Maddali MV, Churpek M, Rezoagli E, Zhuo H, Zhao W, He J, Delucchi KL, Wickersham N, McNeil JB, Jauregui A, Ke S, Vessel K, Gomez A, Hendrickson CM, Kangelaris KN, Sarma A, Leligdowicz A, Liu KD, Matthay MA, Ware LB, Laffey JG, Bellani G, Calfee CS, Sinha P, Rios F, Van F, Sottiaux T, Lora FS, Azevedo LC, Fan E, Bugedo G, Qiu H, Gonzalez M, Silesky J, Cerny V, et al. [Mancebo J]. Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis. Lancet Respiratory Medicine. 2022; 10(4). DOI:10.1016/S2213-2600(21)00461-6. PMID:35026177. IF:76,2 (Q1/1D). Document type: Article.
Maggiore SM, Jaber S, Grieco DL, Mancebo J, Zakynthinos S, Demoule A, Ricard J-D, Navalesi P, Vaschetto R, Hraiech S, Klouche K, Frat J-P, Lemiale V, Fanelli V, Chanques G, Natalini D, Ischaki E, Reuter D, Morán I, Combe BL, Longhini F, De Gaetano A, Ranieri VM, Brochard LJ, Antonelli M, RINO Trial Study G. High-Flow Versus VenturiMask Oxygen Therapy to Prevent Reintubation in Hypoxemic Patients after Extubation: A Multicenter Randomized Clinical Trial. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022; 206(12). DOI:10.1164/rccm.202201-0065OC. PMID:35849787. IF:24,7 (Q1/1D). Document type: Article.
Mateos A, Betbesé AJ, Guix EM. Fundamental concepts for the management of continuous replacement therapies. Enfermeria Intensiva. 2022; 33. DOI:10.1016/j.enfi.2021.06.003. Document type: Review.
Morales L, Mancebo J, Del Sorbo L. Hypercapnia and extracorporeal carbon dioxide removal (ECCO2R) in the acute respiratory distress syndrome. Signa Vitae. 2022; 18(5). DOI:10.22514/sv.2022.046. IF:1,1 (Q4/9D). Document type: Review.
Munshi L, Mancebo J, Brochard LJ. Noninvasive Respiratory Support for Adults with Acute Respiratory Failure. NEW ENGLAND JOURNAL OF MEDICINE. 2022; 387(18). DOI:10.1056/NEJMra2204556. PMID:36322846. IF:158,5 (Q1/1D). Document type: Review.
Nasa P, Azoulay E, Chakrabarti A, Divatia JV, Jain R, Rodrigues C, Rosenthal VD, Alhazzani W, Arabi YM, Bakker J, Bassetti M, De Waele J, Dimopoulos G, Du B, Einav S, Evans L, Finfer S, Guerin C, Hammond NE, Jaber S, Kleinpell RM, Koh Y, Kollef M, Levy MM, Machado FR, Mancebo J, Martin I, Mer M, Niederman MS, Pelosi P, Perner A, Peter JV, Phua J, Piquilloud L, Pletz MW, Rhodes A, Schultz MJ, Singer M, Timsit JF, Venkatesh B, Vincent JL, Welte T, Myatra S. Infection control in the intensive care unit: expert consensus statements for SARS-CoV-2 using a Delphi method. LANCET INFECTIOUS DISEASES. 2022; 22(3):e74-e87. DOI:10.1016/S1473-3099(21)00626-5. PMID:34774188. IF:56,3 (Q1/1D). Document type: Review.
Pisani L, Algera AG, Neto AS, Azevedo LC, Paulus F, de Abreu MG, Pelosi P, Dondorp AM, Bellani G, Laffey JG, Schultz MJ, Martinez A, Leal L, Jorge A, de Oliveira M, Neto JA, Piras C, Moreira CL, Braga P, Dalcomune DM, Ribeiro de Carvalho AG, Gondim LAR, Castelo Branco Reis LM, da Cunha Ribeiro D, de Assis L, Campos RS, Fernandez Versiani dos Anjos JC, Bruzzi F, et al. [Mancebo J]. Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute respiratory distress syndrome: a pooled analysis of four observational studies. Lancet Global Health. 2022; 10(2). DOI:10.1016/S2214-109X(21)00485-X. PMID:34914899. IF:34,3 (Q1/1D). Document type: Article.
Riera P, Sole N, Suarez JC, Lopez PA, Fonts N, Rodriguez N, de Gamarra EF, Moran I. Drug-drug interactions in an intensive care unit and comparison of updates in two databases. Farmacia Hospitalaria. 2022; 46(5). DOI:10.7399/fh.13180. PMID:36183229. Document type: Article.
Sassoon CS, Mancebo J. The Double-edged Sword of Reverse Triggering: Impact on the Diaphragm. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022; 205(6). DOI:10.1164/rccm.202201-0099ED. PMID:35139008. IF:24,7 (Q1/1D). Document type: Editorial material.
Servia L, Lopez JC, Grau T, Trujillano J, Bordeje ML, Mor E, Portugal E, Lorencio C, Montejo JC, Vera P, Macaya L, Martinez JF, Iglesias R, Monge D, Flordelis JL, Llorente B, Menor EM, de Lagran IM, Yebenes JC. Evaluation of Nutritional Practices in the Critical Care patient (The ENPIC study): Does nutrition really affect ICU mortality?. Clinical Nutrition Espen. 2022; 47. DOI:10.1016/j.clnesp.2021.11.018. PMID:35063222. Document type: Article.
Suárez JC, Caballero AC, Martín L, Mancebo J. Immune effector cell-associated neurotoxicity syndrome: A therapeutic approach in the critically ill. Medicina Intensiva. 2022; 46(4). DOI:10.1016/j.medin.2020.06.014. PMID:32873409. IF:3 (Q3/7D). Document type: Article.
Torrego A, Muñoz AM, Lucena CM, Castro P, López L, Badía JR, Betbesé A, Ramirez J, Andreo F, Fernández M-T, Fabra M, Pajares V, Agustí C. Safety and Feasibility of Transbronchial Cryobiopsy in Mechanically Ventilated Patients. ARCHIVOS DE BRONCONEUMOLOGIA. 2022; 58(8). DOI:10.1016/j.arbres.2021.11.005. PMID:35312520. IF:8 (Q1/2D). Document type: Letter.
Vidal P, Díaz E, Aguilar E, Amezaga R, Ballesteros MÁ, Bodí MA, Bordejé ML, Garnacho J, García M, López M, Martín I, Ochagavía A, Ramírez P, Alcántara S, Andaluz D, Badallo O, Barrasa H, Borges M, Castellanos Á, Estella Á, Ferrer R, Fraile V, Fuset M, Giménez C, González C, Hernández A, Igeño JC, Iglesias D, Jiménez JJ, Llanos C, Llompart JA, López V, et al. [Zapata L]. Recommendations for the management of critically ill patients with COVID-19 in Intensive Care Units. Medicina Intensiva. 2022; 46(2). DOI:10.1016/j.medin.2021.08.011. PMID:34545260. IF:3 (Q3/7D). Document type: Article.
Vidal P, Díaz E, Aguilar E, Amezaga R, Ballesteros MÁ, Bodí MA, Bordejé ML, Garnacho J, García M, López M, Martín I, Ochagavía A, Ramírez P, Alcántara S, Andaluz D, Badallo O, Barrasa H, Borges M, Castellanos Á, Estella Á, Ferrer R, Fraile V, Fuset M, Giménez C, González C, Hernández A, Igeño JC, Iglesias D, Jiménez JJ, Llanos C, Llompart JA, López V, et al. [Zapata L]. Recommendations for the management of critically ill patients with COVID-19 in Intensive Care Units. Medicina Intensiva. 2022; 46(2). DOI:10.1016/j.medine.2021.11.019. PMID:34903475. IF:3 (Q3/7D). Document type: Article/Practice guideline.
Wendel PD, Mas A, Gonzalez C, Ferrer R, Manez R, Masclans JR, Sandoval E, Vera P, Trenado J, Fernandez R, Sirvent JM, Martinez M, Ibarz M, Garro P, Lopera JL, Bodi M, Yebenes JC, Triginer C, Vallverdu I, Baro A, Bodi F, Saludes P, Valencia M, Roche F, Huerta A, Cambra FJ, Barbera C, Echevarria J, Penuelas O, Mancebo J, UCIsCAT GRP. Non-invasive oxygenation support in acutely hypoxemic COVID-19 patients admitted to the ICU: a multicenter observational retrospective study. CRITICAL CARE. 2022; 26(1):37. DOI:10.1186/s13054-022-03905-5. PMID:35135588. IF:15,1 (Q1/1D). Document type: Article.
Zapata L, Suarez JC, Flores MN, Morales EM, Segarra A, Santos JA. Acute cor pulmonale in patients with acute respiratory distress syndrome due to COVID-19. Medicina Intensiva. 2022; 46(11). DOI:10.1016/j.medin.2021.12.016. PMID:35079192. IF:3 (Q3/7D). Document type: Letter.

Publicacions 2021

Albaiceta GM, Brochard L, Santos CCD, Fernandez R, Georgopoulos D, Girard T, Jubran A, Lopez J, Mancebo J, Pelosi P, Skrobik Y, Thille AW, Wilcox ME, Blanch L. The central nervous system during lung injury and mechanical ventilation: a narrative review. BRITISH JOURNAL OF ANAESTHESIA. 2021; 127(4). DOI:10.1016/j.bja.2021.05.038. PMID:34340836. IF:11,719.
Astigarraga P, Lerma FA, Zambrano CB, Costa RG, Vidal FG, Navarro RD, Suarez CR, Pallas TA, Montero JG, Vera P, Alemparte E. Epidemiology and prognosis of patients with a history of cancer admitted to intensive care. A multicenter observational study. Medicina Intensiva. 2021; 45(6). DOI:10.1016/j.medin.2020.01.013. PMID:32307264. IF:2,799.
Berenguer J, Borobia AM, Ryan P, Rodriguez J, Bellon JM, Jarrin I, Carratala J, Pachon J, Carcas AJ, Yllescas M, Arribas JR, López J, Pascual P, Pomar V, Rabella N, Benito N, Domingo P, Bonfill X, Mancebo J, MARTIN A. Development and validation of a prediction model for 30-day mortality in hospitalised patients with COVID-19: the COVID-19 SEIMC score. THORAX. 2021; 76(9). DOI:10.1136/thoraxjnl-2020-216001. PMID:33632764. IF:9,102.
Grieco DL, Maggiore SM, Roca O, Spinelli E, Patel BK, Thille AW, Barbas CSV, De Acilu MG, Cutuli SL, Bongiovanni F, Amato M, Frat JP, Mauri T, Kress JP, Mancebo J, Antonelli M. Non-invasive ventilatory support and high-flow nasal oxygen as first-line treatment of acute hypoxemic respiratory failure and ARDS. INTENSIVE CARE MEDICINE. 2021; 47(8). DOI:10.1007/s00134-021-06459-2. PMID:34232336. IF:41,787.
Gutierrez B, del Toro MD, Borobia AM, Carcas A, Jarrin I, Yllescas M, Ryan P, Pachon J, Carratala J, Berenguer J, Arribas JR, Rodriguez J, López J, Pascual P, Pomar V, Rabella N, Benito N, Domingo P, Bonfill X, Puig M, Mancebo J, Martinez G. Identification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19: a multicentre cohort study. LANCET INFECTIOUS DISEASES. 2021; 21(6). DOI:10.1016/S1473-3099(21)00019-0. PMID:33636145. IF:71,421.
Johnstone J, Meade M, Lauzier F, Marshall J, Duan E, Dionne J, Arabi YM, Heels D, Thabane L, Lamarche D, Surette M, Zytaruk N, Mehta S, Dodek P, McIntyre L, English S, Rochwerg B, Karachi T, Henderson W, Wood G, Ovakim D, Herridge M, Granton J, Wilcox ME, Goffi A, Stelfox HT, Niven D, Muscedere J, Lamontagne F, D’Aragon F, St C, Ball I, et al. [Mancebo J]. Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients A Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2021; 326(11). DOI:10.1001/jama.2021.13355. PMID:34546300. IF:157,335.
Lomeli M, Cenzano LD, Torres L, Chavarria U, Poblano M, Tendillo F, Blanch L, Mancebo J. Aggressive alveolar recruitment in ARDS: more shadows than lights. Medicina Intensiva. 2021; 45(7). DOI:10.1016/j.medin.202.0.03.008. IF:2,799.
Madotto F, McNicholas B, Rezoagli E, Pham T, Laffey JG, Bellani G, Mancebo J, Pesenti A. Death in hospital following ICU discharge: insights from the LUNG SAFE study. CRITICAL CARE. 2021; 25(1):144. DOI:10.1186/s13054-021-03465-0. PMID:33849625. IF:19,334.
Mauri T, Foti G, Fornari C, Grasselli G, Pinciroli R, Lovisari F, Tubiolo D, Volta CA, Spadaro S, Rona R, Rondelli E, Navalesi P, Garofalo E, Knafelj R, Gorjup V, Colombo R, Cortegiani A, Zhou JX, D’Andrea R, Calamai I, Gonzalez AV, Roca O, Grieco DL, Jovaisa T, Bampalis D, Becher T, Battaglini D, Ge HQ, Luz M, Constantin JM, Ranieri M, Guerin C, Mancebo J, et al. Sigh in Patients With Acute Hypoxemic Respiratory Failure and ARDS The PROTECTION Pilot Randomized Clinical Trial. CHEST. 2021; 159(4). DOI:10.1016/j.chest.2020.10.079. PMID:33197403. IF:10,262.
Nasa P, Azoulay E, Khanna AK, Jain R, Gupta S, Javeri Y, Juneja D, Rangappa P, Sundararajan K, Alhazzani W, Antonelli M, Arabi YM, Bakker J, Brochard LJ, Deane AM, Du B, Einav S, Esteban A, Gajic O, Galvagno SM, Guerin C, Jaber S, Khilnani GC, Koh Y, Lascarrou JB, Machado FR, Malbrain MLNG, Mancebo J, McCurdy MT, McGrath BA, Mehta S, et al. Expert consensus statements for the management of COVID-19-related acute respiratory failure using a Delphi method. CRITICAL CARE. 2021; 25(1):106. DOI:10.1186/s13054-021-03491-y. PMID:33726819. IF:19,334.
Penuelas O, del Campo L, de Aledo A, Anon JM, Rodriguez C, Mancebo J, Vera P, Ballesteros D, Jimenez J, Maseda E, Figueira JC, Franco N, Algaba A, Aviles JP, Diaz R, Abad B, Canabal A, Abella A, Gordo F, Garcia J, Suarez JG, Cedeno J, Martinez B, Manteiga E, Martinez O, Blancas R, Bardi T, Pestana D, Lorente JA, Muriel A, Esteban A, Frutos F. Long-term survival of mechanically ventilated patients with severe COVID-19: an observational cohort study. Annals of Intensive Care. 2021; 11(1):143. DOI:10.1186/s13613-021-00929-y. PMID:34601646. IF:10,318.
Peñuelas O, Frutos-Vivar F, Muriel A, Mancebo J, García-Jiménez A, de Pablo R, Valledor M, Ferrer M, León M, Quiroga JM, Temprano S, Vallverdú I, Fernández R, Gordo F, Anzueto A, Esteban A. Mechanical ventilation in Spain, 1998-2016: Epidemiology and outcomes. Medicina Intensiva (Engl Ed). 2021;45(1):3-13. English, Spanish. DOI:10.1016/j.medin.2020.04.024. PMID: 32723483. IF:2,799.
Pham T, Montanya J, Telias I, Piraino T, Magrans R, Coudroy R, Damiani LF, Artigas RM, Madorno M, Blanch L, Brochard L, Mancebo J, Papazian L. Automated detection and quantification of reverse triggering effort under mechanical ventilation. CRITICAL CARE. 2021; 25(1):60. DOI:10.1186/s13054-020-03387-3. PMID:33588912. IF:19,334.
Pham T, Pesenti A, Bellani G, Rubenfeld G, Fan E, Bugedo G, Lorente JA, Fernandes AD, Van F, Bruhn A, Rios F, Esteban A, Gattinoni L, Larsson A, McAuley DF, Ranieri M, Thompson BT, Wrigge H, Brochard LJ, Laffey JG, Mancebo J, Schomer AM. Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study. EUROPEAN RESPIRATORY JOURNAL. 2021; 57(6):2003317. DOI:10.1183/13993003.03317-2020. PMID:33334944. IF:33,795.
Robba C, Citerio G, Taccone FS, Galimberti S, Rebora P, Vargiolu A, Pelosi P, Mancebo J, Laffey J. Multicentre observational study on practice of ventilation in brain injured patients: the VENTIBRAIN study protocol. BMJ Open. 2021; 11(8):e047100. DOI:10.1136/bmjopen-2020-047100. PMID:34380722. IF:3,006.
Tomasa TM, Sabater J, Pérez M, Ortiz P, Díaz Y, Navas A, Betbesé A, Rodríguez M, Ibarz M, Olmo A, Oliva I, Rovira C, Cano S, Vendrell E, Catalan RM, Miralbés M, González de Molina J, Xirgu J, Marcos P. Augmented renal clearance. An unnoticed relevant event. SCIENCE PROGRESS. 2021; 104(2):368504211018580. DOI:10.1177/00368504211018580. PMID:34078190. IF:1,512.

GRUPS ASSOCIATS

Medicina Intensiva

Principals línies de recerca

Insuficiència respiratòria aguda i ventilació artificial

Estudi de la utilitat de nous biomarcadors en pacients críticament malalts

Reptes

Coordinació del grup

Membres

Publicacions 2022

Publicacions 2021

Principals línies de recerca

Insuficiència respiratòria aguda i ventilació artificial

Estudi de la utilitat de nous biomarcadors en pacients críticament malalts

Reptes

Coordinació del grup

Membres

Publicacions 2022

Publicacions 2021

Institut de recerca de l’hospital de la santa creu i sant pau